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1.发明申请Secreted Insecticidal Protein and Gene Compositions from Bacillus Thuringiensis and Uses Therefor 审中-公开苏云金芽孢杆菌的分泌杀虫蛋白和基因组成及其用途公开(公告)号：US20080040827A1
公开(公告)日：2008-02-14
申请号：US10581763
申请日：2004-12-14
Applicant: Judith Donovan , William Donovan , James Engleman , Thomas Malvar , John Pitkin
Inventor： Judith Donovan , William Donovan , James Engleman , Thomas Malvar , John Pitkin
CPC classification number: C07K14/32 , C07K14/325 , C12N15/8286
Abstract: The present invention relates to the isolation and characterization of nucleotide sequences encoding novel insecticidal proteins secreted into the extracellular space from Bacillus thuringiensis and related strains. The proteins are isolated from culture supernatants of Bacillus thuringiensis and related strains and display insecticidal activity against lepidopteran insects including European corn borer (ECB), tobacco budworm (TBW) and diamondback moth (DBM). Insecticidal proteins encoded by nucleotide sequences that hybridize under stringent conditions to the isolated and characterized nucleotide sequences are disclosed. Methods are disclosed for making and using transgenic cells and plants comprising the novel nucleotide sequence of the invention.
Abstract translation: 本发明涉及分离和表征编码从苏云金芽孢杆菌和相关菌株分泌到细胞外空间中的新型杀虫蛋白的核苷酸序列。 从苏云金芽孢杆菌和相关菌株的培养上清液中分离蛋白质，并显示对包括欧洲玉米螟（ECB），烟草芽孢杆菌（TBW）和小菜蛾（DBM）等鳞翅目昆虫的杀虫活性。 公开了在严格条件下与分离和表征的核苷酸序列杂交的核苷酸序列编码的杀虫蛋白。 公开了制备和使用包含本发明的新型核苷酸序列的转基因细胞和植物的方法。
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2.发明申请公开(公告)号：US20060191034A1
公开(公告)日：2006-08-24
申请号：US10563270
申请日：2004-07-06
Applicant: James Baum , Judith Donovan , William Donovan , James Engleman , Karina Krasomil-Osterfeld , John Pitkin , James Roberts
Inventor： James Baum , Judith Donovan , William Donovan , James Engleman , Karina Krasomil-Osterfeld , John Pitkin , James Roberts
IPC: A01H1/00 , C07H21/04 , C12N15/82 , C07K14/325 , A01N63/00
Abstract: The present invention relates to the isolation and characterization of nucleotide sequences encoding novel insecticidal proteins secreted into the extracellular space from Bacillus thuringiensis and related strains. The proteins are isolated from culture supernatants of Bacillus thuringiensis and related strains and display insecticidal activity against coleopteran insects including Colorado potato beetle (Lymantria dispar) and Southern Corn Rootworm (Diabrotica undecempunctata). Insecticidal proteins encoded by nucleotide sequences that hybridize to the isolated and characterized nucleotide sequences are disclosed. Also disclosed are methods of making and using transgenic cells and plants comprising the novel nucleotide sequence of the invention.
Abstract translation: 本发明涉及分离和表征编码从苏云金芽孢杆菌和相关菌株分泌到细胞外空间中的新型杀虫蛋白的核苷酸序列。 从苏云金芽孢杆菌和相关菌株的培养上清液中分离出蛋白质，并显示对包括科罗拉多马铃薯甲虫（Lymantria dispar）和南方玉米根虫（Diabrotica undecempunctata）在内的鞘翅目昆虫的杀虫活性。 公开了与分离和表征的核苷酸序列杂交的核苷酸序列编码的杀虫蛋白。 还公开了制备和使用包含本发明的新型核苷酸序列的转基因细胞和植物的方法。
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公开(公告)号：US20130276161A1
公开(公告)日：2013-10-17
申请号：US13566369
申请日：2012-08-03
Applicant: Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
Inventor： Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
IPC: C12N15/82
CPC classification number: C12N15/8273 , C07K14/415 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , G01N33/68 , G01N2333/415 , Y02A40/146
Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US08207092B2
公开(公告)日：2012-06-26
申请号：US12099101
申请日：2008-04-07
Applicant: Muhammad Bhatti , Ronald J. Brinker , Gerald M. Dill, Jr. , Paul C. C. Feng , Sio-Wai Hoi , Jennifer L. Jacobs , John Pitkin
Inventor： Muhammad Bhatti , Ronald J. Brinker , Gerald M. Dill, Jr. , Paul C. C. Feng , Sio-Wai Hoi , Jennifer L. Jacobs , John Pitkin
CPC classification number: A01N37/40 , A01H3/04 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12N15/8281 , C12N15/8282 , C12N15/8285 , Y02A40/146 , Y02A40/164 , A01N57/20 , A01N2300/00
Abstract: The present invention provides methods and compositions for improving plant health. In particular, application of dicamba or another substrate of DMO, or metabolites thereof including DCSA, to a plant confers tolerance to, or defense against, abiotic or biotic stresses such as oxidative stress including herbicide application, and plant disease, and enhances crop yield. Such application may be in combination with the application of another herbicide such as glyphosate.
Abstract translation: 本发明提供了改善植物健康的方法和组合物。 特别地，将麦草畏或其他DMO底物或其代谢产物（包括DCSA）施用于植物赋予非生物或生物胁迫的耐受性或防御性，例如包括除草剂施用在内的氧化应激和植物病害，并且提高作物产量。 这种应用可以与其它除草剂如草甘膦的应用组合。
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5.发明申请Secreted Insecticidal Protein and Gene Compositions from Bacillus Thuringiensis and Uses Therefor 有权苏云金芽孢杆菌的分泌杀虫蛋白和基因组成及其用途公开(公告)号：US20110283417A1
公开(公告)日：2011-11-17
申请号：US13171519
申请日：2011-06-29
Applicant: JUDITH DONOVAN , WILLIAM DONOVAN , JAMES ENGLEMAN , THOMAS MALVAR , JOHN PITKIN
Inventor： JUDITH DONOVAN , WILLIAM DONOVAN , JAMES ENGLEMAN , THOMAS MALVAR , JOHN PITKIN
IPC: A01H5/00 , C12N15/63 , C07K14/32 , G01N33/53 , A01N37/18 , C12Q1/68 , C12N15/82 , A01H5/10 , C12N15/31 , C12N5/10
CPC classification number: C07K14/32 , C07K14/325 , C12N15/8286
Abstract: The present invention relates to the isolation and characterization of nucleotide sequences encoding novel insecticidal proteins secreted into the extracellular space from Bacillus thuringiensis and related strains. The proteins are isolated from culture supernatants of Bacillus thuringiensis and related strains and display insecticidal activity against lepidopteran insects including European corn borer (ECB), tobacco budworm (TBW) and diamondback moth (DBM). Insecticidal proteins encoded by nucleotide sequences that hybridize under stringent conditions to the isolated and characterized nucleotide sequences are disclosed. Methods are disclosed for making and using transgenic cells and plants comprising the novel nucleotide sequence of the invention.
Abstract translation: 本发明涉及分离和表征编码从苏云金芽孢杆菌和相关菌株分泌到细胞外空间中的新型杀虫蛋白的核苷酸序列。 从苏云金芽孢杆菌和相关菌株的培养上清液中分离蛋白质，并显示对包括欧洲玉米螟（ECB），烟草芽孢杆菌（TBW）和小菜蛾（DBM）等鳞翅目昆虫的杀虫活性。 公开了在严格条件下与分离和表征的核苷酸序列杂交的核苷酸序列编码的杀虫蛋白。 公开了制备和使用包含本发明的新型核苷酸序列的转基因细胞和植物的方法。
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Patent Agency Ranking
公开(公告)号：US20110004955A1
公开(公告)日：2011-01-06
申请号：US12322120
申请日：2009-01-29
Applicant: Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
Inventor： Mark Abad , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Brian Hauge , Steve He , Jacqueline E. Heard , Ping Li , Linda Lutfiyya , Bradley McDill , Robert J. Meister , Peter Morrell , Anil Neelam , Marie Petracek , John Pitkin , M. S. Rajani , Maria F. Rodriguez , Thomas Ruff , T. V. Venkatesh , Xiaoyun Wu , Jianmin Zhao , Albert Iandolino , Monica Ravanello , Kraig Brustad , Paul Chomet , Julie Davis , Virginia Ursin , T. Ambika , Shobha Char , Savitha Madappa , Dhanalakshmi Ramachandra , S. Sangeetha , K. R. Vidya , K. Vijayalakshmi , Todd Dezwaan
CPC classification number: C12N15/8273 , C07K14/415 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , G01N33/68 , G01N2333/415 , Y02A40/146
Abstract: This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
Abstract translation: 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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公开(公告)号：US20100279866A1
公开(公告)日：2010-11-04
申请号：US12440173
申请日：2007-10-16
Applicant: Muhammad Bhatti , Paul C.C. Feng , John Pitkin , Sio-Wai Hoi
Inventor： Muhammad Bhatti , Paul C.C. Feng , John Pitkin , Sio-Wai Hoi
CPC classification number: A01N37/10 , A01H3/04 , A01N37/40 , A01N57/20 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12N15/8281 , C12N15/8282 , C12N15/8285 , Y02A40/146 , Y02A40/164 , A01N2300/00
Abstract: The present invention provides methods and compositions for improving plant health. In particular, application of dicamba or another substrate of DMO, or metabolites thereof including DCSA, to a plant confers tolerance to, or defense against, abiotic or biotic stresses such as oxidative stress including herbicide application, and plant disease, and enhances crop yield. Such application may be in combination with the application of another herbicide such as glyphosate.
Abstract translation: 本发明提供了改善植物健康的方法和组合物。 特别地，将麦草畏或其他DMO底物或其代谢产物（包括DCSA）施用于植物赋予非生物或生物胁迫的耐受性或防御性，例如包括除草剂施用在内的氧化应激和植物病害，并且提高作物产量。 这种应用可以与其它除草剂如草甘膦的应用组合。
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公开(公告)号：US08754011B2
公开(公告)日：2014-06-17
申请号：US12440173
申请日：2007-10-16
Applicant: Muhammad Bhatti , Paul C. C. Feng , John Pitkin
Inventor： Muhammad Bhatti , Paul C. C. Feng , John Pitkin
CPC classification number: A01N37/10 , A01H3/04 , A01N37/40 , A01N57/20 , C12N15/8261 , C12N15/8271 , C12N15/8274 , C12N15/8275 , C12N15/8281 , C12N15/8282 , C12N15/8285 , Y02A40/146 , Y02A40/164 , A01N2300/00
Abstract: The present invention provides methods and compositions for improving plant health. In particular, application of dicamba or another substrate of DMO, or metabolites thereof including DCSA, to a plant confers tolerance to, or defense against, abiotic or biotic stresses such as oxidative stress including herbicide application, and plant disease, and enhances crop yield. Such application may be in combination with the application of another herbicide such as glyphosate.
Abstract translation: 本发明提供了改善植物健康的方法和组合物。 特别地，将麦草畏或其他DMO底物或其代谢产物（包括DCSA）施用于植物赋予非生物或生物胁迫的耐受性或防御性，例如包括除草剂施用在内的氧化应激和植物病害，并且提高作物产量。 这种应用可以与其它除草剂如草甘膦的应用组合。
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9.发明授权Secreted insecticidal protein and gene compositions from Bacillus thuringiensis and uses therefor 有权来自苏云金芽孢杆菌的分泌的杀虫蛋白和基因组成，并用于此公开(公告)号：US08569583B2
公开(公告)日：2013-10-29
申请号：US13171519
申请日：2011-06-29
Applicant: Judith Donovan , William Donovan , James Engleman , Thomas Malvar , John Pitkin
Inventor： Judith Donovan , William Donovan , James Engleman , Thomas Malvar , John Pitkin
IPC: A01H5/00 , A01H5/10 , C12N15/82 , C12N15/32 , C07K14/325
CPC classification number: C07K14/32 , C07K14/325 , C12N15/8286
Abstract: The present invention relates to the isolation and characterization of nucleotide sequences encoding novel insecticidal proteins secreted into the extracellular space from Bacillus thuringiensis and related strains. The proteins are isolated from culture supernatants of Bacillus thuringiensis and related strains and display insecticidal activity against lepidopteran insects including European corn borer (ECB), tobacco budworm (TBW) and diamondback moth (DBM). Insecticidal proteins encoded by nucleotide sequences that hybridize under stringent conditions to the isolated and characterized nucleotide sequences are disclosed. Methods are disclosed for making and using transgenic cells and plants comprising the novel nucleotide sequence of the invention.
Abstract translation: 本发明涉及分离和表征编码从苏云金芽孢杆菌和相关菌株分泌到细胞外空间中的新型杀虫蛋白的核苷酸序列。 从苏云金芽孢杆菌和相关菌株的培养上清液中分离蛋白质，并显示对包括欧洲玉米螟（ECB），烟草芽孢杆菌（TBW）和小菜蛾（DBM）等鳞翅目昆虫的杀虫活性。 公开了在严格条件下与分离和表征的核苷酸序列杂交的核苷酸序列编码的杀虫蛋白。 公开了制备和使用包含本发明的新型核苷酸序列的转基因细胞和植物的方法。
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10.发明申请公开(公告)号：US20110191896A1
公开(公告)日：2011-08-04
申请号：US12935275
申请日：2009-04-13
Applicant: John Pitkin , Steve Screen , Zhidong Xie
Inventor： John Pitkin , Steve Screen , Zhidong Xie
CPC classification number: C12N15/8271 , A01N37/46 , A23K10/12 , A23L7/10 , A23L7/198 , A23L11/07 , C07K14/415
Abstract: The present invention discloses novel plant homologs of the Arabidopsis peptide atPEP1. atPEP peptides in Arabidopsis are involved in the amplification of defense pathways involved in innate immunity against microbial pathogens. Homologs to atPEP1 identified in soy, corn, rice, wheat, and canola sequence databases are potential sources for transgenes to enhance crop yield through resistance to biotic and/or abiotic stresses. Chimeric genes comprising sequences from mature and precursor plant defense response polypeptides from a given species, and from different species, as well as the encoded polypeptide sequences, are also described.
Abstract translation: 本发明公开了PEP1中拟南芥肽的新型植物同系物。 拟南芥中的atPEP肽参与了涉及针对微生物病原体的先天免疫的防御途径的扩增。 在大豆，玉米，水稻，小麦和卡诺拉序列数据库中鉴定出的atPEP1的同源物是转基因通过抵抗生物和/或非生物胁迫来提高作物产量的潜在来源。 还描述了包含来自给定物种和来自不同物种的成熟和前体植物防御反应多肽的序列的嵌合基因以及编码的多肽序列。
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