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公开(公告)号：US20050042768A1
公开(公告)日：2005-02-24
申请号：US10643424
申请日：2003-08-19
申请人： Joseph Fredrick
发明人： Joseph Fredrick
IPC分类号： B01J19/00 , B01L3/00 , B01L7/00 , B01L9/00 , C40B40/06 , C40B40/10 , C40B60/14 , G01N1/31 , G01N35/00 , B01L11/00
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00286 , B01J2219/00344 , B01J2219/00353 , B01J2219/00389 , B01J2219/00495 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00677 , B01J2219/00691 , B01J2219/00722 , B01J2219/00725 , B01L3/502 , B01L7/52 , B01L9/52 , B01L2200/0678 , B01L2300/0636 , B01L2300/0819 , B01L2300/0822 , B01L2300/0877 , B01L2300/10 , B01L2400/0457 , C40B40/06 , C40B40/10 , C40B60/14 , G01N1/312 , G01N2035/00158 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
摘要： Devices, apparatus and methods are disclosed for carrying out processing steps involved in chemical reactions such as hybridization reactions conducted on the surface of a substrate comprising chemical compounds such as biopolymer features. A device comprises a housing comprising a housing chamber. The housing comprises an opening through which a substrate may be inserted into the housing chamber. The device may also comprise a lift mechanism for moving the substrate in and out of the housing chamber in a controlled manner. At least one inlet may be in fluid communication with the housing chamber and at least one outlet may be in fluid communication with the housing chamber. Also disclosed are methods wherein the surface is brought into contact with a processing fluid; and, then, the surface is removed from contact with the fluid in a controlled manner at a rate that substantially eliminates droplet formation of the fluid on the surface of the substrate.
摘要翻译： 公开了用于进行涉及化学反应的加工步骤的装置，装置和方法，例如在包含诸如生物聚合物特征的化学化合物的基材的表面上进行的杂交反应。 一种装置包括壳体，该壳体包括壳体室。 壳体包括开口，衬底可以通过该开口插入到壳体室中。 该装置还可以包括用于以受控的方式将衬底移入和移出壳体室的提升机构。 至少一个入口可以与容纳室流体连通，并且至少一个出口可以与容纳室流体连通。 还公开了一种方法，其中表面与处理流体接触; 然后，以基本上消除基板表面上的流体液滴形成的速度，以受控的方式将表面从液体中除去。
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2.发明授权Safened pesticidal resin compositions for controlling soil borne pests and process for the preparation thereof 失效用于控制土壤有害生物的安全杀虫树脂组合物及其制备方法
公开(公告)号：US5650161A
公开(公告)日：1997-07-22
申请号：US464190
申请日：1995-06-05
摘要： The present invention relates to novel dry-blended extrudable pesticidal resin composition, extruded pesticidal resin compositions and pelletized pesticidal resin compositions comprising, as the active ingredient, O,O-diethyl S-[[1,1-dimethylethyl)thio]methyl]phosphorodithioate, O,O-diethyl S-(ethylthiomethyl)phosphorodithioate or a pesticidal chemical wherein said technical grade of said pesticidal chemical has a dermal and/or oral LD50, as measured on rats or rabbits of less than 50 mg/kg. The novel compositions of the present invention are characterized by markedly reduced mammalian toxicity and increased pesticide stability and are essentially free of dust. Further, the present invention also relates to a process for preparing the present safened pesticidal resin compositions.
摘要翻译： 本发明涉及新型干混挤出农药树脂组合物，挤出农药树脂组合物和颗粒化农药树脂组合物，其包含作为活性成分的O，O-二乙基S - [[1,1-二甲基乙基]硫基]甲基]二硫代磷酸酯 ，O-二乙基S-（乙硫基甲基）二硫代磷酸酯或杀虫化学品，其中所述杀虫化学品的所述工业级具有皮肤和/或口服LD 50，如在大鼠或兔子上测量的小于50mg / kg。 本发明的新型组合物的特征在于显着降低的哺乳动物毒性和增加的农药稳定性，并且基本上不含灰尘。 此外，本发明还涉及本发明的安全杀虫树脂组合物的制备方法。
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公开(公告)号：USD470770S1
公开(公告)日：2003-02-25
申请号：US29148341
申请日：2001-09-10
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4.发明授权Safened pesticidal resin composition for controlling soil borne pests and process for the preparation thereof 失效用于控制土壤有害生物的安全杀虫树脂组合物及其制备方法公开(公告)号：US06193990B1
公开(公告)日：2001-02-27
申请号：US08239850
申请日：1994-05-09
IPC分类号： A01N2508
CPC分类号： A01N25/10 , A01N25/32 , A01N57/12 , C08K5/0016 , A01N25/02 , A01N2300/00 , C08L27/06
摘要： The present invention relates to novel dry-blended extrudable pesticidal resin composition, extruded pesticidal resin compositions and pelletized pesticidal resin compositions comprising, as the active ingredient, O,O-diethyl S-[[1,1-dimethylethyl)thio]-methyl]phosphorodithioate, O,O-diethyl S-(ethylthio-methyl)phosphorodithioate or a pesticidal chemical wherein said technical grade of said pesticidal chemical has a dermal and/or oral LD50, as measured on rats or rabbits of less than 50 mg/kg. The novel compositions of the present invention are characterized by markedly reduced mammalian toxicity and increased pesticide stability and are essentially free of dust. Further, the present invention also relates to a process for preparing the present safened pesticidal resin compositions.
摘要翻译： 本发明涉及新型干混挤出农药树脂组合物，挤出农药树脂组合物和颗粒化杀虫树脂组合物，其包含作为活性成分的O，O-二乙基S - [[1,1-二甲基乙基]硫基] - 甲基] 二硫代磷酸酯，O，O-二乙基S-（乙硫基 - 甲基）二硫代磷酸酯或杀虫化学品，其中所述杀虫化学品的所述工业级别具有皮肤和/或口服LD 50，如在大鼠或兔子上测量的小于50mg / kg。 本发明的新型组合物的特征在于显着降低的哺乳动物毒性和增加的农药稳定性，并且基本上不含灰尘。 此外，本发明还涉及本发明的安全杀虫树脂组合物的制备方法。
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5.发明申请公开(公告)号：US20060257922A1
公开(公告)日：2006-11-16
申请号：US11490635
申请日：2006-07-21
申请人： Joseph Fredrick , Jacqueline Tso
发明人： Joseph Fredrick , Jacqueline Tso
CPC分类号： C12Q1/6876 , C12Q1/6837 , C12Q2600/166 , C12Q2537/143
摘要： Methods and compositions for detecting cross-contamination between samples contacted with different arrays of a multi-array substrate are provided. The methods involve contacting sample to arrays of a multi-array substrate that contains cross-contamination probes in each of its arrays, and evaluating the resultant sample contacted arrays for cross-contamination between the samples. In many embodiments, the arrays of the multi-array substrate contain a set of cross-contamination probes for a corresponding set of cross-contamination targets in the sample(s). Kits and systems are provided for performing the invention. The subject methods may be used in a variety of different applications, such as gene expression analysis, DNA sequencing, mutation detection, as well as other genomics and proteomics applications.
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公开(公告)号：US20050244972A1
公开(公告)日：2005-11-03
申请号：US11105748
申请日：2005-04-13
申请人： Richard Hilson , Edward Donlon , Donald Schremp , Laurence Shea , Carol Schembri , Joseph Fredrick
发明人： Richard Hilson , Edward Donlon , Donald Schremp , Laurence Shea , Carol Schembri , Joseph Fredrick
CPC分类号： G01N35/04 , G01N35/00029 , G01N2035/00158 , G01N2035/0444 , Y10T436/11 , Y10T436/113332 , Y10T436/114998 , Y10T436/142222 , Y10T436/143333
摘要： Apparatus and methods are disclosed for processing samples on the surface of supports that are contained in support housings. Biopolymer features are attached to the surfaces of the supports. An apparatus comprises an input element, a holding device for holding a plurality of support housings, one or more fluid dispensing stations, and an output element. Each of the support housings contains a support having attached thereto a plurality of biopolymer features. The holding device is movably mounted with respect to other components of the apparatus. The holding device is adapted to receive a support housing from the input element. The output element is adapted to receive a support housing from the holding device. The apparatus is adapted to index each support housing for a predetermined operation. In use, each of the support housings is moved to one or more processing stations by means of the movable holding device. The location and identity of each of the support housings is indexed. Fluid is applied to the surface of each of the supports at the processing stations to process the samples. Each of the support housings is moved away from the fluid dispensing stations, and fluid is physically removed from each of the supports within the support housings.
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公开(公告)号：US20050048506A1
公开(公告)日：2005-03-03
申请号：US10655477
申请日：2003-09-03
申请人： Joseph Fredrick , Jacqueline Tso
发明人： Joseph Fredrick , Jacqueline Tso
CPC分类号： B01J19/0046 , B01J2219/00527 , B01J2219/00542 , B01J2219/00545 , B01J2219/00576 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00659 , B01J2219/00693 , B01J2219/00722 , C40B40/08 , C40B70/00
摘要： Methods and compositions for encoding array information on an array are provided. The methods involve contacting an array containing one or more array information features with a sample containing target that binds to at least one of the one or more array information features to produce at least one signal that provides information about the array. In many embodiments the signal is a symbol or a code, such as binary-code or non-binary-code, that provides the information about the array. Kits and systems are provided for performing the invention.
摘要翻译： 提供了用于编码阵列上阵列信息的方法和组合。 所述方法包括将包含一个或多个阵列信息特征的阵列与包含目标的样本接触，所述样本包含与所述一个或多个阵列信息特征中的至少一个结合的至少一个阵列信息特征，以产生提供关于所述阵列的信息的至少 在许多实施例中，信号是提供关于阵列的信息的符号或代码，例如二进制代码或非二进制代码。 提供了用于执行本发明的套件和系统。
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公开(公告)号：US636191A
公开(公告)日：1899-10-31
申请号：US1899705101
申请日：1899-02-09
申请人： H C SIMMS , F B ENSLOW , WRIGHT JOSEPH FREDRICK
CPC分类号： G01C15/10
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