MEMS INTERSTITIAL PROTHROMBIN TIME TEST
    2.
    发明申请
    MEMS INTERSTITIAL PROTHROMBIN TIME TEST 失效
    MEMS INTERSTITIAL PROTHROMBIN时间测试

    公开(公告)号:US20090093697A1

    公开(公告)日:2009-04-09

    申请号:US12189509

    申请日:2008-08-11

    IPC分类号: A61B5/145

    CPC分类号: A61B5/02035

    摘要: A method of determining a prothrombin time is disclosed. A mediator is applied to a stratum corneum. The stratum corneum is penetrated to allow the mediator to enter a region containing interstitial fluid and interact with at least one capillary, causing blood and/or blood components to leak from the at least one capillary into the region containing interstitial fluid. A characteristic affected by the blood and/or blood components is measured in the region containing interstitial fluid which correlates to the prothrombin time. A system for measuring prothrombin time is also disclosed. The system has a mediator, one or more microneedles, and a processor directly or indirectly coupled to the one or more microneedles and configured to determine a coagulation change in blood or blood components in a region around the one or more microneedles after the one or more microneedles penetrate a stratum corneum.

    摘要翻译: 公开了一种确定凝血酶原时间的方法。 将介体应用于角质层。 穿透角质层以允许介体进入含有组织液的区域并与至少一个毛细管相互作用,导致血液和/或血液成分从至少一个毛细管渗漏到含有间质液的区域中。 在与凝血酶原时间相关的含有间质液的区域中测量受血液和/或血液成分影响的特征。 还公开了一种用于测量凝血酶原时间的系统。 该系统具有介体,一个或多个微针,以及处理器,其直接或间接地耦合到所述一个或多个微针并且被配置为确定在所述一个或多个微针之后的所述一个或多个微针周围的区域中的血液或血液成分中的凝血变化 微针穿透角质层。

    Intraocular lens manufacturing apparatus
    3.
    发明授权
    Intraocular lens manufacturing apparatus 失效
    人工晶状体制造装置

    公开(公告)号:US06732994B2

    公开(公告)日:2004-05-11

    申请号:US10084694

    申请日:2002-02-27

    IPC分类号: B29D1100

    CPC分类号: B29D11/023 Y10S425/808

    摘要: A method of cast molding an intraocular implant from two or more dissimilar materials using disposable molds. The subject cast molding method is particularly useful in the production of intraocular lenses manufactured from dissimilar materials. It is desirable to produce intraocular lenses from dissimilar materials in order to optimize the optical characteristics of the intraocular lens optic portion and to optimize stability and flexibility characteristics of the intraocular lens haptic elements.

    摘要翻译: 使用一次性模具从两种或多种不同材料铸造眼内植入物的方法。 本发明的铸造成型方法在用不同材料制造的眼内透镜的制造中特别有用。 期望从异种材料制造眼内透镜以优化眼内透镜光学部分的光学特性并优化眼内透镜触觉元件的稳定性和柔性特性。

    MEMS interstitial prothrombin time test
    6.
    发明授权
    MEMS interstitial prothrombin time test 失效
    MEMS间质凝血酶原时间检测

    公开(公告)号:US08328720B2

    公开(公告)日:2012-12-11

    申请号:US12189509

    申请日:2008-08-11

    IPC分类号: A61B5/1459

    CPC分类号: A61B5/02035

    摘要: A method of determining a prothrombin time is disclosed. A mediator is applied to a stratum corneum. The stratum corneum is penetrated to allow the mediator to enter a region containing interstitial fluid and interact with at least one capillary, causing blood and/or blood components to leak from the at least one capillary into the region containing interstitial fluid. A characteristic affected by the blood and/or blood components is measured in the region containing interstitial fluid which correlates to the prothrombin time. A system for measuring prothrombin time is also disclosed. The system has a mediator, one or more microneedles, and a processor directly or indirectly coupled to the one or more microneedles and configured to determine a coagulation change in blood or blood components in a region around the one or more microneedles after the one or more microneedles penetrate a stratum corneum.

    摘要翻译: 公开了一种确定凝血酶原时间的方法。 将介体应用于角质层。 穿透角质层以允许介体进入含有组织液的区域并与至少一个毛细管相互作用,导致血液和/或血液成分从至少一个毛细管渗漏到含有间质液的区域中。 在与凝血酶原时间相关的含有间质液的区域中测量受血液和/或血液成分影响的特征。 还公开了一种用于测量凝血酶原时间的系统。 该系统具有介体,一个或多个微针,以及处理器,其直接或间接地耦合到所述一个或多个微针并且被配置为确定在所述一个或多个微针之后的所述一个或多个微针周围的区域中的血液或血液成分中的凝血变化 微针穿透角质层。

    Intraocular lens manufacturing process
    7.
    发明授权
    Intraocular lens manufacturing process 失效
    人工晶状体制造工艺

    公开(公告)号:US06391230B1

    公开(公告)日:2002-05-21

    申请号:US09507151

    申请日:2000-02-18

    IPC分类号: B29D1100

    CPC分类号: B29D11/023 Y10S425/808

    摘要: A method of cast molding an intraocular implant from two or more dissimilar materials using disposable molds. The subject cast molding method is particularly useful in the production of intraocular lenses manufactured from dissimilar materials. It is desirable to produce intraocular lenses from dissimilar materials in order to optimize the optical characteristics of the intraocular lens optic portion and to optimize stability and flexibility characteristics of the intraocular lens haptic elements.

    摘要翻译: 使用一次性模具从两种或多种不同材料铸造眼内植入物的方法。 本发明的铸造成型方法在用不同材料制造的眼内透镜的制造中特别有用。 期望从异种材料制造眼内透镜以优化眼内透镜光学部分的光学特性并优化眼内透镜触觉元件的稳定性和柔性特性。