摘要:
The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.
摘要:
The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.
摘要:
The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase and the activity of PhnC, PhnD, and PhnE is reduced, and enhanced activity of phosphoglycerate dehydrogenase and/or phosphoserine aminotransferase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having these reduced and enhanced properties noted above are also provided herein.
摘要:
The present invention relates to a driving device. The driving device according to the present invention includes a main transistor that supplies a current to a load by using a power supply, an auxiliary transistor that drops a predetermined voltage of the voltage of the power supply and transmits the dropped voltage to the main transistor in a turn-on state, and a bypass switch that transmits the voltage of the power supply to the main transistor when the auxiliary transistor is turned off.
摘要:
Disclosed is an O-phosphoserine sulfhydrylase (OPSS) mutant which has a Mycobacterium smegmatis-derived amino acid sequence corresponding to that of SEQ ID NO: 1 which is devoid of three to seven C-terminal amino acid residues. Also, a nucleic acid molecule encoding the OPSS mutant, an expression vector carrying the nucleic acid molecule, and a transformant transformed with the expression vector are disclosed. In addition, a method is provided for producing cysteine in which O-phospho-L-serine (OPS) is reacted with a sulfide in the presence of the OPSS mutant. The OPSS mutant has improved enzymatic activity and can be applied to the environmentally friendly production of L-cysteine through a simple enzymatic conversion reaction.
摘要翻译:公开了一种O-磷酸丝氨酸二硫氢化酶(OPSS)突变体,其具有对应于SEQ ID NO:1的不含3至7个C末端氨基酸残基的分枝杆菌来源的氨基酸序列。 此外,公开了编码OPSS突变体的核酸分子,携带核酸分子的表达载体和用表达载体转化的转化体。 此外,提供了在OPSS突变体的存在下,使O-磷酸-L-丝氨酸(OPS)与硫化物反应的半胱氨酸的制造方法。 OPSS突变体具有改善的酶活性,可以通过简单的酶转化反应应用于环保生产L-半胱氨酸。
摘要:
Disclosed are an electronic device case provided with a touch sensor unit having an improved adherence structure and a method for manufacturing the same. The electronic device case includes a cover, and a touch sensor unit arranged on a front surface of the cover.
摘要:
The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.
摘要:
The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.
摘要:
Disclosed is an O-phosphoserine sulfhydrylase (OPSS) mutant which has a Mycobacterium smegmatis-derived amino acid sequence corresponding to that of SEQ ID NO: 1 which is devoid of three to seven C-terminal amino acid residues. Also, a nucleic acid molecule encoding the OPSS mutant, an expression vector carrying the nucleic acid molecule, and a transformant transformed with the expression vector are disclosed. In addition, a method is provided for producing cysteine in which O-phospho-L-serine (OPS) is reacted with a sulfide in the presence of the OPSS mutant. The OPSS mutant has improved enzymatic activity and can be applied to the environmentally friendly production of L-cysteine through a simple enzymatic conversion reaction.
摘要翻译:公开了一种O-磷酸丝氨酸二硫氢化酶(OPSS)突变体,其具有对应于SEQ ID NO:1的分枝杆菌衍生的氨基酸序列,其缺少3至7个C-末端氨基酸残基。 此外,公开了编码OPSS突变体的核酸分子,携带核酸分子的表达载体和用表达载体转化的转化体。 此外,提供了在OPSS突变体存在下,使O-磷酸-L-丝氨酸(OPS)与硫化物反应的半胱氨酸的制造方法。 OPSS突变体具有改善的酶活性,可以通过简单的酶转化反应应用于环保生产L-半胱氨酸。
摘要:
The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.