摘要:
New polysubstituted derivatives of naphtalene.These derivatives correspond to the following formula: ##STR1## in which: R.sub.1 to R.sub.4 is H or CH.sub.3R.sub.5 is ##STR2## or (iv) the radical: 2-oxazolinyl m is 0 or 1R.sub.8 is H, alkyl, OR.sub.11, R.sub.11 being H, alkyl or ##STR3## R.sub.13 being alkyl or aryl or R.sub.8 is ##STR4## when m=1, r' and r" representing H, alkyl mono or polyhydroxyalkyl, aryl or a heterocycle when they are taken together, R.sub.9 is H or alkyl, R.sub.10 is H, alkyl and the acetals of the said compounds, ##STR5## --OR.sub.14, R.sub.14 being H, alkyl, mono or polyhydroxyalkyl, aryl or aralkyl a rest of a sugar or represents ##STR6## P being 0, 1, 2, or 3 R.sub.6 represents a hydrogen atom or a lower alkyl radical,R.sub.7 represents H, alkyl, halogen, hydroxyl, sulfydryl, alkoxy, alkylthio, acyloxy, acylthio, acylamino or primary, secondary or tertiary amino and the salts of the said compounds.These compounds find an application in the cosmetic and pharmaceutical fields.
摘要:
A method for eliminating unwanted hairs is provided. The method includes applying an effective amount of a composition including microparticles to the surface of the skin where the hairs are situated and removing the composition remaining on the surface of the skin. The microparticles contain chromophores and a second material different from the chromophores. At least 80% by weight of the microparticles have a diameter of between 3 &mgr;m and 10 &mgr;m. A composition containing a solvent which dissolves the chromophores may then be applied to the surface of the skin. Laser radiation is then applied in one or more shots. The emitted wavelength of the laser radiation is absorbed by the chromophores. The light energy and the emission duration of the laser energy are sufficient to damage and/or kill the cells responsible for the growth of the hair.
摘要:
New 2,6-disubstituted derivatives of naphthalene have the formula ##STR1## wherein n is 1 or 2,R.sub.1 to R.sub.4 are hydrogen or CH.sub.3,R.sub.5 is ##STR2## (iv) 2-oxazolinyl, wherein m is 0 or 1, R.sub.6 is hydrogen, alkyl, OR.sub.9 wherein R.sub.9 is H, alkyl or ##STR3## wherein R.sub.10 is alkyl or aryl, or R.sub.6 is ##STR4## when m=1, r' and r" representing H, alkyl, mono- or poly-hydroxyalkyl, aryl or a heterocycle when taken together, R.sub.7 is H or alkyl, R.sub.8 is H, alkyl and the acetal of said compounds, and the salts of the compounds of formula I. These compounds are usefully employed in the pharmaceutical and cosmetic fields.
摘要:
New polysubstituted derivatives of naphtalene.These derivatives correspond to the following formula: ##STR1## in which: R.sub.1 to R.sub.4 is H or CH.sub.3R.sub.5 is(i) ##STR2## (ii) --C.tbd.N (iii) ##STR3## or (iv) the radical: 2-oxazolinylm is 0 or 1R.sub.8 is H, alkyl, OR.sub.11, R.sub.11 being H, alkyl or ##STR4## R.sub.13 being alkyl or aryl or R.sub.8 is ##STR5## when m=1, r' and r" representing H, alkyl mono or polyhydroxyalkyl, aryl or a heterocycle when they are taken together, R.sub.9 is H or alkyl, R.sub.10 is H, alkyl and the acetals of the said compounds, ##STR6## --OR.sub.14, R.sub.14 being H, alkyl, mono or polyhydroxyalkyl, aryl or aralkyl a rest of a sugar or represents ##STR7## being 0, 1, 2, or 3 R.sub.6 represents a hydrogen atom or a lower alkyl radical,R.sub.7 represents H, alkyl, halogen, hydroxyl, sulfydryl, alkoxy, alkylthio, acyloxy, acylthio, acylamino or primary, secondary or tertiary amino and the salts of the said compounds. These compounds find an application in the cosmetic and pharmaceutical fields.
摘要翻译:萘的新型多取代衍生物。 这些衍生物对应于下式:其中:R 1至R 4为H或CH 3 R 5为(ⅰ)<>)))N(((((((((((the the the the the the the the 基团:2-恶唑啉基m是0或1,R 8是H,烷基,OR 11,R 11是H,烷基或R 13是烷基或芳基,或者R 8是当m = 1时,r'和r“表示 H,烷基单或多羟基烷基,芳基或杂环,当它们一起时,R 9是H或烷基,R 10是H,烷基和所述化合物的缩醛,-OR14,R14是H,烷基,单或 多羟基烷基,芳基或芳烷基,其余的糖或代表0,1,2或3,R 6表示氢原子或低级烷基,R 7表示H,烷基,卤素,羟基,巯基,烷氧基,烷硫基 酰氧基,酰硫基,酰氨基或伯,仲或叔氨基和所述化合物的盐。 这些化合物在化妆品和药物领域中得到应用。
摘要:
Mammalian skin is treated and advantageously smoothed, for example to remove wrinkles, lines, warts and scars therefrom, by topically applying thereto a composition which comprises at least one laser-absorbing chromophore formulated into a physiologically acceptable carrier, diluent or vehicle therefor, and laser-irradiating the skin thus treated with an intensity sufficient to locally convert the light energy into heat energy in the applied composition and advantageously effecting tissue ablation of the surface of the treated skin, said applied composition and the thickness thereof having an absorbance at the emission wavelength of the laser such that the light energy transmitted into the skin generates no undesired irreversible tissue or cell damage.
摘要:
The invention relates to the use of metronidazole, or preferably of a combination of metronidazole and clindamycin, as active principle for the manufacture of pharmaceutical compositions, more particularly dermatological compositions, intended for an anti-inflammatory treatment by the topical route.
摘要:
New polysubstituted derivatives of naphthalene. These derivatives correspond to the following formula: ##STR1## in which: R.sub.1 to R.sub.4 is H or CH.sub.3R.sub.5 is ##STR2## or (iv) the radical: 2-oxazolinyl m is 0 or 1R.sub.8.sbsb.r is H, alkyl, OR.sub.11, R.sub.11 being H, alkyl or ##STR3## R.sub.13 being alkyl or aryl or R.sub.8 is ##STR4## when m=1, r' and r" representing H, alkyl mono or polyhydroxyalkyl, aryl or a heterocycle when they are taken together, R.sub.9 is H or alkyl, R.sub.10 is H, alkyl and the acetals of the said compounds ##STR5## --OR.sub.14, R.sub.14 being H, alkyl, mono or polyhydroxyalkyl, aryl or aralkyl a rest of a sugar or represents ##STR6## being 0, 1, 2 or 3 R.sub.6 represents a hydrogen atom or a lower alkyl radical,R.sub.7 represents H, alkyl, halogen, hydroxyl, sulfydryl, alkoxy, alkylthio, acyloxy, acylthio, acylamino or primary, secondari or tertiary amino and the salts of the said compounds.These compounds find an application in the cosmetic and pharmaceutical fields.