摘要:
The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same.
摘要:
A digital proportional integral loop filter is provided. A first proportional amplification unit multiplies a phase error value by a first proportional loop gain, and a first integral amplification unit multiplies a phase error accumulation value by a first integral loop gain. A second proportional amplification unit multiplies the phase error value by a second proportional loop gain, and a second integral amplification unit multiplies the phase error accumulation value by a second integral loop gain. A first offset value generation unit generates a first offset value by subtracting the second proportional loop gain from the first proportional loop gain and multiplying a resulting value by a phase error average value, and a second offset value generation unit generates a second offset value by subtracting the second integral loop gain from the first integral loop gain and multiplying a resulting value by a phase error accumulation average value.
摘要:
The present invention relates to a pharmaceutical composition for treating alcohol-induced liver injury comprising (4S,5S)-5-fluoromethyl-5-hydroxy-4-({[(5R)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydro-5-isoxazolyl]carbonyl}amino)-dihydrofuran-2-one or pharmaceutically acceptable salt thereof, and a use thereof.
摘要:
The present invention relates to a pyridazinone derivative which can be used as a caspase inhibitor, process for the preparation thereof, and pharmaceutical composition for inhibiting caspase comprising the same.
摘要:
An all digital phase-locked loop (ADPLL) includes: a phase counter accumulating a frequency setting word value and the phase of a digitally controlled oscillator (DCO) clock and detecting a fine phase difference between a reference clock and a retimed clock; a phase detector detecting a digital phase error value compensating for a phase difference between the frequency setting word value and the DCO clock according to the fine phase difference to detect a digital phase error value; a digital loop filter filtering the digital phase error value and controlling PLL operational characteristics; a lock detector generating a lock indication signal according an output of the digital loop filter; a digitally controlled oscillator varying the frequency of the DCO clock according to the output from the digital loop filter; and a retimed clock generator generating the retimed clock by retiming the DCO clock at a low frequency.
摘要:
An all digital phase-locked loop (ADPLL) includes: a phase counter accumulating a frequency setting word value and the phase of a digitally controlled oscillator (DCO) clock and detecting a fine phase difference between a reference clock and a retimed clock; a phase detector detecting a digital phase error value compensating for a phase difference between the frequency setting word value and the DCO clock according to the fine phase difference to detect a digital phase error value; a digital loop filter filtering the digital phase error value and controlling PLL operational characteristics; a lock detector generating a lock indication signal according an output of the digital loop filter; a digitally controlled oscillator varying the frequency of the DCO clock according to the output from the digital loop filter; and a retimed clock generator generating the retimed clock by retiming the DCO clock at a low frequency.
摘要:
The present invention relates to a fused heterocyclic compound having the Formula 1, which is useful as a platelet aggregation inhibitor, a method for preparing the same, and a pharmaceutical composition for inhibiting platelet aggregation comprising the same.
摘要:
A digital proportional integral loop filter is provided. A first proportional amplification unit multiplies a phase error value by a first proportional loop gain, and a first integral amplification unit multiplies a phase error accumulation value by a first integral loop gain. A second proportional amplification unit multiplies the phase error value by a second proportional loop gain, and a second integral amplification unit multiplies the phase error accumulation value by a second integral loop gain. A first offset value generation unit generates a first offset value by subtracting the second proportional loop gain from the first proportional loop gain and multiplying a resulting value by a phase error average value, and a second offset value generation unit generates a second offset value by subtracting the second integral loop gain from the first integral loop gain and multiplying a resulting value by a phase error accumulation average value.
摘要:
The present invention relates to a pyridone derivative which can be used as a caspase inhibitor, process for the preparation thereof, and pharmaceutical composition for inhibiting caspase comprising the same.
摘要:
An apparatus for compensating for an error of a time-to-digital converter (TDC) is disclosed to receive a delay phase from a phase detector including the TDC and a phase error including a TDC error and compensate for the TDC error to have a time resolution higher by N times (N is a natural number). The apparatus includes: a fragmenting and multiplying unit fragmenting the delay phase by N times (N is a natural number) to generate first to (N−1)th fragmented delay phases; an adding unit adding each of the first to the (N−1)th fragmented delay phases to the phase error to generate first to (N−1)th phase errors; and a comparison unit acquiring a phase error compensation value nearest to an actual phase error from the phase error and the first to (N−1)th phase errors.