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公开(公告)号：US08155420B2
公开(公告)日：2012-04-10
申请号：US12470413
申请日：2009-05-21
CPC分类号： G06K9/00147 , G06T7/0002 , G06T11/008 , G06T2200/04 , G06T2207/10101 , G06T2207/30024 , G06T2207/30168 , G06T2211/412
摘要： A system and method for detecting poor quality images in an optical tomography system includes an acquisition apparatus for acquiring a set of pseudo-projection images of an object having a center of mass, where each of the set of pseudo-projection images is acquired at a different angle of view. A reconstruction apparatus is coupled to receive the pseudo-projection images, for reconstruction of the pseudo-projection images into 3D reconstruction images. A quality apparatus is coupled to receive the 3D reconstruction images and operates to detect of selected features that characterize poor quality reconstructions.
摘要翻译： 一种用于在光学断层摄影系统中检测质量差的图像的系统和方法包括：获取装置，用于获取具有质心的物体的一组伪投影图像，其中在一组伪投影图像中获取每个伪投影图像 不同的视角。 耦合重建装置以接收伪投影图像，用于将伪投影图像重建成3D重建图像。 耦合质量装置以接收3D重建图像并操作以检测表征劣质重建的所选特征。
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2.发明申请METHOD FOR IMAGE PROCESSING AND RECONSTRUCTION OF IMAGES FOR OPTICAL TOMOGRAPHY 有权用于光学图像的图像处理和重建图像的方法公开(公告)号：US20080285827A1
公开(公告)日：2008-11-20
申请号：US11750924
申请日：2007-05-18
IPC分类号： G06K9/00
CPC分类号： G06T11/005
摘要： A method for reconstructing three-dimensional (3D) tomographic images. A set of pseudo-projection images of an object is acquired. Error corrections are applied to the set of pseudo-projection images to produce a set of corrected pseudo-projection images. The set of corrected pseudo-projection images are processed to produce (3D) tomographic images.
摘要翻译： 一种重建三维（3D）断层图像的方法。 获取对象的一组伪投影图像。 误差校正被应用于伪投影图像集合以产生一组校正的伪投影图像。 处理该组校正的伪投影图像以产生（3D）断层图像。
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公开(公告)号：US5745601A
公开(公告)日：1998-04-28
申请号：US509181
申请日：1995-07-31
CPC分类号： G06K9/6282 , G06K9/00127
摘要： A classifier measures robustness responsive to object presentation effects and decision boundary effects. A cytological image analysis computer obtains objects of interest and classifies them responsive to a decision tree classifier. The robustness of classification is calculated dynamically as objects are classified responsive to a segmentation robustness and a classification decisiveness measure. The results of the decisiveness measure and the segmentation robustness data are combined to provide enhanced overall classification reliability.
摘要翻译： 分类器测量响应于对象呈现效果和决策边界效应的鲁棒性。 细胞学图像分析计算机获得感兴趣的对象，并对它们进行分类以响应于决策树分类器。 根据分割鲁棒性和分类决定性度量对象进行分类，动态计算分类的鲁棒性。 结合果蔬措施和分割鲁棒性数据的结果，提高整体分类的可靠性。
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公开(公告)号：US08947510B2
公开(公告)日：2015-02-03
申请号：US12999515
申请日：2009-06-08
申请人： Michael G. Meyer , J. Richard Rahn , Anna V. Tourovskaia , Julia Oi Yan Yu , Christy A Lancaster , Thomas Neumann , Mark E. Fauver
发明人： Michael G. Meyer , J. Richard Rahn , Anna V. Tourovskaia , Julia Oi Yan Yu , Christy A Lancaster , Thomas Neumann , Mark E. Fauver
CPC分类号： G06T11/006 , G01N15/1434 , G01N15/1475 , G01N21/49 , G01N21/6458 , G01N2015/1445
摘要： A method for 3D imaging of a biologic object (1) in an optical tomography system where a subcellular structure of a biological object (1) is labeled by introducing at least one nanoparticle-biomarker. The labeled biological object (1) is moved relatively to a microscope objective (62) to present varying angles of view and the labeled biological object (1) is illuminated with radiation having wavelengths between 150 nm and 900 nm. Radiation transmitted through the labeled biological object (1) and the microscope objective (62) within at least one wavelength bands is sensed with a color camera, or with a set of at least four monochrome cameras. A plurality of cross-sectional images of the biological object (1) from the sensed radiation is formed and reconstructed to make a 3D image of the labeled biological object (1).
摘要翻译： 一种用于在其中通过引入至少一种纳米颗粒 - 生物标志物标记生物体（1）的亚细胞结构的光学层析成像系统中的生物物体（1）的3D成像的方法。 标记的生物体（1）相对于显微镜物镜（62）移动以呈现不同的视角，并且用波长在150nm和900nm之间的辐射照射标记的生物物体（1）。 用彩色照相机或一组至少四个单色照相机检测在至少一个波长带内通过标记的生物物体（1）和显微镜物镜（62）发射的辐射。 形成并重构来自感测辐射的生物体（1）的多个横截面图像，以便制成标记的生物体（1）的3D图像。
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公开(公告)号：US07907765B2
公开(公告)日：2011-03-15
申请号：US11532648
申请日：2006-09-18
申请人： Mark E. Fauver , Eric J. Seibel , Michael G. Meyer , Alan C. Nelson , J. Richard Rahn , Thomas Neumann , Roger H. Johnson
发明人： Mark E. Fauver , Eric J. Seibel , Michael G. Meyer , Alan C. Nelson , J. Richard Rahn , Thomas Neumann , Roger H. Johnson
IPC分类号： G06K9/00
CPC分类号： G01N21/4795 , G01N15/147 , G01N15/1475
摘要： An optical tomography system for imaging an object of interest including a light source for illuminating the object of interest with a plurality of radiation beams. The object of interest is held within an object containing tube such that it is illuminated by the plurality of radiation beams to produce emerging radiation from the object containing tube, a detector array is located to receive the emerging radiation and produce imaging data used by a mechanism for tracking the object of interest.
摘要翻译： 一种光学断层摄影系统，用于对感兴趣的物体成像，包括用多个辐射束照射感兴趣物体的光源。 感兴趣的物体被保持在物体容纳管内，使得其被多个辐射束照射以产生来自物体容纳管的出射辐射，检测器阵列被定位成接收新出现的辐射并产生由机构使用的成像数据 用于跟踪感兴趣的对象。
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公开(公告)号：US20100322494A1
公开(公告)日：2010-12-23
申请号：US11532648
申请日：2006-09-18
申请人： Mark E. Fauver , Eric J. Seibel , Michael G. Meyer , Alan C. Nelson , J. Richard Rahn , Thomas Neumann , Roger H. Johnson
发明人： Mark E. Fauver , Eric J. Seibel , Michael G. Meyer , Alan C. Nelson , J. Richard Rahn , Thomas Neumann , Roger H. Johnson
IPC分类号： G06K9/00
CPC分类号： G01N21/4795 , G01N15/147 , G01N15/1475
摘要： An optical tomography system for imaging an object of interest including a light source for illuminating the object of interest with a plurality of radiation beams. The object of interest is held within an object containing tube such that it is illuminated by the plurality of radiation beams to produce emerging radiation from the object containing tube, a detector array is located to receive the emerging radiation and produce imaging data used by a mechanism for tracking the object of interest.
摘要翻译： 一种光学断层摄影系统，用于对感兴趣的物体成像，包括用多个辐射束照射感兴趣物体的光源。 感兴趣的物体被保持在物体容纳管内，使得其被多个辐射束照射以产生来自物体容纳管的出射辐射，检测器阵列被定位成接收新出现的辐射并产生由机构使用的成像数据 用于跟踪感兴趣的对象。
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7.发明授权Method for image processing and reconstruction of images for optical tomography 有权用于光学层析成像的图像处理和重建方法公开(公告)号：US07835561B2
公开(公告)日：2010-11-16
申请号：US11750924
申请日：2007-05-18
CPC分类号： G06T11/005
摘要： A method for reconstructing three-dimensional (3D) tomographic images. A set of pseudo-projection images of an object is acquired. Error corrections are applied to the set of pseudo-projection images to produce a set of corrected pseudo-projection images. The set of corrected pseudo-projection images are processed to produce (3D) tomographic images.
摘要翻译： 一种重建三维（3D）断层图像的方法。 获取对象的一组伪投影图像。 误差校正被应用于伪投影图像集合以产生一组校正的伪投影图像。 处理该组校正的伪投影图像以产生（3D）断层图像。
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公开(公告)号：US6134354A
公开(公告)日：2000-10-17
申请号：US121012
申请日：1998-07-22
申请人： Shih-Jong J. Lee , Paul S. Wilhelm , Wendy R. Bannister , Chih-Chau L. Kuan , Seho Oh , Michael G. Meyer
发明人： Shih-Jong J. Lee , Paul S. Wilhelm , Wendy R. Bannister , Chih-Chau L. Kuan , Seho Oh , Michael G. Meyer
CPC分类号： G06K9/00127 , G01N15/1475 , G01N2015/1497
摘要： A free-lying cell classifier. An automated microscope system comprising a computer and high speed processing field of view processors identifies free-lying cells. An image of a biological specimen is obtained and the image is segmented to create a set of binary masks. The binary masks are used by a feature calculator to compute the features that characterize objects of interest including free-lying cells, artifacts and other biological objects. The objects are classified to identify their type, their normality or abnormality or their identification as an artifact. The results are summarized and reported. A stain evaluation of the slide is performed as well as a typicality evaluation. The robustness of the measurement is also quantified as a classification confidence value. The free-lying cell evaluation is used by an automated cytology system to classify a biological specimen slide.
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公开(公告)号：US5828776A
公开(公告)日：1998-10-27
申请号：US678124
申请日：1996-07-11
CPC分类号： G06K9/00127 , G06K9/685
摘要： A biological specimen classification strategy employs identification and integration of multiple cell patterns. An automated microscope acquires an image of a biological specimen such as a Pap smear and provides an image output to biological classifiers. The classifiers independently detect and classify a number of specimen types and provide classifications to an output field of view integrator. The integrator integrates the classifications. The integrated output then determines whether the classifiers should be reapplied to the image.
摘要翻译： 生物样本分类策略采用多重细胞模式的识别和整合。 自动显微镜获取诸如巴氏涂片的生物样本的图像，并向生物分类器提供图像输出。 分类器独立地检测和分类多个样本类型，并为输出视场积分器提供分类。 集成商整合分类。 然后，集成输出确定分类器是否应重新应用于映像。
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公开(公告)号：US08090183B2
公开(公告)日：2012-01-03
申请号：US12403231
申请日：2009-03-12
IPC分类号： G06K9/18
CPC分类号： G01N15/1475 , G01N15/147 , G06T5/002 , G06T7/136 , G06T11/005 , G06T2207/10072 , G06T2207/30024 , H04N5/365
摘要： Correcting pattern noise projection images includes acquiring a set of projection images with an optical tomography system including a processor, where each of the set of projection images is acquired at a different angle of view. A threshold is applied to each projection image produce a set of threshold images. Each threshold image may optionally be dilated to produce a set of dilated images that are summed to form an ensemble image. Each of the dilated images is processed to produce a set of binary images. The set of binary images are summed to form an ensemble mask. The ensemble image is divided by the ensemble mask to yield a background pattern noise image. Each projection image is multiplied by a scaling factor and divided by the background pattern noise to produce a quotient image that is filtered to produce a noise corrected projection image.
摘要翻译： 校正图案噪声投影图像包括使用包括处理器的光学层析成像系统获取一组投影图像，其中以不同的视角获取投影图像集合中的每一个。 对每个投影图像应用阈值产生一组阈值图像。 每个阈值图像可以可选地被扩展以产生一组被累加以形成整体图像的扩张图像。 每个扩张的图像被处理以产生一组二进制图像。 将二进制图像的集合相加以形成集合掩码。 整体图像由合成掩模划分以产生背景图案噪声图像。 将每个投影图像乘以缩放因子并除以背景图案噪声，以产生被滤波以产生噪声校正投影图像的商图像。
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