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公开(公告)号:US20240247049A1
公开(公告)日:2024-07-25
申请号:US18443512
申请日:2024-02-16
IPC分类号: C07K14/72 , A61K31/7088 , A61K35/76 , A61K38/00 , A61K48/00 , A61P27/02 , C07K14/195 , C07K14/705 , C07K19/00 , C12N15/09 , C12N15/86
CPC分类号: C07K14/723 , A61K31/7088 , A61K35/76 , A61K38/00 , A61K48/00 , A61P27/02 , C07K14/195 , C12N15/09 , C12N15/86 , C07K14/705 , C07K19/00 , C12N2750/14143
摘要: The purpose of the present invention is to provide an agent for restoring a visual function or an agent for preventing the deterioration in a visual function, which has an excellent visual function restoring ability. The agent for regenerating a visual function or the agent for preventing the deterioration in a visual function according to the present invention contains, as an active ingredient, a chimeric protein having both an amino acid sequence for a microorganism-origin ion-transporting receptor rhodopsin and an amino acid sequence for an animal-origin G-protein-coupled receptor rhodopsin. The chimeric protein is preferably one in which an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the amino acid sequence for the microorganism-origin ion-transporting receptor rhodopsin is substituted by an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the G-protein-coupled receptor rhodopsin.
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公开(公告)号:US12030917B2
公开(公告)日:2024-07-09
申请号:US17276399
申请日:2019-09-13
IPC分类号: C07K14/405 , A61K38/00 , A61P27/02 , G01N33/68
CPC分类号: C07K14/405 , A61P27/02 , G01N33/68 , A61K38/00 , G01N2333/405
摘要: An excellent photosensitivity is exhibited by a protein including, at a position or positions corresponding to one or two or more positions selected from the group made of the following (1) to (3) in a first amino acid sequence represented by SEQ ID NO: 1: (1) positions 39, 94, 98, 102, 110, 113, 114, 162, 224, 225, 230, 231, and 235, (2) positions 53, 61, 68, 74, 76, 80, 130, 137, 194, 195, 198, 200, 204, 205, 209, 210, 253, and 254, and (3) positions 46, 83, 84, 87, 90, 91, 116, 117, 120, 124, 139, 142, 143, 146, 173, 214, 216, 217, 238, 242, and 245, an amino acid residue different from that in the first amino acid sequence, and that has channel activity.
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公开(公告)号:US20240174794A1
公开(公告)日:2024-05-30
申请号:US18284723
申请日:2022-03-25
发明人: Shoko UCHIYAMA , Hideki TANAKA , Akinori TAKASU
IPC分类号: C08G63/183 , C08G63/78
CPC分类号: C08G63/183 , C08G63/78 , C08G2150/00 , C08G2170/00
摘要: An object of the present invention is to provide a polyester resin that has a high degree of freedom in design and that can have excellent biodegradability even with an increased molecular weight. A polyester of the present invention contains a hydroxy group-containing dicarboxylic acid component and a diol component (excluding a hydroxy group-containing dicarboxylic acid component) as copolymerization components, wherein more than 50 mol % of an aliphatic diol component is contained in 100 mol % of the diol component, the polyester has a number average molecular weight of 3000 or higher, and the polyester has a total hydroxyl value of 1000 eq/ton or higher.
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公开(公告)号:US20240117113A1
公开(公告)日:2024-04-11
申请号:US18510812
申请日:2023-11-16
发明人: Takashi OKAZOE , Masahito SUZUKI
IPC分类号: C08G64/04
CPC分类号: C08G64/04
摘要: A method for producing a polycarbonate, including reacting a dihydroxy component with a fluorine-containing carbonate component in a presence of a condensation catalyst to obtain a prepolymer, and heating the prepolymer at a temperature lower than a melting temperature of the prepolymer and subjecting the prepolymer to a solid state polymerization while discharging a by-produced fluorine-containing alcohol outside a system,
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公开(公告)号:US11855254B2
公开(公告)日:2023-12-26
申请号:US16923808
申请日:2020-07-08
发明人: Reona Miyazaki , Toshihiro Yoshida , Satoshi Ozaki , Yosuke Sato , Yuji Katsuda
IPC分类号: H01M10/0562 , C01D15/02 , C01D15/06
CPC分类号: H01M10/0562 , C01D15/02 , C01D15/06 , C01P2006/10 , C01P2006/40 , H01M2300/0071
摘要: Provided is a solid electrolyte which contains a composition expressed by 3LiOH·Li2SO4. The solid electrolyte has a lithium ion conductivity of 0.1×10−6 S/cm or more at 25° C. and an activation energy of 0.6 eV or more.
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公开(公告)号:US20230261604A1
公开(公告)日:2023-08-17
申请号:US18010575
申请日:2021-03-26
发明人: Subrata SAHA , Hiroki IWAI , Takashi KOSAKA , Hiroaki MATSUMORI
IPC分类号: H02P27/08 , H02P29/028
CPC分类号: H02P27/085 , H02P29/028
摘要: In a first control state, it is determined which one of a first failure pattern (FP1) and a second failure pattern (FP2) is a failure pattern (FT), and in a second control state, it is determined which one of a first lower-stage-side failure pattern (LF1) and a second lower-stage-side failure pattern (LF2) is a lower-stage-side failure pattern (LF), and it is determined which one of a set of upper-stage-side arms of a first inverter (11), a set of lower-stage-side arms of the first inverter (12), a set of upper-stage-side arms of a second inverter (12), and a set of lower-stage-side arms of the second inverter (12) is failure-side arms, based on a result of the determination in the first control state and a result of the determination in the second control state.
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公开(公告)号:US20230028358A1
公开(公告)日:2023-01-26
申请号:US17782713
申请日:2020-09-29
发明人: Subrata SAHA , Hiroki IWAI , Takashi KOSAKA , Hiroak MATSUMORI , Naoto SAITO , Yoshinobu ITO , Isao FUJIWARA
IPC分类号: H02P27/08 , H02K11/33 , H02M7/5395 , H02P6/08
摘要: Two inverters (10) provided at respective both ends of open-end windings (8) are appropriately controlled. As control regions (R) of a rotating electrical machine (80), a first speed region (VR1) and a second speed region (VR2) in which the rotational speed of the rotating electrical machine (80) is higher than in the first speed region (VR1) for the same torque are set, and in the second speed region (VR2), a rotating electrical machine control device (1) controls both inverters (10), a first inverter (11) and a second inverter (12), by mixed pulse width modulation control in which control is performed such that a plurality of pulses with different patterns are outputted during a first period (T1) which is a half cycle of electrical angle, and an inactive state continues during a second period (T2) which is the other half cycle.
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公开(公告)号:US20230028189A1
公开(公告)日:2023-01-26
申请号:US17956019
申请日:2022-09-29
摘要: A rotary electric machine includes a rotor, and a stator facing the rotor with a predetermined gap interposed between the rotor and stator. The stator has a stator core formed in a substantially circular annular shape and provided with an armature slot and a field slot alternately arranged in a circumferential direction, an armature winding housed in the armature slot, and a field winding and a first field magnet housed in the field slot. The armature winding generates a rotating magnetic field to rotate the rotor by being supplied with an alternating current armature current. The field winding generates a field flux by being supplied with a direct current field current. The first field magnet changes a magnetic force by the field flux.
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公开(公告)号:US11440147B2
公开(公告)日:2022-09-13
申请号:US16800261
申请日:2020-02-25
申请人: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM , NAGOYA INSTITUTE OF TECHNOLOGY
发明人: Eiji Shamoto , Fumihiro Itoigawa
IPC分类号: B23D63/00 , B23D63/08 , B23D65/00 , B23K26/00 , B23K26/082 , B23K26/38 , B23K26/50 , B23P15/24 , B23B27/14
摘要: A controller performs a first process of scanning a cylindrical irradiation region including a focused spot of laser light emitted from a laser light emitter to machine a flank face side of a workpiece to manufacture a cutting tool having a plurality of cutting edges arranged in line. In the first process, the controller scans the cylindrical irradiation region along a scanning path that has periodicity and changes a machining depth to form the plurality of cutting edges. The controller further performs a second process of scanning the cylindrical irradiation region including the focused spot of the laser light emitted in a direction different from an irradiation direction of the laser light in the first process to machine a rake face side of the workpiece.
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公开(公告)号:US10953351B2
公开(公告)日:2021-03-23
申请号:US16098828
申请日:2017-04-27
发明人: Shuichi Iwata , Katsuaki Odagi , Yoshihisa Suzuki
IPC分类号: B01D19/00
摘要: A continuous bubble removal method includes: preparing a main container, a basic pressurization container that connects to the main container and holds a basic operating liquid, and a basic movable portion that is displaceably attached to the basic pressurization container; flowing target liquid through the main container, the liquid including a bubble; and iteratively decreasing and increasing a volume of the bubble by iteratively pressurizing and depressurizing the target liquid from a region via the basic operating liquid by displacing, in a reciprocating manner, the basic movable portion, the region being surrounded by a basic connecting portion of the basic pressurization container that is closer to the main container than the basic supporting portion, wherein an opening area of the basic supporting portion is larger than an opening area of the basic connecting portion.
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