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    Method for fabricating foam scaffolds to culture cells
    1.
    发明授权
    Method for fabricating foam scaffolds to culture cells 有权
    制造泡沫支架培养细胞的方法

    公开(公告)号：US08513014B2

    公开(公告)日：2013-08-20

    申请号：US12582575

    申请日：2009-10-20

    Applicant: Keng-Hui Lin ,  Narayan Mishra ,  Yen-Liang Liu ,  Chen-Chie Wang

    Inventor： Keng-Hui Lin ,  Narayan Mishra ,  Yen-Liang Liu ,  Chen-Chie Wang

    IPC: C12N5/00 ,  C12N5/07 ,  C12M1/00

    CPC classification number: C12N5/0655 ,  B29C44/00 ,  C12M25/14 ,  C12N5/0068 ,  C12N2533/74

    Abstract: Methods and apparatuses for using microfluidics to generate bubbles and using the generated bubbles to construct scaffolds and cell-holding structures for culturing biological samples or analytes. In one implementation, a scaffold for growing cells is provided to include a matrix of interconnected cavities formed from mixing a gas and a liquid containing a cross linkable material to produce a matrix of gas bubbles of substantially the same size and cross linking the cross linkable material to form a structure in which cells are grown. In another implementation, a scaffold apparatus for growing cells includes a ball of a cross linked material forming an exterior shell that encloses to form a hollow interior inside the ball and biological samples embedded in the external shell.

    Abstract translation: 使用微流体产生气泡并使用生成的气泡构建用于培养生物样品或分析物的支架和细胞保持结构的方法和装置。 在一个实施方案中，提供了用于生长细胞的支架，以包括通过混合气体和含有可交联材料的液体形成的互连腔的基质，以产生基本上相同尺寸的气泡基质并交联可交联材料 以形成细胞生长的结构。 在另一实施方案中，用于生长细胞的支架装置包括形成外壳的交联材料球，所述外壳包围以形成球内的中空内部并嵌入外壳中的生物样品。

    System and Method for Providing Enterprise Information Technology Lifecycle Tools Synchronization Platform
    2.
    发明申请
    System and Method for Providing Enterprise Information Technology Lifecycle Tools Synchronization Platform 有权
    提供企业信息技术生命周期工具同步平台的系统和方法

    公开(公告)号：US20130211569A1

    公开(公告)日：2013-08-15

    申请号：US13752984

    申请日：2013-01-29

    Applicant: Suresh Cherusseri ,  Satya Narayan Mishra

    Inventor： Suresh Cherusseri ,  Satya Narayan Mishra

    IPC: G05B15/02

    CPC classification number: G06Q10/06 ,  G06F17/00

    Abstract: The present invention relates to a system and method for integrating and assembling plurality of service delivery tools created on disparate technologies on a product assembly platform. Further, the invention provides a reference architecture and method for orchestrating the assembled plurality of service delivery tools and monitoring the lifecycle activities of the plurality of service delivery tools.

    Abstract translation: 本发明涉及一种用于集成和组装在产品组装平台上以不同技术创建的多个服务递送工具的系统和方法。 此外，本发明提供了用于协调组装的多个服务递送工具并监视多个服务递送工具的生命周期活动的参考架构和方法。

    Fabricating Scaffolds and Other Cell-Growth Structures Using Microfluidics to Culture Biological Samples
    5.
    发明申请
    Fabricating Scaffolds and Other Cell-Growth Structures Using Microfluidics to Culture Biological Samples 有权
    使用微流体培养生物样品制备支架和其他细胞生长结构

    公开(公告)号：US20110091972A1

    公开(公告)日：2011-04-21

    申请号：US12582575

    申请日：2009-10-20

    Applicant: Keng-Hui Lin ,  Narayan Mishra ,  Yen-Liang Liu ,  Chen-chie Wang

    Inventor： Keng-Hui Lin ,  Narayan Mishra ,  Yen-Liang Liu ,  Chen-chie Wang

    IPC: C12N5/00 ,  B29C44/36

    CPC classification number: C12N5/0655 ,  B29C44/00 ,  C12M25/14 ,  C12N5/0068 ,  C12N2533/74

    Abstract: Methods and apparatuses for using microfluidics to generate bubbles and using the generated bubbles to construct scaffolds and cell-holding structures for culturing biological samples or analytes. In one implementation, a scaffold for growing cells is provided to include a matrix of interconnected cavities formed from mixing a gas and a liquid containing a cross linkable material to produce a matrix of gas bubbles of substantially the same size and cross linking the cross linkable material to form a structure in which cells are grown. In another implementation, a scaffold apparatus for growing cells includes a ball of a cross linked material forming an exterior shell that encloses to form a hollow interior inside the ball and biological samples embedded in the external shell.

    Abstract translation: 使用微流体产生气泡并使用生成的气泡构建用于培养生物样品或分析物的支架和细胞保持结构的方法和装置。 在一个实施方案中，提供了用于生长细胞的支架，以包括通过混合气体和含有可交联材料的液体形成的互连腔的基质，以产生基本上相同尺寸的气泡基质并交联可交联材料 以形成细胞生长的结构。 在另一实施方案中，用于生长细胞的支架装置包括形成外壳的交联材料球，所述外壳包围以形成球内的中空内部并嵌入外壳中的生物样品。

    Integrator ramp generator with DAC and switched capacitors
    7.
    发明授权
    Integrator ramp generator with DAC and switched capacitors 有权
    具有DAC和开关电容器的积分器斜坡发生器

    公开(公告)号：US08614639B1

    公开(公告)日：2013-12-24

    申请号：US13593520

    申请日：2012-08-24

    Applicant: Ping Hung Yin ,  Satya Narayan Mishra ,  Amit Mittra

    Inventor： Ping Hung Yin ,  Satya Narayan Mishra ,  Amit Mittra

    IPC: H03M1/56

    CPC classification number: H03M1/56

    Abstract: A ramp generator includes a digital-to-analog converter (DAC), a sampling capacitor, an integrator circuit, a polarity reversing switch selectively coupling first and second outputs of the DAC to a first side of the sampling capacitor, a first switch coupling a second side of the sampling capacitor to a reference voltage source, and a second switch coupling the second side of the sampling capacitor to an input of the integrator circuit.

    Abstract translation: 斜坡发生器包括数模转换器（DAC），采样电容器，积分器电路，选择性地将DAC的第一和第二输出端耦合到采样电容器的第一侧的极性反转开关，第一开关耦合 采样电容器的第二侧到参考电压源，以及将采​​样电容器的第二侧耦合到积分器电路的输入的第二开关。

    Auditory front end customization
    8.
    发明授权
    Auditory front end customization 有权
    听觉前端定制

    公开(公告)号：US08503685B2

    公开(公告)日：2013-08-06

    申请号：US12953159

    申请日：2010-11-23

    Applicant: Abhijit Kulkarni ,  Lakshimi Narayan Mishra ,  Michael A. Faltys

    Inventor： Abhijit Kulkarni ,  Lakshimi Narayan Mishra ,  Michael A. Faltys

    IPC: H04R25/00 ,  H04B15/00 ,  H03B29/00 ,  A61N1/00

    CPC classification number: H04R25/70 ,  A61N1/36036 ,  G06F19/00 ,  H04R1/406 ,  H04R25/606 ,  H04R2225/021 ,  H04R2225/67 ,  H04R2430/20

    Abstract: A method and system for implementing an acoustical front end customization are disclosed. The customization is implemented to optimize the sound level for each individual cochlear implant user. A known audio signal is generated using a sound source and captured by a microphone system. The captured sound signal is sampled at one or more locations along the signal processing pathway, and a spectrum is determined for the sampled signal and the known signal. A ratio of the two spectrums is related to the undesired transformation of the sampled signal, and a digital filter is designed based on the ratio to filter out the undesired transformation.

    Abstract translation: 公开了一种用于实现声学前端定制的方法和系统。 实施定制以优化每个单独的人工耳蜗使用者的声级。 使用声源产生已知的音频信号，并由麦克风系统捕获。 捕获的声音信号在沿着信号处理路径的一个或多个位置被采样，并且对采样信号和已知信号确定频谱。 两个频谱的比率与采样信号的不期望的变换有关，并且基于该比率设计数字滤波器以滤除不希望的变换。

    Auditory Front End Customization
    9.
    发明申请
    Auditory Front End Customization 有权
    听觉前端定制

    公开(公告)号：US20110069853A1

    公开(公告)日：2011-03-24

    申请号：US12953159

    申请日：2010-11-23

    Applicant: Abhijit Kulkarni ,  Lakshimi Narayan Mishra ,  Michael A. Faltys

    Inventor： Abhijit Kulkarni ,  Lakshimi Narayan Mishra ,  Michael A. Faltys

    IPC: H04R25/00

    CPC classification number: H04R25/70 ,  A61N1/36036 ,  G06F19/00 ,  H04R1/406 ,  H04R25/606 ,  H04R2225/021 ,  H04R2225/67 ,  H04R2430/20

    Abstract: A method and system for implementing an acoustical front end customization are disclosed. The customization is implemented to optimize the sound level for each individual cochlear implant user. A known audio signal is generated using a sound source and captured by a microphone system. The captured sound signal is sampled at one or more locations along the signal processing pathway, and a spectrum is determined for the sampled signal and the known signal. A ratio of the two spectrums is related to the undesired transformation of the sampled signal, and a digital filter is designed based on the ratio to filter out the undesired transformation.

    Abstract translation: 公开了一种用于实现声学前端定制的方法和系统。 实施定制以优化每个单独的人工耳蜗使用者的声级。 使用声源产生已知的音频信号，并由麦克风系统捕获。 捕获的声音信号在沿着信号处理路径的一个或多个位置被采样，并且对采样信号和已知信号确定频谱。 两个频谱的比率与采样信号的不期望的变换有关，并且基于该比率设计数字滤波器以滤除不希望的变换。

    System and method for fitting a cochlear implant sound processor using alternative signals
    10.
    发明授权
    System and method for fitting a cochlear implant sound processor using alternative signals 有权
    使用替代信号拟合人工耳蜗声音处理器的系统和方法

    公开(公告)号：US07496406B1

    公开(公告)日：2009-02-24

    申请号：US10651653

    申请日：2003-08-29

    Applicant: Philip A. Segel ,  Edward H. Overstreet ,  Tracey L. Kruger ,  Lakshmi Narayan Mishra

    Inventor： Philip A. Segel ,  Edward H. Overstreet ,  Tracey L. Kruger ,  Lakshmi Narayan Mishra

    IPC: A61N1/04

    CPC classification number: A61N1/36036

    Abstract: Alternative stimuli, i.e., stimuli other than the constant amplitude stimuli used in prior fitting schemes, is used to set the parameters of a cochlear implant system. The use of such alternative stimuli allows the entire fitting process to be completed in a very short time period, and generally eliminates the need for secondary adjustments. In one preferred embodiment, the alternative stimuli comprise white noise that is internally generated within the speech processor.

    Abstract translation: 使用替代刺激，即除了先前拟合方案中使用的恒定振幅刺激之外的刺激，以设置耳蜗植入物系统的参数。 这种替代刺激的使用允许整个装配过程在非常短的时间内完成，并且通常消除了对二次调节的需要。 在一个优选实施例中，替代刺激包括在语音处理器内部产生的白噪声。

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