公开(公告)号：US09286937B2

公开(公告)日：2016-03-15

申请号：US13591353

申请日：2012-08-22

申请人： Ali Mostoufi ,  Samuel Sutch ,  Pamela Kramer

发明人： Ali Mostoufi ,  Samuel Sutch ,  Pamela Kramer

IPC分类号： H04N5/76 ,  G11B27/02 ,  G11B27/031 ,  G11B27/32 ,  H04N21/262 ,  H04N21/2743 ,  H04N21/4223 ,  H04N21/4788 ,  H04N21/854

CPC分类号： G11B27/02 ,  G11B27/031 ,  G11B27/322 ,  H04N21/26258 ,  H04N21/2743 ,  H04N21/4223 ,  H04N21/4788 ,  H04N21/854

摘要： The invention can be a computerized method for creating a composite media program. The method can include receiving from a first user over a network at least a first media segment, wherein the first media segment includes a first plurality of media frames. The method can also include receiving from a second user over the network at least a second media segment, wherein the second media segment includes a second plurality of media frames. Finally, the method includes automatically combining at least the first media segment and the second media segment into the composite media program including a series of media segments, wherein the composite media program is available for viewing by at least a set of members of a social network.

摘要翻译： 本发明可以是用于创建复合媒体节目的计算机化方法。 该方法可以包括通过网络从第一用户接收至少第一媒体段，其中第一媒体段包括第一多个媒体帧。 该方法还可以包括通过网络从第二用户接收至少第二媒体段，其中第二媒体段包括第二多个媒体帧。 最后，该方法包括将至少第一媒体段和第二媒体段自动组合到包括一系列媒体段的复合媒体节目中，其中复合媒体节目可由至少一组社交网络的成员查看 。

公开(公告)号：US20080058919A1

公开(公告)日：2008-03-06

申请号：US11888500

申请日：2007-07-31

申请人： Pamela Kramer-Brown ,  David Gale ,  Vincent Gueriguian ,  Yunbing Wang

发明人： Pamela Kramer-Brown ,  David Gale ,  Vincent Gueriguian ,  Yunbing Wang

IPC分类号： A61F2/06

CPC分类号： A61L31/18 ,  A61F2/82 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2210/0004 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0097 ,  A61L31/08 ,  A61L31/128 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/00 ,  A61L2300/606 ,  C08L67/04

摘要： Various embodiments of stents with a polymeric body with radiopaque metallic particles incorporated in the stent body.

摘要翻译： 具有聚合体的支架的各种实施例，其具有结合在支架主体中的不透射线金属颗粒。

公开(公告)号：US20080306584A1

公开(公告)日：2008-12-11

申请号：US11810518

申请日：2007-06-05

申请人： Pamela Kramer-Brown

发明人： Pamela Kramer-Brown

IPC分类号： A61F2/06

CPC分类号： A61L31/10 ,  A61L31/088 ,  A61L31/127 ,  A61L31/14 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/604 ,  A61L2300/608 ,  A61L2300/624 ,  A61L2400/12

摘要： Implantable medical devices adapted to erodibly release delivery media for local and regional treatment are disclosed.

摘要翻译： 公开了适用于本地和区域处理的适用于可释放释放输送介质的可植入医疗装置。

公开(公告)号：US20140056574A1

公开(公告)日：2014-02-27

申请号：US13591353

申请日：2012-08-22

申请人： Ali MOSTOUFI ,  Samuel SUTCH ,  Pamela KRAMER

发明人： Ali MOSTOUFI ,  Samuel SUTCH ,  Pamela KRAMER

IPC分类号： G11B27/02

CPC分类号： G11B27/02 ,  G11B27/031 ,  G11B27/322 ,  H04N21/26258 ,  H04N21/2743 ,  H04N21/4223 ,  H04N21/4788 ,  H04N21/854

摘要： The invention can be a computerized method for creating a composite media program. The method can include receiving from a first user over a network at least a first media segment, wherein the first media segment includes a first plurality of media frames. The method can also include receiving from a second user over the network at least a second media segment, wherein the second media segment includes a second plurality of media frames. Finally, the method includes automatically combining at least the first media segment and the second media segment into the composite media program including a series of media segments, wherein the composite media program is available for viewing by at least a set of members of a social network.

摘要翻译： 本发明可以是用于创建复合媒体节目的计算机化方法。 该方法可以包括通过网络从第一用户接收至少第一媒体段，其中第一媒体段包括第一多个媒体帧。 该方法还可以包括通过网络从第二用户接收至少第二媒体段，其中第二媒体段包括第二多个媒体帧。 最后，该方法包括将至少第一媒体段和第二媒体段自动组合到包括一系列媒体段的复合媒体节目中，其中复合媒体节目可由至少一组社交网络的成员查看 。

公开(公告)号：US20070255387A1

公开(公告)日：2007-11-01

申请号：US11771889

申请日：2007-06-29

申请人： PAMELA KRAMER ,  JOHN MORRIS

发明人： PAMELA KRAMER ,  JOHN MORRIS

IPC分类号： A61F2/06 ,  B21D31/00

CPC分类号： A61L29/02 ,  A61F2/01 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/075 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61L31/022 ,  A61L31/14

摘要： Medical devices are manufactured from fine grained materials, processed from of a variety of metals and alloys, such as stainless steel, cobalt-chromium and nickel-titanium alloys. A fine grained metal or alloy is formed from a specimen rapidly heated to its recrystallization temperature, and then subjected to high temperature, multi-axial deformation, for example, by heavy cross-forging or swaging. The deformed specimen may be cooled and reheated to a second recrystallization temperature. The metal or alloy in the specimen is then allowed to recrystallize, such that the grain size is controlled by quenching the specimen to room temperature. A desired medical device is then configured from the fine grained material. Decreasing the average grain size of a substrate material and increasing the number of grains across a thickness of a strut or similar component of the medical device increases the strength of the device and imparts other beneficial properties into the device.

摘要翻译： 医疗器械由细粒材料制成，由各种金属和合金（如不锈钢，钴铬和镍钛合金）加工而成。 由快速加热到其再结晶温度的试样形成细粒状金属或合金，然后例如通过重交叉锻造或模锻进行高温多轴变形。 变形的试样可以冷却并再次加热至第二再结晶温度。 然后将样品中的金属或合金重结晶，使得通过将样品淬火至室温来控制晶粒尺寸。 然后从细粒材料配置期望的医疗装置。 降低衬底材料的平均晶粒尺寸并增加穿过医疗装置的支柱或类似部件的厚度的晶粒数增加了装置的强度并赋予装置其它有益特性。

公开(公告)号：US20070036905A1

公开(公告)日：2007-02-15

申请号：US11582703

申请日：2006-10-17

申请人： Pamela Kramer

发明人： Pamela Kramer

IPC分类号： A61L33/00 ,  B05D3/00 ,  B05D7/00 ,  B05C19/00 ,  B05C5/00

CPC分类号： A61L27/306 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/106 ,  A61L29/16 ,  A61L31/082 ,  A61L31/088 ,  A61L31/10 ,  A61L31/14 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/606 ,  A61L2420/02 ,  B05B7/0006 ,  B05B7/203 ,  B05B7/205 ,  B05B7/224 ,  B05B7/226 ,  C23C4/12 ,  C23C24/04 ,  C23C28/00 ,  C23C28/028 ,  C23C28/321 ,  C23C28/322 ,  C23C28/34 ,  C23C28/3455 ,  C23C28/36 ,  Y10T428/12021 ,  Y10T428/12292 ,  Y10T428/12299 ,  Y10T428/13 ,  Y10T428/1376 ,  Y10T428/139

摘要： Thermal spray processing and cold spray processing are utilized to manufacture porous starting materials (such as tube stock, wire and substrate sheets) from biocompatible metals, metal alloys, ceramics and polymers that may be further processed into porous medical devices, such as stents. The spray processes are also used to form porous coatings on consolidated biocompatible medical devices. The porous substrates and coatings may be used as a reservoir to hold a drug or therapeutic agent for elution in the body. The spray-formed porous substrates and coatings may be functionally graded to allow direct control of drug elution without an additional polymer topcoat. The spray processes are also used to apply the drug or agent to the porous substrate or coating when drug or agent is robust enough to withstand the temperatures and velocities of the spray process with minimal degradation.

摘要翻译： 使用热喷涂处理和冷喷涂处理从生物相容性金属，金属合金，陶瓷和聚合物制造多孔起始材料（例如管材料，线材和基材片），其可以进一步加工成多孔医疗装置，例如支架。 喷雾方法也用于在固体生物相容性医疗装置上形成多孔涂层。 多孔基材和涂层可以用作储存器以容纳用于体内洗脱的药物或治疗剂。 喷雾形成的多孔基材和涂层可以在功能上分级，以允许药物洗脱的直接控制，而不需要额外的聚合物面漆。 当药物或试剂足够坚固以承受喷雾过程的温度和速度并且具有最小降解时，喷雾方法也用于将药物或试剂施用于多孔基质或涂层。

公开(公告)号：US20060271168A1

公开(公告)日：2006-11-30

申请号：US11438925

申请日：2006-05-22

申请人： Klaus Kleine ,  Pamela Kramer-Brown

发明人： Klaus Kleine ,  Pamela Kramer-Brown

IPC分类号： A61F2/06

CPC分类号： A61L31/022 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2230/0054 ,  A61F2250/0068 ,  A61L31/10 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/606

摘要： An implantable medical device is provided that degrades upon contact with body fluids so as to limit its residence time within the body. The device is formed of a porous corrodible metal to simultaneously provide high strength and an accelerated corrosion rate. The corrosion rate of a device formed of metal subject to self-dissolution or of a combination of metals subject to galvanic corrosion is accelerated by its porous structure. Coating the corrodible metallic device with a degradable polymer serves to delay the onset of corrosion of the underlying metallic structure.

摘要翻译： 提供可植入医疗装置，其与体液接触时降解，以限制其在体内的停留时间。 该装置由多孔可腐蚀金属形成，以同时提供高强度和加速的腐蚀速率。 由自身溶解的金属或受电偶腐蚀的金属的组合形成的器件的腐蚀速度由其多孔结构加速。 用可降解聚合物涂覆可腐蚀的金属器件用于延迟下面的金属结构的腐蚀开始。

公开(公告)号：US20070185564A1

公开(公告)日：2007-08-09

申请号：US11736979

申请日：2007-04-18

申请人： Stephen Pacetti ,  Pamela Kramer

发明人： Stephen Pacetti ,  Pamela Kramer

IPC分类号： A61F2/06

CPC分类号： A61L31/18 ,  A61F2/91 ,  A61F2/92 ,  A61L31/022

摘要： The present invention includes a radiopaque stent comprising a cylindrical main body. The tubular main body comprises a cobalt chromium alloy that comprises cobalt, chromium and one or more radiopaque materials.

摘要翻译： 本发明包括一种包括圆柱形主体的不透射线支架。 管状主体包括钴铬合金，其包括钴，铬和一种或多种不透射线材料。

公开(公告)号：US20070184228A1

公开(公告)日：2007-08-09

申请号：US11784267

申请日：2007-04-05

申请人： Pamela Kramer

发明人： Pamela Kramer

IPC分类号： B32B1/08

CPC分类号： A61L27/306 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/106 ,  A61L29/16 ,  A61L31/082 ,  A61L31/088 ,  A61L31/10 ,  A61L31/14 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/606 ,  A61L2420/02 ,  B05B7/0006 ,  B05B7/203 ,  B05B7/205 ,  B05B7/224 ,  B05B7/226 ,  C23C4/12 ,  C23C24/04 ,  C23C28/00 ,  C23C28/028 ,  C23C28/321 ,  C23C28/322 ,  C23C28/34 ,  C23C28/3455 ,  C23C28/36 ,  Y10T428/12021 ,  Y10T428/12292 ,  Y10T428/12299 ,  Y10T428/13 ,  Y10T428/1376 ,  Y10T428/139

摘要： The invention relates to devices for the treatment of heart disease and particularly to endo-arterial prostheses, which are commonly called stents. More particularly, the invention relates to methods of manufacturing and coating stents utilizing thermal spray processing (TSP). In one aspect the invention involves the use of TSP for the manufacture of fine grained tubing for subsequent use as a stent or other tubular or ring-based implant, or the manufacture of intermediate sized tubing that may then be drawn to final size tubing and for the coating of a stent. An average grain size of less than 64 microns is achieved by the invention resulting in a stent having an annular wall average thickness of about eight or more grains.

公开(公告)号：US20070166496A1

公开(公告)日：2007-07-19

申请号：US11724766

申请日：2007-03-16

申请人： Pamela Kramer

发明人： Pamela Kramer

IPC分类号： B32B1/08

CPC分类号： A61L27/306 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/106 ,  A61L29/16 ,  A61L31/082 ,  A61L31/088 ,  A61L31/10 ,  A61L31/14 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2300/606 ,  A61L2420/02 ,  B05B7/0006 ,  B05B7/203 ,  B05B7/205 ,  B05B7/224 ,  B05B7/226 ,  C23C4/12 ,  C23C24/04 ,  C23C28/00 ,  C23C28/028 ,  C23C28/321 ,  C23C28/322 ,  C23C28/34 ,  C23C28/3455 ,  C23C28/36 ,  Y10T428/12021 ,  Y10T428/12292 ,  Y10T428/12299 ,  Y10T428/13 ,  Y10T428/1376 ,  Y10T428/139

摘要： The invention relates to devices for the treatment of heart disease and particularly to endo-arterial prostheses, which are commonly called stents. More particularly, the invention relates to methods of manufacturing and coating stents utilizing thermal spray processing (TSP). In one aspect the invention involves the use of TSP for the manufacture of fine grained tubing for subsequent use as a stent or other tubular or ring-based implant, or the manufacture of intermediate sized tubing that may then be drawn to final size tubing and for the coating of a stent. An average grain size of less than 64 microns is achieved by the invention resulting in a stent having an annular wall average thickness of about eight or more grains.

摘要翻译： 本发明涉及用于治疗心脏病，特别是通常称为支架的动脉内假体的装置。 更具体地说，本发明涉及使用热喷雾处理（TSP）制造和涂覆支架的方法。 在一个方面，本发明涉及使用TSP来制造细粒度管，用于随后用作支架或其它管状或环状植入物，或者制造中等尺寸的管，然后可以将其拉制成最终尺寸的管，并且用于 支架的涂层。 通过本发明实现小于64微米的平均粒度，得到具有大约八个或更多个颗粒的环形壁平均厚度的支架。