公开(公告)号：US10255647B2

公开(公告)日：2019-04-09

申请号：US12892793

申请日：2010-09-28

Applicant: Terrell Lee Rodman ,  Ningda Andy Dai ,  Patrick T. Bird ,  Paul L. Edwards ,  Ronald F. Richard ,  Peter Armstrong

Inventor： Terrell Lee Rodman ,  Ningda Andy Dai ,  Patrick T. Bird ,  Paul L. Edwards ,  Ronald F. Richard ,  Peter Armstrong

IPC: A61M16/10 ,  G06Q50/22 ,  G06Q10/06 ,  G06F19/00 ,  G16H40/63

Abstract: Disclosed are methods, systems, apparatus, and products, including a method for operating a respiratory care device that includes collecting at a respiratory care device data representative of operation of the respiratory care device, and communicating to a computing-based device external to the respiratory care device at least some of the collected data to control the operability of the respiratory care device. In some embodiments, the method may further include communicating to the respiratory care device data to controllably change one or more operation parameters of the respiratory care device to cause a change in the operation of the respiratory care device, changing the operation parameters of the respiratory care device according to the communicated data, and communicating to the external computing-based device resultant data representative of operation of the respiratory care device resulting from the controllable change to the one or more operation parameters.

公开(公告)号：US10198767B2

公开(公告)日：2019-02-05

申请号：US11880852

申请日：2007-07-24

Applicant: Peter Armstrong ,  Amy Farnstrom ,  Jon Werts

Inventor： Peter Armstrong ,  Amy Farnstrom ,  Jon Werts

IPC: G06Q40/06 ,  G06Q40/04 ,  G06Q30/06 ,  G06Q40/00

Abstract: An enhanced system and method for executing options trades are disclosed. The lead market maker entitlements are integrated with sophisticated order types, including dark order types, so that the lead marker maker is guaranteed an allocation of the trade if the lead market maker is at the NBBO when an order priced at or better than the NBBO is received. The lead market maker is not provided an opportunity to price improve to execute with a specific incoming order. Additionally, market makers who are not the lead market maker in an option series may be granted the privileges of a lead market maker for the purpose of executing with a specific incoming directed order if the designated market maker is at the NBBO when a directed order priced at or better than the NBBO is received. The system and method disclosed encourages market makers to quote the best price possible, which in turn has the effect of narrowing spreads. Furthermore, as only displayed orders at the NBBO are eligible to execute ahead of market makers quoting at the NBBO, the system and method encourages users to display their best prices and sizes to the marketplace.

公开(公告)号：US09974918B2

公开(公告)日：2018-05-22

申请号：US13082345

申请日：2011-04-07

Applicant: Peter Armstrong ,  Ronald Richard ,  Paul Edwards ,  Ningda Andy Dai

Inventor： Peter Armstrong ,  Ronald Richard ,  Paul Edwards ,  Ningda Andy Dai

IPC: A61M16/10 ,  B01D53/047 ,  C01B13/02 ,  A61M16/06 ,  A61M16/20 ,  A61M11/06

CPC classification number: A61M16/10 ,  A61M11/06 ,  A61M16/0677 ,  A61M16/101 ,  A61M16/107 ,  A61M16/204 ,  A61M2016/1025 ,  A61M2205/18 ,  A61M2205/3584 ,  A61M2205/3653 ,  A61M2205/42 ,  A61M2205/505 ,  A61M2205/8206 ,  A61M2205/8262 ,  A61M2205/8268 ,  A61M2209/084 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/63 ,  B01D53/047 ,  B01D2253/108 ,  B01D2253/25 ,  B01D2256/12 ,  B01D2257/102 ,  B01D2259/40005 ,  B01D2259/40009 ,  B01D2259/4061 ,  B01D2259/4145 ,  B01D2259/4533 ,  B01D2259/4541 ,  C01B13/0251 ,  C01B13/0259

Abstract: Devices, systems, and methods, include an oxygen delivery device that includes an oxygen delivery module, at least one sensor to detect patient breathing, and a controller configured to control the oxygen delivery module to cause the oxygen delivery module to deliver oxygen to the patient based on data from the at least one sensor such that in response to a determination, based on data from the at least one sensor, that no breathing is detected for a first pre-determined period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in continuous flow mode, and in response to a determination, based on additional data from the at least one sensor, that breathing is detected for a second period of time, the controller causes the oxygen delivery module to deliver oxygen to the patient in a pulse flow mode.

公开(公告)号：US09103109B2

公开(公告)日：2015-08-11

申请号：US14579671

申请日：2014-12-22

Applicant: Peter Armstrong ,  Wayne Armstrong

Inventor： Peter Armstrong ,  Wayne Armstrong

IPC: E04B1/24 ,  E04B5/29 ,  E04C3/06 ,  E04C3/32 ,  E04H1/04 ,  E04C3/294 ,  E04C3/04

CPC classification number: E04B1/2403 ,  E04B1/24 ,  E04B5/29 ,  E04B2001/2415 ,  E04B2001/2418 ,  E04B2001/2448 ,  E04B2001/2451 ,  E04B2001/2463 ,  E04B2001/2469 ,  E04B2001/2472 ,  E04B2001/2484 ,  E04B2103/06 ,  E04C3/06 ,  E04C3/294 ,  E04C3/32 ,  E04C2003/0452 ,  E04H1/04

Abstract: Modular support systems for supporting multi story buildings including plates having bottom major faces and top major faces, the plates defining bolt holes extending through the plates, vertical columns extending from bottom ends to top ends opposite the bottom ends, the bottom ends of the vertical columns being welded to the top major faces of the plates, and horizontal columns having bottom sides and top sides opposite the bottom sides, the bottom sides of the horizontal columns being welded to the top end of the vertical columns. In some examples, the horizontal column defines bolt holes being positioned to align with the bolt holes defined in the plate. Some examples include pluralities of structural units selectively fastened together in a vertical arrangement, with each structural unit configured to selectively couple with vertically adjacent structural unit. Some examples define buildings including disclosed support systems.

Abstract translation: 用于支持多层建筑的模块化支撑系统，包括具有底部主面和顶面主面板的板，限定螺栓孔延伸穿过板的板，垂直柱从底端延伸到与底端相对的顶端，垂直柱的底端 焊接到板的顶部主面上，水平柱具有底侧和与底侧相对的顶侧，水平柱的底侧焊接到垂直柱的顶端。 在一些示例中，水平柱限定螺栓孔定位成与限定在板中的螺栓孔对齐。 一些示例包括以垂直布置选择性地紧固在一起的多个结构单元，其中每个结构单元被配置为选择性地与垂直相邻的结构单元耦合。 一些示例定义了包括公开的支持系统的建筑物。

公开(公告)号：US20140141022A1

公开(公告)日：2014-05-22

申请号：US13815721

申请日：2013-03-15

Applicant: PETER ARMSTRONG THOMPSON ,  JEFFREY A. LEDBETTER ,  MARTHA SUSAN HAYDEN-LEDBETTER ,  LAURA SUE GROSMAIRE ,  ROBERT BADER ,  WILLIAM BRADY

Inventor： PETER ARMSTRONG THOMPSON ,  JEFFREY A. LEDBETTER ,  MARTHA SUSAN HAYDEN-LEDBETTER ,  LAURA SUE GROSMAIRE ,  ROBERT BADER ,  WILLIAM BRADY

IPC: C07K16/18

CPC classification number: C07K16/28 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/18 ,  C07K16/2803 ,  C07K16/2809 ,  C07K16/2818 ,  C07K16/2827 ,  C07K16/2833 ,  C07K16/2851 ,  C07K16/2875 ,  C07K16/2878 ,  C07K16/2887 ,  C07K16/2896 ,  C07K16/30 ,  C07K16/46 ,  C07K16/468 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/52 ,  C07K2317/53 ,  C07K2317/622 ,  C07K2317/64 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2319/30

Abstract: Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.

Abstract translation: 提供具有免疫球蛋白效应子功能的多价结合肽，包括双特异性结合肽，以及编码核酸，载体和宿主细胞以及制备这些肽的方法和使用这些肽治疗或预防各种疾病的方法 ，疾病或病症，以及改善与这种疾病，病症或病症相关的至少一种症状。

公开(公告)号：US20120034245A9

公开(公告)日：2012-02-09

申请号：US12304562

申请日：2007-06-12

Applicant: Peter Armstrong Thompson ,  Jeffrey A. Ledbetter ,  Martha Susan Hayden-Ledbetter ,  Laura Sue Grosmaire ,  Robert Bader ,  William Brady

Inventor： Peter Armstrong Thompson ,  Jeffrey A. Ledbetter ,  Martha Susan Hayden-Ledbetter ,  Laura Sue Grosmaire ,  Robert Bader ,  William Brady

IPC: A61K39/395 ,  C07K16/46 ,  C07H21/00 ,  C12N15/63 ,  C12N5/10 ,  A61P37/06 ,  A61P29/00 ,  A61P3/10 ,  A61P19/02 ,  A61P11/06 ,  A61P25/00 ,  A61P17/06 ,  C07K19/00 ,  A61P35/00

CPC classification number: C07K16/28 ,  A61K2039/505 ,  A61K2039/507 ,  C07K16/18 ,  C07K16/2803 ,  C07K16/2809 ,  C07K16/2818 ,  C07K16/2827 ,  C07K16/2833 ,  C07K16/2851 ,  C07K16/2875 ,  C07K16/2878 ,  C07K16/2887 ,  C07K16/2896 ,  C07K16/30 ,  C07K16/46 ,  C07K16/468 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/52 ,  C07K2317/53 ,  C07K2317/622 ,  C07K2317/64 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2319/30

Abstract: Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.

Abstract translation: 提供具有免疫球蛋白效应子功能的多价结合肽，包括双特异性结合肽，以及编码核酸，载体和宿主细胞以及制备这些肽的方法和使用这些肽治疗或预防各种疾病的方法 ，疾病或病症，以及改善与这种疾病，病症或病症相关的至少一种症状。

公开(公告)号：US20110217302A1

公开(公告)日：2011-09-08

申请号：US13123509

申请日：2009-10-09

Applicant: Valerie Odegard ,  Catherine J. McMahan ,  Peter Robert Baum ,  Peter Armstrong Thompson ,  Philip Tan ,  John W. Blankenship ,  Sateesh Kumar Natarajan

Inventor： Valerie Odegard ,  Catherine J. McMahan ,  Peter Robert Baum ,  Peter Armstrong Thompson ,  Philip Tan ,  John W. Blankenship ,  Sateesh Kumar Natarajan

IPC: A61K39/395 ,  C12N15/63 ,  G01N33/566 ,  C07K19/00 ,  C07H21/00 ,  C07K16/46 ,  A61P37/06 ,  A61P11/06 ,  A61P3/10 ,  A61P19/02

CPC classification number: C07K16/2809 ,  A61K39/3955 ,  A61K2039/505 ,  C07K16/46 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/524 ,  C07K2317/622 ,  C07K2317/76 ,  C07K2319/00

Abstract: Single chain fusion proteins that specifically bind to a TCR complex or a component thereof, such as TCRα, TCRβ, or CD3ε, along with compositions and methods of use thereof are provided.

Abstract translation: 提供了特异性结合TCR复合物或其组分的单链融合蛋白，例如TCRα，TCR＆bgr，或CD3和egr，以及组合物及其使用方法。

公开(公告)号：US20110192257A1

公开(公告)日：2011-08-11

申请号：US13023390

申请日：2011-02-08

Applicant: Peter Armstrong

Inventor： Peter Armstrong

IPC: B25B29/02

CPC classification number: B25B29/02

Abstract: A hydraulic bolt tensioner has a reduced height by virtue of inner seals between a cylinder and piston being aligned along a same plane. The tensioner also has a reduced width by virtue of carbon fiber would about the tensioner's housing, reducing the need for a certain thickness of material used for the tensioner's housing.

Abstract translation: 液压螺栓张紧器由于气缸和活塞之间的内部密封沿同一平面对准而具有减小的高度。 张紧器还通过碳纤维围绕张紧器的外壳而具有减小的宽度，减少了用于张紧器壳体的一定厚度的材料的需要。

公开(公告)号：US20110158995A1

公开(公告)日：2011-06-30

申请号：US13056141

申请日：2009-07-28

Applicant: Philip Tan ,  Laura Sue Grosmaire ,  Peter Robert Baum ,  Peter Armstrong Thompson

Inventor： Philip Tan ,  Laura Sue Grosmaire ,  Peter Robert Baum ,  Peter Armstrong Thompson

IPC: A61K39/395 ,  C12P21/04 ,  C12N5/10 ,  C12N15/63 ,  C07K16/00 ,  C07H21/04 ,  A61P19/02 ,  A61P29/00 ,  A61P37/00

CPC classification number: C07K14/7056 ,  A61K2039/505 ,  C07K16/2803 ,  C07K16/2851 ,  C07K16/2896 ,  C07K2317/31 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2319/30 ,  C07K2319/32 ,  C07K2319/74

Abstract: This disclosure provides a multi-specific fusion protein composed of a CD72-ligand binding domain and another binding domain specific for a heterologous target, such as a B-cell specific protein. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.

Abstract translation: 本公开提供由CD72-配体结合结构域和异源靶特异性的另一结合结构域（例如B细胞特异性蛋白质）组成的多特异性融合蛋白。 多特异性融合蛋白还可以包括分隔其他结构域的中间结构域。 本公开还提供了编码多特异融合蛋白的多核苷酸，融合蛋白的组合物，以及使用多特异性融合蛋白和组合物的方法。

公开(公告)号：US20130195850A1

公开(公告)日：2013-08-01

申请号：US13678128

申请日：2012-11-15

Applicant: Philip TAN ,  Sandy Alexander SIMON ,  Charles G. CERVENY ,  Christy Anne NILSSON ,  William BRADY ,  Jeffrey A. LEDBETTER ,  Martha Susan HAYDEN-LEDBETTER ,  Peter Armstrong THOMPSON ,  Cecile MORALES

Inventor： Philip TAN ,  Sandy Alexander SIMON ,  Charles G. CERVENY ,  Christy Anne NILSSON ,  William BRADY ,  Jeffrey A. LEDBETTER ,  Martha Susan HAYDEN-LEDBETTER ,  Peter Armstrong THOMPSON ,  Cecile MORALES

IPC: C07K16/46

CPC classification number: A61K39/39541 ,  A61K31/4184 ,  A61K38/16 ,  A61K39/39558 ,  A61K2039/505 ,  C07K16/2896 ,  C07K16/3061 ,  C07K16/461 ,  C07K2317/24 ,  C07K2317/50

Abstract: The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.

Abstract translation: 本公开内容提供人源化抗CD37小模块化免疫药物（SMIP）分子，以及CD37-特异性结合分子（例如抗CD37SMIP蛋白或抗体）与双功能化学治疗剂（例如苯达莫司汀）的协同组合疗法，其可以 同时或顺序施用，用于治疗或预防B细胞相关的自身免疫性，炎症性或过度增殖性疾病。