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    NATURAL MICROORGANISMS WHICH ARE NATURALLY CAPABLE OF BINDING TOXINS AND/OR TOXIN RECEPTORS
    1.
    发明申请
    NATURAL MICROORGANISMS WHICH ARE NATURALLY CAPABLE OF BINDING TOXINS AND/OR TOXIN RECEPTORS 审中-公开

    公开(公告)号：US20190257832A1

    公开(公告)日：2019-08-22

    申请号：US16318532

    申请日：2017-07-18

    申请人： Philippe ULSEMER ,  Steffen GOLETZ ,  Peter GOETZ

    发明人： Philippe ULSEMER ,  Steffen GOLETZ ,  Peter GOETZ

    IPC分类号： G01N33/569 ,  C12N1/16 ,  C12N1/20 ,  A61P1/00 ,  A61K35/74

    摘要： The present invention relates to means and method for isolating naturally-occurring microorganisms (non-pathogenic bacteria, yeasts or fungi) capable of binding toxins from microorganisms such as bacteria, viruses, fungi, yeasts, or protozoans and/or receptors for these toxins on the surface of mammalian cells, thereby making these receptors inaccessible for said toxins. The naturally-occurring microorganisms that are obtainable by the means and methods of the present invention can be used for adsorbing toxins from pathogenic microorganisms and/or blocking receptors for such toxins on the surface of mammalian cells. These toxin-receptor interactions are known to be critical for disease pathogenesis, making both the toxins and receptors a target for the naturally-occurring microorganisms of the present invention.

    MICROORGANISMS CARRYING A TUMOR ANTIGEN
    6.
    发明申请
    MICROORGANISMS CARRYING A TUMOR ANTIGEN 有权
    携带肿瘤抗原的微生物

    公开(公告)号：US20140302093A1

    公开(公告)日：2014-10-09

    申请号：US14239711

    申请日：2012-08-22

    申请人： Steffen Goletz ,  Philippe Ulsemer ,  Kawe Toutounian

    发明人： Steffen Goletz ,  Philippe Ulsemer ,  Kawe Toutounian

    IPC分类号： A61K39/02

    CPC分类号： A61K39/0216 ,  A61K39/0011 ,  A61K2039/5154 ,  A61K2039/585 ,  C07K16/1257 ,  C12N1/20 ,  C12R1/01

    摘要： The present invention pertains to microorganisms of the species Bacteroides xylanisolvens expressing a core-1 antigen on their surface. These microorganisms are in particular useful for the prophylaxis and treatment of core-1 positive diseases and are particularly characterized by a stable, homogenous high core-1 expression. Also provided are pharmaceutical compositions which comprise respective core-1 positive microorganisms or fractions thereof.

    摘要翻译： 本发明涉及在其表面表达核心-1抗原的拟杆菌木聚糖异构酶的微生物。 这些微生物特别可用于预防和治疗核心-1阳性疾病，特别是特征在于稳定的，均匀的高核心-1表达。 还提供了包含各自的核心-1阳性微生物或其级分的药物组合物。

    Fermentation process
    7.
    发明授权
    Fermentation process 有权
    发酵过程

    公开(公告)号：US08741365B2

    公开(公告)日：2014-06-03

    申请号：US12991827

    申请日：2009-05-13

    申请人： Steffen Goletz ,  Philippe Ulsemer

    发明人： Steffen Goletz ,  Philippe Ulsemer

    IPC分类号： A23C9/12 ,  A23C9/127 ,  C12N1/20 ,  C12P39/00 ,  C12P7/56 ,  A23B4/12

    CPC分类号： A23C9/1203 ,  A61K39/0011 ,  A61K2039/523 ,  A61K2039/542

    摘要： The present disclosure relates in one embodiment to a method of producing a fermented food, wherein a raw food material is combined with a starter culture for fermentation, wherein at least one microorganism of the genus Bacteroides and/or at least one microorganism having at least a cell surface structure which corresponds to a human carbohydrate structure is added. Further disclosed are processing aids and fermented foods containing respective microorganisms.

    摘要翻译： 在一个实施方案中，本公开涉及一种生产发酵食品的方法，其中将生食材料与用于发酵的起始培养物组合，其中至少一种拟杆菌属和/或至少一种微生物的微生物具有至少一种 加入对应于人碳水化合物结构的细胞表面结构。 进一步公开的是加工助剂和含有微生物的发酵食品。