Signal Multiplexing and Signal Amplification
    2.
    发明申请
    Signal Multiplexing and Signal Amplification 审中-公开
    信号复用和信号放大

    公开(公告)号:US20120003648A1

    公开(公告)日:2012-01-05

    申请号:US13175393

    申请日:2011-07-01

    IPC分类号: C12Q1/68

    摘要: Disclosed are methods, compositions and kits for amplifying signals for detecting the presence, quantity and/or sequence of nucleic acids and proteins, as well as methods, compositions and kits for increasing the number of such targets simultaneously detectable in a sample. Detection may be, for instance, in vivo, in cellulo or in situ. Amplification of signal is achieved by way of hybridization of nucleic acid label probe systems and structures. Increase in target multiplex capacity is achieved by way of varying the type of labels utilized in the nucleic acid label probe system.

    摘要翻译: 公开了用于扩增用于检测核酸和蛋白质的存在,数量和/或序列的信号的方法,组合物和试剂盒,以及用于增加样品中同时可检测的这些靶标数量的方法,组合物和试剂盒。 检测可以是例如体内,纤维素或原位。 通过核酸标记探针系统和结构的杂交实现信号的扩增。 通过改变在核酸标记探针系统中使用的标记类型来实现目标多重容量的增加。