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公开(公告)号：US20060000712A1
公开(公告)日：2006-01-05
申请号：US11120098
申请日：2005-05-02
申请人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
发明人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Hochstrasser
CPC分类号： G01N27/44773
摘要： A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.
摘要翻译： 用于生物分子样品材料，特别是蛋白质混合物的分离装置和分离方法。 为此，在分离平面的区域30中提供用于样品材料的组分的二维和优选的电泳分离的分离元件10。 根据本发明，提出了分离元件10具有通道或转移结构14，用于将分离的样品组分在与分离平面成直角的运输方向上局部分解排放到支撑表面16上，其优选地适合 用于质谱分析。
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公开(公告)号：US07645369B2
公开(公告)日：2010-01-12
申请号：US11120098
申请日：2005-05-02
申请人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Anton Hochstrasser
发明人： Hans-Joachim Hoeltke , Albert Roeder , Alois Rainer , Peter Berndt , Carlo Effenhauser , Hanno Langen , Remo Anton Hochstrasser
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44773
摘要： A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation element 10 for the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in area 30 of a separation plane. According to the invention it is proposed that the separation element 10 has a channel or transfer structure 14 for the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surface 16 that is preferably suitable for mass spectroscopic analyses.
摘要翻译： 用于生物分子样品材料，特别是蛋白质混合物的分离装置和分离方法。 为此，在分离平面的区域30中提供用于样品材料的组分的二维和优选的电泳分离的分离元件10。 根据本发明，提出了分离元件10具有通道或转移结构14，用于将分离的样品组分在与分离平面成直角的运输方向上局部分解排放到支撑表面16上，其优选地适合 用于质谱分析。
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公开(公告)号：US4679165A
公开(公告)日：1987-07-07
申请号：US628585
申请日：1984-07-06
申请人： Alois Rainer
发明人： Alois Rainer
CPC分类号： G06F7/5338
摘要： A multiplication unit for n-place binary numbers has a first register containing the multiplicand, and accumulator, and an arithmetic unit having operand inputs connected to the first register and to the accumulator. The operation to be undertaken by the arithmetic unit is to find by the bits of a multiplier which is contained in a second register, the second register being connected to an operation instruction input of the arithmetic unit. A multiplexer having inputs connected to the outputs of the second register through-connects the bits of five adjacent multiplier places to the inputs of a logic circuit, which derives the operation instruction for the arithmetic unit. The logic circuit also supplies an instruction to a mulitple shift unit interconnected between the output of the arithmetic unit and the input of the accumulator.
摘要翻译： 用于n位二进制数的乘法单元具有包含被乘数和累加器的第一寄存器，以及具有连接到第一寄存器和累加器的操作数输入的算术单元。 由算术单元进行的操作是通过包含在第二寄存器中的乘法器的位来查找第二寄存器，其连接到运算单元的操作指令输入。 具有连接到第二寄存器的输出的输入的多路复用器通过将五个相邻乘法器位的位连接到逻辑电路的输入，该逻辑电路的输入导出运算单元的操作指令。 逻辑电路还向在运算单元的输出和累加器的输入之间互连的多个移位单元提供指令。
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公开(公告)号：USD677400S1
公开(公告)日：2013-03-05
申请号：US29368504
申请日：2010-08-25
申请人： Thomas Blaettler , Alois Rainer , Armin Bucher
设计人： Thomas Blaettler , Alois Rainer , Armin Bucher
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公开(公告)号：US08951780B2
公开(公告)日：2015-02-10
申请号：US12261476
申请日：2008-10-30
CPC分类号： B01L3/508 , B01D29/05 , B01L3/502 , B01L3/5021 , B01L2200/0631 , B01L2300/0681 , B01L2300/069
摘要： The invention concerns a method for isolating and purifying nucleic acids from large sample volumes and a device suitable for this. The device comprises a funnel, a separating column, and a tab which are detachable from each other. The method according to the invention in which the device according to the invention is used ensures a higher yield of nucleic acids.
摘要翻译： 本发明涉及从大样品体积分离和纯化核酸的方法以及适用于此的装置。 该装置包括可以彼此分离的漏斗，分离柱和突片。 根据本发明的方法，其中使用根据本发明的装置确保较高的核酸产量。
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公开(公告)号：US08157746B2
公开(公告)日：2012-04-17
申请号：US11272187
申请日：2005-11-10
申请人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
发明人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
CPC分类号： A61B17/32053 , A61B10/0233
摘要： The present invention relates to a device for separating a tissue part from brain material, the device comprising a circular blade which continues as the wall of a cylindrical or substantially cylindrical hollow body, at the end of which a grid is arranged perpendicular to the cylinder axis. The invention further relates to the use of the device in a method for separating a tissue part from brain material and to a kit containing one or more devices according to the invention.
摘要翻译： 本发明涉及一种用于从脑材料中分离组织部分的装置，该装置包括圆形叶片，该圆形叶片作为圆柱形或基本上圆柱形的中空本体的壁继续，在其末端处格栅垂直于圆柱体轴线布置 。 本发明还涉及在根据本发明的用于将组织部分与脑材料分离的方法和包含一种或多种装置的试剂盒中的用途的用途。
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公开(公告)号：US20070148035A1
公开(公告)日：2007-06-28
申请号：US11564441
申请日：2006-11-29
申请人： Armin Tgetgel , Joachim Siedel , Alois Rainer , Wolf-Dieter Engel
发明人： Armin Tgetgel , Joachim Siedel , Alois Rainer , Wolf-Dieter Engel
CPC分类号： A61L2/206
摘要： A method and a disposable to avoid false nucleic acid amplification results based on the alklylation of DNA present at surfaces of disposables. More particularly, the present invention is directed to an improved method and a disposable, whereby the alkylation of DNA is performed using ethylene oxide.
摘要翻译： 基于存在于一次性物品表面的DNA的烷基化反应的方法和一次性以避免假核酸扩增结果。 更具体地说，本发明涉及一种改进的方法和一次性物质，由此使用环氧乙烷进行DNA的烷基化。
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公开(公告)号：US20100124779A1
公开(公告)日：2010-05-20
申请号：US12616822
申请日：2009-11-12
申请人： Alois Rainer , Andre Stutz
发明人： Alois Rainer , Andre Stutz
CPC分类号： B01L3/5082 , B01L3/508 , B01L7/52 , B01L2200/12 , B01L2300/12 , B29C45/16
摘要： Reaction containers, such as plastic capillaries having an optimized volume-to-surface ratio that are suitable for real-time nucleic acid amplification (rtPCR) applications are disclosed as well as a method for the production of the reaction containers, in particularly the trtPCR plastic capillaries via a 2-step molding process. In the process, a capillary section is closed at one end, a tubular section is provided opened at both ends, and a linkage is provided between the capillary section and the tubular section, wherein the linkage is a fused joint designed to permanently link the open end of the capillary section to one of the open ends of the tubular section thus forming a reaction container having one opening, and in which the fused joint produces light scatter upon illumination.
摘要翻译： 公开了具有适于实时核酸扩增（rtPCR）应用的具有优化的体积对表面比的塑料毛细管的反应容器以及用于生产反应容器的方法，特别是trtPCR塑料 毛细管通过两步成型过程。 在该过程中，毛细管部分在一端封闭，管状部分设置在两端开口，并且在毛细管部分和管状部分之间设置有连杆，其中连杆是设计成永久连接开口 从而形成具有一个开口的反应容器，并且熔融接头在照射时产生光散射。
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公开(公告)号：US20060122641A1
公开(公告)日：2006-06-08
申请号：US11272187
申请日：2005-11-10
申请人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
发明人： Walter Eberle , Peter Hloch , Christoph Hundt , Alois Rainer
CPC分类号： A61B17/32053 , A61B10/0233
摘要： The present invention relates to a device for separating a tissue part from brain material, said device comprising a circular blade which continues as the wall of a cylindrical or substantially cylindrical hollow body, at the end of which a grid is arranged perpendicular to the cylinder axis. The invention further relates to the use of the device in a method for separating a tissue part from brain material and to a kit containing one or more devices according to the invention.
摘要翻译： 本发明涉及一种用于从脑材料中分离组织部分的装置，所述装置包括圆形叶片，该圆形叶片作为圆柱形或基本上圆柱形的中空体的壁延伸，其端部垂直于圆柱体轴线布置网格 。 本发明还涉及在根据本发明的用于将组织部分与脑材料分离的方法和包含一种或多种装置的试剂盒中的用途的用途。
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10.发明授权Circuit for CSD-coding of a binary number represented in two's complement 失效用于二进制数的CSD编码的电路用二进制补码表示
公开(公告)号：US4623872A
公开(公告)日：1986-11-18
申请号：US625035
申请日：1984-06-27
申请人： Alois Rainer
发明人： Alois Rainer
CPC分类号： H03M7/04
摘要： A circuit for coding a binary number represented in two's complement in a CSD-code wherein it is impossible for two immediately adjacent binary digits to respectively exhibit a "1". The circuit is simply constructed and has a high operating speed. This is achieved by means of a series of logic components which respectively evaluate according to an exclusive-OR function and which create an output bit -1 from two respectively adjacent binary digits of the number to be encoded upon appearance of the bit combination 1,0. A series of second logic components create a CSD-coded bit combination 0, 1 from two respectively adjacent first logic components having the output bits 1,-1, but which accept the output bits of the remaining first logic components into the CSD-coded bit combination in unaltered fashion. The circuit is used in signal processors.
摘要翻译： 用于以CSD代码对二进制补码表示的二进制数进行编码的电路，其中两个紧邻的二进制数字不可能分别呈现“1”。 电路简单构造，运行速度快。 这是通过一系列逻辑组件实现的，这些逻辑组件根据异或功能分别评估，并且在出现位组合1,0时将从要编码的数字的两个分别相邻的二进制数字中产生输出位-1 。 一系列第二逻辑部件从具有输出位1，-1的两个分别相邻的第一逻辑部件创建CSD编码位组合0,1，但是将其余第一逻辑部件的输出位接受到CSD编码位 以不变的方式组合。 电路用于信号处理器。
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