公开(公告)号：US5895578A

公开(公告)日：1999-04-20

申请号：US874324

申请日：1997-06-13

申请人： Laurent Simard ,  Renato Pedrazzi

发明人： Laurent Simard ,  Renato Pedrazzi

IPC分类号： A61L2/18 ,  A61M1/14 ,  A61M1/16 ,  B01D65/02 ,  A61L2/16

CPC分类号： A61M1/169

摘要： A method for disinfection of the hydraulic circuit of a dialysis machine, comprising an inlet (E) for connection to an external water source and a plurality of open lines (1, 2, 4a, 4b, 26) intended to be connected, in an operational configuration of the machine, to different consumable accessories, comprises the steps of:closing the open lines on the hydraulic circuit in such a way as to form a closed network of lines;bringing a reservoir (40) containing a concentrated disinfection liquid into communication with the hydraulic circuit, in proximity to the inlet;instigating a proportional flow of water and of concentrated disinfection liquid in the hydraulic circuit in such a way as to produce a first liquid having a bactericidal action;interrupting the flow of water and of concentrated disinfection liquid when the hydraulic circuit is filled with bactericidal liquid, the initial volume of concentrated disinfection liquid in the reservoir being chosen such that at the end of the filling of the hydraulic circuit, a residual volume remains in the reservoir (40);adding a volume of water to the residual volume in the reservoir (40) in order to produce a second liquid;emptying the hydraulic circuit of the bactericidal liquid;instigating simultaneously a proportional flow of water and of the second liquid in the hydraulic circuit in such a way as to produce a third liquid having a bacteriostatic action and capable of remaining in the hydraulic circuit for at least twelve hours without causing corrosion there;filling the hydraulic circuit with bacteriostatic liquid.

摘要翻译： 一种用于消毒透析机的液压回路的方法，包括用于连接到外部水源的入口（E）和用于连接的多个开放管线（1,2a，4b，26） 该机器的操作配置，不同的消耗品附件包括以下步骤：关闭液压回路上的开放线路以形成闭合的线路网络; 将含有浓缩消毒液体的储存器（40）与所述液压回路连通，在所述入口附近; 在液压回路中引发水和浓缩消毒液体的比例流，以产生具有杀菌作用的第一液体; 当液压回路充满杀菌液体时，中断水流和浓缩消毒液体，选择储存器中浓缩消毒液的初始体积，使得在液压回路填充结束时，剩余体积保持在 储存器（40）; 向容器（40）中的剩余体积加入一定量的水以产生第二液体; 排空杀菌液体的液压回路; 同时在液压回路中同时施加水和第二液体的比例流，以产生具有抑菌作用的第三液体，并能够在液压回路中保持至少十二个小时，而不会在那里引起腐蚀; 用抑菌液填充液压回路。

公开(公告)号：US06730233B2

公开(公告)日：2004-05-04

申请号：US09980864

申请日：2002-04-12

申请人： Renato Pedrazzi

发明人： Renato Pedrazzi

IPC分类号： A61M114

CPC分类号： A61M1/342 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3669 ,  A61M39/28 ,  A61M2230/30

摘要： A dialysis machine includes an extracorporeal blood circuit having an arterial pipe and a venous pipe respectively connected to an inlet and an outlet of a blood compartment of a filter. The blood compartment and a dialysis liquid compartment of the filter are separated by a semi-permeable membrane. The machine is configured to determine a sequence of infusion of a liquid in the extracorporeal blood circuit, from at least one characteristic value correlated with the concentration of the blood and/or a filtration efficiency of the filter, and to infuse the infusion solution in the arterial pipe and in the venous pipe in accordance with the determined infusion sequence.

摘要翻译： 透析机包括具有分别连接到过滤器的血液室的入口和出口的动脉管和静脉管的体外血液回路。 过滤器的血液隔室和透析液室由半透膜隔开。 该机器被配置为从与血液浓度和/或过滤器的过滤效率相关的至少一个特征值确定体外血液回路中液体的输注顺序，并且将输注溶液注入到 根据确定的输液顺序在动脉管和静脉管中。

公开(公告)号：US4702675A

公开(公告)日：1987-10-27

申请号：US761933

申请日：1985-08-02

申请人： Mauro Aldrovandi ,  Domenico Cianciavicchia ,  Renato Pedrazzi

发明人： Mauro Aldrovandi ,  Domenico Cianciavicchia ,  Renato Pedrazzi

IPC分类号： A61M1/10 ,  A61M1/36 ,  G01L9/00 ,  F04B43/12

CPC分类号： G01L9/0004 ,  A61M1/3639 ,  A61M2205/3344 ,  A61M2205/3351

摘要： Apparatus for circulating a liquid along a tubular conduit comprises a peristaltic pump provided with a rotor which acts through the intermediary of rollers, on an elastically deformable tube disposed in series along the mentioned tubular conduit and a device mounted outside on a section of the deformable tube for emitting an electric signal depending on the deformation induced in operation in the section of tube by the pressure of the said pumped liquid.

摘要翻译： 用于沿管状管道循环液体的装置包括设置有转子的蠕动泵，所述转子通过辊的中间作用，沿着所述管状导管串联布置的可弹性变形的管和安装在可变形管的一部分上的装置 用于根据所述泵送液体的压力在管的截面中在操作中引起的变形发射电信号。

公开(公告)号：US08881600B2

公开(公告)日：2014-11-11

申请号：US11993204

申请日：2005-07-01

申请人： Anna Puppini ,  Renato Pedrazzi ,  Mauro Suffritti

发明人： Anna Puppini ,  Renato Pedrazzi ,  Mauro Suffritti

IPC分类号： G01F1/00 ,  A61M1/34

CPC分类号： G01N15/0826 ,  A61M1/165 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/3413 ,  A61M2205/3331 ,  A61M2205/705 ,  G01L13/00 ,  G01N2015/084

摘要： In a process for testing filters (4) and (13) of treatment fluid of a hemodiafiltration apparatus (1), each filter has a wet semipermeable membrane (5, 14) which separates a gas-filled first chamber (6 and 15) from a liquid-filled second chamber (7 and 16). The first chambers are pressurised by a pump (19) supplying air, while the second chambers are placed in depression by a drainage pump (17) of used dialysis fluid. A first closed system is formed which includes the first chambers and a second closed system is formed which includes the second chambers. Two pressure gauges (P1 and P2) monitor the pressure in the two closed systems for a predetermined time. The monitoring provides indications relating to the filter integrity.

摘要翻译： 在用于测试血液透析过滤装置（1）的处理流体的过滤器（4）和（13）的过程中，每个过滤器具有湿气半透膜（5,14），其将充气的第一室（6和15）与 充满液体的第二室（7和16）。 第一腔室由供应空气的泵（19）加压，而第二腔室由所用透析液体的排水泵（17）放置在凹陷中。 形成包括第一室的第一闭合系统，并且形成包括第二室的第二封闭系统。 两个压力表（P1和P2）监测两个封闭系统中的压力达预定时间。 监控提供了与过滤器完整性相关的指示。

公开(公告)号：US20090151470A1

公开(公告)日：2009-06-18

申请号：US11993204

申请日：2005-07-01

申请人： Anna Puppini ,  Renato Pedrazzi ,  Mauro Suffritti

发明人： Anna Puppini ,  Renato Pedrazzi ,  Mauro Suffritti

IPC分类号： G01F1/00 ,  G01N1/14

CPC分类号： G01N15/0826 ,  A61M1/165 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/3413 ,  A61M2205/3331 ,  A61M2205/705 ,  G01L13/00 ,  G01N2015/084

摘要： In a process for testing filters (4) and (13) of treatment fluid of a hemodiafiltration apparatus (1), each filter has a wet semipermeable membrane (5, 14) which separates a gas-filled first chamber (6 and 15) from a liquid-filled second chamber (7 and 16). The first chambers are pressurised by a pump (19) supplying air, while the second chambers are placed in depression by a drainage pump (17) of used dialysis fluid. A first closed system is formed which includes the first chambers and a second closed system is formed which includes the second chambers. Two pressure gauges (P1 and P2) monitor the pressure in the two closed systems for a predetermined time. The monitoring provides indications relating to the filter integrity.

摘要翻译： 在用于测试血液透析过滤装置（1）的处理流体的过滤器（4）和（13）的过程中，每个过滤器具有湿气半透膜（5,14），其将充气的第一室（6和15）与 充满液体的第二室（7和16）。 第一腔室由供应空气的泵（19）加压，而第二腔室由所用透析液体的排水泵（17）放置在凹陷中。 形成包括第一室的第一闭合系统，并且形成包括第二室的第二封闭系统。 两个压力表（P1和P2）监测两个封闭系统中的压力达预定时间。 监控提供了与过滤器完整性相关的指示。

公开(公告)号：US07147616B2

公开(公告)日：2006-12-12

申请号：US09979307

申请日：2001-01-12

申请人： Renato Pedrazzi ,  Paolo Rovatti

发明人： Renato Pedrazzi ,  Paolo Rovatti

IPC分类号： A61M37/00 ,  C02F1/44 ,  A61L2/16 ,  A61L101/00

CPC分类号： A61M1/3643 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/3644 ,  A61M1/3646 ,  A61M1/365 ,  A61M1/3652 ,  A61M2205/3331 ,  A61M2205/3351 ,  A61M2205/3355

摘要： A method for emptying a blood circuit of an apparatus for the extracorporeal treatment of blood after interrupting a treatment session. The apparatus has a blood treatment device with first and second compartments separated by a semi permeable membrane, an arterial pipe connected to an inlet of the first compartment, a venous pipe connected to an outlet of the first compartment and a second end, and a used liquid circuit having a drain pipe connected to an outlet of the second compartment. The method involves the closing of the blood circuit on itself. The blood circuit includes the arterial pipe, the first compartment of the blood treatment apparatus, and the venous pipe, in order to form a closed loop circuit after the arterial and venous pipes have been disconnected from the vascular system of the patient. The blood circuit contains a liquid, which is transferred from the closed loop circuit into the used liquid circuit. The liquid transferred into the used liquid circuit is then drained using the drain pipe.

摘要翻译： 一种在中断治疗会话后排空体外血液处理装置的血液回路的方法。 该装置具有血液处理装置，其具有由半透膜隔开的第一和第二隔室，连接到第一隔室的入口的动脉管，连接到第一隔室的出口的静脉管和第二端， 液体回路具有连接到第二隔室的出口的排放管。 该方法涉及自身闭合血液回路。 血液回路包括动脉管，血液处理装置的第一隔室和静脉管，以便在动脉和静脉管与患者的血管系统断开之后形成闭环回路。 血液回路包含液体，其从闭环回路传送到使用过的液体回路中。 然后使用排水管排出转移到废液回路中的液体。

公开(公告)号：US06966979B2

公开(公告)日：2005-11-22

申请号：US10772340

申请日：2004-02-06

申请人： Renato Pedrazzi

发明人： Renato Pedrazzi

IPC分类号： A61M1/16 ,  A61M1/34 ,  A61M1/36 ,  A61M39/28 ,  B01D61/00 ,  B01D65/00

CPC分类号： A61M1/342 ,  A61M1/1607 ,  A61M1/1609 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3669 ,  A61M39/28 ,  A61M2230/30

摘要： An infusion control device controls infusion of a liquid in an extracorporeal blood circuit having an arterial pipe connected to an inlet of a blood compartment of a filter and a venous pipe connected to an outlet of the blood compartment. The arterial pipe is also connected to a pre-dilution pipe of an infusion circuit, and the venous pipe is also connected to a post-dilution pipe of said infusion circuit. The infusion control device regulates and distributes an infusion flow rate in the arterial and venous pipes based on a monitoring of quantities that are directly correlated with the operating conditions of the filter.

摘要翻译： 输液控制装置控制在体外血液循环中的液体输注，其具有连接到过滤器的血液室的入口的动脉管和连接到血液室的出口的静脉管。 动脉管还连接到输注电路的预稀释管，静脉管也连接到所述输注电路的后稀释管。 输液控制装置基于与过滤器的操作条件直接相关的量的监测来调节和分配动脉和静脉管中的输注流速。