利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.014 秒)

    DESMOSTEROL-PRODUCING YEAST STRAINS AND USES THEREOF
    3.
    发明申请
    DESMOSTEROL-PRODUCING YEAST STRAINS AND USES THEREOF 有权
    生产木霉素的YEAST菌株及其用途

    公开(公告)号：US20120276586A1

    公开(公告)日：2012-11-01

    申请号：US13479355

    申请日：2012-05-24

    申请人： Denis POMPON ,  Bruno DUMAS ,  Roberto SPAGNOLI

    发明人： Denis POMPON ,  Bruno DUMAS ,  Roberto SPAGNOLI

    IPC分类号： C12N1/19 ,  C12P33/00

    CPC分类号： A61K51/0493 ,  C07B2200/05 ,  C12P33/00

    摘要： The invention concerns the production of cholesterol of the Fungi kingdom. More particularly, the invention concerns genetically modified Fungus independently producing cholesterol from a simple carbon source. The invention also concerns the use of the inventive Fungus for producing non-marked and marked cholesterol.

    摘要翻译： 本发明涉及真菌王国的胆固醇生产。 更具体地说，本发明涉及从简单碳源独立生产胆固醇的转基因真菌。 本发明还涉及本发明的真菌用于产生未标记和显着的胆固醇的用途。

    3-O-Oleandrosyl-5-O-desosaminyl erythronolide compounds
    4.
    发明授权
    3-O-Oleandrosyl-5-O-desosaminyl erythronolide compounds 失效
    3-O-奥兰德酰基-5-O-脱氨基甲酰基红新丝菌素化合物

    公开(公告)号：US4429115A

    公开(公告)日：1984-01-31

    申请号：US338117

    申请日：1982-01-08

    申请人： Leonardo M. Cappelletti ,  Roberto Spagnoli ,  Luciano Toscano

    发明人： Leonardo M. Cappelletti ,  Roberto Spagnoli ,  Luciano Toscano

    IPC分类号： C12N1/20 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C12P19/62 ,  C12R1/465 ,  A61K31/71

    CPC分类号： C07H17/08 ,  C12P19/62 ,  C12R1/48 ,  Y10S435/888

    摘要： The fermentation of a substrate selected among erythronolide B, erythronolide A and erythronolide A oxime with a novel mutant, Streptomyces antibioticus ATCC 31771, obtained from an industrial stock for the production of oleandomycin, said novel mutant being incapable of producing the same oleandomycin, permits novel macrolide antibiotics to be produced, having not only an activity range like that of erythromycin, but characterized by a greater stability in acidic environment, whereby for the administration of antibiotic it is no longer necessary to have recourse to esters and/or salts highly toxic for the organism.

    摘要翻译： 选自赤藓酮ide内酯B，赤藓酮酸苷A和赤藓酮ide ide肟的底物的发酵与获自木兰霉素的工业原料获得的新型突变体Streptomyces抗生素链霉菌ATCC 31771的所述新型突变体不能产生相同的夹竹桃霉素，允许新颖的 大环内酯类抗生素不仅具有类似于红霉素的活性范围，而且在酸性环境中具有较高的稳定性，因此为了施用抗生素，不再需要对于高毒性的酯和/或盐 有机体。

    Streptomyces antibioticus ATCC 31771 and process for obtaining same
    10.
    发明授权
    Streptomyces antibioticus ATCC 31771 and process for obtaining same 失效
    链霉菌抗生素ATCC 31771及其获得的方法

    公开(公告)号：US4560662A

    公开(公告)日：1985-12-24

    申请号：US548323

    申请日：1983-11-03

    申请人： Leonardo M. Cappelletti ,  Roberto Spagnoli ,  Luciano Toscano

    发明人： Leonardo M. Cappelletti ,  Roberto Spagnoli ,  Luciano Toscano

    IPC分类号： C12N1/20 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C12P19/62 ,  C12R1/465 ,  C12R1

    CPC分类号： C07H17/08 ,  C12P19/62 ,  C12R1/48 ,  Y10S435/888

    摘要： The fermentation of a substrate selected among erythronolide B, erythronolide A and erythronolide A oxime with a novel mutant, Streptomyces antibioticus ATCC 31771, obtained from an industrial stock for the production of oleandomycin, said novel mutant being incapable of producing the same oleandomycin, permits novel macrolide antibiotics to be produced, having not only an activity range like that of erythromycin, but characterized by a greater stability in acidic environment, whereby for the administration of the antibiotic it is no longer necessary to have recourse to esters and/or salts highly toxic for the organism.

    摘要翻译： 选自赤藓酮ide内酯B，赤藓酮酸苷A和赤藓酮ide ide肟的底物的发酵与获自木兰霉素的工业原料获得的新型突变体Streptomyces抗生素链霉菌ATCC 31771的所述新型突变体不能产生相同的夹竹桃霉素，允许新颖的 大环内酯类抗生素不仅具有红霉素的活性范围，而且在酸性环境中具有更大的稳定性，因此对于抗生素的施用，不再需要追求高毒性的酯和/或盐 为生物体。