公开(公告)号：US20200211688A1

公开(公告)日：2020-07-02

申请号：US16729054

申请日：2019-12-27

申请人： Xing-liang Liu ,  Douglas Ry Wagner

发明人： Xing-liang Liu ,  Douglas Ry Wagner

IPC分类号： G16H20/10 ,  A61K31/05 ,  A61K31/352 ,  G16B20/20

摘要： Methods and systems for providing a personalized cannabinoid treatment regimen to a patient include obtaining genotypes of single nucleotide polymorphisms (SNPs) from a patient's genetic test and modifying base values, such as base dosages or base ratios, using weighting values reflecting the obtained genotypes to obtain regimen values for treating the patient. The regimen values take into account expected responses to cannabinoids based on patient genetic information.

公开(公告)号：US08568798B2

公开(公告)日：2013-10-29

申请号：US13262456

申请日：2009-05-04

申请人： Mylavarapu Venkatramesh ,  D. Ry Wagner ,  Sonia Lall ,  Frederic Y. Lejard ,  Sung-Yong H. Yoon

发明人： Mylavarapu Venkatramesh ,  D. Ry Wagner ,  Sonia Lall ,  Frederic Y. Lejard ,  Sung-Yong H. Yoon

IPC分类号： A61K36/00 ,  C12N5/00

CPC分类号： A01H4/001

摘要： Provided herein are methods of making cocoa polyphenol preparations, which methods comprises harvesting cocoa polyphenols, for example, procyanidins, from the cell suspension culture. In examples of these methods, the resultant cocoa polyphenol preparation is substantially (or in some cases, completely) free of detectable caffeine and theobromine, and more generally substantially free of xanthine alkaloids. Methods of producing a cell suspension culture of cacao cells are also described, including cell suspension cultures useful for making cocoa polyphenol and, more specifically, procyanidin preparations. Theobroma and Herrania sp cell suspension cultures and cocoa polyphenol preparations made therefrom are also provided, in particular xanthine alkaloid-free (or caffeine- and/or theobromine-free) cocoa polyphenol preparations.

摘要翻译： 本文提供制备可可多元酚制剂的方法，该方法包括从细胞悬浮培养物中收获可可多元酚，例如原花青素。 在这些方法的实例中，所得到的可可多酚制剂基本上（或在一些情况下完全不含可检测的咖啡因和可可碱），更通常基本上不含黄嘌呤生物碱。 还描述了产生可可细胞的细胞悬浮培养物的方法，包括可用于制备可可多元酚的细胞悬浮培养物，更具体地，原花青素制剂。 还提供了由本发明制备的可可和Herrania sp细胞悬浮培养物和可可多酚制剂，特别是不含黄嘌呤生物碱的（或咖啡因和/或可可碱）可可多酚制剂。

公开(公告)号：US08222485B2

公开(公告)日：2012-07-17

申请号：US12304343

申请日：2007-06-13

申请人： D. Ry Wagner ,  Shoshan Haran

发明人： D. Ry Wagner ,  Shoshan Haran

IPC分类号： A01H5/00 ,  A01H5/10 ,  C12N15/09 ,  C12N15/82

CPC分类号： C12N15/8285 ,  C07K14/415 ,  Y02A40/164

摘要： The present disclosure is directed to plants that display a modified pathogen resistance phenotype (e.g., increased nematode resistance) due to altered expression of an NMR nucleic acid. The invention is further directed to methods of generating plants with a modified pathogen resistance phenotype.

摘要翻译： 本公开涉及由于NMR核酸的表达改变而显示修饰的病原体抗性表型（例如增加的线虫抗性）的植物。 本发明进一步涉及产生具有修饰的病原体抗性表型的植物的方法。

公开(公告)号：US20120090050A1

公开(公告)日：2012-04-12

申请号：US13328782

申请日：2011-12-16

申请人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

发明人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

IPC分类号： A01H5/00 ,  C12N15/82 ,  A01H5/10

CPC分类号： C12N15/8255 ,  C07K14/415 ,  C12N15/8201 ,  C12N15/8242 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8251 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype.

公开(公告)号：US20110318473A1

公开(公告)日：2011-12-29

申请号：US13221790

申请日：2011-08-30

申请人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

发明人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

IPC分类号： A23L1/10 ,  A01H5/10 ,  A01H1/00 ,  A01H5/00

CPC分类号： C12N15/8246 ,  C07K14/415 ,  C12N15/8201 ,  C12N15/8241 ,  C12N15/8251 ,  C12N15/8255 ,  C12N15/8261 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156 ,  C12Q2600/16 ,  Y02A40/146

摘要： The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype.

公开(公告)号：US20080213457A1

公开(公告)日：2008-09-04

申请号：US11940248

申请日：2007-11-14

申请人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

发明人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

IPC分类号： A23K1/14 ,  A01H5/00 ,  C12N15/29 ,  A01H1/02

CPC分类号： C12N15/8255 ,  C07K14/415 ,  C12N15/8201 ,  C12N15/8242 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8251 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype.

公开(公告)号：US20080127374A1

公开(公告)日：2008-05-29

申请号：US11940284

申请日：2007-11-14

申请人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

发明人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

IPC分类号： A01H1/00 ,  C12N15/87

CPC分类号： C12N15/8251 ,  A01H3/00 ,  A01H5/00 ,  A23K10/30 ,  A23L7/198 ,  A23L19/00 ,  A23V2002/00 ,  C07K14/415 ,  C12N15/8245 ,  C12N15/8246 ,  C12N15/8247

摘要： The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype.

摘要翻译： 本发明涉及由于IMQ核酸的表达改变而显示改善的油量表型或改善的膳食质量表型的植物。 本发明进一步涉及产生具有改善的油量表型或改良的膳食质量表型的植物的方法。

公开(公告)号：US20050204424A1

公开(公告)日：2005-09-15

申请号：US11109077

申请日：2005-04-18

申请人： Ry Wagner ,  Karen Hicks ,  Michelle Spence ,  Henriette Foss ,  Xiang Liu ,  Michael Covington

发明人： Ry Wagner ,  Karen Hicks ,  Michelle Spence ,  Henriette Foss ,  Xiang Liu ,  Michael Covington

IPC分类号： A01H5/00 ,  C07H21/02 ,  C07K14/415 ,  C12N1/21 ,  C12N5/10 ,  C12N15/00 ,  C12N15/29 ,  C12N15/82 ,  A01H1/00

CPC分类号： C12N15/8261 ,  C07K14/415 ,  C12N15/8237 ,  C12N15/827 ,  Y02A40/146

摘要： Nucleic acid molecules that encode plant proteins involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic and/or circadian clock-based gene expression of the plants.

摘要翻译： 公开了编码涉及光周期和昼夜节律的植物蛋白质的核酸分子。 这些分子可以被引入植物中，以便改变植物的光周期和/或昼夜节律基于时钟的基因表达。

公开(公告)号：US06433251B1

公开(公告)日：2002-08-13

申请号：US09513057

申请日：2000-02-24

申请人： D. Ry Wagner ,  Karen A. Hicks ,  Michelle Z. Spence ,  Henriette Foss ,  Xing Liang Liu ,  Michael F. Covington

发明人： D. Ry Wagner ,  Karen A. Hicks ,  Michelle Z. Spence ,  Henriette Foss ,  Xing Liang Liu ,  Michael F. Covington

IPC分类号： A01H500

CPC分类号： C12N15/8261 ,  C07K14/415 ,  C12N15/8237 ,  C12N15/827 ,  Y02A40/146

摘要： Nucleic acid molecules that encode a plant promoter involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic and/or circadian clock-based gene expression of the plants.

摘要翻译： 公开了编码参与光周期和昼夜节律的植物启动子的核酸分子。 这些分子可以被引入植物中，以便改变植物的光周期和/或昼夜节律基于时钟的基因表达。

公开(公告)号：US08030541B2

公开(公告)日：2011-10-04

申请号：US11940269

申请日：2007-11-14

申请人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

发明人： John P. Davies ,  Hein Tsoeng (Medard) Ng ,  D. Ry Wagner

IPC分类号： C12N15/82 ,  C12N15/09 ,  C12N15/29 ,  A01H5/00

CPC分类号： C12N15/8247 ,  A23L25/30 ,  C07K14/415 ,  C12N15/8245 ,  C12N15/8251 ,  C12N15/8255 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of an IMQ nucleic acid. The invention is further directed to methods of generating plants with an improved oil quantity phenotype or improved meal quality phenotype.

摘要翻译： 本发明涉及由于IMQ核酸的表达改变而显示改善的油量表型或改善的膳食质量表型的植物。 本发明进一步涉及产生具有改善的油量表型或改良的膳食质量表型的植物的方法。