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公开(公告)号：US20110230745A1
公开(公告)日：2011-09-22
申请号：US12725865
申请日：2010-03-17
IPC分类号： A61B5/04 , A61B5/0476
CPC分类号： A61B5/0408 , A61B5/0428 , A61B5/685 , A61B5/721 , A61B2562/0219 , A61B2562/028 , A61B2562/125
摘要： An electrode system for the measurement of biopotential signals includes a substrate. A microelectrode is coupled to the substrate. An accelerometer is coupled to the substrate. A biopotential amplifier is electrically coupled to the microelectrode and acceleration measurement circuit is electrically coupled to the accelerometer. A method of measuring a biopotential from a patient includes sensing a biopotential with a microelectrode. The biopotential is amplified with an amplifier in electrical communication with the microelectrode. A movement of the electrode is sensed with an accelerometer integrated with the electrode substrate. The sensed biopotential and the sensed movement are provided to an electronic controller. Portions of the sensed biopotential that correspond to sensed movement are identified as artifact contaminated portions.
摘要翻译： 用于测量生物电位信号的电极系统包括基底。 微电极耦合到衬底。 加速度传感器耦合到基板。 生物电位放大器电耦合到微电极，并且加速度测量电路电耦合到加速度计。 从患者测量生物潜力的方法包括用微电极感测生物电位。 生物电位用与微电极电连通的放大器放大。 用与电极基板一体化的加速度计感测电极的移动。 感测到的生物电势和感测的运动被提供给电子控制器。 对应于感测到的移动的感测生物电位的部分被识别为伪影污染部分。
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公开(公告)号：US20080204743A1
公开(公告)日：2008-08-28
申请号：US12104471
申请日：2008-04-17
申请人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
发明人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J1/44 , G01J3/02 , G01J3/0229 , G01J3/0232 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0297 , G01J3/1895 , G01J3/4338 , G02B26/04 , H01L31/107
摘要： A method of Raman detection for a portable, integrated spectrometer instrument includes directing Raman scattered photons by a sample to an avalanche photodiode (APD), the APD configured to generate an output signal responsive to the intensity of the Raman scattered photons incident thereon. The output signal of the APD is amplified and passed through a discriminator so as to reject at least one or more of amplifier noise and dark noise. A number of discrete output pulses within a set operational range of the discriminator is counted so as to determine a number of photons detected by the APD.
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公开(公告)号：US20070236697A1
公开(公告)日：2007-10-11
申请号：US11400948
申请日：2006-04-10
申请人： Anis Zribi , Stacey Kennerly , Glenn Claydon , Long Que , Ayan Banerjee , Shankar Chandrasekaran , Shivappa Goravar , David Hays
发明人： Anis Zribi , Stacey Kennerly , Glenn Claydon , Long Que , Ayan Banerjee , Shankar Chandrasekaran , Shivappa Goravar , David Hays
CPC分类号： G01J3/02 , G01J3/0208 , G01J3/0256 , G01J3/0272 , G01J3/0291 , G01J3/26 , G01J3/44 , G01N21/65 , G01N21/658 , G01N2201/0221
摘要： An integrated spectrometer instrument, including an optical source formed on a chip, the optical source configured to generate an incident optical beam upon a sample to be measured. Collection optics formed on the chip are configured to receive a scattered optical beam from the sample, and filtering optics formed on the chip are configured to remove elastically scattered light from the scattered optical beam at a wavelength corresponding to the optical source. A tunable filter formed on the chip is configured to pass selected wavelengths of the scattered optical beam, and a photo detector device formed on the chip is configured to generate an output signal corresponding to the intensity of photons passed through the tunable filter.
摘要翻译： 一种集成光谱仪器，包括形成在芯片上的光源，所述光源被配置为在待测样品上产生入射光束。 形成在芯片上的采集光学元件被配置为接收来自样品的散射光束，并且形成在芯片上的滤光光学元件被配置为以对应于光源的波长去除来自散射光束的弹性散射光。 形成在芯片上的可调滤波器被配置为通过散射光束的选定波长，并且形成在芯片上的光检测器装置被配置为产生对应于通过可调谐滤波器的光子的强度的输出信号。
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4.发明申请Collection probe for use in a Raman spectrometer system and methods of making and using the same 有权用于拉曼光谱仪系统的收集探针及其制作和使用方法公开(公告)号：US20070127019A1
公开(公告)日：2007-06-07
申请号：US11400863
申请日：2006-04-10
申请人： Anis Zribi , Ayan Banerjee , Shivappa Goravar , Shankar Chandrasekaran , Sandip Maity , Glenn Claydon , Stacey Kennerly , Todd Tolliver , David Hays , Sheila Tandon , Long Que , Christopher Keimel
发明人： Anis Zribi , Ayan Banerjee , Shivappa Goravar , Shankar Chandrasekaran , Sandip Maity , Glenn Claydon , Stacey Kennerly , Todd Tolliver , David Hays , Sheila Tandon , Long Que , Christopher Keimel
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0291 , G01N21/65
摘要： A photonic crystal based collection probe is provided. The probe includes a photonic crystal configured to guide and condition a beam of Raman scattered photons. Further, the device includes a spectrograph in optical communication with the photonic crystal and configured to receive Raman scattering from the photonic crystal. The device may be employed in a Raman spectrometer system.
摘要翻译： 提供了一种基于光子晶体的收集探针。 探针包括配置成引导和调节拉曼散射光子束的光子晶体。 此外，该装置包括与光子晶体光学通信并被配置为从光子晶体接收拉曼散射的光谱仪。 该装置可以用在拉曼光谱仪系统中。
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公开(公告)号：US07551287B2
公开(公告)日：2009-06-23
申请号：US11502186
申请日：2006-08-10
申请人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjec
发明人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjec
摘要： According to one embodiment, a micro-electrical mechanical system apparatus includes a bi-stable actuator and at least one movable Fabry-Perot filter cavity mirror coupled to the bi-stable actuator. The bi-stable actuator may be associated with a first latched position and a second latched position and may comprise, for example, a thermal device, an electrostatic device (e.g., a parallel plate or comb drive), or a magnetic device. According to some embodiments, a relationship between a voltage applied to an actuator of a Fabry-Perot filter and an amount of displacement associated with a movable mirror is substantially linear.
摘要翻译： 根据一个实施例，微电机械系统装置包括耦合到双稳态致动器的双稳态致动器和至少一个可移动的法布里 - 珀罗滤波器腔镜。 双稳态致动器可以与第一锁定位置和第二锁定位置相关联，并且可以包括例如热装置，静电装置（例如，平行板或梳驱动器）或磁性装置。 根据一些实施例，施加到法布里 - 珀罗滤波器的致动器的电压与与可移动镜相关联的位移量之间的关系基本上是线性的。
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6.发明申请METHOD AND APPARATUS FOR IMPROVED SIGNAL TO NOISE RATIO IN RAMAN SIGNAL DETECTION FOR MEMS BASED SPECTROMETERS 失效用于基于MEMS的光谱仪的拉曼信号检测中改进信号噪声比的方法和装置公开(公告)号：US20080018890A1
公开(公告)日：2008-01-24
申请号：US11459449
申请日：2006-07-24
申请人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
发明人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J1/44 , G01J3/02 , G01J3/0229 , G01J3/0232 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0297 , G01J3/1895 , G01J3/4338 , G02B26/04 , H01L31/107
摘要： A method of Raman detection for a portable, integrated spectrometer instrument includes directing Raman scattered photons by a sample to an avalanche photodiode (APD), the APD configured to generate an output signal responsive to the intensity of the Raman scattered photons incident thereon. The output signal of the APD is amplified and passed through a discriminator so as to reject at least one or more of amplifier noise and dark noise. A number of discrete output pulses within a set operational range of the discriminator is counted so as to determine a number of photons detected by the APD.
摘要翻译： 用于便携式，集成光谱仪器的拉曼检测方法包括将样品的拉曼散射光子引导到雪崩光电二极管（APD），APD被配置为响应入射在其上的拉曼散射光子的强度产生输出信号。 APD的输出信号被放大并通过鉴频器，以便抑制至少一个或多个放大器噪声和暗噪声。 对鉴别器的设定操作范围内的多个离散输出脉冲进行计数，以便确定APD检测到的光子数量。
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公开(公告)号：US08229537B2
公开(公告)日：2012-07-24
申请号：US12725865
申请日：2010-03-17
IPC分类号： A61B5/04 , A61B5/0478 , A61B5/11
CPC分类号： A61B5/0408 , A61B5/0428 , A61B5/685 , A61B5/721 , A61B2562/0219 , A61B2562/028 , A61B2562/125
摘要： An electrode system for the measurement of biopotential signals includes a substrate. A microelectrode is coupled to the substrate. An accelerometer is coupled to the substrate. A biopotential amplifier is electrically coupled to the microelectrode and acceleration measurement circuit is electrically coupled to the accelerometer. A method of measuring a biopotential from a patient includes sensing a biopotential with a microelectrode. The biopotential is amplified with an amplifier in electrical communication with the microelectrode. A movement of the electrode is sensed with an accelerometer integrated with the electrode substrate. The sensed biopotential and the sensed movement are provided to an electronic controller. Portions of the sensed biopotential that correspond to sensed movement are identified as artifact contaminated portions.
摘要翻译： 用于测量生物电位信号的电极系统包括基底。 微电极耦合到衬底。 加速度传感器耦合到基板。 生物电位放大器电耦合到微电极，加速度测量电路电耦合到加速度计。 从患者测量生物潜力的方法包括用微电极感测生物电位。 生物电位用与微电极电连通的放大器放大。 用与电极基板一体化的加速度计感测电极的移动。 感测到的生物电势和感测的运动被提供给电子控制器。 对应于感测到的移动的感测生物电位的部分被识别为伪影污染部分。
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8.发明授权Irregularly shaped actuator fingers for a micro-electromechanical system fabry-perot filter 失效用于微机电系统fabry-perot过滤器的不规则形状的执行器指公开(公告)号：US07796269B2
公开(公告)日：2010-09-14
申请号：US11502187
申请日：2006-08-10
申请人： Anis Zribi , Glenn S. Claydon , Long Que , Stacey Kennerly , Shankar Chandrasekaran , Shivappa Goravar , David C. Hays , Ayan Banerjee
发明人： Anis Zribi , Glenn S. Claydon , Long Que , Stacey Kennerly , Shankar Chandrasekaran , Shivappa Goravar , David C. Hays , Ayan Banerjee
IPC分类号： G01J3/45
CPC分类号： G01J3/26 , G01J3/06 , G02B26/001
摘要： According to one embodiment, a micro-electrical mechanical system apparatus includes (i) a comb drive actuator having at least one irregularly shaped finger and (ii) a movable Fabry-Perot filter cavity mirror coupled to the comb drive actuator. According to some embodiments, a relationship between a voltage applied to the comb drive actuator and an amount of displacement associated with the movable mirror is substantially linear.
摘要翻译： 根据一个实施例，微电机械系统装置包括（i）具有至少一个不规则形状的指状物的梳状驱动致动器和（ii）耦合到梳状驱动致动器的可移动的法布里 - 珀罗滤光镜反射镜。 根据一些实施例，施加到梳状驱动致动器的电压与与可移动镜相关联的位移量之间的关系基本上是线性的。
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公开(公告)号：US07586602B2
公开(公告)日：2009-09-08
申请号：US11459449
申请日：2006-07-24
申请人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
发明人： Sandip Maity , Ayan Banerjee , Anis Zribi , Stacey Kennerly , Long Que , Glenn Claydon , Shankar Chandrasekaran , Shivappa Goravar
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , G01J1/44 , G01J3/02 , G01J3/0229 , G01J3/0232 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0286 , G01J3/0297 , G01J3/1895 , G01J3/4338 , G02B26/04 , H01L31/107
摘要： A method of Raman detection for a portable, integrated spectrometer instrument includes directing Raman scattered photons by a sample to an avalanche photodiode (APD), the APD configured to generate an output signal responsive to the intensity of the Raman scattered photons incident thereon. The output signal of the APD is amplified and passed through a discriminator so as to reject at least one or more of amplifier noise and dark noise. A number of discrete output pulses within a set operational range of the discriminator is counted so as to determine a number of photons detected by the APD.
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公开(公告)号：US20100220331A1
公开(公告)日：2010-09-02
申请号：US11447779
申请日：2006-06-06
申请人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjee
发明人： Anis Zribi , Glenn S. Claydon , David C. Hays , Stacey Kennerly , Long Que , Shankar Chandrasekaran , Shivappa Goravar , Ayan Banerjee
CPC分类号： G01J3/26 , G01J3/06 , G02B26/001
摘要： According to some embodiments, a micro-electrical mechanical system apparatus includes an actuator within a plane and at least one movable mirror oriented substantially normal to the plane. The actuator may move the movable mirror with respect to a fixed mirror oriented substantially normal to the plane and substantially parallel to the movable mirror. The space between the fixed and movable mirrors might comprise, for example, a Fabry-Perot filter cavity for a spectrometer.
摘要翻译： 根据一些实施例，微电机械系统装置包括在平面内的致动器和基本上垂直于该平面定向的至少一个可移动镜。 致动器可以相对于基本上垂直于平面定向并且基本上平行于可移动镜的固定镜移动可移动镜。 固定镜和可移动镜之间的空间可以包括例如用于光谱仪的法布里 - 珀罗滤光腔。
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