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1.发明授权System for integrated analysis of real-time polymerase chain reaction and DNA chip and method for integrated analysis using the same 有权用于实时聚合酶链反应和DNA芯片的综合分析系统及其综合分析方法公开(公告)号：US09551038B2
公开(公告)日：2017-01-24
申请号：US13554348
申请日：2012-07-20
Applicant: Sung-Min Seo , Do-Bu Lee , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
Inventor： Sung-Min Seo , Do-Bu Lee , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
CPC classification number: C12Q1/6888 , B01L3/50825 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2300/046 , B01L2300/0636 , B01L2300/0663 , B01L2300/0829 , B01L2300/0851 , C12Q1/686 , C12Q1/689 , C12Q1/706 , C12Q2561/113 , C12Q2565/501
Abstract: Provided are a system for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same, and more particularly to an apparatus for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same. According to the method for integrated analysis of a biomaterial of the present invention, gene amplification proceeds and subsequently hybridization proceeds in a single reactor, thereby preventing contamination of the sample due to external factors, which may be caused while the sample is transferred for reaction, and automating a series of procedures such as injection of the sample, reaction of the biomaterial, and detection and analysis of results.
Abstract translation: 提供了一种用于实时聚合酶链反应和DNA芯片的综合分析的系统以及使用其的综合分析方法，更具体地涉及用于实时聚合酶链反应和DNA芯片的综合分析的装置 以及使用该方法进行综合分析的方法。 根据本发明的生物材料的综合分析方法，进行基因扩增，随后在单个反应器中进行杂交，从而防止样品由于在将样品转移反应而引起的外部因素的污染， 并自动化一系列程序，如注射样品，生物材料的反应，以及检测和分析结果。
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公开(公告)号：US08871160B2
公开(公告)日：2014-10-28
申请号：US13554504
申请日：2012-07-20
Applicant: Sung-Min Seo , Jae-Hyung Park , Oleksandrov Sergiy , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
Inventor： Sung-Min Seo , Jae-Hyung Park , Oleksandrov Sergiy , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
CPC classification number: B01L3/50853 , B01L3/50825 , B01L2200/025 , B01L2300/046 , B01L2300/0609 , B01L2300/0636
Abstract: Provided is a biomaterial detecting device for confirming or detecting a biomaterial reaction, and more particularly to a biomaterial detecting device, which is formed in a stick type to thereby be immersed in a tube containing a biomaterial solution to be tested; has an upper portion with a cap structure to thereby induce reaction with a biomaterial, and thus facilitate confirmation and detection of the biomaterial; and is formed in a cap structure to thereby prevent evaporation of a sample and infiltration of an external material at the time of a biomaterial reaction in the tube, and thus improve reliability in analysis.
Abstract translation: 提供一种用于确认或检测生物材料反应的生物材料检测装置，更具体地说，涉及一种生物材料检测装置，其以棒状形式形成，从而浸入含有待测试的生物材料溶液的管中; 具有帽结构的上部，从而诱导与生物材料的反应，从而促进生物材料的确认和检测; 并且形成为帽结构，从而防止样品的蒸发和管中的生物材料反应时的外部材料的渗透，从而提高分析的可靠性。
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公开(公告)号：US20130225445A1
公开(公告)日：2013-08-29
申请号：US13554170
申请日：2012-07-20
Applicant: Sung-Min SEO , Jae-Hyung PARK , Sergiy Oleksandrov , Joong Hwan LEE , Mun·Cheol PAEK , Su-Jin KU
Inventor： Sung-Min SEO , Jae-Hyung PARK , Sergiy Oleksandrov , Joong Hwan LEE , Mun·Cheol PAEK , Su-Jin KU
CPC classification number: B01L3/50851 , B01L7/52 , B01L2200/12 , B01L2200/142 , B01L2300/04 , B01L2300/0636 , B01L2300/0829 , B01L2300/0851 , B01L2300/16
Abstract: Provided is a bio-reaction device chip for confirming or detecting a biomaterial reaction, and more particularly, is a bio-reaction device chip, where a plurality of wells are formed in the plate to contain biomaterials to be tested, thereby simultaneously analyzing various targets, and the well is formed to have a structure of two or more steps such that the sample to be tested is contained in the lower well and a protective layer for protecting the sample, such as oil, is contained in the upper well, thereby preventing evaporation of the sample due to heating at the time of the biomaterial reaction, and thus, improving reliability in analysis.
Abstract translation: 本发明提供一种用于确认或检测生物材料反应的生物反应装置芯片，更具体地，是生物反应装置芯片，其中在板中形成多个孔以容纳待测试的生物材料，从而同时分析各种靶 形成为具有两个以上的步骤的结构，使得待测试样品包含在下部井中，并且用于保护样品（例如油）的保护层被包含在上部井中，从而防止 在生物材料反应时由于加热而使样品蒸发，从而提高分析的可靠性。
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公开(公告)号：US20130225453A1
公开(公告)日：2013-08-29
申请号：US13554504
申请日：2012-07-20
Applicant: Sung-Min SEO , Jae-Hyung Park , Oleksandrov Sergiy , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
Inventor： Sung-Min SEO , Jae-Hyung Park , Oleksandrov Sergiy , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
CPC classification number: B01L3/50853 , B01L3/50825 , B01L2200/025 , B01L2300/046 , B01L2300/0609 , B01L2300/0636
Abstract: Provided is a biomaterial detecting device for confirming or detecting a biomaterial reaction, and more particularly to a biomaterial detecting device, which is formed in a stick type to thereby be immersed in a tube containing a biomaterial solution to be tested; has an upper portion with a cap structure to thereby induce reaction with a biomaterial, and thus facilitate confirmation and detection of the biomaterial; and is formed in a cap structure to thereby prevent evaporation of a sample and infiltration of an external material at the time of a biomaterial reaction in the tube, and thus improve reliability in analysis.
Abstract translation: 提供一种用于确认或检测生物材料反应的生物材料检测装置，更具体地说，涉及一种生物材料检测装置，其以棒状形式形成，从而浸入含有待测试的生物材料溶液的管中; 具有帽结构的上部，从而诱导与生物材料的反应，从而促进生物材料的确认和检测; 并且形成为帽结构，从而防止样品的蒸发和管中的生物材料反应时的外部材料的渗透，从而提高分析的可靠性。
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公开(公告)号：US06409830B1
公开(公告)日：2002-06-25
申请号：US09585019
申请日：2000-06-01
Applicant: Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
Inventor： Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
IPC: C30B2500
CPC classification number: C23C16/40
Abstract: An organometallic compound of formula LiOR′.(R′O)MR2 is vaporized at a low temperature and employed in a CVD process of a heterometallic oxide film of the LiMO2 type, wherein M is a Group 13 element such as Al or Ga; R is a C1-10 alkyl group; and R′ is a C2-10 alkyl group.
Abstract translation: 式（R'O）MR2的有机金属化合物在低温下蒸发并用于LiMO2型异金属氧化物膜的CVD工艺中，其中M是诸如Al或Ga的第13族元素; R为C1-10烷基; 并且R'是C 2-10烷基。
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Patent Agency Ranking6.发明授权Volatile organometallic compound containing a divalent metal and a group 13 metal, process for preparing same, and process for preparing a heterometallic oxide film using same 失效包含二价金属和第13族金属的挥发性有机金属化合物，其制备方法以及使用其制备异金属氧化物膜的方法
公开(公告)号：US5998644A
公开(公告)日：1999-12-07
申请号：US132523
申请日：1998-08-11
Applicant: Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku , Chang-Gyoun Kim , Kyu-Sang Yu
Inventor： Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku , Chang-Gyoun Kim , Kyu-Sang Yu
Abstract: A novel organometallic compound of formula M[(.mu.-OR').sub.2 M'R.sub.2 ].sub.2 can be vaporized at a low temperature and advantageously employed in the CVD of a heterometallic oxide film of the MM'.sub.2 O.sub.4 type, wherein M is a divalent element such as Be, Mg, Zn or Cd; M' is a Group 13 element such as Al or Ga; and R and R' are each independently a C.sub.1-10, alkyl group, with the proviso that if M is Mg, M' is not Al.
Abstract translation: 式M [（-OR'）2M'R2] 2的新型有机金属化合物可以在低温下汽化并有利地用于MM'2O4型异金属氧化物膜的CVD，其中M是二价元素 如Be，Mg，Zn或Cd; M'是诸如Al或Ga的第13族元素; 并且R和R'各自独立地为C 1-10烷基，条件是如果M是Mg，则M'不是Al。
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7.发明授权Process for the preparation of aluminum oxide film using dialkylaluminum alkoxide 失效使用二烷基铝醇盐制备氧化铝膜的方法
公开(公告)号：US5922405A
公开(公告)日：1999-07-13
申请号：US77450
申请日：1998-05-29
Applicant: Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
Inventor： Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
CPC classification number: C23C16/403
Abstract: An aluminum oxide film is economically and conveniently deposited on a substrate by a process which comprises vaporizing a dialkylaluminum alkoxide compound at a temperature ranging from 0 to 25.degree. C. and contacting the resulting vapor with said substrate heated to a temperature ranging from 300 to 600.degree. C.
Abstract translation: PCT No.PCT / KR96 / 00230 Sec。 371日期：1998年5月29日 102（e）日期1998年5月29日PCT提交1996年12月3日PCT公布。 公开号WO97 / 20963 日期：1997年6月12日氧化铝膜经济地方便地通过包括在0至25℃的温度范围内蒸发二烷基铝烷氧化物的方法沉积在基底上，并将所得蒸气与加热到温度 范围从300到600℃
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8.发明授权Volatile magnesium alkylaluminum alkoxide and deposition of magnesium aluminate film using same 失效挥发性镁烷基铝醇盐和铝酸镁膜的沉积使用相同
公开(公告)号：US6063951A
公开(公告)日：2000-05-16
申请号：US125225
申请日：1998-08-11
Applicant: Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
Inventor： Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku
CPC classification number: C23C16/403 , C07F5/06
Abstract: Novel magnesium dialkylaluminum alkoxide derivative represented by Mg[(.mu.--OR').sub.2 AlR.sub.2 ].sub.2 wherein R and R' are each a C.sub.1-5 alkyl group and R is not the same as R', preferably magnesium dimethylaluminum isopropoxide, is easily prepared by reacting a trialkylaluminum with an alcohol or an aluminum trialkoxide to obtain a dialkylaluminum alkoxide; reacting the dialkylaluminium alkoxide with an alkali metal alkoxide to obtain an alkali metal dialkylaluminum alkoxide; and reacting the alkali metal dialkylaluminum alkoxide with a magnesium halide. The alkoxide derivative of the present invention can be vaporized at a low temperature, below 70.degree. C. and, therefore, effectively employed in the CVD process of a magnesium aluminate film.
Abstract translation: PCT No.PCT / KR97 / 00025 Sec。 371日期：1998年8月11日 102（e）日期1998年8月11日PCT提交1997年2月12日PCT公布。 公开号WO97 / 29112 PCT 日期1997年8月14日由Mg [(OR'）2AlR2] 2表示的新型二烷基铝烷醇铝衍生物，其中R和R'各自为C 1-5烷基，R不与R'相同，优选异丙醇二甲基铝 可以通过使三烷基铝与醇或三烷氧基铝反应得到二烷基铝醇盐容易地制备; 使二烷基铝醇盐与碱金属醇盐反应，得到碱金属二烷基铝醇盐; 并使碱金属二烷基铝醇盐与卤化镁反应。 本发明的醇盐衍生物可以在低于70℃的低温下汽化，因此有效地用于铝酸镁膜的CVD工艺中。
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9.发明申请SYSTEM FOR INTEGRATED ANALYSIS OF REAL-TIME POLYMERASE CHAIN REACTION AND DNA CHIP AND METHOD FOR INTEGRATED ANALYSIS USING THE SAME 有权用于实时聚合酶链反应和DNA芯片的综合分析系统及其综合分析方法公开(公告)号：US20130303390A1
公开(公告)日：2013-11-14
申请号：US13554348
申请日：2012-07-20
Applicant: Sung-Min Seo , Do-Bu Lee , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
Inventor： Sung-Min Seo , Do-Bu Lee , Joong Hwan Lee , Mun-Cheol Paek , Su-Jin Ku
CPC classification number: C12Q1/6888 , B01L3/50825 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2300/046 , B01L2300/0636 , B01L2300/0663 , B01L2300/0829 , B01L2300/0851 , C12Q1/686 , C12Q1/689 , C12Q1/706 , C12Q2561/113 , C12Q2565/501
Abstract: Provided are a system for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same, and more particularly to an apparatus for integrated analysis of a real-time polymerase chain reaction and a DNA chip and a method for integrated analysis using the same. According to the method for integrated analysis of a biomaterial of the present invention, gene amplification proceeds and subsequently hybridization proceeds in a single reactor, thereby preventing contamination of the sample due to external factors, which may be caused while the sample is transferred for reaction, and automating a series of procedures such as injection of the sample, reaction of the biomaterial, and detection and analysis of results.
Abstract translation: 提供了一种用于实时聚合酶链反应和DNA芯片的综合分析的系统以及使用其的综合分析方法，更具体地涉及用于实时聚合酶链反应和DNA芯片的综合分析的装置 以及使用该方法进行综合分析的方法。 根据本发明的生物材料的综合分析方法，进行基因扩增，随后在单个反应器中进行杂交，从而防止样品由于在将样品转移反应而引起的外部因素的污染， 并自动化一系列程序，如注射样品，生物材料的反应，以及检测和分析结果。
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10.发明授权Volatile organometallic compound containing a divalent metal and a group 13 metal, process for preparing same, and process for preparing a heterometallic oxide film using same 失效包含二价金属和第13族金属的挥发性有机金属化合物，其制备方法以及使用其制备异金属氧化物膜的方法
公开(公告)号：US06156916A
公开(公告)日：2000-12-05
申请号：US406571
申请日：1999-09-24
Applicant: Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku , Chang-Gyoun Kim , Kyu-Sang Yu
Inventor： Yun-Soo Kim , Won-Yong Koh , Su-Jin Ku , Chang-Gyoun Kim , Kyu-Sang Yu
Abstract: A novel organometallic compound of formula M[(.mu.-OR').sub.2 M'R.sub.2 ].sub.2 can be vaporized at a low temperature and advantageously employed in the CVD of a heterometallic oxide film of the MM'.sub.2 O.sub.4 type, wherein M is a divalent element such as Be, Mg, Zn or Cd; M' is a Group 13 element such as Al or Ga; and R and R' are each independently a C.sub.1-10 alkyl group, with the proviso that if M is Mg, M' is not Al.
Abstract translation: 式M [（-OR'）2M'R2] 2的新型有机金属化合物可以在低温下汽化并有利地用于MM'2O4型异金属氧化物膜的CVD，其中M是二价元素 如Be，Mg，Zn或Cd; M'是诸如Al或Ga的第13族元素; 并且R和R'各自独立地为C 1-10烷基，条件是如果M是Mg，M'不是Al。
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