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公开(公告)号:US07553865B2
公开(公告)日:2009-06-30
申请号:US10521958
申请日:2003-07-22
申请人: Hiroyuki Shirai , Tatsuya Nakai , Masami Serizawa , Yasuo Shinoda , Toshio Inagi
发明人: Hiroyuki Shirai , Tatsuya Nakai , Masami Serizawa , Yasuo Shinoda , Toshio Inagi
IPC分类号: A61K31/40 , A01N43/38 , C07D209/26
CPC分类号: A61K9/06 , A61K9/0014 , A61K31/405 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38 , A61K47/44
摘要: An object of the present invention is to provide an indomethacin external preparation that has an excellent use feeling and excellent absorbability and causes no phase separation into an oil layer and an aqueous layer, thus exhibiting satisfactory stability of preparation with time. Provided is an indomethacin external preparation containing: 0.1 to 3 wt % of indomethacin; 25 to 50 wt % of alcohol; 0.01 to 5 wt % of gelling agent; 5 to 30 wt % of oil component; 20 to 50 wt % of water; and 0.01 to 10 wt % of one or more components selected from the group consisting of glyceryl monostearate, sorbitan monostearate, stearyl alcohol, and polyethylene glycol monostearate.
摘要翻译: 本发明的目的是提供具有优异的使用感和优异的吸收性的吲哚美辛外用制剂,并且不会使相分离成油层和水层,从而表现出令人满意的制备时间稳定性。 本发明提供消炎痛外用制剂,含有0.1〜3重量%的吲哚美辛; 25〜50重量%的醇; 0.01〜5重量%的胶凝剂; 5〜30重量%的油成分; 20〜50重量%的水; 和0.01〜10重量%的选自单硬脂酸甘油酯,脱水山梨糖醇单硬脂酸酯,硬脂醇和聚乙二醇单硬脂酸酯的一种或多种成分。
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公开(公告)号:US20070166360A1
公开(公告)日:2007-07-19
申请号:US10589247
申请日:2005-03-30
申请人: Tatsuya Nakai , Makoto Kanebako
发明人: Tatsuya Nakai , Makoto Kanebako
IPC分类号: A61K31/401 , A61K31/366 , A61K31/22 , A61F13/02
CPC分类号: A61K31/22 , A61K9/0014 , A61K9/7053 , A61K9/7076 , A61K31/366 , A61K31/40 , A61K31/401 , A61K31/47 , A61K45/06 , A61K47/08 , A61K47/10 , A61K47/12 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要: An external preparation comprising following ingredients (A) and (B): (A) a compound represented by the following general formula (1) wherein R1 represents an organic residue having a cyclic structure that may have a substituent; R2 represents a hydrogen atom or a lower alkyl group; and X represents an ethylene group or an ethenylene group or a salt thereof, and (B) a monoterpene. The external preparation of the present invention is excellent in percutaneous absorbability.
摘要翻译: 包含以下成分(A)和(B)的外用制剂:(A)由以下通式(1)表示的化合物,其中R 1表示具有环状结构的有机残基, 取代基; R 2表示氢原子或低级烷基; X表示亚乙基或亚乙烯基或其盐,(B)单萜。 本发明的外用制剂的经皮吸收性优异。
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公开(公告)号:US4808083A
公开(公告)日:1989-02-28
申请号:US150395
申请日:1988-01-29
IPC分类号: F04C28/10 , F04B49/02 , F04C18/344 , F04C28/14 , F04C29/08
CPC分类号: F04C28/14
摘要: A variable capacity type vane compressor comprising a cylinder having an oblong cylinder bore and a rotor with radial vanes rotatably inserted in the cylinder so that the radially outer ends of the vanes are in slidable contact with the cylinder bore surface to form compression chambers therebetween. A movable capacity control disk is arranged at an interface between one side plate and the rotor to control the quantity of introduced gas and/or returned compressed gas to vary a capacity of the compressor. The capacity control disk is moved by a spool actuator inserted in a spool cylinder having opposed working chambers. Gas under output pressure is introduced into the first working chamber, and oil under output pressure is introduced into the second working chamber, while a leak passage relieves the oil pressure to an intermediate pressure. A spring is also arranged in the second working chamber to urge the spool, and a valve is arranged in the oil passage close to the second working chamber to regulate the movement of the spool in response to a predetermined requirement.
摘要翻译: 一种可变容量型叶片压缩机,包括具有长圆筒孔的圆筒和具有可旋转地插入圆筒中的径向叶片的转子,使得叶片的径向外端能够与气缸孔表面滑动接触以在其间形成压缩室。 可移动容量控制盘布置在一个侧板和转子之间的界面处,以控制引入的气体和/或返回的压缩气体的量以改变压缩机的容量。 容量控制盘通过插入在具有相对的工作室的卷轴筒中的卷轴致动器移动。 输出压力下的气体被引入第一工作室,输出压力下的油被引入第二工作室,而泄漏通道将油压减轻到中间压力。 弹簧还布置在第二工作室中以推动阀芯,并且阀在靠近第二工作室的油通道中布置,以响应于预定要求来调节阀芯的运动。
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公开(公告)号:US09285293B2
公开(公告)日:2016-03-15
申请号:US13811556
申请日:2011-07-22
申请人: Eisuke Seta , Tatsuya Nakai , Martin Schneebeli , Denes Szabo , Henning Loewe , Martin Heggli , Felix Hempel , Matthias Jaggi , Jorg Graupeter
发明人: Eisuke Seta , Tatsuya Nakai , Martin Schneebeli , Denes Szabo , Henning Loewe , Martin Heggli , Felix Hempel , Matthias Jaggi , Jorg Graupeter
CPC分类号: G01M17/027 , B60C99/006 , G01M17/02 , G01M17/06 , G06F17/5009 , G06F17/5018 , G06F17/5095 , G06F2217/16
摘要: Disclosed is a method for predicting tire performance in which a tire model, which comprises a tread pattern capable of imparting deformation by means of ground contact and/or transfer, and a snow model, in which a snow-covered road surface that comes into contact with the tire model is represented, are used to predict tire performance on the snow-covered road surface on the basis of physical quantities that occur in at least either of the tire model and the snow model. The snow model is modeled as an elasto-plastic body or an elastic body, the nonlinearity of the volume compression property of snow is represented by the relationship between the density or volume strain of the snow and the pressure of the snow, and the shear property of the snow is represented by the relationship between the yield stress of the snow and the pressure of the snow.
摘要翻译: 公开了一种用于预测轮胎性能的方法,其中包括能够通过地面接触和/或转移而赋予变形的胎面花纹的轮胎模型和与其接触的积雪路面的积雪模型 轮胎模型被表示,用于基于在轮胎模型和雪模型中的至少一个中发生的物理量来预测积雪路面上的轮胎性能。 雪模型被建模为弹性塑料体或弹性体,雪的体积压缩特性的非线性由雪的密度或体积应变与雪的压力之间的关系以及剪切特性 雪的屈服应力与雪的压力之间的关系来表示。
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公开(公告)号:US5801671A
公开(公告)日:1998-09-01
申请号:US630991
申请日:1996-04-12
CPC分类号: G09G3/3622 , G09G3/3692 , G09G2320/0223 , G09G3/2011 , G09G3/2014 , G09G3/2018 , G09G3/3681
摘要: A liquid crystal display panel 51 of N rows.times.M columns is driven by a segment driver 52 with two different voltages VS1, VS2, and by a common driver 53 with three voltages VC1, VC2, VC3. An output voltage waveform of the segment driver 52 is modulated for gradation display. The two different voltages VS1, VS2 are selected to be low voltages so as not to require high withstand voltage process in the segment driver 52, which makes it easier to integrated to a large scale in the case of realizing the segment driver 52 as a semiconductor integrated circuit.
摘要翻译: N行x列的液晶显示面板51由具有两个不同电压VS1,VS2的段驱动器52和具有三个电压VC1,VC2,VC3的公共驱动器53驱动。 段驱动器52的输出电压波形被调制用于灰度显示。 两个不同的电压VS1,VS2被选择为低电压,从而不需要段驱动器52中的高耐压工艺,这使得在实现作为半导体的段驱动器52的情况下更容易集成大规模 集成电路。
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公开(公告)号:US4838740A
公开(公告)日:1989-06-13
申请号:US221717
申请日:1988-07-20
CPC分类号: F04C28/14
摘要: A variable displacement vane compressor including a rotor rotatably supported between a pair of side plates secured to a cylinder, vanes movably supported in the rotor to define variable compression chambers in the cylinder, a reciprocally rotatable displacement control plate located between the rotor and one of the side plates for controlling the largest displacement of the compression chambers when closed, a spool chamber provided in one side plate and opposed to the displacement control plate, a spool which reciprocates in the spool chamber to define a first pressure chamber in which a refrigerant having a discharge pressure is introduced and a second pressure chamber in which an oil having the discharge pressure is introduced through a control valve unit in response to the suction pressure, the spool and the displacement control plate being interconnected by a connecting member and moving together, a seal ring between the displacement control plate and the one side plate, for isolating a high pressure area from a low pressure area, and feed passages for introducing the oil having the discharge pressure to the sealing ring. The one side plate has an elongated hole which permits movement of the connecting member extending therethrough, and the seal ring has a diameter smaller than that of an imaginary circle centered on the rotation axis of the rotor and circumscribing the elongated hole. The seal ring is eccentric to the rotation axis and includes the elongated hole in the seal ring.
摘要翻译: 一种可变排量叶片式压缩机,包括可旋转地支撑在固定到气缸的一对侧板之间的转子,可移动地支撑在转子中以限定气缸中的可变压缩室的叶片,位于转子和其中一个之间的可往复旋转的位移控制板 用于控制关闭时的压缩室的最大排量的侧板,设置在一个侧板中并与位移控制板相对的卷轴室;卷轴,其在卷轴室中往复运动以限定第一压力室,在该第一压力室中具有 引入排出压力,并且第二压力室,其中具有排出压力的油通过控制阀单元响应于吸入压力被引入,阀芯和位移控制板通过连接构件互连并一起移动,密封件 位移控制板和一侧板之间的环形,用于隔离 从低压区域施加高压区域,以及用于将具有排出压力的油引入密封环的供给通道。 单侧板具有长孔,其允许延伸穿过其中的连接构件的移动,并且密封环的直径小于以转子的旋转轴线为中心并围绕长孔的假想圆的直径。 密封环对旋转轴线偏心并且包括密封环中的细长孔。
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公开(公告)号:US20050239868A1
公开(公告)日:2005-10-27
申请号:US10521958
申请日:2003-07-22
申请人: Hiroyuki Shirai , Tatsuya Nakai , Masami Serizawa , Yasuo Shinoda , Toshio Inagi
发明人: Hiroyuki Shirai , Tatsuya Nakai , Masami Serizawa , Yasuo Shinoda , Toshio Inagi
IPC分类号: A61K9/06 , A61K31/405 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38 , A61K47/44 , A61P29/00
CPC分类号: A61K9/06 , A61K9/0014 , A61K31/405 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/38 , A61K47/44
摘要: An object of the present invention is to provide an indomethacin external preparation that has an excellent use feeling and excellent absorbability and causes no phase separation into an oil layer and an aqueous layer, thus exhibiting satisfactory stability of preparation with time. Provided is an indomethacin external preparation containing: 0.1 to 3 wt % of indomethacin; 25 to 50 wt % of alcohol; 0.01 to 5 wt % of gelling agent; 5 to 30 wt % of oil component; 20 to 50 wt % of water; and 0.01 to 10 wt % of one or more components selected from the group consisting of glyceryl monostearate, sorbitan monostearate, stearyl alcohol, and polyethylene glycol monostearate.
摘要翻译: 本发明的目的是提供具有优异的使用感和优异的吸收性的吲哚美辛外用制剂,并且不会使相分离成油层和水层,从而表现出令人满意的制备时间稳定性。 本发明提供消炎痛外用制剂,含有0.1〜3重量%的吲哚美辛; 25〜50重量%的醇; 0.01〜5重量%的胶凝剂; 5〜30重量%的油成分; 20〜50重量%的水; 和0.01〜10重量%的选自单硬脂酸甘油酯,脱水山梨糖醇单硬脂酸酯,硬脂醇和聚乙二醇单硬脂酸酯的一种或多种成分。
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公开(公告)号:US5483867A
公开(公告)日:1996-01-16
申请号:US313357
申请日:1994-09-27
申请人: Hayato Ikeda , Tatsuya Nakai , Naoya Yokomachi , Masanobu Yokoi
发明人: Hayato Ikeda , Tatsuya Nakai , Naoya Yokomachi , Masanobu Yokoi
CPC分类号: F04B27/0886 , F04B27/1054 , Y10T74/18336
摘要: A swash plate type compressor incorporating therein a swash plate having an annular rail raised from each flat face thereof for providing a sliding-contact surface being in contact with sliding-contact surface portions of respective shoes which constitute a rotation-to-reciprocation conversion unit arranged between the swash plate and double-headed pistons reciprocating axial cylinder bores of the compressor. The sliding-contact surfaces of respective shoes bulge outward and have a radius of curvature "R" in the range of 800 through 1600 millimeters which is smaller than that of the conventional shoes of a swash plate type compressor, so that relatively large wedge shaped gaps are formed between the respective shoes and the swash plate to thereby stably and constantly hold lubricating oil.
摘要翻译: 一种旋转斜盘式压缩机,其内装有斜盘,该斜盘具有从其每个平面向上突出的环形轨道,用于提供滑动接触表面,该滑动接触表面与各个鞋的滑动接触表面部分接触,所述滑动接触表面部分构成旋转 - 往复转换单元, 在斜盘和双头活塞之间往复运动的压缩机的轴向气缸孔。 各鞋的滑动接触表面向外凸出,其曲率半径“R”在800至1600毫米的范围内,该曲率半径小于斜盘式压缩机的传统鞋的曲率半径,使得相对较大的楔形间隙 形成在各个鞋和斜盘之间,从而稳定且持续地保持润滑油。
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公开(公告)号:US20130124172A1
公开(公告)日:2013-05-16
申请号:US13811556
申请日:2011-07-22
申请人: Eisuke Seta , Tatsuya Nakai , Martin Schneebeli , Denes Szabo , Henning Loewe , Martin Heggli , Felix Hempel , Matthias Jaggi , Jorg Graupeter
发明人: Eisuke Seta , Tatsuya Nakai , Martin Schneebeli , Denes Szabo , Henning Loewe , Martin Heggli , Felix Hempel , Matthias Jaggi , Jorg Graupeter
CPC分类号: G01M17/027 , B60C99/006 , G01M17/02 , G01M17/06 , G06F17/5009 , G06F17/5018 , G06F17/5095 , G06F2217/16
摘要: Disclosed is a method for predicting tire performance in which a tire model, which comprises a tread pattern capable of imparting deformation by means of ground contact and/or transfer, and a snow model, in which a snow-covered road surface that comes into contact with the tire model is represented, are used to predict tire performance on the snow-covered road surface on the basis of physical quantities that occur in at least either of the tire model and the snow model. The snow model is modeled as an elasto-plastic body or an elastic body, the nonlinearity of the volume compression property of snow is represented by the relationship between the density or volume strain of the snow and the pressure of the snow, and the shear property of the snow is represented by the relationship between the yield stress of the snow and the pressure of the snow.
摘要翻译: 公开了一种用于预测轮胎性能的方法,其中包括能够通过地面接触和/或转移而赋予变形的胎面花纹的轮胎模型和与其接触的积雪路面的积雪模型 轮胎模型被表示,用于基于在轮胎模型和雪模型中的至少一个中发生的物理量来预测积雪路面上的轮胎性能。 雪模型被建模为弹性塑料体或弹性体,雪的体积压缩特性的非线性由雪的密度或体积应变与雪的压力之间的关系以及剪切特性 雪的屈服应力与雪的压力之间的关系来表示。
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公开(公告)号:US4844703A
公开(公告)日:1989-07-04
申请号:US225481
申请日:1988-07-28
IPC分类号: F04B49/00 , F04C18/344 , F04C28/14
CPC分类号: F04C28/14
摘要: A variable displacement vane compressor for an air conditioning system having at least one crescent chamber (R1, R2) defined by vanes (8), a rotor (6), and a bore of a cylindrical body (3). The cooling capacity is adjusted by rotational displacement of an annular plate member (21) for controlling the amount of refrigerant introduced into the crescent chamber (R1, R2). The annular plate member (21) is rotated by a spool (25) driven by a dynamic pressure balance between a first compartment (S1) to which a refrigerant gas under a discharging pressure is introduced, and of a second compartment (S2) to which an oil under a discharging pressure is introduced. The spool (25) is connected to the annular plate member (21) through a pin (26) penetrating an arcuate slot 27 formed in a front end wall plate member (4). A sealing means (35a, 36) for preventing the leakage of the refrigerant gas from the high pressure region including the first compartment (S 1) to the low pressure region is provided between the annular plate member (21) and the front end wall member (4). A pressurized oil is supplied to the sealing means (35a, 36) through an intermediate passage (37) to enhance the sealing effect of the sealing means (35a, 36). The intermediate passage (37) is separated from the arcuate slot (27) to prevent the high pressure oil from leaking into the first compartment (S1).
摘要翻译: 一种用于空调系统的可变排量叶片式压缩机,其具有由叶片(8),转子(6)和圆筒体(3)的孔限定的至少一个新月形腔(R1,R2)。 通过用于控制引入新月腔(R1,R2)的制冷剂量的环形板构件(21)的旋转位移来调整冷却能力。 环形板构件(21)由在引入排气压力的制冷剂气体的第一室(S1)和第二室(S2)之间的动压平衡驱动的阀芯(25)旋转,第二隔室 引入排出压力下的油。 卷轴(25)通过穿过形成在前端壁板构件(4)中的弓形狭槽27的销(26)连接到环形板构件(21)。 用于防止制冷剂气体从包括第一隔室(S1)到低压区域的高压区域泄漏的密封装置(35a,36)设置在环形板构件(21)和前端壁构件 (4)。 通过中间通路(37)向密封装置(35a,36)供给加压油,以增强密封装置(35a,36)的密封效果。 中间通道(37)与弧形槽(27)分离,以防止高压油泄漏到第一隔室(S1)中。
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