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公开(公告)号：US07794994B2
公开(公告)日：2010-09-14
申请号：US10494923
申请日：2002-11-08
申请人： Paul E. Cranley , Jeffrey R. Allen , Kristine L. Danowski , James A. McIntyre , Theodore E. Miller, Jr. , Bettina M. Rosner , Alan D. Strickland , Venkiteswaran Subramanian , Larry Sun
发明人： Paul E. Cranley , Jeffrey R. Allen , Kristine L. Danowski , James A. McIntyre , Theodore E. Miller, Jr. , Bettina M. Rosner , Alan D. Strickland , Venkiteswaran Subramanian , Larry Sun
CPC分类号： C12N9/0006 , C12P7/04 , C12P7/28 , C12Q1/005
摘要： Described are enzyme systems specific for acetone and methods of using these enzyme systems to detect acetone in biological or environmental samples. Biosensors containing these enzyme systems are disclosed, in which detection of acetone may be achieved by linking electrochemical, photometric, or other detection means to one or more acetone-specific enzyme reactions or pathways. Methods of using such acetone-specific biosensors include subject management of weight loss, disease detection, and bioavailability monitoring of therapeutics.
摘要翻译： 描述了丙酮特有的酶系统和使用这些酶系统检测生物或环境样品中的丙酮的方法。 公开了含有这些酶系统的生物传感器，其中可以通过将电化学，光度或其它检测手段与一种或多种丙酮特异性酶反应或途径连接来实现丙酮的检测。 使用这种丙酮特异性生物传感器的方法包括体重减轻，疾病检测和治疗剂的生物利用度监测的受试者管理。
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2.发明授权Method and apparatus for determining physical properties of a gas for use in rheometry 失效用于测定用于流变学的气体的物理性质的方法和装置
公开(公告)号：US5734093A
公开(公告)日：1998-03-31
申请号：US768744
申请日：1996-12-17
CPC分类号： G01N7/00 , G01F17/00 , G01N11/04 , G01N2009/028 , G01N9/26
摘要： A method and apparatus for determining a physical property of a gas in a confined space. Gas of known volume, pressure and temperature is placed in communication with a confined space containing gas at known pressure to determine the volume of gas in the confined space using computations based on the gas laws. Alternatively, gas of known pressure, volume, and temperature may be placed in communication with a confined space containing gas at known volume to determine the pressure of gas in the confined space prior to communication with the gas of known properties. Gas volume determinations are useful, for example, to perform rheological characterizations of liquid samples.
摘要翻译： 一种用于确定密闭空间中的气体的物理性质的方法和装置。 将已知体积，压力和温度的气体与含有已知压力的气体的密闭空间连通，以使用基于气体定律的计算来确定密闭空间中的气体体积。 或者，可以将已知压力，体积和温度的气体放置成与具有已知体积的气体的密闭空间连通，以在与已知性质的气体连通之前确定密闭空间内的气体压力。 气体体积测定可用于例如进行液体样品的流变学表征。
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公开(公告)号：US4628743A
公开(公告)日：1986-12-16
申请号：US738125
申请日：1985-06-14
CPC分类号： G01F11/00 , G01F1/7044 , G01F11/28 , G01F13/00
摘要： Apparatus for accurately metering liquid flow based on the injection of a brief heat pulse into the flowing stream, e.g., via a miniature thermistor, and detection of an electronic time derivative of temperature downstream with, e.g., a second microprobe thermistor. This detection triggers a subsequent heat pulse and the cycle repeats, with pulse total corresponding to elapsed liquid throughput, and pulse frequency to flow rate.
摘要翻译： 基于将短暂的热脉冲注入到流动流中，例如通过微型热敏电阻，以及利用例如第二微孔热敏电阻检测下游温度的电子时间导数的装置。 该检测触发随后的加热脉冲，循环重复，脉冲总数对应于经过的液体通过量，脉冲频率与流速。
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4.发明授权Analytical method for determining acid/salt and base/salt species concentration in solution 失效测定溶液中酸/盐和碱/盐物质浓度的分析方法
公开(公告)号：US4290775A
公开(公告)日：1981-09-22
申请号：US115837
申请日：1980-01-28
IPC分类号： G01N27/02 , G01N30/62 , G01N30/64 , G01N30/78 , G01N30/86 , G01N30/96 , G01N33/18 , G01N31/04 , G01N27/08
CPC分类号： G01N30/96 , G01N2030/625 , G01N2030/626 , G01N2030/645 , G01N30/78 , G01N30/8641 , Y10T436/153333 , Y10T436/25125
摘要： Analytical method based on converting an acid or base species to water or absorbing the acid species whereby the species of interest is no longer responsive to a detector. Interfering salt(s) is simultaneously converted to a detectable acid or hydroxide derivative(s) in whole or in part. The species of interest is determined indirectly by subtracting the response of the salt derivative (which is proportional to the original salt) from a pre-derivatization response which is proportional to the salt plus base or salt plus acid.
摘要翻译： 基于将酸或碱物质转化为水或吸收酸物质的分析方法，由此感兴趣的物种不再响应于检测器。 干扰盐同时转化为全部或部分可检测的酸或氢氧根衍生物。 通过从与盐加碱或盐加酸成比例的预衍生反应减去盐衍生物（与原盐成正比）的响应间接测定感兴趣的物种。
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5.发明授权Method for sensing individual ion concentrations within mixtures using sample front ion exchange elution and indirect photometric detection 失效使用样品前离子交换洗脱和间接光度检测来检测混合物内的各种离子浓度的方法
公开(公告)号：US5192691A
公开(公告)日：1993-03-09
申请号：US845867
申请日：1992-03-03
CPC分类号： G01N30/96 , G01N2030/326 , G01N30/02 , G01N30/60 , G01N30/6082 , G01N30/74 , Y10T436/255
摘要： A method of determining individual ion concentrations in mixtures using ion exchange separation combined with indirect photometric detection and frontal analysis.
摘要翻译： 使用离子交换分离结合间接光度检测和正面分析来确定混合物中的各离子浓度的方法。
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公开(公告)号：US5141131A
公开(公告)日：1992-08-25
申请号：US636031
申请日：1990-12-28
CPC分类号： C12N15/87 , C12M35/00 , C12N15/8207
摘要： An apparatus and method are taught for the acceleration of a propellable matter at selected target matter.
摘要翻译： 教导了在所选择的目标物质下加速可推动物质的装置和方法。
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公开(公告)号：US4813280A
公开(公告)日：1989-03-21
申请号：US33448
申请日：1987-04-01
CPC分类号： G01F1/6847 , G01F1/7084
摘要： A disposable flow cell for use in a thermal pulse flow meter of the type that incorporates a pulse heated thermal probe and a detecting thermal probe. The disposable cell has two side ports covered with a stretchable film barrier. The thermal probes extend into the flow cell through the ports stretching the barrier ahead of them so that the probes can transmit and then detect thermal pulses to a fluid flowing through the flow cell while at the same time maintaining isolation between the probes and the fluid. The invention is also a thermal pulse flow meter incorporating the above cell.
摘要翻译： 一种用于热脉冲流量计的一次性流通池，其包含脉冲加热的热探针和检测热探针。 一次性电池具有覆盖有可拉伸薄膜屏障的两个侧面端口。 热探针通过延伸其前面的屏障的端口延伸到流动池中，使得探针可以传递并且然后将热脉冲检测到流过流动池的流体，同时保持探针和流体之间的隔离。 本发明也是结合上述电池的热脉冲流量计。
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公开(公告)号：US4567753A
公开(公告)日：1986-02-04
申请号：US682032
申请日：1984-12-12
摘要： An improved technique and apparatus for the independent measurement of anions and cations in solution, wherein the sample ions are chromatographically displaced in a plurality of ion exchange columns by an eluting ion which is or is made light-absorbing and wherein the sample ions are detectable from decrements in absorbance of the eluting ions as revealed by photometric monitoring; and the sample ions, cations and anions, are further detected independently by means for monitoring eluting anion and cation absorbance differences calibrated according to characteristic absorbance ratios of the selected eluting ion species at a plurality of wavelengths.
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公开(公告)号：US4527421A
公开(公告)日：1985-07-09
申请号：US570331
申请日：1984-01-13
IPC分类号： G01N13/02
CPC分类号： G01N13/02 , G01N2013/0266
摘要： An improved apparatus and method are disclosed for measuring the dynamic surface tension at a gas-liquid interface by the maximum bubble pressure method. The gas is bubbled out an orifice tube dipped in the liquid; the maximum pressure in each bubble is a function of the surface tension. In the invention, the rate of gas flow is raised continually to increase the rate of bubbling at least several fold over a few minutes. The varying pressure of the bubbling gas is measured continuously by an instantaneous transducer. Electronic circuits respond to the transducer and provide signals indicative of the maximum bubble pressure and of the rates of bubbling. A recorder responds to the signals and displays a spectrum of the maximum bubble pressure in units indicative of surface tension as a function of the bubbling rate. Measurements may be taken over more than a thousand bubbles in each spectrum. The rise in gas pressure is achieved by passing gas from a source under pressure in series through two flow-restricting capillaries, with an accumulator zone between.
摘要翻译： 公开了一种改进的装置和方法，用于通过最大气泡压力法测量气 - 液界面处的动态表面张力。 将气体从浸入液体中的孔管鼓泡出来; 每个气泡中的最大压力是表面张力的函数。 在本发明中，气流的速率连续地升高，在几分钟内至少增加几倍的起泡速率。 鼓泡气体的变化压力由瞬时换能器连续测量。 电子电路响应换能器并提供指示最大气泡压力和起泡速率的信号。 记录器对信号进行响应，并以指示表面张力的单位显示最大气泡压力的光谱作为起泡速率的函数。 每个光谱可以测量超过一千个泡泡。 气体压力的升高是通过使来自压力的源的气体串联通过两个流动限制的毛细管而实现的，其间具有蓄积区。
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公开(公告)号：US4917575A
公开(公告)日：1990-04-17
申请号：US261056
申请日：1988-10-27
CPC分类号： F04B19/24 , G01N30/32 , G01N2030/326
摘要： A liquid chromatographic method and apparatus is disclosed which employs an improved pump not requiring driven pistons or sliding seals. The pump comprises at least one length of tubing forming a chamber disposed between first and second check valves, controllable heating means to periodically heat liquid in said chamber effective to pump relatively low volumes of liquid from the chamber at relatively high pressures, means for measuring the pressure developed by the pump, and control means to increase and decrease the amount of heat imparted to the liquid to maintain the pump operation at a controlled pressure setpoint.
摘要翻译： 公开了一种使用不需要驱动活塞或滑动密封件的改进的泵的液相色谱方法和装置。 所述泵包括形成设置在第一和第二止回阀之间的腔室的至少一段管道，可控加热装置以周期性地加热所述腔室中的液体，以有效地在相对高的压力下泵送来自腔室的相对较小体积的液体， 由泵开发的压力以及控制装置来增加和减少施加到液体的热量，以将泵的操作保持在受控的压力设定点。
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