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1.发明申请METHOD AND KIT FOR THE CLASSIFICATION AND PROGNOSIS OF TISSUE OR ORGAN FIBROSIS IN A REPARATIVE OR REACTIVE PROCESS 审中-公开组织或组织纤维化在复原或反应过程中的分类和预防的方法和工具公开(公告)号：US20150087527A1
公开(公告)日：2015-03-26
申请号：US14389431
申请日：2013-03-29
Applicant: VIVATECH , Centre National de la Recherche Scientifique- CNRS , Universite Paris Diderot- Paris 7 , Ecole Normale Superieure
Inventor： Claire Dugast Darzacq , Xavier Darzacq , Maite Noizet , Emilie Lagoutte , Hugues Roest Crollius , Marlene Gratigny , Marielle Bouschbacher
CPC classification number: C12Q1/6883 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178 , G01N33/6893 , G01N2800/20 , G01N2800/52
Abstract: The invention relates to methods of diagnosis or prognosis of a tissue or organ fibrosis (e.g., skin fibrosis, hypertrophic scar or a keloid) in a reparative or reactive process comprising the step of determining the levels of expression of genes encoding different molecular markers in a sample of a tissue or organ from a mammalian, wherein different genes markers are studied.
Abstract translation: 本发明涉及在修复或反应过程中组织或器官纤维化的诊断或预后的方法（例如，皮肤纤维化，肥大性瘢痕或瘢痕疙瘩），其包括确定编码不同分子标记物的基因的表达水平的步骤 来自哺乳动物的组织或器官的样品，其中研究不同的基因标记。
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2.发明授权公开(公告)号：US09642790B2
公开(公告)日：2017-05-09
申请号：US14405897
申请日：2013-06-07
Applicant: Vivatech , Centre National de la Recherche Scientifique—CNRS , Ecole Superieure de Physique et Chimie Industrielles de la Ville de Paris
Inventor： Ludwik Leibler , Francois Tournilhac , Aggeliki Triftaridou , Eva-Maria Leuschner , Stephane Auguste , Jean-Marc Pernot
IPC: C08L33/12 , A61K9/10 , A61K8/37 , A61K8/81 , A61K47/32 , C08J5/18 , C08F265/06 , A61K9/70 , A61K8/44 , A61Q17/04 , A61K8/02 , C08L33/08 , C08L101/12
CPC classification number: A61K8/8147 , A61K8/0279 , A61K8/37 , A61K8/44 , A61K8/8152 , A61K9/10 , A61K9/7015 , A61K47/32 , A61K2800/413 , A61K2800/56 , A61Q17/04 , C08F265/06 , C08J5/18 , C08J2300/12 , C08J2400/12 , C08L33/08 , C08L33/12 , C08L101/12 , C08L2207/02 , C08F220/18
Abstract: The present invention concerns an aqueous dispersion of multiphase polymer particles in which the polymer particles comprise at least two separate phases, the internal phase being formed by polymerization in the presence of a crosslinking agent, said dispersion further comprising a surfactant chosen from amino acid derivatives. The invention also concerns a film-forming composition comprising said aqueous dispersion of polymer particles. The invention also relates to a film obtained after application of said film-forming composition. This film dries very quickly, is water resistant, and has good adhesion, elasticity and breaking strength properties. The invention also concerns the use of said film for protecting surfaces of the skin or mucous membranes, wounds, injuries and/or skin disorders.
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公开(公告)号：US20160374862A1
公开(公告)日：2016-12-29
申请号：US15104277
申请日：2014-12-19
Applicant: VIVATECH , LABORATOIRES URGO , HCP HEALTHCARE ASIA PTE.LTD
Inventor： Jean-Marc Pernot
IPC: A61F13/00
CPC classification number: A61F13/00068 , A61F13/00021 , A61F13/00029 , A61F13/00042 , A61F2013/00119 , A61L15/60 , C08L33/26 , C08L33/02
Abstract: The subject of the present invention is a composite wound packing material comprising a casing enclosing a material, or an assembly of materials, forming fluid flow channels, said casing being composed of a nonwoven material formed from a mixture of bicomponent superabsorbent fibers and non-absorbent thermal bonding fibers, said bicomponent superabsorbent fibers being of core/shell type, said core being made of polyacrylonitrile and the shell being made of polyacrylate.
Abstract translation: 本发明的主题是复合伤口包装材料，其包括封闭材料的壳体或形成流体流动通道的材料组件，所述壳体由由双组分超吸收性纤维和非吸收性纤维的混合物形成的非织造材料 热粘合纤维，所述双组分超吸收纤维为核/壳型，所述芯由聚丙烯腈制成，壳由聚丙烯酸酯制成。
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Patent Agency Ranking
公开(公告)号：US10398815B2
公开(公告)日：2019-09-03
申请号：US15104324
申请日：2014-12-19
Applicant: LABORATORIES URGO , VIVATECH , HCP HEALTHCARE ASIA PTE. LTD
Inventor： Jean-Marc Pernot
Abstract: The subject of the present invention is a composite wound packing material comprising a casing enclosing a material, or an assembly of materials, forming fluid flow channels, said casing being composed of a self-supporting interface material formed from a thin layer of a composition comprising a hydrophobic matrix and comprising through-holes, said hydrophobic matrix comprising, per 100 parts by weight of a styrene/saturated olefin/styrene triblock copolymer having a viscosity of between 0.2 and 2 Pa·s, as measured in a 10% (weight/weight) solution in toluene, from 400 to 1220 parts by weight of a plasticizer, preferably a plasticizing oil, and from 0 to 720 parts by weight of petroleum jelly, it being specified, moreover, that the total amount of plasticizer and petroleum jelly is greater than or equal to 750 parts by weight and the amount of petroleum jelly is between 400 and 720 parts by weight when the amount of plasticizer is between 1000 and 1220 parts by weight.
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5.发明申请AQUEOUS DISPERSION OF POLYMER PARTICLES, FILM-FORMING COMPOSITION CONTAINING SAME AND USES THEREOF 审中-公开聚合物颗粒的水分散，含有其的成膜组合物及其用途公开(公告)号：US20150174042A1
公开(公告)日：2015-06-25
申请号：US14405897
申请日：2013-06-07
Applicant: Vivatech , Centre National de la Recherche Scientifique-CNRS , Ecole Superieure de Physique et Chimie Industrielles de la Ville de Paris
Inventor： Ludwik Leibler , Francois Tournilhac , Aggeliki Triftaridou , Eva-Maria Leuschner , Stephane Auguste , Jean-Marc Pernot
CPC classification number: A61K8/8147 , A61K8/0279 , A61K8/37 , A61K8/44 , A61K8/8152 , A61K9/10 , A61K9/7015 , A61K47/32 , A61K2800/413 , A61K2800/56 , A61Q17/04 , C08F265/06 , C08J5/18 , C08J2300/12 , C08J2400/12 , C08L33/08 , C08L33/12 , C08L101/12 , C08L2207/02 , C08F220/18
Abstract: The present invention concerns an aqueous dispersion of multiphase polymer particles in which the polymer particles comprise at least two separate phases, the internal phase being formed by polymerisation in the presence of a crosslinking agent, said dispersion further comprising a surfactant chosen from amino acid derivatives. The invention also concerns a film-forming composition comprising said aqueous dispersion of polymer particles. The invention also relates to a film obtained after application of said film-forming composition. This film dries very quickly, is water resistant, and has good adhesion, elasticity and breaking strength properties. The invention also concerns the use of said film for protecting surfaces of the skin or mucous membranes, wounds, injuries and/or skin disorders.
Abstract translation: 本发明涉及多相聚合物颗粒的水分散体，其中聚合物颗粒包含至少两个分开的相，内相通过在交联剂存在下聚合形成，所述分散体还包含选自氨基酸衍生物的表面活性剂。 本发明还涉及包含聚合物颗粒的所述水性分散体的成膜组合物。 本发明还涉及在施用所述成膜组合物之后获得的膜。 该膜干燥速度非常快，具有防水性，具有良好的附着力，弹性和断裂强度特性。 本发明还涉及所述膜用于保护皮肤或粘膜表面，伤口，损伤和/或皮肤病症的用途。
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公开(公告)号：US20150126447A1
公开(公告)日：2015-05-07
申请号：US14389420
申请日：2013-03-29
Applicant: VIVATECH , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS , UNIVERSITE PARIS DIDEROT - PARIS 7 , ECOLE NORMALE SUPERIEURE
Inventor： Claire Dugast Darzacq , Xavier Darzacq , Maite Noizet , Emilie Lagoutte , Hugues Roest Crollius , Marlene Gratigny , Marielle Bouschbacher
CPC classification number: C12Q1/6883 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178 , G01N33/6893 , G01N2800/20 , G01N2800/52
Abstract: The present invention relates to a method and kit for the classification and prognosis of wounds of mammalian, in particular in human. The method defines a molecular signature that enables one to characterize a pathological wound healing such as chronic or non-healing wound.
Abstract translation: 本发明涉及哺乳动物，特别是人的伤口分类和预后的方法和试剂盒。 该方法定义了能够描述病理性伤口愈合的分子特征，例如慢性或非愈合伤口。
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7.发明授权Skin wound treatment method, dressing and biochemical activation device for the use of such a method 有权皮肤伤口治疗方法，敷料和生化激活装置使用这种方法公开(公告)号：US08997752B2
公开(公告)日：2015-04-07
申请号：US13870089
申请日：2013-04-25
Applicant: Vivatech Company
Inventor： Alain Cornil
CPC classification number: A61B18/203 , A61B90/98 , A61B2018/00452 , A61B2090/061
Abstract: The present invention relates to a system for treatment of skin wounds, comprising an energy source for activation of a biochemical healing effect, and at least one dressing intended to be placed on the wound before the step of activation by said energy source, characterized in that said dressing comprises an identification means interacting in a contactless manner with a sensor that triggers the function of the energy source only when the distance between the sensor and said identification means is below a threshold value.
Abstract translation: 本发明涉及用于治疗皮肤伤口的系统，其包括用于激活生化愈合作用的能量源，以及用于在由所述能量源激活的步骤之前置于伤口上的至少一种敷料，其特征在于： 所述敷料包括识别装置，其仅在传感器和所述识别装置之间的距离低于阈值时才以无接触方式与仅触发能量源的功能的传感器相互作用。
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8.发明申请公开(公告)号：US20130317489A1
公开(公告)日：2013-11-28
申请号：US13870089
申请日：2013-04-25
Applicant: VIVATECH COMPANY
Inventor： Alain Cornil
IPC: A61B18/20
CPC classification number: A61B18/203 , A61B90/98 , A61B2018/00452 , A61B2090/061
Abstract: The present invention relates to a system for treatment of skin wounds, comprising an energy source for activation of a biochemical healing effect, and at least one dressing intended to be placed on the wound before the step of activation by said energy source, characterized in that said dressing comprises an identification means interacting in a contactless manner with a sensor that triggers the function of the energy source only when the distance between the sensor and said identification means is below a threshold value.
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