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    Method and apparatus for producing ammonia (NH3)
    1.
    发明授权
    Method and apparatus for producing ammonia (NH3) 有权
    生产氨（NH3）的方法和装置

    公开(公告)号：US06928807B2

    公开(公告)日：2005-08-16

    申请号：US10369348

    申请日：2003-02-14

    申请人： Eberhard Jacob ,  Sebastian Käfer ,  Werner Müller ,  Andreas Lacroix ,  Andreas Herr

    发明人： Eberhard Jacob ,  Sebastian Käfer ,  Werner Müller ,  Andreas Lacroix ,  Andreas Herr

    IPC分类号： B01D53/86 ,  B01D53/90 ,  B01D53/94 ,  C01C1/02 ,  C01C1/08 ,  F01N3/20 ,  F01N3/00

    CPC分类号： F01N3/2066 ,  B01D53/8631 ,  B01D53/90 ,  B01D53/9431 ,  C01C1/02 ,  C01C1/086 ,  F01N2240/25 ,  F01N2240/40 ,  F01N2610/02 ,  F01N2610/06 ,  F01N2610/10 ,  F17C11/00 ,  Y02A50/2325 ,  Y02E20/14 ,  Y02P20/129 ,  Y02P20/13 ,  Y02T10/24

    摘要： A method is provided for producing ammonia (NH3) and introducing the produced ammonia (NH3) into an exhaust gas stream as a reduction means for selectively catalytically reducing nitrogen oxides contained in the exhaust gas stream, which is an exhaust stream generated by the combustion process of a motor, a gas turbine, or a burner. The method comprises feeding dry urea from a supply container in a controlled amount to reactor and subjecting the dry urea in the reactor to a sufficiently rapid thermal treatment such that a gas mixture comprising the reaction products of ammonia (NH3) and isocyanic acid (HCNO) is created. Also, the method comprises immediately catalytically treating the thus produced gas mixture in the presence of water such that the isocyanic acid (HCNO) resulting from the rapid thermal treatment is converted, via quantitative hydrolysis treatment, into ammonia (NH3) and carbon dioxide (CO2).

    摘要翻译： 提供了一种用于生产氨（NH 3）并将生成的氨（NH 3））引入废气流中的方法，作为用于选择性催化还原氮氧化物的还原装置 在废气流中，其是通过电动机，燃气轮机或燃烧器的燃烧过程产生的排气流。 该方法包括将干燥的尿素从受控量的供应容器中加入到反应器中，并对反应器中的干燥尿素进行足够快速的热处理，使得包含氨的反应产物（NH 3）的气体混合物 >）和异氰酸（HCNO）。 此外，该方法包括在水的存在下立即催化处理由此产生的气体混合物，使得通过定量水解处理将快速热处理产生的异氰酸（HCNO）转化为氨（NH 3） SUB>）和二氧化碳（CO 2/2）。

    Clutch segment
    2.
    发明授权
    Clutch segment 有权
    离合器段

    公开(公告)号：US06889810B2

    公开(公告)日：2005-05-10

    申请号：US10440059

    申请日：2003-05-16

    申请人： Werner Müller

    发明人： Werner Müller

    IPC分类号： F16D7/08 ,  F16D7/06

    CPC分类号： F16D7/08

    摘要： A device for coupling and decoupling two shafts or other elements of a drive train for transmitting rotations or torques especially to be used as a clutch segment in the field of motorcycle drives is provided. The clutch segment includes two parts one of which comprise troughs or recesses being arranged on a circle and offset by essentially the same angle. The troughs are at least approximately tangentially abutting an inner circle. The troughs linearly extend from their deepest point, beginning with a radius of the inner circle, at an angle towards an edge thereof and turn over towards the edge of a radius. A force application point for applying a force for coupling or decoupling the elements is located at a distance from a rotation axis of the clutch segment.

    摘要翻译： 提供了一种用于耦合和去耦合传动系的两个轴或其它元件的装置，用于传递转动或扭矩，特别是用作摩托车驱动器领域中的离合器段。 离合器段包括两部分，其中之一包括设置在圆周上并以基本上相同的角度偏移的槽或凹槽。 槽至少大致切向地邻接内圆。 槽从其最深点线性延伸，从内圆的半径开始，朝向其边缘成一定角度并向半径的边缘转过。 用于施加用于联接或解耦元件的力的力施加点位于距离离合器段的旋转轴线一定距离处。

    1-aza-bicyclo[3.3.1]nonanes
    3.
    发明授权
    1-aza-bicyclo[3.3.1]nonanes 有权
    1-氮杂 - 双环[3.3.1]壬烷

    公开(公告)号：US08933090B2

    公开(公告)日：2015-01-13

    申请号：US12907506

    申请日：2010-10-19

    申请人： Dominik Feuerbach ,  Werner Müller ,  Bernard Lucien Roy ,  Thomas J. Troxler ,  Konstanze Hurth ,  Mathias Frederiksen

    发明人： Dominik Feuerbach ,  Werner Müller ,  Bernard Lucien Roy ,  Thomas J. Troxler ,  Konstanze Hurth ,  Mathias Frederiksen

    IPC分类号： A61K31/506 ,  C07D239/28 ,  C07D471/08 ,  A61P29/00 ,  A61P25/28 ,  A61P25/16 ,  A61P25/24

    CPC分类号： C07D471/08

    摘要： The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R1); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4); R represent a hydrogen, C1-C4alkyl, or CF3; R2 represents hydrogen, C1-C4alkyl, or CF3; R3 represents hydrogen, C1-C4alkyl, or CF3; R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl; in free base or acid addition salt form.

    摘要翻译： 本发明涉及式（I）的1-氮杂 - 双环烷基衍生物; 其中取代基如本说明书中所定义，其制备方法，它们作为药物的用途以及包含它们的药物组合物。 式（I）其中A表示O或N（R1）; Y表示一组式，或其中左键连接至A基团，右键连接至R基团; R代表取代或未取代的C 5 -C 10芳基，取代或未取代的杂-C 5 -C 10芳基，基团N（R 1）（R 4）或基团N（R 2）（CH 3 R 4）。 R代表氢，C1-C4烷基或CF3; R 2表示氢，C 1 -C 4烷基或CF 3; R3表示氢，C1-C4烷基或CF3; R4表示取代或未取代的C5-C10芳基或取代或未取代的C5-C10杂芳基; 在游离碱或酸加成盐形式。

    COVALENTLY LINKED INTERLEUKIN-10
    4.
    发明申请
    COVALENTLY LINKED INTERLEUKIN-10 审中-公开
    共同链接的INTERLEUKIN-10

    公开(公告)号：US20130316404A1

    公开(公告)日：2013-11-28

    申请号：US13989425

    申请日：2011-11-25

    申请人： Axel Roers ,  Sebastian Lanvermann ,  Werner Müller

    发明人： Axel Roers ,  Sebastian Lanvermann ,  Werner Müller

    IPC分类号： C07K14/54

    CPC分类号： C07K14/5428 ,  A61K38/00 ,  C07K2319/00

    摘要： The present invention relates to a polypeptide having interleukin-10 function, comprising two interleukin-10 monomer subunits covalently linked by a linker. The present invention further relates to a nucleic acid molecule encoding the polypeptide of the invention, a vector comprising said nucleic acid molecule, a non-human host transformed with the nucleic acid molecule or the vector of the invention as well as a method for the production of a recombinant polypeptide of the invention. The present invention further relates to a pharmaceutical composition as well as to the polypeptide, the nucleic acid molecule, the vector or the host or host cell of the invention for use in treating and/or preventing inflammatory diseases.

    摘要翻译： 本发明涉及具有白细胞介素-10功能的多肽，其包含由接头共价连接的两个白细胞介素-10单体亚基。 本发明还涉及编码本发明多肽的核酸分子，包含所述核酸分子的载体，用本发明的核酸分子或载体转化的非人宿主以及生产方法 的本发明的重组多肽。 本发明还涉及药物组合物以及用于治疗和/或预防炎性疾病的本发明的多肽，核酸分子，载体或宿主或宿主细胞。

    1-AZA-BICYCLO[3.3.1]NONANES
    7.
    发明申请
    1-AZA-BICYCLO[3.3.1]NONANES 审中-公开
    1-AZA-BICYCLO [3.3.1] NONANES

    公开(公告)号：US20110034475A1

    公开(公告)日：2011-02-10

    申请号：US12907506

    申请日：2010-10-19

    申请人： Dominik FEUERBACH ,  Werner Müller ,  Bernard Lucien Roy ,  Thomas J. Troxler ,  Konstanze Hurth ,  Mathias Frederiksen

    发明人： Dominik FEUERBACH ,  Werner Müller ,  Bernard Lucien Roy ,  Thomas J. Troxler ,  Konstanze Hurth ,  Mathias Frederiksen

    IPC分类号： A61K31/501 ,  C07D487/08 ,  A61K31/439 ,  A61K31/506 ,  A61P25/18 ,  A61P25/28

    CPC分类号： C07D471/08

    摘要： The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R1); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C5-C10aryl, substituted or unsubstituted hetero-C5-C10aryl, a group N(R1)(R4), or a group N(R2)(CHP3R4); R represent a hydrogen, C1-C4alkyl, or CF3; R2 represents hydrogen, C1-C4alkyl, or CF3; R3 represents hydrogen, C1-C4alkyl, or CF3; R4 represents a substituted or unsubstituted C5-C10 aryl or a substituted or unsubstituted C5-C10heteroaryl; in free base or acid addition salt form.

    摘要翻译： 本发明涉及式（I）的1-氮杂 - 双环烷基衍生物; 其中取代基如本说明书中所定义，其制备方法，它们作为药物的用途以及包含它们的药物组合物。 式（I）其中A表示O或N（R1）; Y表示一组式，或其中左键连接至A基团，右键连接至R基团; R代表取代或未取代的C 5 -C 10芳基，取代或未取代的杂-C 5 -C 10芳基，基团N（R 1）（R 4）或基团N（R 2）（CH 3 R 4）。 R代表氢，C1-C4烷基或CF3; R 2表示氢，C 1 -C 4烷基或CF 3; R3表示氢，C1-C4烷基或CF3; R4表示取代或未取代的C5-C10芳基或取代或未取代的C5-C10杂芳基; 在游离碱或酸加成盐形式。

    Method for producing eyeglasses
    10.
    发明授权
    Method for producing eyeglasses 有权
    眼镜生产方法

    公开(公告)号：US06655802B2

    公开(公告)日：2003-12-02

    申请号：US10019877

    申请日：2002-12-12

    申请人： Martin Zimmermann ,  Peter Baumbach ,  Walter Haimerl ,  Herbert Pfeiffer ,  Gregor Esser ,  Jochen Brosig ,  Werner Müller ,  Martin Wechs ,  Helmut Altheimer ,  Rainer Dorsch ,  Winfried Nikolaus

    发明人： Martin Zimmermann ,  Peter Baumbach ,  Walter Haimerl ,  Herbert Pfeiffer ,  Gregor Esser ,  Jochen Brosig ,  Werner Müller ,  Martin Wechs ,  Helmut Altheimer ,  Rainer Dorsch ,  Winfried Nikolaus

    IPC分类号： G02C706

    CPC分类号： G02C7/061 ,  G02C7/024 ,  G02C7/025 ,  G02C7/027

    摘要： What is described here is a method of manufacturing spectacles comprising individual progressive ophthalmic lenses, including the following steps: selection of a spectacle frame, detection of the shape of the lens rings with a precision better than ±0.5 mm in the x- and y-directions (data set 1), detecting the intersection points of the lines of sight through the plane of the lens rings for at least two design distances of the progressive ophthalmic lenses with a precision better than ±1 mm (data set 2) selection and positioning relative to the lens rings of a spherical or non-spherical surface in view of the prescription data, using the data sets 1 and 2 (data set 3), computing and positioning the progressive surface relative to the selected surface, with minimization of the critical thickness of the ophthalmic lens, using the data sets 1 to 3 (data set 4), manufacturing the progressive surfaces as well as edges of the ophthalmic lenses from a non-edged semi-finished product finished on one side, using the data sets 1 to 4.

    摘要翻译： 这里描述的是制造包括单独的渐进式眼科镜片的眼镜的方法，包括以下步骤：选择眼镜框，在x轴和y轴中以+/- 0.5mm的精度检测透镜环的形状， 方向（数据组1），以超过±1mm的精度（数据组2）选择和定位检测渐进式眼镜片至少两个设计距离的透镜环平面的视线的交点 考虑到处方数据，相对于球形或非球形表面的透镜环，使用数据集1和2（数据集3），相对于所选择的表面计算和定位渐进表面，以最小化临界值 使用数据组1〜3（数据组4），使用数字组1〜3（数据组4），从在o上完成的非边缘半成品制造眼科镜片的边缘以及眼镜片的边缘 使用数据集1到4。