公开(公告)号：US20170086737A1

公开(公告)日：2017-03-30

申请号：US15373335

申请日：2016-12-08

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mary Beth Kossuth ,  Richard J. Rapoza ,  Joel Harrington

IPC: A61B5/00 ,  A61L29/14 ,  A61L29/18 ,  A61L31/14 ,  A61F2/91 ,  A61L31/18

CPC classification number: A61B5/4851 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  A61F2/91 ,  A61L29/146 ,  A61L29/18 ,  A61L31/146 ,  A61L31/18 ,  G01B9/02091 ,  H01L21/0337 ,  H01L21/31144

Abstract: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.

公开(公告)号：US09548215B2

公开(公告)日：2017-01-17

申请号：US14250023

申请日：2014-04-10

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Mary Beth Kossuth ,  Richard J. Rapoza ,  Joel Harrington

IPC: A61F2/89 ,  B23K26/00 ,  A61F2/95 ,  B23K26/40 ,  A61B19/00 ,  A61B5/00 ,  H01L21/311 ,  H01L21/033 ,  A61L31/14 ,  A61L31/18 ,  A61F2/91 ,  G01B9/02

CPC classification number: A61B5/4851 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  A61F2/91 ,  A61L29/146 ,  A61L29/18 ,  A61L31/146 ,  A61L31/18 ,  G01B9/02091 ,  H01L21/0337 ,  H01L21/31144

Abstract: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.

Abstract translation: 内置假体，用于成像内假体的方法，制造内假体的方法涉及已经被修改为具有嵌入衬底内的空隙的聚合物基底。 空隙的大小适于散射来自衬底内的光辐射，使得可以获得光学相干断层摄影（OCT）图像，其中衬底的内部区域可以容易地与空间和围绕内置假体的其他结构区分开。 空隙允许聚合物基底的OCT可视化，其可能难以通过诸如荧光透视的其它方法可视化。

公开(公告)号：US20170049592A1

公开(公告)日：2017-02-23

申请号：US14831693

申请日：2015-08-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Chad J. Abunassar ,  Diem U. Ta ,  Richard J. Rapoza

IPC: A61F2/89 ,  B29C69/00 ,  B29C49/42 ,  A61F2/82 ,  A61F2/915

CPC classification number: B29C69/001 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91575 ,  A61F2230/0006 ,  A61F2250/0036 ,  A61F2250/0098 ,  B29C49/4268 ,  B29C2793/0063 ,  B29L2031/7546

Abstract: A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.

Abstract translation: 支架支架的形状可改善血液相容性。 支架由具有可变壁厚的管制成。 公开了用于改变管的厚度的方法，以便实现减少的血流动力学特征，但是当支架被装载时，在存在应力集中的区域中没有显着影响强度性质。

公开(公告)号：US20150073535A1

公开(公告)日：2015-03-12

申请号：US14120555

申请日：2014-06-02

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Paul Consigny ,  Richard J. Rapoza ,  Syed Faiyaz Ahmed Hossainy ,  Chad J. Abunassar ,  Alexander J. Sheehy ,  Laura E. Perkins ,  Santosh V. Prabhu ,  Wai-Fung Cheong ,  Pooja A. Sadarangani ,  Stephen D. Pacetti

IPC: A61L31/14 ,  A61L31/16 ,  A61F2/06

CPC classification number: A61L31/148 ,  A61F2/915 ,  A61F2002/91566 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/402 ,  A61L2300/416

Abstract: Methods of treating coronary artery disease (CAD) with bioresorbable stents resulting in reduced angina or non-ischemic chest pain are described. Methods of treatment and devices for treatment of angina and post-procedural chest pain that include anti-angina agents incorporated into the device are disclosed.

Abstract translation: 描述了具有导致心绞痛或非缺血性胸痛减轻的生物可再吸收支架的冠状动脉疾病（CAD）的方法。 公开了治疗方法和治疗心绞痛和手术后胸痛的装置，其包括并入装置中的抗心绞痛药物。

公开(公告)号：US09908297B2

公开(公告)日：2018-03-06

申请号：US14831693

申请日：2015-08-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Chad J. Abunassar ,  Diem U. Ta ,  Richard J. Rapoza

IPC: A61F2/89 ,  B29C69/00 ,  A61F2/915 ,  B29C49/42 ,  B29L31/00 ,  A61F2/91

CPC classification number: B29C69/001 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91575 ,  A61F2230/0006 ,  A61F2250/0036 ,  A61F2250/0098 ,  B29C49/4268 ,  B29C2793/0063 ,  B29L2031/7546

Abstract: A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.

公开(公告)号：US20150290002A1

公开(公告)日：2015-10-15

申请号：US14250023

申请日：2014-04-10

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Mary Beth Kossuth ,  Richard J. Rapoza ,  Joel Harrington

IPC: A61F2/89 ,  B23K26/00 ,  A61F2/95 ,  B23K26/40 ,  A61B19/00 ,  A61B5/00

CPC classification number: A61B5/4851 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  A61F2/91 ,  A61L29/146 ,  A61L29/18 ,  A61L31/146 ,  A61L31/18 ,  G01B9/02091 ,  H01L21/0337 ,  H01L21/31144

Abstract: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.

Abstract translation: 内置假体，用于成像内假体的方法，制造内假体的方法涉及已经被修改为具有嵌入衬底内的空隙的聚合物基底。 空隙的大小适于散射来自衬底内的光辐射，使得可以获得光学相干断层摄影（OCT）图像，其中衬底的内部区域可以容易地与空间和围绕内置假体的其他结构区分开。 空隙允许聚合物基底的OCT可视化，其可能难以通过诸如荧光透视的其它方法可视化。