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公开(公告)号:US09861508B2
公开(公告)日:2018-01-09
申请号:US15398425
申请日:2017-01-04
IPC分类号: B23K26/40 , A61F2/915 , B23K26/402 , B29C35/08 , B23K103/00 , B29K67/00 , B29K105/00 , B29L31/00
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2002/91583 , A61F2240/001 , B23K26/38 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C35/0805 , B29C2035/0838 , B29K2067/00 , B29K2105/005 , B29K2105/258 , B29K2995/006 , B29L2031/7532
摘要: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.
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公开(公告)号:US09744625B2
公开(公告)日:2017-08-29
申请号:US15200876
申请日:2016-07-01
发明人: Joel Harrington , Ryan Vaughan , Kevin Jow , William Pippey , Yung-Ming Chen
IPC分类号: B29C35/08 , B23K26/402 , A61F2/91 , A61F2/90 , B23K26/0622 , A61F2/915 , B23K103/00
CPC分类号: B23K26/402 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2240/001 , B23K26/0624 , B23K2103/42 , B23K2103/50
摘要: The present invention involves laser machining polymer substrates to form a stent with laser parameters that minimize damage to the substrate in a surface region adjacent to the machined edge surface. The wavelength and pulse width are selected for this unique application and they can be controlled to minimize the surface modifications (such as voids, cracks which are induced by the laser-material interaction) which contribute to the variation in mechanical properties with distance from the edge surface, bulk mechanical properties, or a combination thereof.
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公开(公告)号:US20170086737A1
公开(公告)日:2017-03-30
申请号:US15373335
申请日:2016-12-08
CPC分类号: A61B5/4851 , A61B5/0066 , A61B5/0084 , A61B5/6852 , A61F2/91 , A61L29/146 , A61L29/18 , A61L31/146 , A61L31/18 , G01B9/02091 , H01L21/0337 , H01L21/31144
摘要: An endoprosthesis, a method for imaging an endoprosthesis, a method of making an endoprosthesis involve a polymeric substrate that has been modified to have voids embedded within the substrate. The voids are sized to scatter optical radiation from within the substrate so that an optical coherence tomography (OCT) image can be obtained in which an interior region of the substrate can be easily differentiated from empty space and other structures that surround the endoprosthesis. The voids allow for OCT visualization of the polymeric substrate which may be difficult to visualize by other methods such as fluoroscopy.
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公开(公告)号:US20160375179A1
公开(公告)日:2016-12-29
申请号:US14750913
申请日:2015-06-25
CPC分类号: A61L31/06 , A61F2/844 , A61F2/915 , A61F2002/91558 , A61F2210/0004 , A61F2210/0076 , A61F2230/0069 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/608 , A61L2420/02 , A61L2420/08 , C08L67/04
摘要: Methods of fabricating a stent are disclosed including forming a primer layer on a surface of the scaffold including a first polylactide polymer. The primer layer includes a second polylactide polymer and is free of a therapeutic agent. The scaffold with the primer layer is thermally treated to condition the scaffold. A therapeutic layer is formed over the primer layer and the therapeutic layer includes the second polylactide polymer and a drug. The scaffold is crimped and the primer layer improves adhesion of the therapeutic layer to the scaffold and reduces or prevents damage to the therapeutic layer during crimping.
摘要翻译: 公开了制造支架的方法,包括在包括第一聚丙交酯聚合物的支架表面上形成底漆层。 底漆层包括第二聚丙交酯聚合物并且不含治疗剂。 将具有底漆层的支架进行热处理以调节支架。 在底漆层上形成治疗层,治疗层包括第二聚丙交酯聚合物和药物。 支架被卷曲,并且底漆层改善治疗层对支架的粘附,并减少或防止在卷曲期间对治疗层的损伤。
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公开(公告)号:US20180272044A1
公开(公告)日:2018-09-27
申请号:US15996355
申请日:2018-06-01
CPC分类号: A61L31/148 , A61F2/88 , A61F2/90 , A61F2/966 , A61F2002/826 , A61F2002/9517 , A61F2250/0018 , A61F2250/0031 , A61F2250/0039 , A61F2250/0067 , A61L31/128 , C08L67/04
摘要: A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.
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公开(公告)号:US09757258B2
公开(公告)日:2017-09-12
申请号:US14859170
申请日:2015-09-18
发明人: Rommel Lumauig , Stephen D. Pacetti , Ni Ding , Joel Harrington , Xiao Ma , James P. Oberhauser , Jill McCoy , Chad J. Abunassar , Senthil Eswaran , Diem Ta
IPC分类号: A61F2/82 , A61F2/91 , A61F2/915 , C08G63/08 , B29C71/02 , A61L31/06 , A61L31/14 , B29K67/00 , B29L31/00 , B29C35/04 , B29C35/08
摘要: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.
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公开(公告)号:US09700443B2
公开(公告)日:2017-07-11
申请号:US14738710
申请日:2015-06-12
发明人: Rommel Lumauig , Joel Harrington , Chad Abunassar , David D. Hart , Cornel I. Ciurea , Mark A. Ritchie , Jay A. King , Jill McCoy
IPC分类号: A61F2/82 , A61F2/915 , A61F2/89 , A61F2/844 , B21J15/02 , B21J15/14 , A61F2/86 , B21J15/04 , A61F2/30
CPC分类号: A61F2/915 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2002/3008 , A61F2002/91575 , A61F2210/0014 , A61F2220/0033 , A61F2230/0026 , A61F2230/0069 , A61F2240/001 , A61F2250/0098 , B21J15/02 , B21J15/04 , B21J15/14 , Y10T29/49993
摘要: A scaffold includes a radiopaque marker connected to a strut. The marker is retained within the strut by a head at one or both ends. The marker is attached to the strut by a process that includes forming a rivet from a radiopaque bead and attaching the rivet to the marker including deforming the rivet to enhance resistance to dislodgement during crimping or balloon expansion. The strut has a thickness of about 100 microns.
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公开(公告)号:US20160081827A1
公开(公告)日:2016-03-24
申请号:US14859170
申请日:2015-09-18
发明人: Rommel Lumauig , Stephen D. Pacetti , Ni Ding , Joel Harrington , Xiao Ma , James P. Oberhauser , Jill McCoy , Chad J. Abunassar , Senthil Eswaran , Diem Ta
CPC分类号: A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2210/0004 , A61F2230/0069 , A61L31/06 , A61L31/14 , A61L31/148 , B29C71/0009 , B29C71/02 , B29C2035/046 , B29C2035/048 , B29C2035/0811 , B29C2035/0822 , B29C2035/0855 , B29C2035/0861 , B29C2071/022 , B29K2067/046 , B29K2995/006 , B29L2031/7534 , C08G63/08 , C08L67/04
摘要: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.
摘要翻译: 公开的方法包括当支架从卷曲状态展开到展开状态(例如标称展开直径)时,热处理支架以增加支架的径向强度。 热处理可以进一步维持或增加支架在膨胀超过公称直径时的膨胀能力。
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公开(公告)号:US20150081000A1
公开(公告)日:2015-03-19
申请号:US14484943
申请日:2014-09-12
CPC分类号: A61L31/148 , A61F2/88 , A61F2/90 , A61F2/966 , A61F2002/826 , A61F2002/9517 , A61F2250/0018 , A61F2250/0031 , A61F2250/0039 , A61F2250/0067 , A61L31/128 , C08L67/04
摘要: A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.
摘要翻译: 至少部分由生物可吸收材料制成的编织聚合物支架部署在使用推拉机构部署支架的导管上。 药物涂层设置在支架上。 还公开了导管上的多个支架段。
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公开(公告)号:US11478370B2
公开(公告)日:2022-10-25
申请号:US16789217
申请日:2020-02-12
发明人: Rommel Lumauig , Joel Harrington , Chad Abunassar , David D. Hart , Cornel I. Ciurea , Mark A. Ritchie , Jay A. King , Jill McCoy
IPC分类号: A61F2/91 , A61F2/915 , A61F2/89 , A61F2/844 , B21J15/02 , B21J15/14 , A61F2/86 , B21J15/04 , A61F2/30
摘要: A scaffold includes a radiopaque marker connected to a strut. The marker is retained within the strut by a head at one or both ends. The marker is attached to the strut by a process that includes forming a rivet from a radiopaque bead and attaching the rivet to the marker including deforming the rivet to enhance resistance to dislodgement during crimping or balloon expansion. The strut has a thickness of about 100 microns.
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