公开(公告)号：US20180291403A1

公开(公告)日：2018-10-11

申请号：US15927622

申请日：2018-03-21

Applicant: AJINOMOTO CO., INC.

Inventor： Yasushi Hoshino ,  Akiko Matsudaira ,  Mika Moriya ,  Nobuhisa Nitta ,  Yosuke Nishio

IPC: C12P7/04 ,  C12P5/00 ,  C12N15/70 ,  C12N15/74 ,  C12N9/88

Abstract: The present invention describes an efficient method for producing linalool. The present invention provides a method for producing linalool, the method including culturing a microorganism expressing linalool synthase in a culture medium to produce linalool. The present invention also describes a microorganism able to express linalool synthase and efficiently produce linalool.

公开(公告)号：US10941420B2

公开(公告)日：2021-03-09

申请号：US15927573

申请日：2018-03-21

Applicant: AJINOMOTO CO., INC.

Inventor： Yasushi Hoshino ,  Yoshiko Inoue ,  Mika Moriya ,  Akiko Matsudaira ,  Yosuke Nishio

IPC: C12P7/04 ,  C12N15/74 ,  C12N9/00 ,  C12N15/09

Abstract: The present invention provides a composition containing linalool, wherein the composition contains a high amount of either enantiomer R-linalool or S-linalool, and has a high content rate of linalool. The present invention also provides a production method for producing the composition. The present invention further provides a composition containing volatile components including linalool, in which a content of linalool in a total content of the volatile components in the composition is 60% or more, and the linalool is present as R-linalool or S-linalool in an amount of 50% or more of the enantiomer, and a production method therefor.

公开(公告)号：US20180291402A1

公开(公告)日：2018-10-11

申请号：US15927573

申请日：2018-03-21

Applicant: AJINOMOTO CO., INC.

Inventor： Yasushi Hoshino ,  Yoshiko Inoue ,  Mika Moriya ,  Akiko Matsudaira ,  Yosuke Nishio

IPC: C12P7/04 ,  C12N15/74

Abstract: The present invention provides a composition containing linalool, wherein the composition contains a high amount of either enantiomer R-linalool or S-linalool, and has a high content rate of linalool. The present invention also provides a production method for producing the composition. The present invention further provides a composition containing volatile components including linalool, in which a content of linalool in a total content of the volatile components in the composition is 60% or more, and the linalool is present as R-linalool or S-linalool in an amount of 50% or more of the enantiomer, and a production method therefor.

公开(公告)号：US20230212503A1

公开(公告)日：2023-07-06

申请号：US18063181

申请日：2022-12-08

Applicant: AJINOMOTO CO., INC.

Inventor： Nobuhisa Nitta ,  Hiroaki Fukada ,  Kazutaka Shimbo ,  Akiko Matsudaira ,  Toshiki Watanabe ,  Yoshihiro Usuda

IPC: C12N1/14

CPC classification number: C12N1/145 ,  C12N2501/734

Abstract: A method for producing a protein is provided. An objective protein is produced by culturing in a culture medium Talaromyces cellulolyticus having an objective protein-producing ability, which has been modified so that the activity of a Pep4 protein is reduced.

公开(公告)号：US10563234B2

公开(公告)日：2020-02-18

申请号：US15361645

申请日：2016-11-28

Applicant: AJINOMOTO CO., INC.

Inventor： Hidetaka Doi ,  Akiko Matsudaira ,  Yoshihiro Usuda

IPC: C12P13/04 ,  C12P13/08

Abstract: A method for producing an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, wherein the bacterium has been modified so that the activity of aconitase is increased, or the activities of aconitase and acetaldehyde dehydrogenase are increased, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

公开(公告)号：US20170073714A1

公开(公告)日：2017-03-16

申请号：US15361645

申请日：2016-11-28

Applicant: AJINOMOTO CO., INC.

Inventor： Hidetaka Doi ,  Akiko Matsudaira ,  Yoshihiro Usuda

IPC: C12P13/08

CPC classification number: C12P13/08 ,  C12N15/00 ,  C12N15/09

Abstract: A method for producing an L-amino acid is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, wherein the bacterium has been modified so that the activity of aconitase is increased, or the activities of aconitase and acetaldehyde dehydrogenase are increased, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

Abstract translation: 提供了L-氨基酸的制造方法。 通过培养属于肠杆菌科的细菌并具有L-氨基酸生产能力来生产L-氨基酸，其中细菌已被修饰，使得乌头酸酶的活性增加，或者乌头酸酶和乙醛脱氢酶的活性 在培养基中增加，并从细菌的培养基或细胞中收集L-氨基酸。