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    IMPLANTABLE MATERIALS
    2.
    发明申请
    IMPLANTABLE MATERIALS 审中-公开
    可植入材料

    公开(公告)号：US20140242258A1

    公开(公告)日：2014-08-28

    申请号：US14271292

    申请日：2014-05-06

    Applicant: Allergan, Inc.

    Inventor： Alexei Goraltchouk ,  Jordan Thompson ,  Miram M. Abiad ,  Kevin A. Ma

    IPC: A61L27/00

    CPC classification number: A61L27/00 ,  A61F2/12 ,  A61L27/18 ,  A61L27/56 ,  A61L2430/04 ,  C08L83/04

    Abstract: A textured breast implant is provided which generally includes a fluid fillable elastomeric shell having a texture defined by struts, for example, hollow struts, defining interconnected open cells. Methods of making the texture include applying a silicone dispersion to a base material and removing the base material from the coating to form a silicone-based structure comprising struts defining interconnected open cells, said struts including internal surfaces defining cavities within the struts. The method may further include the step of contacting the silicone based structure having cavities with a silicone dispersion to cause the silicone to enter and fill the cavities.

    Abstract translation: 提供纹理化的乳房植入物，其通常包括具有由支柱（例如，定义互连的开放细胞）的中空支柱限定的纹理的流体可填充的弹性体外壳。 制造纹理的方法包括将硅氧烷分散体施加到基材上并从涂层中除去基材以形成包含限定互连的开放电池的支柱的硅氧烷基结构，所述支柱包括限定支柱内的空腔的内表面。 该方法还可以包括使具有空腔的硅氧烷基结构与硅氧烷分散体接触以使硅酮进入和填充空腔的步骤。

    INTRAGASTRIC BALLOON SHELL MATERIALS AND CONSTRUCTION
    3.
    发明申请
    INTRAGASTRIC BALLOON SHELL MATERIALS AND CONSTRUCTION 审中-公开
    内部气囊材料和结构

    公开(公告)号：US20140066968A1

    公开(公告)日：2014-03-06

    申请号：US14075698

    申请日：2013-11-08

    Applicant: Allergan, Inc.

    Inventor： Elizabeta Pavlovic ,  Jordan Thompson ,  Loantrang Dang ,  Alexei Goraltchouk

    IPC: A61F5/00

    CPC classification number: A61F5/003 ,  A61F5/0036 ,  A61L31/042 ,  A61L31/048 ,  A61L31/06 ,  A61L31/14 ,  C08L79/02 ,  C08L67/04 ,  C08L1/28 ,  C08L5/08 ,  C08L23/16

    Abstract: An intragastric balloon with a 12-month lifespan. The intragastric balloon has a shell made of a material with as good as or better than initial mechanical properties of previous materials; i.e. higher ultimate tensile strength (UTS) and elongation at break (Eb), lower stiffness (K), higher acid stability, and improved resistance to infection. The new materials in particular provide improved acid resistance. These new materials produce a device that has reduced adverse events and a longer lifespan in vivo. The materials may form the entire wall of the shell or may form just a barrier layer coupled with a scaffold layer of a different material.

    Abstract translation: 一个12个月的寿命的胃内气球。 胃内球囊具有由先前材料的初始机械性能好或优于原材料的材料制成的外壳; 即更高的极限拉伸强度（UTS）和断裂伸长率（Eb），较低的刚度（K），较高的酸稳定性和改善的抗感染性。 新材料特别提供改善的耐酸性。 这些新材料产生的体内减少不良事件和更长使用寿命的装置。 材料可以形成壳的整个壁，或者可以形成仅与不同材料的支架层结合的阻挡层。

    TEXTURED PROSTHESIS WITH REDUCED CAPSULAR CONTRACTURE RESPONSE
    5.
    发明申请
    TEXTURED PROSTHESIS WITH REDUCED CAPSULAR CONTRACTURE RESPONSE 审中-公开
    具有减少CAPSULAR合同反应的纹理预测

    公开(公告)号：US20140005784A1

    公开(公告)日：2014-01-02

    申请号：US13923231

    申请日：2013-06-20

    Applicant: Allergan, Inc.

    Inventor： Dennis E. Van Epps ,  Barbara Nofrey ,  Jordan Thompson

    IPC: A61F2/12

    CPC classification number: A61F2/12 ,  A61L27/24

    Abstract: A method of augmenting or reconstructing a breast of a patient, the method comprising the step of implanting into the patient, a breast prosthesis, having surface characteristics directed at reducing collagen alignment in periprosthetic tissue.

    Abstract translation: 一种增加或重建患者乳房的方法，所述方法包括向患者植入具有针对减少假体周围组织中的胶原排列的表面特征的乳房假体的步骤。

    TEXTURED PROSTHESIS WITH REDUCED CAPSULAR CONTRACTURE RESPONSE
    6.
    发明申请
    TEXTURED PROSTHESIS WITH REDUCED CAPSULAR CONTRACTURE RESPONSE 审中-公开
    具有减少CAPSULAR合同反应的纹理预测

    公开(公告)号：US20140005783A1

    公开(公告)日：2014-01-02

    申请号：US13923227

    申请日：2013-06-20

    Applicant: Allergan, Inc.

    Inventor： Dennis E. Van Epps ,  Barbara Nofrey ,  Jordan Thompson

    IPC: A61F2/12

    CPC classification number: A61F2/12 ,  A61L27/18 ,  A61L27/56 ,  A61L2430/04 ,  C08L83/04

    Abstract: Biocompatible materials are provided which include various textured surfaces, which when such materials are implanted in a human being, for example, as a component of a breast prosthesis, provide for tissue integration, reduce the linear alignment of collagen fibers around the implant and reduce or eliminate the potential for capsular contracture.

    Abstract translation: 提供了生物相容性材料，其包括各种纹理表面，当将这种材料植入人体中时，例如作为乳房假体的组分，提供组织整合，减少胶原纤维在植入物周围的线性排列，并减少或 消除荚膜挛缩的可能性。

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