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Patent Agency Ranking
1.发明申请Method for Producing L-Amino Acids Using Bacteriua of the Enterobacteriaceae Family 审中-公开使用肠杆菌科的细菌生产L-氨基酸的方法公开(公告)号：US20140287472A1
公开(公告)日：2014-09-25
申请号：US14301438
申请日：2014-06-11
Applicant: AJINOMOTO CO., INC.
Inventor： Konstantin Vyacheslavovich Rybak , Ekaterina Aleksandrovna Slivinskaya , Ekaterina Alekseevna Savrasova , Valeriy Zavenovich Akhverdian , Elena Vitalievna Klyachko , Sergei Vladimirovich Mashko , Vera Georgievna Doroshenko , Larisa Gotlibovna Airikh , Tatyana Viktorovna Leonova , Mikhail Markovich Gusyatiner , Elvira Borisovna Voroshilova , Yury Ivanovich Kozlov , Yoshihiko Hara , Takuji Ueda
Abstract: There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.
Abstract translation: 公开了使用肠杆菌科的细菌生产L-氨基酸的方法，例如L-苏氨酸，L-赖氨酸，L-组氨酸，L-苯丙氨酸，L-精氨酸或L-谷氨酸，其中细菌 已被修饰以增强D-木糖通透酶的活性。
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公开(公告)号：US08753849B2
公开(公告)日：2014-06-17
申请号：US13774153
申请日：2013-02-22
Applicant: Ajinomoto Co., Inc.
Inventor： Yury Ivanovich Kozlov , Akito Chinen , Hiroshi Izui , Yoshihiko Hara , Hisashi Yasueda , Konstantin Vyacheslavovich Rybak , Ekaterina Aleksandrovna Slivinskaya , Joanna Yosifovna Katashkina
IPC: C12P13/14
CPC classification number: C12P13/24 , C12N9/88 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/62 , C12P13/06 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12Y401/02009 , C12Y401/02022
Abstract: The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
Abstract translation: 本发明提供一种具有生产乙酰辅酶A的有用代谢物的能力，例如L-谷氨酸，L-谷氨酰胺，L-脯氨酸，L-精氨酸，L-亮氨酸，L-半胱氨酸，琥珀酸酯 和聚羟基丁酸酯，其中所述细菌被修饰，使得D-木酮糖-5-磷酸磷酸酮糖苷酶和/或果糖-6-磷酸磷酸酮醇酶的活性增强。 本发明还提供了使用该细菌生产有用代谢物的方法。
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公开(公告)号：US08969048B2
公开(公告)日：2015-03-03
申请号：US14268110
申请日：2014-05-02
Applicant: Ajinomoto Co., Inc.
Inventor： Yury Ivanovich Kozlov , Akito Chinen , Hiroshi Izui , Yoshihiko Hara , Hisashi Yasueda , Konstantin Vyacheslavovich Rybak , Ekaterina Aleksandrovna Slivinskaya , Joanna Yosifovna Katashkina
IPC: C12P13/24 , C12N9/88 , C12P7/46 , C12P7/62 , C12P13/06 , C12P13/10 , C12P13/14 , C12P7/44 , C12P13/12 , C12P13/20 , C12P7/42
CPC classification number: C12P13/24 , C12N9/88 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/62 , C12P13/06 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12Y401/02009 , C12Y401/02022
Abstract: The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
Abstract translation: 本发明提供一种具有生产乙酰辅酶A的有用代谢物的能力，例如L-谷氨酸，L-谷氨酰胺，L-脯氨酸，L-精氨酸，L-亮氨酸，L-半胱氨酸，琥珀酸酯 和聚羟基丁酸酯，其中所述细菌被修饰，使得D-木酮糖-5-磷酸磷酸酮糖苷酶和/或果糖-6-磷酸磷酸酮醇酶的活性增强。 本发明还提供了使用该细菌生产有用代谢物的方法。
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公开(公告)号：US20140242643A1
公开(公告)日：2014-08-28
申请号：US14268110
申请日：2014-05-02
Applicant: AJINOMOTO CO., INC.
Inventor： Yury Ivanovich Kozlov , Akito Chinen , Hiroshi Izui , Yoshihiko Hara , Hisashi Yasueda , Konstantin Vyacheslavovich Rybak , Ekaterina Aleksandrovna Slivinskaya , Joanna Yosifovna Katashkina
CPC classification number: C12P13/24 , C12N9/88 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/62 , C12P13/06 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12Y401/02009 , C12Y401/02022
Abstract: The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
Abstract translation: 本发明提供一种具有生产乙酰辅酶A的有用代谢物的能力，例如L-谷氨酸，L-谷氨酰胺，L-脯氨酸，L-精氨酸，L-亮氨酸，L-半胱氨酸，琥珀酸酯 和聚羟基丁酸酯，其中所述细菌被修饰，使得D-木酮糖-5-磷酸磷酸酮糖苷酶和/或果糖-6-磷酸磷酸酮醇酶的活性增强。 本发明还提供了使用该细菌生产有用代谢物的方法。
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公开(公告)号：US20130157321A1
公开(公告)日：2013-06-20
申请号：US13774153
申请日：2013-02-22
Applicant: Ajinomoto Co., Inc.
Inventor： Yury Ivanovich Kozlov , Akito Chinen , Hiroshi Izui , Yoshihiko Hara , Hisashi Yasueda , Konstantin Vyacheslavovich Rybak , Ekaterina Aleksandrovna Slivinskaya , Joanna Yosifovna Katashkina
CPC classification number: C12P13/24 , C12N9/88 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/62 , C12P13/06 , C12P13/10 , C12P13/12 , C12P13/14 , C12P13/20 , C12Y401/02009 , C12Y401/02022
Abstract: The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
Abstract translation: 本发明提供一种具有生产乙酰辅酶A的有用代谢物的能力，例如L-谷氨酸，L-谷氨酰胺，L-脯氨酸，L-精氨酸，L-亮氨酸，L-半胱氨酸，琥珀酸酯 和聚羟基丁酸酯，其中所述细菌被修饰，使得D-木酮糖-5-磷酸磷酸酮糖苷酶和/或果糖-6-磷酸磷酸酮醇酶的活性增强。 本发明还提供了使用该细菌生产有用代谢物的方法。
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