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6 条记录 (耗时 0.019 秒)

    Process for preparing optically active carboxylic acids and antipode esters thereof
    1.
    发明授权
    Process for preparing optically active carboxylic acids and antipode esters thereof 失效
    光学活性羧酸及其对映体酯的制备方法

    公开(公告)号：US4629701A

    公开(公告)日：1986-12-16

    申请号：US627093

    申请日：1984-07-02

    申请人： Akihiro Sakimae ,  Yuri Kagawa ,  Ryozo Numazawa ,  Hisao Onishi

    发明人： Akihiro Sakimae ,  Yuri Kagawa ,  Ryozo Numazawa ,  Hisao Onishi

    IPC分类号： C12P11/00 ,  C12P41/00

    CPC分类号： C12P41/00 ,  C12P11/00

    摘要： Organic carboxylic acid ester represented by the formula (II): ##STR1## wherein R.sub.1 is an alkyl, an aralkyl or an aryl group; R.sub.2 is an alkyl group; R.sub.3 is an alkyl group; n is 1 or 2, are synthesized in racemic form, and then the acid ester (II) is treated with a source containing enzyme capable of rearranging with or without asymmetrically hydrolyzing ester bond until either a d-form or 1-form optically active carboxylic acid ester represented by the formula (II) with or without the antipode acid thereof is produced.

    摘要翻译： 由式（II）表示的有机羧酸酯：其中R 1是烷基，芳烷基或芳基; R2是烷基; R3是烷基; n为1或2，以外消旋形式合成，然后用含有酶的酶处理酸酯（II），其能够或不具有不对称水解的酯键重排，直到d型或1-型光学活性羧基 制备了具有或不具有对映体酸的由式（II）表示的酸酯。

    Method of producing hyaluronic acid
    3.
    发明授权
    Method of producing hyaluronic acid 失效
    生产透明质酸的方法

    公开(公告)号：US4885244A

    公开(公告)日：1989-12-05

    申请号：US104219

    申请日：1987-10-05

    申请人： Takao Miyamori ,  Ryozo Numazawa ,  Akihiro Sakimae ,  Hisao Onishi

    发明人： Takao Miyamori ,  Ryozo Numazawa ,  Akihiro Sakimae ,  Hisao Onishi

    IPC分类号： C12P19/04 ,  C08B37/08 ,  C12N1/20 ,  C12P19/26 ,  C12R1/46

    CPC分类号： C08B37/0072 ,  C12P19/26 ,  Y10T436/188

    摘要： High molecular weight hyaluronic acid can be efficiently produced by incorporating one or more compounds having at least one aromatic ring to which one or more hydroxyl groups are attached into a medium for producing hyaluronic acid by a bacterium capable of producing hyaluronic acid. By using this method, a sufficient amount of hyaluronic acid can be easily obtained without decomposing the high molecular structure of hyaluronic acid so that the process for isolating and purifying hyaluronic acid from the medium can be simplified.

    摘要翻译： 高分子量透明质酸可以通过将一种或多种具有至少一个芳环的化合物（其中一个或多个羟基被连接到用于产生透明质酸的细菌的培养基中）而被能够产生透明质酸的细菌产生。 通过使用该方法，可以容易地获得足够量的透明质酸，而不会分解透明质酸的高分子结构，从而可以简化从培养基中分离和纯化透明质酸的方法。

    Biochemical process for purifying contaminated water
    4.
    发明授权
    Biochemical process for purifying contaminated water 失效
    净化污水的生化工艺

    公开(公告)号：US4746435A

    公开(公告)日：1988-05-24

    申请号：US470138

    申请日：1983-02-28

    申请人： Hisao Onishi ,  Ryozo Numazawa

    发明人： Hisao Onishi ,  Ryozo Numazawa

    IPC分类号： C02F3/34 ,  B01D53/22 ,  B01D53/84 ,  C02F3/06 ,  C02F3/10 ,  C02F3/12 ,  C02F3/20 ,  C02F3/30 ,  C02F3/04

    CPC分类号： C02F3/1263 ,  B01D53/22 ,  B01D53/84 ,  C02F3/102 ,  C02F3/208 ,  C02F3/302 ,  Y02W10/15 ,  Y10S210/903

    摘要： A process for treating contaminated water containing BOD sources and nitrogen sources, which comprises supplying oxygen or oxygen-containing gas from one side of a gas-permeable membrane to grow microorganisms including aerobic bacteria and anaerobic bacteria on the other side of the gas-permeable membrane, and performing decomposition of the BOD sources and nitrification and denitrification simultaneously by the action of these microorganisms. Especially good results are obtained when a membrane composed of porous hollow fibers is used as the gas-permeable membrane.

    摘要翻译： 一种用于处理含有BOD源和氮源的污水的方法，其包括从透气膜的一侧供应氧气或含氧气体，以在气体渗透膜的另一侧生长包括需氧细菌和厌氧细菌的微生物 ，并通过这些微生物的作用同时进行BOD源的分解和硝化反硝化。 当使用由多孔中空纤维构成的膜作为气体透过膜时，获得了特别好的结果。

    Preparation of immobilized enzymes of microorganisms
    6.
    发明授权
    Preparation of immobilized enzymes of microorganisms 失效
    微生物固定化酶的制备

    公开(公告)号：US4276381A

    公开(公告)日：1981-06-30

    申请号：US60907

    申请日：1979-07-26

    申请人： Akihiro Sakimae ,  Hisao Onishi

    发明人： Akihiro Sakimae ,  Hisao Onishi

    IPC分类号： C12N9/82 ,  C12N1/04 ,  C12N11/04 ,  C12P19/14 ,  G01N27/327 ,  C12N11/12

    CPC分类号： C12P19/14 ,  C12N1/04 ,  C12N11/04

    摘要： Immobilized enzymes or microorganisms are prepared by dispersing lumps of ice containing an enzyme or microorganism in an organic solvent having a water-insoluble high-molecular weight substance dissolved therein, and then removing the organic solvent to entrap the ice lumps in the water-insoluble high-molecular weight substance. Deactivation of the enzyme or microorganism by the organic solvent is prevented by the enzyme or microorganism being entrapped in the lumps of ice.

    摘要翻译： 固定的酶或微生物通过将含有酶或微生物的冰块块溶解在其中溶解有不溶于水的高分子量物质的有机溶剂中而制备，然后除去有机溶剂以将冰块截留在不溶于水的高温 分子量物质。 通过酶或微生物被捕获在冰块中来防止酶或微生物被有机溶剂的失活。