Method of purifying ferment-produced riboflavin
    6.
    发明授权
    Method of purifying ferment-produced riboflavin 失效
    净化发酵的RIBOFLAVIN的方法

    公开(公告)号:US5210023A

    公开(公告)日:1993-05-11

    申请号:US724056

    申请日:1991-07-01

    IPC分类号: C07D475/14 C12P17/18

    CPC分类号: C07D475/14

    摘要: A method of purifying ferment-produced riboflavin, wherein the impure riboflavin is suspended in water or dilute aqueous acid, and the suspension is heated at a temperature of from 75.degree. to 130.degree. C. for from 0.3 to 3 hours with stirring, during which time crystal transformation takes place, after which the mixture is cooled and the purified product is isolated in known manner.

    摘要翻译: 一种纯化发酵生产的核黄素的方法,其中不纯的核黄素悬浮在水中或稀释酸水溶液,悬浮液在75-130℃的温度下搅拌加热0.3-3小时,在此期间 发生时间晶体转变,然后将混合物冷却,以已知方式分离纯化产物。

    Method for the production of riboflavin of modification b/c in granular form
    10.
    发明授权
    Method for the production of riboflavin of modification b/c in granular form 失效
    用于生产颗粒形式的改性b / c的核黄素的方法

    公开(公告)号:US07329748B2

    公开(公告)日:2008-02-12

    申请号:US10552137

    申请日:2004-04-07

    IPC分类号: C07D487/04

    CPC分类号: C07D475/14 A23L33/15

    摘要: The present invention relates to an improved process for preparing riboflavin of the B/C modification in granule form. Furthermore, the invention relates to the riboflavin preparation process wherein riboflavin of the A modification is (a) dissolved in aqueous mineral acid without treating the resulting riboflavin solution with activated carbon, (b) precipitated directly afterwards, steps (a) and (b) being carried out at a temperature in the range from 5 to 15° C., and (c) dried by fluidized bed granulation; and wherein the riboflavin does not come into contact with the aqueous mineral acid solvent for longer than on average 4 hours.

    摘要翻译: 本发明涉及一种制备颗粒形式的B / C改性核黄素的改进方法。 此外,本发明涉及核黄素制备方法,其中A修饰的核黄素是(a)溶解在无机酸水溶液中,而不用活性炭处理所得的核黄素溶液,(b)直接沉淀,步骤(a)和(b) 在5至15℃的温度下进行,(c)通过流化床造粒干燥; 并且其中所述核黄素不与无机酸水溶液接触长于平均4小时。