摘要:
An electromagnetic logging tool is disclosed that includes a support; and at least one four-coil array disposed on the support, wherein the at least one four-coil array comprises: a transmitter, a bucking coil, a receiver, and a trim coil. A method for balancing an induction array is disclosed that includes applying an alternating current to a transmitter of the induction array that comprises the transmitter, a bucking coil and a receiver; measuring a mutual coupling between the transmitter and the receiver; and adding an extra bucking coil, if the mutual coupling exceeds a selected criterion.
摘要:
The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.
摘要:
A fuel filler neck assembly having a uniform hemmed connection between an outer funnel portion and an inner funnel portion. The outer funnel portion is typically defined by an offset-expanded cylinder and sidewalls of varying thickness. The inner funnel portion includes sidewalls that have an internal thread, which is configured to mate with the threads of a gas cap. A hemmed connection is used to join one end of the outer funnel portion to one end of the inner funnel portion. The sidewalls at one end of the outer funnel portion are folded or bent inwardly and around the rim portion to define a curled portion. A tooling assembly for producing a uniform hemmed connection between one end of the outer funnel portion and one end of the inner funnel portion. A method of producing a uniform hemmed connection between portions of a fuel filler neck.
摘要:
Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalogue the genetic changes that occur during tumorigenesis, we isolated DNA from 11 breast and 11 colorectal tumors and determined the sequences of the genes in the Reference Sequence database in these samples. Based on analysis of exons representing 20,857 transcripts from 18,191 genes, we conclude that the genomic landscapes of breast and colorectal cancers are composed of a handful of commonly mutated gene “mountains” and a much larger number of gene “hills” that are mutated at low frequency. We describe statistical and bioinformatic tools that may help identify mutations with a role in tumorigenesis. These results have implications for understanding the nature and heterogeneity of human cancers and for using personal genomics for tumor diagnosis and therapy.
摘要:
A well logging tool includes an induction array stack disposed on a mandrel; an electronic module stack disposed adjacent the induction array stack along a longitudinal axis of the well logging tool; and a shallow electrode array arranged on a housing disposed around the electronic module stack, wherein the induction array stack comprises a transmitter antenna, a first receiver antenna, and a second receiver antenna spaced apart from each other along the longitudinal axis of the well logging tool, the second receiver antenna being disposed between the transmitter antenna and the first receiver antenna.
摘要:
A cover for a food holder includes a body having an inner surface and an outer surface, the body having at least one aperture provided therein, the at least one aperture providing communication between the inner surface and the outer surface; and a serving implement having a first portion extending through the aperture along one of the inner and outer surfaces, and a second portion extending along the other of the inner and outer surfaces.
摘要:
A timing system is disclosed for use in a wireless communication system that includes wireless transceiver and a digital baseband processing system. The timing system includes a primary clock generation system that provides a low frequency clock that is used as the reference clock for a digital signal processing system, which generates low frequency timing signals, and a secondary clock generation system that provides a high frequency clock that is used by the wireless transceiver to produce high resolution timing signals to control the timing of the wireless transceiver. The high resolution timing signals are commenced responsive to a low resolution timing signal.