摘要:
Compounds of the formula are disclosed as Mnk2 inhibitors which are useful for the treatment and prevention of metabolic disorders such as obesity and diabetes.
摘要:
The invention relates to aminopurine derivatives useful in treating disorders that are mediated by adenosine receptor function, including neurodegenerative diseases and inflammation. The compounds are of the general formula:
摘要:
The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
摘要:
The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
摘要:
The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
摘要:
A system and method for performing phase-locked loop is disclosed. The system includes phase frequency detector circuitry, charge pump circuitry having first current mirror circuitry and second current mirror circuitry, loop filter circuitry, and voltage controlled oscillator circuitry. The phase frequency detector circuitry generates an up signal and a down signal based on the phase difference of an input signal and a feedback signal. The charge pump circuitry includes the first current mirror circuitry and the second mirror circuitry and generates a charge pump output signal based on the up and down signals. The loop filter circuitry generates a filtered control signal based on the charge pump output signal. The voltage controlled oscillator circuitry generates the feedback signal with a repeating waveform based on the filtered control signal.
摘要:
An integrated circuit includes first circuitry and sleep transistor circuitry. The first circuitry receives input signals and processes the input signals. The first circuitry also retains data in a sleep state that has low leakage. The sleep transistor circuitry is coupled to the first circuitry and receives a sleep signal. The sleep circuitry reduces power consumption of the first circuitry in the sleep state to have low leakage based on the sleep signal while retaining the data in the first circuitry.
摘要:
A system and method for performing phase-locked loop is disclosed. The system includes phase frequency detector circuitry, charge pump circuitry having first current mirror circuitry and second current mirror circuitry, loop filter circuitry, and voltage controlled oscillator circuitry. The phase frequency detector circuitry generates an up signal and a down signal based on the phase difference of an input signal and a feedback signal. The charge pump circuitry includes the first current mirror circuitry and the second mirror circuitry and generates a charge pump output signal based on the up and down signals. The loop filter circuitry generates a filtered control signal based on the charge pump output signal. The voltage controlled oscillator circuitry generates the feedback signal with a repeating waveform based on the filtered control signal.
摘要:
One or more water-soluble capsules (3) containing a detergent composition in combination with a package (1) containing the one or more water-soluble capsules, characterised in that the package is formed from a material which has a Moisture Vapour Transfer Rate (M.V.T.R) of between 0.25 g/m2/day to 10 g/m2/day at 38° C. and 90% relative humidity. The Moisture Vapour Transfer Rate is between 0.25 g/m2/day to 5 g/m2/day at 38° C. and 90% relative humidity. In a preferred embodiment, the package is self-standing by means of a collapsible base (16) portion which expands from a collapsed position to an expanded position when one or more capsules is/are placed on the base, and is collapsible when empty so as to make the package substantially flat.
摘要翻译:一种或多种含有洗涤剂组合物与含有一种或多种水溶性胶囊的包装(1)的组合的水溶性胶囊(3),其特征在于,所述包装由具有水分蒸气转移速率 MVTR)在38℃和90%相对湿度下为0.25g / m 2 /天至10g / m 2 /天。 在38℃和90%相对湿度下,水蒸汽转移速率为0.25g / m 2 /天至5g / m 2 /天。 在优选实施例中,当一个或多个胶囊被放置在基座上时,通过可折叠的底座(16)部分自动展开包装,该折叠部分从折叠位置膨胀到展开位置,并且当空的时可折叠 以使包装基本上平坦。
摘要:
An interface card includes a housing sized for reception by a host system, for example, a laptop computer. A sensor is movably connected to the housing and has a first position in which the sensor receives a relief object and generates an electronic representation of the relief object, and a second position in which the sensor is inactive. An interface module is coupled to the sensor and configured to provide for communications between the interface card and the host system.