公开(公告)号：US4788151A

公开(公告)日：1988-11-29

申请号：US912711

申请日：1986-09-29

申请人： Anthony F. Preziosi ,  Thaddeus Prusik

发明人： Anthony F. Preziosi ,  Thaddeus Prusik

IPC分类号： C07C275/20 ,  C07C275/28 ,  C07F1/00 ,  C07F3/00 ,  C07F19/00 ,  G01N31/22 ,  G01K11/16 ,  C07C127/15

CPC分类号： C07C275/28 ,  C07C275/20 ,  C07F1/005 ,  C07F19/005 ,  C07F3/003 ,  G01N31/22 ,  G01N31/222

摘要： Acetylenic complexes are disclosed that are useful as environmental indicating materials whereby exposure thereof to environmental stimuli induces a color change. These complexes contain at least one effective complexing metal and at least one acetylenic compound of the general formula:[R--(C"C).sub.a --(CH.sub.2).sub.b --(C"C).sub.c ].sub.2.dHXWherein a is 1 or 2, b is about 0-5; c is 0 or 1; with the proviso that when a is 1, b and c are 0, when a is 2, b is about 0-5 and c is 0 or 1; and R is --(CH.sub.2).sub.n -NHC(O)NHR'; wherein n is an integer of about 1 to 10; and R' is selected from the group consisting of: (a) hydrogen; (b) cycloalkyl; (c) alkenyl; (d) cycloalkenyl; (e) alkyl; (f) phenyl; (g) alkoxy; (h) alkoxy alkyl; and (i) alkoxycarbonylalkyl.

摘要翻译： 公开了作为环境指示材料有用的乙炔配合物，由此其暴露于环境刺激物引起颜色变化。 这些络合物含有至少一种有效的络合金属和至少一种具有以下通式的炔属化合物：[R-（C“C）a-（CH 2）b - （C”C）c] 2.dHX其中a为1或 2，b约为0-5; c为0或1; 条件是当a为1时，b和c为0，当a为2时，b为约0-5，c为0或1; 并且R是 - （CH 2）n -NHC（O）NHR'; 其中n为约1至10的整数; 和R'选自：（a）氢; （b）环烷基; （c）烯基; （d）环烯基; （e）烷基; （f）苯基; （g）烷氧基; （h）烷氧基烷基; 和（i）烷氧基羰基烷基。

公开(公告)号：US4892677A

公开(公告)日：1990-01-09

申请号：US683443

申请日：1984-12-19

申请人： Anthony F. Preziosi ,  Thaddeus Prusik ,  Ray H. Baughman

发明人： Anthony F. Preziosi ,  Thaddeus Prusik ,  Ray H. Baughman

IPC分类号： G01N31/22 ,  G07C1/00

CPC分类号： G07C1/00 ,  G01N31/229 ,  Y10S252/962 ,  Y10S428/913

摘要： A new process is described which is useful for producing novel articles of manufacture useful for monitoring the time-temperature history of perishable items. The process initially involves forming a solution comprised of a diacetylenic monomer and a solvent. The solution is frozen, and the frozen solution having crystalline diacetylenic monomer therein is irradiated to partially polymerize the diacetylenic monomer. Partial polymerization of the crystalline diacetylenic monomer admixed with frozen solvent results in the production of a novel article of manufacture having color. The novel article of manufacture is comprised of frozen solvent, diacetylenic monomer, and colored polydiacetylene. Due to the intensity of the color of the polydiacetylene, the entire article of manufacture appears to be colored.The colored article of manufacture may be attached to various perishables to monitor the shelf life of the perishables. upon exposure to temperatures above a critical temperature, the frozen solvent melts and extracts unreached monomer from the colored polymer, thereby causing a sharp color transition which indicates that the perishable should possibly be discarded.

摘要翻译： 描述了一种新方法，其可用于生产可用于监测易腐物品的时间 - 温度历史的新型制品。 该方法最初涉及形成由二乙炔单体和溶剂组成的溶液。 将溶液冷冻，照射其中具有结晶二炔单体的冷冻溶液以部分聚合二乙炔单体。 与冷冻溶剂混合的结晶二乙炔单体的部分聚合导致生产具有颜色的新型制品。 新型制品由冷冻溶剂，二乙炔单体和着色聚二乙炔组成。 由于聚二乙炔颜色的强度，整个制品似乎是有色的。 有色制品可以附着在各种易腐食品上，以监测易腐品的保质期。 在暴露于高于临界温度的温度下，冷冻的溶剂熔融并从着色聚合物中提取未接触的单体，从而引起明显的颜色转变，这表明易腐物质可能被丢弃。

公开(公告)号：US4789637A

公开(公告)日：1988-12-06

申请号：US912713

申请日：1986-09-29

申请人： Anthony F. Preziosi ,  Thaddeus Prusik

发明人： Anthony F. Preziosi ,  Thaddeus Prusik

IPC分类号： G01N31/22 ,  G01N33/02 ,  C07C127/15 ,  G01K11/14

CPC分类号： G01N33/02 ,  G01N31/22

摘要： A family of acetylenic complexes especially useful as environmental indicators is provided. The complexes include at least one complexing acid and one acetylenic compound of the formula:[R--(C.tbd.C).sub.a --(CH.sub.2).sub.b --(C.tbd.C).sub.c ].sub.2.dHXwherein, a is 1 or 2; b is about 0-5; c is 0 or 1; d is above 0 to about 2, with the proviso that when a is 1, b and c are 0, and when a is 2, b is about 0-5 and c is 0 or 1; and R is --(CH.sub.2)n--NHC(O)NHR'; wherein n is an integer of about 1 to 10; and R' is selected from a group consisting of hydrogen, cycloalkyl, alkenyl, cycloalkenyl, aklyl, phenyl, alkoxyl, alkoxylcarbonylalkyl, and X is a complexing acid.

摘要翻译： 提供了特别用作环境指标的炔属复合物系列。 络合物包括至少一种络合酸和一个下式的炔属化合物：[R-（C 3 B）C - （CH 2）b - （C 3 F 3）C] 2 dHX其中a为1或2; b约为0-5; c为0或1; d大于0至约2，条件是当a为1时，b和c为0，当a为2时，b为约0-5，c为0或1; 并且R是 - （CH 2）n -NHC（O）NHR'; 其中n为约1至10的整数; 并且R'选自氢，环烷基，烯基，环烯基，烷基，苯基，烷氧基，烷氧基羰基烷基，X是络合酸。

公开(公告)号：US4735745A

公开(公告)日：1988-04-05

申请号：US373955

申请日：1982-05-03

申请人： Anthony F. Preziosi ,  Thaddeus Prusik ,  Ray H. Baughman

发明人： Anthony F. Preziosi ,  Thaddeus Prusik ,  Ray H. Baughman

IPC分类号： G01N31/22 ,  G07C1/00 ,  G01N31/00 ,  G01D21/00

CPC分类号： G07C1/00 ,  G01N31/229 ,  Y10S252/962 ,  Y10S428/913

摘要： A new process is described which is useful for producing novel articles of manufacture useful for monitoring the time-temperature history of perishable items. The process initially involves forming a solution comprised of a diacetylenic monomer and a solvent. The solution is frozen, and the frozen solution having crystalline diacetylenic monomer therein is irradiated to partially polymerize the diacetylenic monomer. Partial polymerization of the crystalline diacetylenic monomer admixed with frozen solvent results in the production of a novel article of manufacture having color. The novel article of manufacture is comprised of frozen solvent, diacetylenic monomer, and colored polydiacetylene. Due to the intensity of the color of the polydiacetylene, the entire article of manufacture appears to be colored.The colored article of manufacture may be attached to various perishables to monitor the shelf life of the perishables. Upon exposure to temperatures above a critical temperature, the frozen solvent melts and extracts unreacted monomer from the colored polymer, thereby causing a sharp color transition which indicates that the perishable should possibly be discarded.

摘要翻译： 描述了一种新方法，其可用于生产可用于监测易腐物品的时间 - 温度历史的新型制品。 该方法最初涉及形成由二乙炔单体和溶剂组成的溶液。 将溶液冷冻，照射其中具有结晶二炔单体的冷冻溶液以部分聚合二乙炔单体。 与冷冻溶剂混合的结晶二乙炔单体的部分聚合导致生产具有颜色的新型制品。 新型制品由冷冻溶剂，二乙炔单体和着色聚二乙炔组成。 由于聚二乙炔颜色的强度，整个制品似乎是有色的。 有色制品可以附着在各种易腐食品上，以监测易腐品的保质期。 当暴露于高于临界温度的温度时，冷冻溶剂从着色聚合物中熔融并提取未反应的单体，从而引起明显的颜色转变，这表明易腐烂物可能被丢弃。

公开(公告)号：US08642807B2

公开(公告)日：2014-02-04

申请号：US13529605

申请日：2012-06-21

申请人： Ray H. Baughman ,  Lee J. Hall ,  Mikhail Kozlov ,  Dawn E. Smith ,  Thaddeus Prusik

发明人： Ray H. Baughman ,  Lee J. Hall ,  Mikhail Kozlov ,  Dawn E. Smith ,  Thaddeus Prusik

IPC分类号： C07C275/20 ,  G01K11/12 ,  G01D21/00

CPC分类号： G01K11/12 ,  C07C273/02 ,  C07C275/20 ,  C09B69/10 ,  G01K3/04 ,  G01N21/78 ,  G01N31/22 ,  G01N31/229

摘要： Crystallized diacetylenic compounds having certain crystallographic and other characteristics; diacetylenic compounds and mixtures crystallized from diacetylenic solutions; methods of preparing and identifying solvent systems for dissolving diacetylenic compounds; diacetylenic solutions; methods of recrystallizing diacetylenic compounds; crystals of 2,4-hexadiyn-1,6-bis(alkylurea) compounds; and ambient condition indicators and time-temperature condition indicators comprising crystallized diacetylenic compounds.

摘要翻译： 具有某些晶体学特性的结晶二炔化合物; 二乙炔化合物和从二乙炔溶液中结晶的混合物; 制备和鉴定溶解二乙炔化合物的溶剂体系的方法; 二乙酰溶液; 二乙炔化合物重结晶方法; 2,4-己二炔-1,6-双（烷基脲）化合物的晶体; 环境条件指标和包含结晶二乙炔化合物的时间 - 温度条件指标。

公开(公告)号：US20120175412A1

公开(公告)日：2012-07-12

申请号：US13276543

申请日：2011-10-19

申请人： Frederick R. GRABINER ,  Carl M. Lentz ,  Emily Moore ,  Thaddeus Prusik ,  Nicholas Puro ,  Bruce-Erik Osborn

发明人： Frederick R. GRABINER ,  Carl M. Lentz ,  Emily Moore ,  Thaddeus Prusik ,  Nicholas Puro ,  Bruce-Erik Osborn

IPC分类号： G06F17/30

CPC分类号： G16H20/00 ,  G06F19/00 ,  G06F19/321 ,  G06F19/3462 ,  G06F19/3475 ,  G06K9/4652 ,  G06K9/6215 ,  G06K2009/4666 ,  G06Q10/0833 ,  G06Q10/087 ,  G06Q30/0623 ,  G06T7/73 ,  G06T7/90 ,  G07G1/0054 ,  G07G1/0081 ,  G16H10/00 ,  G16H15/00 ,  G16H40/20 ,  G16H40/67

摘要： In part, the invention relates to computing systems and methods for electronically indicating the acceptability of a product. An image capture and communication device may analyze a product label that includes one or more monitors, authentication elements, and identification elements. The image capture and communication device may determine the type and features of the monitors, authentication elements, and identification elements. The image capture and communication device may transmit data based on the type and features to a host server, which may transmit data associated with the host product to the image capture and communication device in, inter alia, the form of an acceptability report.

摘要翻译： 部分地，本发明涉及用于电子地指示产品的可接受性的计算系统和方法。 图像捕获和通信设备可以分析包括一个或多个监视器，认证元件和识别元件的产品标签。 图像捕获和通信设备可以确定监视器，认证元件和识别元件的类型和特征。 图像捕获和通信设备可以基于类型和特征将数据发送到主机服务器，主机服务器可以特别地以可接受性报告的形式将与主机产品相关联的数据传送到图像捕获和通信设备。

公开(公告)号：US07517146B2

公开(公告)日：2009-04-14

申请号：US11844739

申请日：2007-08-24

申请人： Dawn E. Smith ,  Thaddeus Prusik ,  Omar Abbassi

发明人： Dawn E. Smith ,  Thaddeus Prusik ,  Omar Abbassi

IPC分类号： G01K1/00 ,  G01K11/00

CPC分类号： G01K11/06 ,  G01K3/04

摘要： An excess temperature indicator can provide a visual indication of past exposure of perishable, maturing and other host products to an elevated temperature exceeding a threshold temperature. The indicator can have an upper layer provided with a viewing window and a wick attached to the upper layer. A reservoir of heat-fusible indicator material can be disposed in contact with the wick, to fuse and move along the wick changing the visual appearance of a first portion of the wick viewable through the window, in response to an excess temperature event. Also, the indicator can have a region of fused upper layer material attaching the wick to the upper layer. Optionally, a window seal can extend around the viewing window to prevent migration of the indicator material. The indicator can be employed to monitor vaccines, foods and other products providing an enduring visual signal of exposure to potentially damaging temperature conditions.

摘要翻译： 过温度指示器可以提供易腐烂，成熟和其他主体产品过去暴露于超过阈值温度的高温的视觉指示。 指示器可以具有设置有观察窗口的上层和附接到上层的灯芯。 热熔指示剂材料的储存器可以布置成与芯接触，以便熔化并沿着芯移动，以响应于过高的温度事件而改变可通过窗口观察的芯的第一部分的视觉外观。 此外，指示器可以具有将芯连接到上层的熔融上层材料的区域。 可选地，窗口密封件可以围绕观察窗口延伸以防止指示剂材料的迁移。 该指标可用于监测疫苗，食品和其他产品，提供暴露于潜在有害温度条件的持久视觉信号。

公开(公告)号：US20080257251A1

公开(公告)日：2008-10-23

申请号：US12069025

申请日：2008-02-06

申请人： Dene H. Taylor ,  Thaddeus Prusik ,  Dawn Smith

发明人： Dene H. Taylor ,  Thaddeus Prusik ,  Dawn Smith

IPC分类号： G01K1/00

CPC分类号： G01K1/02 ,  G01K3/005 ,  G01K11/06 ,  G01K11/12 ,  G01K2207/04 ,  Y10S252/962

摘要： A freeze indicator employs, as active indicator element, dispersion of solid particles in a liquid medium which can be water or aqueous and which coagulates to provide an irreversible appearance change when subject to freezing. The liquid dispersion can be contained in an indicator volume around which extends a vapor block layer. The vapor block layer can prevent loss of liquid vapor from the dispersion and consequent drying out and dysfunctionality of the freeze indicator. For containing an aqueous medium, bilayer and trilayer laminate materials can be used which have a low water vapor transmission rate. The active indicator element can be a dilute colloidal dispersion of a metal such as gold or silver or other inorganic pigment material in water or an aqueous medium. Some embodiments avoid use of dispersants and the like and employ an active indicator element consisting of inorganic pigment particles, water and optionally an ice nucleating agent. Heavy water, or deuterated water can be components of the water, if desired.

摘要翻译： 冷冻指示器使用固体颗粒在液体介质中的分散体作为活性指示剂元素，该液体介质可以是水或水，并在凝固时提供不可逆的外观变化。 液体分散体可以包含在延伸蒸气阻挡层的指示体积中。 蒸气阻挡层可以防止液体蒸气从分散体中的损失，从而导致冷冻指示器的干燥和功能失调。 为了含有水性介质，可以使用具有低水蒸气透过率的双层和三层层压材料。 活性指示剂元素可以是诸如金或银之类的金属或其它无机颜料材料在水或水介质中的稀释胶体分散体。 一些实施方案避免使用分散剂等并且使用由无机颜料颗粒，水和任选的冰核成核剂组成的活性指示剂元件。 如果需要，重水或氘代水可以是水的组分。

公开(公告)号：US20050003551A1

公开(公告)日：2005-01-06

申请号：US10611302

申请日：2003-07-02

申请人： Thaddeus Prusik

发明人： Thaddeus Prusik

IPC分类号： G01N31/22

CPC分类号： G01N31/229

摘要： A product shelf life monitoring system comprising an active substituted diacetylenic monomer component indicator composition is responsive to an integral of varying temperature over time to effect a solid state polymerization in the active monomer which results in a visible change in color density or the like at a rate designed to closely approximate the degradation, or shelf life, of an associated foodstuff or medicament product. The reactivity of the monomer component upon which the time-temperature integral of the indicator composition, and thus the represented shelf life, primarily depends may be readily varied by refluxing a solution of the monomer in a selected solvent for a predetermined time prior to recrystallization of the monomer for incorporation into the indicator composition.

公开(公告)号：US5057434A

公开(公告)日：1991-10-15

申请号：US400308

申请日：1989-08-29

申请人： Thaddeus Prusik ,  Raymond M. Arnold

发明人： Thaddeus Prusik ,  Raymond M. Arnold

IPC分类号： B65D79/02 ,  G01K3/04 ,  G01N31/22

CPC分类号： G01K3/04 ,  B65D79/02 ,  G01N31/229 ,  B65D2203/00 ,  Y10S252/962

摘要： An accurate monitoring of the conditions of a perishable product is achieved by integrating two indicator types - a primary indicator which develops a color change as a result of cumulative time-temperature exposure and a threshold second indicator - into a single device. The combination of the two indicators in the same indicator device provides a human readible signal that gradually and irreversibly develops color as a function of time and temperature and more closely monitors the actual condition of a deteriorative product than does a single indicator. Important features of this integrated monitoring device are reliability and printability. The primary indicator in the system is assisted in color development by the secondary indictor that is set to trigger at a predetermined temperature. When this temperature is reached or exceeded both indicator mechanisms function in an additive mode to cause a break in the typical Arrhenius curve, which a primary indicator alone produces. This can be used to signal actual rather than an apparent the end of a product life. The secondary indicia can be formulated to change very rapidly as would be needed to detect the thawing of a frozen product or modified so as to act more slowly, i.e. over at time-temperature range, and may comprise a substance that melts or changes some physical property at a given temperature.

摘要翻译： 通过将两个指示器类型（一个主要指示器，将累积时间温度暴露的颜色变化和阈值第二个指示器）集成到一个设备中来实现对易腐烂产品的状况的准确监控。 相同指示器中的两个指示器的组合提供了人类可读信号，其随着时间和温度的变化逐渐且不可逆地发展出颜色，并且更密切地监视劣化产品的实际状况，而不是单个指示器。 该集成监控设备的重要特性是可靠性和可打印性。 系统中的主要指示器被辅助指示器辅助，其被设定为在预定温度下触发。 当达到或超过这个温度时，两个指示器机制都以加法模式起作用，导致典型的Arrhenius曲线中断，这是主要指标单独产生的。 这可以用来表示实际的，而不是明显的产品寿命的终结。 辅助标记可以配制成非常迅速地改变，如需要检测冷冻产品的解冻或被修饰的，以便更慢地起作用，即在时间 - 温度范围内，并且可以包括熔化或改变一些物理的物质 在给定温度下的性质。