公开(公告)号：US20100279301A1

公开(公告)日：2010-11-04

申请号：US12772429

申请日：2010-05-03

申请人： Arul Chinnaiyan ,  Rou Wang ,  David Morris ,  Scott Tomlins

发明人： Arul Chinnaiyan ,  Rou Wang ,  David Morris ,  Scott Tomlins

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2600/16

摘要： The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to genes and gene panels as diagnostic markers and clinical targets for bladder cancer. Methods, compositions, and kits for diagnosing, determining, and determining risk of tumor aggressiveness are disclosed.

摘要翻译： 本发明涉及用于癌症诊断，研究和治疗的组合物和方法，包括但不限于癌症标志物。 特别地，本发明涉及基因和基因片段作为膀胱癌的诊断标志物和临床靶标。 公开了用于诊断，确定和确定肿瘤侵袭性的风险的方法，组合物和试剂盒。

公开(公告)号：US08433087B2

公开(公告)日：2013-04-30

申请号：US12185902

申请日：2008-08-05

申请人： Morten Agerbaek Nordahn ,  David Morris

发明人： Morten Agerbaek Nordahn ,  David Morris

IPC分类号： H04R25/00

CPC分类号： H04R25/70 ,  H04R25/356 ,  H04R25/505 ,  H04R2225/43 ,  H04R2460/11 ,  H04R2460/15

摘要： A hearing aid (200) comprises at least one microphone (210), a signal processing means (220) and an output transducer (230). The signal processing means is adapted to receive an input signal from the microphone. The signal processing means is adapted to apply a hearing aid gain to the input signal to produce an output signal to be output by the output transducer, and the signal processing means further comprises means for adjusting the hearing aid gain up or down until the hearing aid gain differs from the direct transmission gain by more than a predetermined value.

摘要翻译： 助听器（200）包括至少一个麦克风（210），信号处理装置（220）和输出换能器（230）。 信号处理装置适于从麦克风接收输入信号。 所述信号处理装置适用于对所述输入信号施加助听器增益以产生由所述输出换能器输出的输出信号，并且所述信号处理装置还包括用于调节所述助听器增益的装置，直到所述助听器 增益不同于直接传输增益超过预定值。

公开(公告)号：US20130044559A1

公开(公告)日：2013-02-21

申请号：US13639342

申请日：2011-04-06

申请人： Robert Ashe ,  David Morris

发明人： Robert Ashe ,  David Morris

IPC分类号： B01F11/00 ,  B01F15/06

CPC分类号： B01F11/0077 ,  B01F13/005 ,  B01F13/0057 ,  B01F13/1013 ,  B01F13/1027 ,  B01J8/0403 ,  B01J19/006 ,  B01J19/0066 ,  B01J19/0093 ,  B01J19/1818 ,  B01J19/285 ,  B01J2208/00814 ,  B01J2208/028 ,  B01J2219/00063 ,  B01J2219/00094 ,  B01J2219/00135 ,  B01J2219/00189 ,  B01J2219/002 ,  B01J2219/00238

摘要： A continuous mixer/reactor and a mixing process are provided in which materials flow in an orderly fashion along the length of a channel (9) and the materials are mixed in a direction transverse to the axis of the channel (9) by the provision of agitator elements (5, 7) within the channel (9) and shaking the channel (9) so that the agitator elements (5, 7) move within the channel (9) in the radial direction of the channel (9).

摘要翻译： 提供连续的混合器/反应器和混合过程，其中材料沿着通道（9）的长度以有序的方式流动，并且材料通过提供通道（9）的横向于通道（9）的轴线的方向混合 在通道（9）内的搅拌器元件（5,7）和振动通道（9），使得搅拌器元件（5,7）在通道（9）的径向方向上在通道（9）内移动。

公开(公告)号：US20080292122A1

公开(公告)日：2008-11-27

申请号：US12185902

申请日：2008-08-05

申请人： Morten Agerbaek Nordahn ,  David Morris

发明人： Morten Agerbaek Nordahn ,  David Morris

IPC分类号： H04R25/00

CPC分类号： H04R25/70 ,  H04R25/356 ,  H04R25/505 ,  H04R2225/43 ,  H04R2460/11 ,  H04R2460/15

摘要： A hearing aid comprises at least one microphone, a signal processing means and an output transducer, the signal processing means being adaptive to receive an input signal from the microphone, wherein the signal processing means is adapted to apply a hearing aid gain to the input signal to produce an output signal to be output by the output transducer, and wherein the signal processing means further comprises means for adjusting the hearing aid gain if the hearing aid gain would be below a direct transmission gain calculated for the hearing aid.

摘要翻译： 助听器包括至少一个麦克风，信号处理装置和输出换能器，所述信号处理装置适于接收来自所述麦克风的输入信号，其中所述信号处理装置适于将助听器增益应用于所述输入信号 以产生要由输出换能器输出的输出信号，并且其中信号处理装置还包括用于在助听器增益低于为助听器计算的直接传输增益时调整助听器增益的装置。

公开(公告)号：US20070177858A1

公开(公告)日：2007-08-02

申请号：US11694379

申请日：2007-03-30

申请人： Ray Knoeppel ,  David Morris

发明人： Ray Knoeppel ,  David Morris

IPC分类号： F24H1/20

CPC分类号： F24H9/2021

摘要： A fluid-heating apparatus for heating a fluid and method of operating the same. The fluid-heating apparatus includes a heating element for heating a fluid surrounding the heating element and a control circuit connected to the heating element and connectable to a power source. The control circuit is configured to determine whether a potential dry-fire condition exists for the heating element. In one implementation, the method includes applying a first electric signal to the heating element, detecting a first value of an electrical characteristic during the application of the first electric signal, applying a second electric signal to the heating element, applying a third electric signal to the heating element, detecting a second value of the electrical characteristic during the application of the third electric signal; and determining whether a potential dry-fire condition exists based on the first and second values.

摘要翻译： 用于加热流体的流体加热装置及其操作方法。 流体加热装置包括用于加热围绕加热元件的流体的加热元件和连接到加热元件并可连接到电源的控制电路。 控制电路被配置为确定加热元件是否存在潜在的干火状态。 在一个实施方式中，该方法包括将第一电信号施加到加热元件，在施加第一电信号期间检测电特性的第一值，向加热元件施加第二电信号，将第三电信号施加到 所述加热元件在施加所述第三电信号期间检测所述电特性的第二值; 以及基于所述第一和第二值来确定是否存在潜在的干火条件。

公开(公告)号：US20070161003A1

公开(公告)日：2007-07-12

申请号：US10674575

申请日：2003-09-29

申请人： David Morris ,  Marc Malandro

发明人： David Morris ,  Marc Malandro

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12M3/00

CPC分类号： C12Q1/6886 ,  C12Q2565/501 ,  C12Q2600/136 ,  C12Q2600/158

摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

公开(公告)号：US20070154152A1

公开(公告)日：2007-07-05

申请号：US11702737

申请日：2007-02-06

申请人： David Morris

发明人： David Morris

IPC分类号： G02B6/44

CPC分类号： H02G9/06 ,  G02B6/4459 ,  G02B6/508 ,  H02G3/0481 ,  H02G9/065

摘要： A flexible innerduct structure is configured to contain a cable within a conduit. The innerduct structure includes a pair of adjacent strip-shaped layers of flexible material that are joined along their longitudinal edges to define a channel through which the cable can extend longitudinally through the innerduct structure between the layers. The adjacent layers have differing widths between their longitudinal edges, whereby the wider layer bulges away from the narrower layer to impart an open configuration to the channel. Other features of the innerduct structure relate to the material of which it is formed. Such features includes the structure of the material, such as a woven structure, and further include properties such as melting point, tensile strength, elongation, coefficient of friction, crimp resistance and compression recovery.

公开(公告)号：US20070076289A1

公开(公告)日：2007-04-05

申请号：US11528714

申请日：2006-09-26

申请人： Xiaojia Wang ,  David Morris ,  Fei Wang ,  Andrew Ho

发明人： Xiaojia Wang ,  David Morris ,  Fei Wang ,  Andrew Ho

IPC分类号： G02B26/00

CPC分类号： G02F1/167 ,  G02F2001/1676

摘要： The present invention relates to electrophoretic displays and methods of addressing such displays. The displays and methods are especially suitable for large size electronic boards or signs.

摘要翻译： 本发明涉及电泳显示器和寻址这种显示器的方法。 显示器和方法特别适用于大尺寸电子板或标牌。

公开(公告)号：US20070042385A1

公开(公告)日：2007-02-22

申请号：US11064736

申请日：2005-02-23

申请人： David Morris ,  Marc Malandro ,  Albert Lai ,  Christin Tse ,  Ali Fattaey

发明人： David Morris ,  Marc Malandro ,  Albert Lai ,  Christin Tse ,  Ali Fattaey

IPC分类号： C12Q1/68 ,  G01N33/574 ,  C07H21/04 ,  C12N15/09 ,  C07K14/82 ,  C07K16/30

CPC分类号： C07K14/4748 ,  C12Q1/6886 ,  C12Q2600/136

摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.

摘要翻译： 本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了与癌症相关的CA多肽，其呈递针对癌症的新型治疗靶点。 本发明还提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。

公开(公告)号：US20060217707A1

公开(公告)日：2006-09-28

申请号：US11335295

申请日：2006-01-18

申请人： Steven Daniel ,  David Morris

发明人： Steven Daniel ,  David Morris

IPC分类号： A61B18/14

CPC分类号： A61B18/1477 ,  A61B18/1815 ,  A61B2018/0016 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2018/143

摘要： Energy delivery systems and methods are provided for use in biological tissue. The energy delivery system includes an energy source and an electrode array. The electrode array includes bipolar electrodes positioned so a first spacing between a pair of adjacent electrodes is different relative to a second spacing between at least one other pair of adjacent electrodes. The electrode array and the energy source are coupled and configured to generate uniform energy density in target tissue according to impedance of the target tissue.