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公开(公告)号：US20080039413A1
公开(公告)日：2008-02-14
申请号：US10692382
申请日：2003-10-22
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： A61K31/713 , A61P35/00 , C07H21/00 , C07K14/00 , C07K16/00 , C07K2/00 , C12N1/00 , C12N15/63 , C12N5/12 , C12Q1/02 , C12Q1/68 , C40B40/06 , C40B40/10 , G01N33/53
CPC分类号： G01N33/57484 , C12Q1/6886 , C12Q2600/136 , G01N2500/00
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译： 本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了存在于细胞表面上的与癌症相关的CA多肽，并提出了针对癌症的新型治疗靶点。 本发明还提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。
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公开(公告)号：US20060166213A1
公开(公告)日：2006-07-27
申请号：US10540898
申请日：2003-12-22
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
CPC分类号： C07K14/4748 , A61K38/00 , C07K14/47
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer and provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译： 本发明涉及用于癌症的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了与癌症相关的CA多肽，并提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。
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公开(公告)号：US20050090434A1
公开(公告)日：2005-04-28
申请号：US10461862
申请日：2003-06-13
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： C07K14/47 , C12Q1/68 , G01N33/574 , A61K38/17 , C07H21/04
CPC分类号： C07K14/4748 , C12Q1/6886 , C12Q2600/136 , G01N33/57426 , G01N33/57492 , Y10T436/25
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
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公开(公告)号：US20070161003A1
公开(公告)日：2007-07-12
申请号：US10674575
申请日：2003-09-29
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
CPC分类号： C12Q1/6886 , C12Q2565/501 , C12Q2600/136 , C12Q2600/158
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
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公开(公告)号：US20070042385A1
公开(公告)日：2007-02-22
申请号：US11064736
申请日：2005-02-23
申请人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
发明人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
CPC分类号： C07K14/4748 , C12Q1/6886 , C12Q2600/136
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译： 本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了与癌症相关的CA多肽，其呈递针对癌症的新型治疗靶点。 本发明还提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。
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公开(公告)号：US20070218071A1
公开(公告)日：2007-09-20
申请号：US10663431
申请日：2003-09-15
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： A61K38/17 , A61K39/395 , C07K16/32 , C12N15/00 , C12N5/00 , C12P21/08 , C12Q1/68 , G01N33/574
CPC分类号： G01N33/5011 , A61K2039/505 , C07K14/4748 , G01N33/57426
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译： 本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了存在于细胞表面上的与癌症相关的CA多肽，并提出了针对癌症的新型治疗靶点。 本发明还提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽具有特异性的单克隆和多克隆抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。
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公开(公告)号：US20060228710A1
公开(公告)日：2006-10-12
申请号：US10545777
申请日：2004-02-17
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
CPC分类号： G01N33/57492 , A61K39/00 , C07K14/4748 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/57426
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polygonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
摘要翻译： 本发明涉及用于癌症尤其是淋巴瘤的检测，诊断和治疗的新型序列。 本发明提供癌症相关（CA）多核苷酸序列，其表达与癌症相关。 本发明提供了存在于细胞表面上的与癌症相关的CA多肽，并提出了针对癌症的新型治疗靶点。 本发明还提供了用于检测癌症的诊断组合物和方法。 本发明提供对CA多肽特异性的单克隆和多边形抗体。 本发明还提供用于癌症的筛选，预防和治疗的诊断工具和治疗组合物和方法。
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公开(公告)号：US20060194265A1
公开(公告)日：2006-08-31
申请号：US10669920
申请日：2003-09-23
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： G01N33/574 , C07H21/04 , C12P21/06 , A61K39/395 , C07K14/82 , C07K16/30
CPC分类号： C07K16/30 , A61K39/00 , C07K14/4748 , C07K14/82 , C12Q1/6886 , C12Q2565/501 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N33/574 , G01N33/57426 , G01N33/57492
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
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公开(公告)号：US20060024677A1
公开(公告)日：2006-02-02
申请号：US10895974
申请日：2004-07-20
申请人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
发明人： David Morris , Marc Malandro , Albert Lai , Christin Tse , Ali Fattaey
CPC分类号： G01N33/574 , C07K14/4748 , C07K16/30 , C12Q1/6837 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N2500/10
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
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公开(公告)号：US20070212351A1
公开(公告)日：2007-09-13
申请号：US11257477
申请日：2005-10-24
申请人： David Morris , Marc Malandro
发明人： David Morris , Marc Malandro
IPC分类号： A61K31/70 , A61K38/02 , A61K39/395 , C12Q1/68
CPC分类号： C07K14/4748 , A61K39/00 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/16 , G01N33/57426 , G01N33/57492
摘要： The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
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