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公开(公告)号：US08876754B2
公开(公告)日：2014-11-04
申请号：US11469054
申请日：2006-08-31
CPC分类号： A61M25/007 , A61F2/013
摘要： A delivery apparatus useful for infusing a therapeutic agent into a body lumen, the apparatus including a lumenal body defining at least one infusion port for infusing the therapeutic agent into the body lumen, and a sensing element which is distal of the at least one infusion port and adapted to sense the amount of infused therapeutic agent or any compound derived therefrom in the body lumen. Another embodiment of the apparatus includes a lumenal body defining at least one infusion port for infusing the therapeutic agent into the body lumen, and a filtration element which is distal of the at least one infusion port and adapted to deliver a reaction agent which may react with the therapeutic agent in the body lumen. A sensing element may be provided distal of the filtration element for sensing the amount of infused therapeutic agent or compounds derived therefrom in the body lumen.
摘要翻译： 一种用于将治疗剂注入体腔中的输送装置，所述装置包括限定用于将治疗剂注入体腔的至少一个输注端口的腔体，以及位于至少一个输注端口的远端的感测元件 并且适于感测输注的治疗剂或其体内衍生的任何化合物的量。 该装置的另一实施例包括限定用于将治疗剂注入体腔的至少一个输注端口的腔体，以及位于该至少一个输注端口的远端的适于输送可与 治疗剂在体腔内。 感测元件可以设置在过滤元件的远侧，用于感测在体腔中输注的治疗剂或其衍生的化合物的量。
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公开(公告)号：US20080097339A1
公开(公告)日：2008-04-24
申请号：US11469054
申请日：2006-08-31
CPC分类号： A61M25/007 , A61F2/013
摘要： In one form, the therapeutic agent delivery apparatus is used for infusing a therapeutic agent into a body lumen and includes a lumenal body defining a plurality of infusion ports for infusing the therapeutic agent into the body lumen, and a sensing element distal of the infusion ports and adapted to sense the amount of infused therapeutic agent or any compound derived from the therapeutic agent in the body lumen. In another form, the apparatus includes a lumenal body defining a plurality of infusion ports for infusing the therapeutic agent into the body lumen, and a filtration element distal of the infusion ports and adapted to deliver a reaction agent adapted to react with the therapeutic agent in the body lumen. A sensing element may be provided distal of the filtration element for sensing the amount of infused therapeutic agent or compounds derived therefrom in the body lumen.
摘要翻译： 在一种形式中，治疗剂递送装置用于将治疗剂注入体腔，并且包括界定多个用于将治疗剂注入体腔的输注端口的腔体，以及位于输液端口远端的感测元件 并且适于感测输注的治疗剂或源自体腔内的治疗剂的任何化合物的量。 在另一种形式中，该装置包括限定用于将治疗剂注入体腔内的多个输注端口的腔体，以及位于输注端口远端的过滤元件，并适于递送适于与治疗剂反应的反应剂 体腔。 感测元件可以设置在过滤元件的远侧，用于感测在体腔中输注的治疗剂或其衍生的化合物的量。
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公开(公告)号：US20080058758A1
公开(公告)日：2008-03-06
申请号：US11842999
申请日：2007-08-22
IPC分类号： A61M31/00
CPC分类号： A61M25/007 , A61F2/013
摘要： In one form, the therapeutic agent delivery apparatus is used for infusing a therapeutic agent into a body lumen and includes a lumenal body defining a plurality of infusion ports for infusing the therapeutic agent into the body lumen, and a sensing element distal of the infusion ports and adapted to sense the amount of infused therapeutic agent or any compound derived from the therapeutic agent in the body lumen. In another form, the apparatus includes a lumenal body defining a plurality of infusion ports for infusing the therapeutic agent into the body lumen, and a filtration element distal of the infusion ports and adapted to deliver a reaction agent adapted to react with the therapeutic agent in the body lumen. A sensing element may be provided distal of the filtration element for sensing the amount of infused therapeutic agent or compounds derived therefrom in the body lumen.
摘要翻译： 在一种形式中，治疗剂递送装置用于将治疗剂注入体腔，并且包括界定多个用于将治疗剂注入体腔的输注端口的腔体，以及位于输液端口远端的感测元件 并且适于感测输注的治疗剂或源自体腔内的治疗剂的任何化合物的量。 在另一种形式中，该装置包括限定用于将治疗剂注入体腔内的多个输注端口的腔体，以及位于输注端口远端的过滤元件，并适于递送适于与治疗剂反应的反应剂 体腔。 感测元件可以设置在过滤元件的远侧，用于感测在体腔中输注的治疗剂或其衍生的化合物的量。
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公开(公告)号：US20080146913A1
公开(公告)日：2008-06-19
申请号：US11612195
申请日：2006-12-18
IPC分类号： A61B5/15
摘要： A device for locating a venous structure of a patient includes a frame having a bottom surface and a top surface, an adhesive disposed on the bottom surface of the frame to allow the frame to be removably attached to skin or a patient, and one or more sections removably attached to the top surface of the frame. The sections are formed of a liquid crystal material that is sensitive to human skin temperature ranges.
摘要翻译： 用于定位患者的静脉结构的装置包括具有底表面和顶表面的框架，设置在框架的底表面上以允许框架可拆卸地附接到皮肤或患者的粘合剂，以及一个或多个 部分可移除地附接到框架的顶表面。 这些部分由对人体皮肤温度范围敏感的液晶材料形成。
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5.发明授权公开(公告)号：US09326742B2
公开(公告)日：2016-05-03
申请号：US12595165
申请日：2007-12-28
申请人： Alan D. Hirschman , Arthur E. Uber, III , David M. Reilly , John Kalafut , Frederick W. Trombley, III , Steven J. Remis , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths , Marc A. Mabie , Mark Trocki
发明人： Alan D. Hirschman , Arthur E. Uber, III , David M. Reilly , John Kalafut , Frederick W. Trombley, III , Steven J. Remis , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths , Marc A. Mabie , Mark Trocki
IPC分类号： A61M3/00 , A61B6/00 , A61B6/03 , A61B6/04 , A61M5/172 , G06F19/00 , G21G4/08 , A61B6/10 , A61B5/0205 , A61B5/00 , A61M5/00 , A61M5/145 , A61M5/168 , A61M5/178
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/00 , G06F19/3468 , G16H20/17 , G21F5/015 , G21G4/08
摘要： A hazardous fluid handling system which includes a housing having a radiation shielded internal chamber disposed therein which may accommodate a container holding a radioactive fluid, one or more radioactivity detectors positioned within the shielded internal chamber in operational proximity to the radioactive fluid in the container, and a dosimeter control device electronically coupled to the radioactivity detector(s) is disclosed. The dosimeter control device is operational for determining information regarding the radioactive fluid in the container based on individual measurements received from the one or more radioactivity detectors. The hazardous fluid handling system may be integrated into a patient support platform which includes a patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with the patient, and an integrated system controller.
摘要翻译： 一种危险的流体处理系统，其包括具有设置在其中的辐射屏蔽内部室的壳体，其可以容纳容纳放射性流体的容器，位于屏蔽内部室内的一个或多个放射性检测器，其操作接近容器中的放射性流体;以及 公开了一种电子耦合到放射性检测器的剂量计控制装置。 剂量计控制装置可操作用于基于从一个或多个放射性检测器接收的各个测量值来确定关于容器中的放射性流体的信息。 有害流体处理系统可以集成到患者支撑平台中，该患者支撑平台包括患者刺激装置，靠近患者支撑平台的成像器，用于将放射性药物流体输入患者的放射性药物流体输送系统， 病人和一个集成的系统控制器。
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6.发明授权Fluid delivery systems, devices and methods for delivery of hazardous fluids 有权用于输送危险液体的流体输送系统，装置和方法公开(公告)号：US09005166B2
公开(公告)日：2015-04-14
申请号：US13898680
申请日：2013-05-21
申请人： Arthur E. Uber, III , Alan D. Hirschman , David M. Griffiths , Frederick W. Trombley, III , David M. Reilly
发明人： Arthur E. Uber, III , Alan D. Hirschman , David M. Griffiths , Frederick W. Trombley, III , David M. Reilly
CPC分类号： A61M25/0045 , A61J1/2096 , A61M5/007 , A61M5/1408 , A61M5/142 , A61M5/1452 , A61M5/44 , A61M2202/049 , A61N5/1001
摘要： A system for delivering fluid to a patient includes a hazardous material enclosure suitable for holding a first container comprising a first fluid, and a pump device capable of pumping the first fluid from the first container and a second fluid from a second container. The hazardous materials enclosure has a cap which includes a flexible sealing member that cooperates with the first container to create a biohazard seal during connection of the first container to the cap. The system further includes a mixing device associated with the pump for mixing the first and second fluids for delivering the fluid mixture to the patient.
摘要翻译： 用于将流体输送到患者的系统包括适于保持包括第一流体的第一容器的危险材料外壳和能够从第一容器泵送第一流体的泵装置和来自第二容器的第二流体的泵装置。 危险材料外壳具有盖，该盖包括与第一容器配合的柔性密封构件，以在第一容器与盖连接期间产生生物危害密封。 该系统还包括与泵相关联的混合装置，用于混合第一和第二流体以将流体混合物输送给患者。
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公开(公告)号：US08192397B2
公开(公告)日：2012-06-05
申请号：US11425497
申请日：2006-06-21
申请人： David M. Griffiths , Rosemary Almon-Martin , Alan D. Hirschman , David M. Reilly , Frederick W. Trombley, III , Arthur E. Uber, III , William Jaecklein
发明人： David M. Griffiths , Rosemary Almon-Martin , Alan D. Hirschman , David M. Reilly , Frederick W. Trombley, III , Arthur E. Uber, III , William Jaecklein
IPC分类号： A61M29/00
CPC分类号： A61M25/10184 , A61M5/007 , A61M5/14566 , A61M5/16827 , A61M5/16854 , A61M25/007 , A61M25/104 , A61M2025/102 , A61M2025/1022
摘要： A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.
摘要翻译： 公开了组合的流体注入和充气系统，并且包括包括至少一个加压装置，流体路径和控制单元的流体输送系统。 流体路径适于经由包括球囊并且插入患者体内的导管将加压装置连接到患者。 控制单元可操作以控制流体输送系统。 在操作中，控制单元选择性地致动流体输送系统以流体注射模式或气球充气模式操作。 在流体注射模式中，加压装置将流体输送到流体路径用于流体注射程序。 在球囊膨胀模式中，加压装置将流体输送到流体路径，用于使与导管相关联的球囊膨胀。 操作员控制可以连接到控制单元以控制流体输送系统，并且可以是手持装置。
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8.发明申请公开(公告)号：US20110178359A1
公开(公告)日：2011-07-21
申请号：US12595165
申请日：2007-12-28
申请人： Alan D. Hirschman , Arthur E. Uber, III , Kevin P. Cowan , David M. Reilly , Edward J. Rhinehart , John Kalafut , Bronwyn Uber , Frederick W. Trombley, III , Steven J. Remis , Paul D. Levin , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths
发明人： Alan D. Hirschman , Arthur E. Uber, III , Kevin P. Cowan , David M. Reilly , Edward J. Rhinehart , John Kalafut , Bronwyn Uber , Frederick W. Trombley, III , Steven J. Remis , Paul D. Levin , Scott Griffith , Douglas Descalzi , Richard Dewit , David M. Griffiths
IPC分类号： A61M36/06
CPC分类号： A61N5/1001 , A61B5/0205 , A61B5/055 , A61B5/7289 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/107 , A61B6/4057 , A61B6/4258 , A61B6/4423 , A61B6/507 , A61B6/508 , A61B6/5288 , A61B6/548 , A61M5/007 , A61M5/14546 , A61M5/1456 , A61M5/16827 , A61M5/16881 , A61M5/1723 , A61M5/1785 , A61M2205/3576 , A61N5/1071 , A61N2005/1021 , A61N2005/1094 , G06F19/00 , G06F19/3468 , G16H20/17 , G21F5/015 , G21G4/08
摘要： An integrated radiopharmaceutical patient treatment system is disclosed including a patient support platform with an associated patient stimulus apparatus, an imager proximate the patient support platform, a radiopharmaceutical fluid delivery system for infusing a radiopharmaceutical fluid into a patient, a patient monitor to be associated with a patient, and an integrated system controller operably associated with the patient stimulus apparatus, imager, radiopharmaceutical fluid delivery system, and patient monitor to control and coordinate their operations. Within the patient treatment system the radiopharmaceutical fluid delivery system may be included comprising a radionuclide supply module, a radiopharmaceutical processing module, a quality control module, a patient injection module, and a controller. A hazardous fluid handling system including a docking station and a hazardous fluid transport device adapted to detachably dock with the docking station is further disclosed.
摘要翻译： 公开了一种集成的放射性药物患者治疗系统，其包括具有相关联的患者刺激装置的患者支撑平台，靠近患者支撑平台的成像器，用于将放射性药物流体输入患者的放射性药物流体输送系统，与 患者以及与患者刺激装置，成像器，放射性药物流体输送系统和患者监护器可操作地相关联以控制和协调其操作的集成系统控制器。 在患者治疗系统内，可以包括放射性药物流体递送系统，包括放射性核素供应模块，放射性药物处理模块，质量控制模块，患者注射模块和控制器。 进一步公开了一种危险的流体处理系统，其包括对接站和适于与对接站可拆卸地对接的危险流体输送装置。
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公开(公告)号：US07672710B2
公开(公告)日：2010-03-02
申请号：US11196806
申请日：2005-08-02
申请人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Karen Zelenski
发明人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Karen Zelenski
CPC分类号： A61B8/481 , A61B6/481 , A61B6/504 , A61B8/06 , A61M5/007 , A61M5/14546 , A61M5/1723 , A61M2205/581 , A61M2205/80 , G06F19/00 , G06F19/321 , G06F19/3468
摘要： A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.
摘要翻译： 用于产生患者的对比度增强的医学图像的系统包括对比度或增强介质的源，与对比度或增强介质源流体连接的加压单元，可操作以将能量施加到所述对比度或增强介质的区域的能量源 患者，成像单元，其基于由施加到患者的区域的能量产生的信号以及控制单元提供患者的内部视图的视觉显示。 在一个实施例中，该信号受到患者中的对比度或增强介质的状况的影响。 为了控制程序，控制单元基于该信号来调整患者的对比度或增强介质的状况。 通信接口优选地实现注射器子系统和成像子系统之间的信息。
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公开(公告)号：US06970735B2
公开(公告)日：2005-11-29
申请号：US10134858
申请日：2002-04-29
申请人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Vera Pagano , Karen Zelenski
发明人： Arthur E. Uber, III , Edward J. Rhinehart , Rosemary Almon-Martin , David M. Griffiths , Alan D. Hirschman , Francis J. Sciulli , Walter Grumski , Vera Pagano , Karen Zelenski
CPC分类号： A61B8/481 , A61B6/481 , A61B6/504 , A61B8/06 , A61M5/007 , A61M5/14546 , A61M5/1723 , A61M2205/581 , A61M2205/80 , G06F19/00 , G06F19/321 , G06F19/3468
摘要： A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.
摘要翻译： 用于产生患者的对比度增强的医学图像的系统包括对比度或增强介质的源，与对比度或增强介质源流体连接的加压单元，可操作以将能量施加到所述对比度或增强介质的区域的能量源 患者，成像单元，其基于由施加到患者的区域的能量产生的信号以及控制单元提供患者的内部视图的视觉显示。 在一个实施例中，该信号受到患者中的对比度或增强介质的状况的影响。 为了控制程序，控制单元基于该信号来调整患者的对比度或增强介质的状况。 通信接口优选地实现喷射器子系统和成像子系统之间的信息。
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