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公开(公告)号:US6149574A
公开(公告)日:2000-11-21
申请号:US40172
申请日:1998-03-17
CPC分类号: A61N5/1002 , A61N2005/1004
摘要: Disclosed is a dual catheter radiation delivery system, for delivering a dose of radiation to a treatment site, typically in a body lumen. The system comprises an outer sheath catheter, having an inflatable balloon thereon. The system further comprises an inner radiation delivery catheter, having a radially expandable structure such as a balloon with a radiation source thereon. The sheath catheter is positioned such that the sheath balloon is at the treatment site, and the radiation delivery catheter is transluminally advanced through the sheath catheter such that the radiation source is positioned within the sheath balloon. The radiation delivery balloon is inflated within the sheath balloon, to position the radioactive source near the vessel wall. The source may comprise a thin film carried by the radiation delivery balloon, having a radioactive isotope implanted therein or chemically bonded thereto. Alternatively, the radioactive isotope may be implanted within or adhered to the radiation delivery balloon.
摘要翻译: 公开了一种双导管辐射递送系统,用于将一定剂量的辐射递送到通常在体腔内的治疗部位。 该系统包括在其上具有可膨胀气囊的外护套导管。 该系统还包括内辐射递送导管,其具有径向可扩张的结构,例如其上具有辐射源的球囊。 护套导管被定位成使得护套球囊处于治疗部位,并且辐射输送导管通过鞘导管被平滑地推进,使得辐射源位于护套球囊内。 辐射递送球囊在鞘球囊内充气,以将放射源放置在血管壁附近。 源可以包括由辐射递送球囊携带的薄膜,其具有植入其中或化学键合的放射性同位素。 或者,放射性同位素可以植入辐射递送气球内或附着于辐射递送气球。
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公开(公告)号:US20050005823A1
公开(公告)日:2005-01-13
申请号:US10852663
申请日:2004-05-25
IPC分类号: C04B20/00 , C04B14/28 , C04B18/08 , C04B20/10 , C04B22/00 , C04B24/00 , C04B28/02 , C04B40/00
CPC分类号: C04B20/10 , C04B40/0028 , C04B40/0042 , Y02W30/92 , C04B20/026 , C04B28/02 , C04B2103/00 , C04B18/08 , C04B2103/0088
摘要: The invention relates to a particular additive and method for dispersing an admixture in a cementitious composition comprising a hydraulic cement, to provide activation of the admixture on mixing of the cementitious composition with water wherein the particles of the particulate additive comprise a carrier comprising pozzolanic material and an admixture bound to the particulate carrier wherein the particles of the additive have a median particle size of between one tenth and one half of the median particle size of the cement used in the cementitious composition.
摘要翻译: 本发明涉及一种用于将混合物分散在包含水硬性水泥的水泥组合物中的特定添加剂和方法,以在水泥组合物与水混合时提供混合物的活化,其中颗粒添加剂的颗粒包括包含火山灰材料的载体, 与颗粒载体结合的混合物,其中添加剂的颗粒的中值粒度为水泥组合物中使用的水泥的中值粒径的十分之一和一半。
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公开(公告)号:US5788262A
公开(公告)日:1998-08-04
申请号:US574881
申请日:1995-12-19
申请人: Michael A. Dazy , Paul McCormick , Mark F. Jacoby
发明人: Michael A. Dazy , Paul McCormick , Mark F. Jacoby
CPC分类号: B60G15/067 , B60G15/063 , B60G2200/46 , B60G2202/12 , B60G2202/143 , B60G2204/124 , B60G2204/1242 , B60G2204/128 , B60G2204/43 , B60G2204/44 , B60G2204/61
摘要: An automotive suspension strut module has an upper mount assembly which includes a unitary plastic upper mount carrier formed with a through passage which is concentrically disposed about the strut principal axis. The passage is formed with a recessed pocket terminating in an internal annular shoulder, on which is seated a composite strut rod isolator having a metal rod connector cup embedded therein. The rod threaded upper end, which is positioned through a cup bottom wall aperture for threaded attachment by a nut, has its isolator annulus bonded to the connector cup by virtue of the side wall of the connector cup being embedded in the annulus of the rod isolator, whereby the strut rod loads may be tuned independently of the suspension travel loads. An upper end of the plastic carrier is molded with a radially outward flange, defining a circular undersurface seat for an upper end of the suspension helical spring, thereby providing a compact light weight strut upper mount assembly that is readily mounted to the vehicle body structure.
摘要翻译: 汽车悬架支柱模块具有上部安装组件,其包括形成有贯穿通道的整体式塑料上部安装架,该贯通通道围绕支柱主轴同心地设置。 该通道形成有终止于内部环形肩部中的凹进的凹口,在其上放置有嵌入其中的金属棒连接器杯的复合支柱隔离器。 杆螺纹上端通过杯底壁孔定位,用螺母螺纹连接,由于连接器杯的侧壁嵌入在杆隔离器的环形空间中,其隔离件环连接到连接杯上 ,由此可以独立于悬架行程负载来调节支杆负载。 该塑料载体的上端模制有径向向外的凸缘,其限定了用于悬挂螺旋弹簧的上端的圆形下表面座,从而提供了一种紧凑的轻型支柱上安装组件,其易于安装到车体结构。
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公开(公告)号:US20100310871A1
公开(公告)日:2010-12-09
申请号:US12833168
申请日:2010-07-09
申请人: Paul McCormick , Geoffrey Trotter
发明人: Paul McCormick , Geoffrey Trotter
CPC分类号: C01G9/02 , A61K8/27 , A61K2800/262 , A61Q17/04 , C01P2004/03 , C01P2004/45 , C01P2004/51 , C01P2006/12 , C01P2006/14 , C01P2006/17 , C01P2006/60 , Y10T428/2982
摘要: A zinc oxide powder is described, which, when used in a dispersion at a concentration of at least 50 wt % of zinc oxide, produces a transparent composition having a total visible transmittance through a path length of 20 microns at 550 nm of at least one of; at least 70%, at least 75%, at least 80% or at least 85%. The powder has a number average zinc oxide aggregate size of at least 0.8 microns, at least 1 micron, at least 2 microns or at least 3 microns. Use of the zinc oxide powder reduces the risk of transdermal penetration.
摘要翻译: 描述了一种氧化锌粉末,当其以至少50重量%浓度的氧化锌的分散体中使用时,产生透明组合物,该透明组合物在550nm处的路径长度为20微米,至少一个 的; 至少70%,至少75%,至少80%或至少85%。 粉末的数均氧化锌聚集体尺寸为至少0.8微米,至少1微米,至少2微米或至少3微米。 氧化锌粉末的使用降低透皮渗透的风险。
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公开(公告)号:US20070078506A1
公开(公告)日:2007-04-05
申请号:US11580201
申请日:2006-10-12
申请人: Paul McCormick , Stefan Schreck
发明人: Paul McCormick , Stefan Schreck
IPC分类号: A61F2/06
CPC分类号: A61F2/966 , A61F2/07 , A61F2/90 , A61F2/954 , A61F2002/067 , A61F2002/072 , A61F2002/075 , A61F2002/077 , A61M25/0021 , A61M25/0032 , A61M25/0662
摘要: A method of treating an aneurysm comprising placing an aspiration catheter in communication with the aneurysm. A prosthesis is deployed across an opening to the aneurysm to isolate at least a portion of the aneurysm. Material is aspirated from the aneurysm. Embolizing or other material may be introduced into the aneurysm.
摘要翻译: 一种治疗动脉瘤的方法,包括将吸入导管与动脉瘤连通。 将假体部署在动脉瘤的开口处以隔离至少一部分动脉瘤。 材料从动脉瘤中吸出。 可将栓塞或其他材料引入动脉瘤。
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公开(公告)号:US20070096547A1
公开(公告)日:2007-05-03
申请号:US11260626
申请日:2005-10-27
申请人: Paul Gritt , Richard Burns , Paul McCormick , David Case , David Seifrit
发明人: Paul Gritt , Richard Burns , Paul McCormick , David Case , David Seifrit
IPC分类号: B60T17/00
CPC分类号: B60T17/22 , F16D65/00 , F16D2250/00 , F16D2250/0092
摘要: A method is provided for sizing a brake system for an automobile using a processor. The method comprises gathering characteristics of the automobile and then calculating a maximum rotor size based the characteristics. Next, a specific torque required to skid the automobile at a selected deceleration is calculated for the brake system at driver only weight, and then a final brake caliper is selected based on the specific torque requirement and maximum brake rotor size. Finally, the selected rotor and brake caliper is evaluated to determine if thermal dissipation requirements for city driving conditions are met.
摘要翻译: 提供了一种用于使用处理器来调整用于汽车的制动系统的尺寸的方法。 该方法包括收集汽车的特性,然后根据特征计算最大转子尺寸。 接下来,以仅以驾驶员重量计算制动系统所需的以所选择的减速度滑动汽车所需的特定扭矩,然后基于特定扭矩要求和最大制动转子尺寸来选择最终制动钳。 最后,对所选择的转子和制动钳进行评估,以确定是否符合城市驾驶条件的散热要求。
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公开(公告)号:US20050245891A1
公开(公告)日:2005-11-03
申请号:US11104303
申请日:2005-04-12
申请人: Paul McCormick , Stefan Schreck
发明人: Paul McCormick , Stefan Schreck
CPC分类号: A61M25/0068 , A61B17/12022 , A61B17/12118 , A61B17/12186 , A61B17/1219 , A61B2017/1205 , A61B2217/005 , A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61M25/0023 , A61M25/0032 , A61M25/0069 , A61M25/008 , A61M25/0097 , A61M2025/0004 , A61M2025/0681
摘要: A method of treating an aneurysm comprising placing an aspiration catheter in communication with the aneurysm. A prosthesis is deployed across an opening to the aneurysm to isolate at least a portion of the aneurysm. Material is aspirated from the aneurysm. Embolizing or other material may be introduced into the aneurysm.
摘要翻译: 一种治疗动脉瘤的方法,包括将吸入导管与动脉瘤连通。 将假体部署在动脉瘤的开口处以隔离至少一部分动脉瘤。 材料从动脉瘤中吸出。 可将栓塞或其他材料引入动脉瘤。
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公开(公告)号:US20100316582A1
公开(公告)日:2010-12-16
申请号:US12833092
申请日:2010-07-09
CPC分类号: C01G9/02 , A61K8/27 , A61K2800/262 , A61Q17/04 , C01P2004/03 , C01P2004/45 , C01P2004/51 , C01P2006/12 , C01P2006/14 , C01P2006/17 , C01P2006/60 , Y10T428/2982
摘要: A broad-spectrum UV photoprotective composition is described. The composition is characterized in that the composition comprises mesoporous zinc oxide aggregates having an average aggregate size of at least 0.8 microns dispersed in a carrier and the composition is visibly transparent. Sufficient zinc oxide is included in the composition to achieve an SPF greater than 15, greater than 25, greater than 30, or greater than 50.
摘要翻译: 描述了广谱UV光保护组合物。 该组合物的特征在于,该组合物包含分散在载体中的平均聚集体尺寸至少为0.8微米的介孔氧化锌聚集体,并且该组合物是明显透明的。 组合物中包含足够的氧化锌以达到大于15,大于25,大于30或大于50的SPF。
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公开(公告)号:US20090028948A1
公开(公告)日:2009-01-29
申请号:US11813116
申请日:2005-12-30
申请人: Trevor Payne , Felix Meiser , Almar Postma , Raffaele Cammarano , James Williams , Paul McCormick , Aaron Dodd , Frank Caruso
发明人: Trevor Payne , Felix Meiser , Almar Postma , Raffaele Cammarano , James Williams , Paul McCormick , Aaron Dodd , Frank Caruso
IPC分类号: A61K9/14 , A61K31/519 , A61K31/551 , A61K31/192 , A61K31/196
CPC分类号: A61K9/5123 , A61K9/5192 , A61K31/192 , A61K31/196 , A61K31/4985 , A61K31/5513
摘要: The present invention relates to improved therapeutically active nanocomposite microstructure compositions, including nanoparticle compositions and nanoparticle preparations. Preferred embodiments include nanoparticle compositions comprising nanoparticles of a therapeutically active agent dispersed in a carrier matrix. The invention also relates to a method for preparing said compositions and preparations using solid-state mechanochemical synthesis. Further, it relates to therapeutic products produced using said compositions and to methods of treatment using the compositions.
摘要翻译: 本发明涉及改进的治疗活性纳米复合微结构组合物,包括纳米颗粒组合物和纳米颗粒制剂。 优选的实施方案包括纳米颗粒组合物,其包含分散在载体基质中的治疗活性剂的纳米颗粒。 本发明还涉及使用固态机械化学合成制备所述组合物和制剂的方法。 此外,它涉及使用所述组合物生产的治疗产品和使用该组合物的治疗方法。
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公开(公告)号:US20060153769A1
公开(公告)日:2006-07-13
申请号:US10541471
申请日:2004-01-06
申请人: John Robinson , Lara Heatley , Takuya Tsuzuki , David Lee , Paul McCormick
发明人: John Robinson , Lara Heatley , Takuya Tsuzuki , David Lee , Paul McCormick
IPC分类号: C01F7/02
CPC分类号: C01F7/30 , C01F7/02 , C01F7/442 , C01P2004/03 , C01P2004/20 , C01P2004/22 , C01P2004/51 , C01P2004/54 , C01P2004/61 , C01P2004/62 , C09C1/0018 , C09C1/407
摘要: A process for producing plate-like alumina particles with a high aspect ratio is described. Nano-sized particles of an aluminium precursor compound, optionally formed by milling, are mixed with a sufficient volume fraction of a diluent and heat treated to form substantially discrete plate-like alpha alumina particles dispersed in the diluent. A mineraliser may be added to lower the effective melting point of the system. Substantially discrete plate-like particles may be formed without agitation when the heat treatment is conducted below the melting point of the diluent.
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