公开(公告)号：US20130056366A1

公开(公告)日：2013-03-07

申请号：US13669729

申请日：2012-11-06

申请人： Brian B. Elson ,  Brian C. Large ,  Peter Norman

发明人： Brian B. Elson ,  Brian C. Large ,  Peter Norman

IPC分类号： C25B11/03 ,  C02F1/461 ,  C25B9/00

CPC分类号： C02F1/4691 ,  C02F1/283 ,  C02F1/46114 ,  C02F2001/46133 ,  C02F2001/46161 ,  C02F2201/46145 ,  C02F2209/02 ,  C02F2209/05 ,  C02F2209/06 ,  C02F2303/16

摘要： A method and system for treating a fluid includes an electrode with an outer housing having openings in a side wall thereof, a granular conductive material encapsulated within the outer housing, and an electrical terminal located at least partially within the outer housing and in electrical communication with the granular conductive material, wherein the openings are configured to permit ions in a fluid to be treated to pass there through so as to come into contact with the granular conductive material. The system includes a treatment tank and electrodes within the tank being charged to differing polarities by a voltage source. The method includes applying a first polarity to at least one electrode, oppositely charging one or more of other spaced apart electrodes, and flowing the fluid within the space so as to treat the fluid.

摘要翻译： 用于处理流体的方法和系统包括具有在其侧壁中具有开口的外壳体的电极，封装在外壳体内的颗粒状导电材料，以及至少部分地位于外壳体内并与外壳体电连通的电端子 所述颗粒状导电材料，其中所述开口被配置为允许要处理的流体中的离子通过所述流体以与所述粒状导电材料接触。 该系统包括处理槽，并且通过电压源将槽内的电极充电到不同的极性。 该方法包括对至少一个电极施加第一极性，相反地对一个或多个其它间隔开的电极充电，并使流体在空间内流动以便处理流体。

公开(公告)号：US20100059378A1

公开(公告)日：2010-03-11

申请号：US12554854

申请日：2009-09-04

申请人： Brian B. Elson ,  Brian C. Large ,  Peter Norman

发明人： Brian B. Elson ,  Brian C. Large ,  Peter Norman

IPC分类号： B01D61/42 ,  B01D61/46

CPC分类号： C02F1/4691 ,  C02F1/283 ,  C02F1/46114 ,  C02F2001/46133 ,  C02F2001/46161 ,  C02F2201/46145 ,  C02F2209/02 ,  C02F2209/05 ,  C02F2209/06 ,  C02F2303/16

摘要： A method and system for treating a fluid includes an electrode with an outer housing having openings in a side wall thereof, a granular conductive material encapsulated within the outer housing, and an electrical terminal located at least partially within the outer housing and in electrical communication with the granular conductive material, wherein the openings are configured to permit ions in a fluid to be treated to pass there through so as to come into contact with the granular conductive material. The system includes a treatment tank and electrodes within the tank being charged to differing polarities by a voltage source. The method includes applying a first polarity to at least one electrode, oppositely charging one or more of other spaced apart electrodes, and flowing the fluid within the space so as to treat the fluid.

摘要翻译： 用于处理流体的方法和系统包括具有在其侧壁中具有开口的外壳体的电极，封装在外壳体内的颗粒状导电材料，以及至少部分地位于外壳体内并与外壳体电连通的电端子 所述颗粒状导电材料，其中所述开口被配置为允许要处理的流体中的离子通过所述流体以与所述粒状导电材料接触。 该系统包括处理槽，并且通过电压源将槽内的电极充电到不同的极性。 该方法包括对至少一个电极施加第一极性，相反地对一个或多个其它间隔开的电极充电，并使流体在空间内流动以便处理流体。

公开(公告)号：US20090045074A1

公开(公告)日：2009-02-19

申请号：US12175624

申请日：2008-07-18

申请人： Richard L. Hoover ,  Brian B. Elson ,  Brian C. Large ,  Peter Norman

发明人： Richard L. Hoover ,  Brian B. Elson ,  Brian C. Large ,  Peter Norman

IPC分类号： B01J19/08 ,  C25B11/12 ,  C01B31/02

CPC分类号： C02F1/4691 ,  C02F1/283 ,  C02F1/46114 ,  C02F2001/46133 ,  C02F2001/46161 ,  C02F2201/46145 ,  C02F2209/02 ,  C02F2209/05 ,  C02F2209/06 ,  C02F2303/16

摘要： An electrode for use in a deionization apparatus includes a conductive material that is in a granular form and is arranged in a layer that is defined by a first face and a second face. The electrode includes a substrate that is disposed against the first face, and a first member that is disposed against the second face and is formed to permit a fluid to pass through the first member and into contact with the granular conductive material to permit absorption of ions by the granular conductive material.

摘要翻译： 用于去离子装置的电极包括粒状形式的导电材料，并且被布置在由第一面和第二面限定的层中。 所述电极包括抵靠所述第一面设置的基板和抵靠所述第二面设置的第一部件，所述第一部件形成为允许流体通过所述第一部件并与所述粒状导电材料接触以允许吸收离子 通过颗粒状导电材料。

公开(公告)号：US07754086B2

公开(公告)日：2010-07-13

申请号：US10591776

申请日：2005-02-28

申请人： Tony Whittaker ,  Peter Norman ,  Darryl Smith

发明人： Tony Whittaker ,  Peter Norman ,  Darryl Smith

IPC分类号： C02F11/14

CPC分类号： C02F11/14 ,  B01D21/0012 ,  B01D21/01 ,  B01D21/2461 ,  B01D21/26 ,  B01D21/262 ,  C02F1/56 ,  C02F2103/10 ,  C02F2103/28 ,  C02F2103/30

摘要： A process of dewatering an aqueous suspension comprising dosing the suspension with a flocculating amount of a first flocculant to form a thickened suspension and mixing into the thickened suspension a dewatering amount of a second flocculant and subjecting the thickened suspension to mechanical dewatering to form a cake, characterised in that the second flocculant comprises a water-soluble or water swellable polymer that is mixed into the suspension in the form of (i) substantially dry polymer particles or (ii) an aqueous composition comprising dissolved or hydrated polymer having a polymer concentration of at least 2% by weight and having a intrinsic viscosity of at least 3 dl/g.

摘要翻译： 一种将水性悬浮液脱水的方法，包括用絮凝量的第一絮凝剂给悬浮液加料以形成增稠的悬浮液，并将脱水量的第二絮凝剂混合到增稠的悬浮液中，并使增稠的悬浮液进行机械脱水以形成滤饼， 其特征在于，所述第二絮凝剂包含水溶性或水可溶胀聚合物，所述聚合物以（i）基本上干燥的聚合物颗粒的形式混合到所述悬浮液中，或（ii）含有聚合物浓度为 至少2重量％，特性粘度至少为3dl / g。

公开(公告)号：US5264458A

公开(公告)日：1993-11-23

申请号：US913513

申请日：1992-07-14

申请人： Ulrich Niewohner ,  Franz-Peter Hoever ,  Elisabeth Perzborn ,  Volker-Bernd Fiedler ,  Peter Norman ,  Hilary P. Francis ,  Marie G. McKenniff

发明人： Ulrich Niewohner ,  Franz-Peter Hoever ,  Elisabeth Perzborn ,  Volker-Bernd Fiedler ,  Peter Norman ,  Hilary P. Francis ,  Marie G. McKenniff

IPC分类号： C07C237/06 ,  C07C311/17 ,  C07C311/29 ,  C07D311/92 ,  C07D311/94 ,  C07D493/04 ,  A61K31/24 ,  A61K31/18 ,  A61K31/19

CPC分类号： C07D493/04 ,  C07C237/06 ,  C07C311/17 ,  C07C311/29 ,  C07D311/92 ,  C07D311/94 ,  C07C2102/08 ,  C07C2102/10 ,  C07C2103/24 ,  C07C2103/26

摘要： Iso- and heterocyclic phenylsulphonamides can be prepared by reaction of corresponding iso- and heterocyclic amines with phenylsulphonic acid derivatives. The iso- and heterocyclic phenylsulphonamides have thrombocyte aggregation-inhibiting and thromboxane A.sub.2 antagonist action and can be used in medicaments.

摘要翻译： 异构和杂环苯基磺酰胺可以通过相应的异杂环胺和苯基磺酸衍生物的反应来制备。 异硫醚和杂环苯基磺酰胺具有血小板聚集抑制和血栓素A2拮抗作用，可用于药物。

公开(公告)号：US5039670A

公开(公告)日：1991-08-13

申请号：US599321

申请日：1990-10-17

申请人： Horst Boshagen ,  Ulrich Muller ,  Ulrich Rosentreter ,  Erwin Bischoff ,  Volker-Bernd Fiedler ,  Elisabeth Perzborn ,  Joachim Hutter ,  Peter Norman ,  Nigel J. Cuthbert ,  Hilary P. Francis ,  Marie G. McKenniff

发明人： Horst Boshagen ,  Ulrich Muller ,  Ulrich Rosentreter ,  Erwin Bischoff ,  Volker-Bernd Fiedler ,  Elisabeth Perzborn ,  Joachim Hutter ,  Peter Norman ,  Nigel J. Cuthbert ,  Hilary P. Francis ,  Marie G. McKenniff

IPC分类号： C07D209/86 ,  A61K31/40 ,  A61K31/403 ,  A61P7/02 ,  A61P9/08 ,  A61P9/10 ,  A61P11/00 ,  A61P37/08 ,  C07D209/88 ,  C07D209/94

CPC分类号： C07D209/88

摘要： Substituted antithrombotic substituted cycloalkano[b]-dihydroindole- and -indole-sulphonamides for treatment of thromboses, thromboembolisms, ischemias, asthma and allergies, of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are hydrogen or other radicals,X is aryl, alkyl or CF.sub.3,m and Z each is 1,2,3 or 4,n is 0, 1 or 2,A is a bond or --NH--, andY is OH, alkoxy, aryloxy, amino or sulphonylamine, with the proviso that, in all cases, two of the substituents R.sup.1 -R.sup.4 are other than hydrogen in the event that m represents the number 2 and Y represents the hydroxyl group,or a salt thereof.

摘要翻译： 用于治疗式（I）的血栓形成，血栓栓塞，缺血，哮喘和过敏的取代的抗血栓形成取代的环烷基[b] - 二氢吲哚和吲哚磺酰胺，其中R 1，R 2，R 3和R 4是氢或其它 基团，X是芳基，烷基或CF 3，m和Z各自为1,2,3或4，n为0,1或2，A为键或-NH-，Y为OH，烷氧基，芳氧基，氨基 或磺酰胺，条件是在所有情况下，在m表示数2且Y表示羟基的情况下，两个取代基R 1 -R 4不同于氢，或其盐。

公开(公告)号：US07754087B2

公开(公告)日：2010-07-13

申请号：US10591878

申请日：2005-02-28

申请人： Tony Whittaker ,  Peter Norman ,  Darryl Smith

发明人： Tony Whittaker ,  Peter Norman ,  Darryl Smith

IPC分类号： C02F11/14

CPC分类号： C02F1/56

摘要： A process of dewatering aqueous suspension employing a flocculating system comprising treating the suspension with a flocculating amount of a first flocculant and a dewatering amount of a second flocculant, and subjecting the suspension to mechanical dewatering to form a cake, wherein the first flocculant brings about flocculation and assists thickening of the suspension and the second flocculant is a water-soluble or water swellable polymer that is mixed into the suspension is a water-soluble or water swellable particulate polymer having a particle diameter of at least 20 microns.

摘要翻译： 一种使用絮凝系统脱水水性悬浮液的方法，包括用絮凝量的第一絮凝剂和脱水量的第二絮凝剂处理悬浮液，并对悬浮液进行机械脱水以形成滤饼，其中第一絮凝剂引起絮凝 并且有助于悬浮液的增稠，并且第二絮凝剂是混合到悬浮液中的水溶性或水可溶胀聚合物是具有至少20微米的粒径的水溶性或水可溶胀的颗粒状聚合物。

公开(公告)号：US5246966A

公开(公告)日：1993-09-21

申请号：US816162

申请日：1991-12-30

申请人： Heinrich Meier ,  John E. B. Ransohoff ,  Trevor S. Abram ,  Peter Norman ,  Tudhope Stephen R. ,  Phillip J. Gardiner ,  Nigel J. Cuthbert ,  Hilary P. Francis

发明人： Heinrich Meier ,  John E. B. Ransohoff ,  Trevor S. Abram ,  Peter Norman ,  Tudhope Stephen R. ,  Phillip J. Gardiner ,  Nigel J. Cuthbert ,  Hilary P. Francis

IPC分类号： C07C323/62 ,  A61K31/19 ,  A61K31/194 ,  A61K31/235 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  A61P11/06 ,  A61P13/12 ,  A61P29/00 ,  A61P37/08 ,  A61P43/00 ,  C07C20060101 ,  C07C69/734 ,  C07C319/20

CPC分类号： C07C69/734 ,  C07C323/62

摘要： The new substituted alkenoic acid derivatives can be prepared by reacting the appropriate aldehyde with a phosphonium compound. The compounds have leukotriene antagonistic properties and can be incorporated into pharmaceutical compositions.

公开(公告)号：US5221760A

公开(公告)日：1993-06-22

申请号：US891629

申请日：1992-06-01

申请人： Ulrich Rosentreter ,  Harold C. Kluender ,  Trevor S. Abram ,  Peter Norman ,  Steven R. Tudhope

发明人： Ulrich Rosentreter ,  Harold C. Kluender ,  Trevor S. Abram ,  Peter Norman ,  Steven R. Tudhope

IPC分类号： C07C43/225 ,  C07C43/23 ,  C07C63/14 ,  C07C65/24 ,  C07C309/73 ,  C07C323/56 ,  C07F7/18 ,  C07F9/54

CPC分类号： C07F9/5456 ,  C07C309/73 ,  C07C323/56 ,  C07C43/225 ,  C07C43/23 ,  C07C63/14 ,  C07C65/24 ,  C07F7/1852 ,  C07F9/5407

摘要： An alkenoic acid derivative of the formula ##STR1## in which X and Y are identical or different and represent sulfur, sulfoxide, sulfone, an alkylene chain, --SCH.sub.2 --, or oxygen or a direct bond,W represents --CH.dbd.CH-- or --CH.sub.2 --CH.sub.2 --,o represents a number 1 to 5,A and B are identical or different and represent carboxyl, carboxymethylene, tetrazolyl or tetrazolylmethylene, or --CO.sub.2 R.sup.9 or --CH.sub.2 CO.sub.2 R.sup.9 or --CONR.sup.10 R.sup.11 or nitrilen represents a number 1 to 10,m represents a number 0 to 7,T and Z are identical or different and represent oxygen or a direct bond andR.sup.2, R.sup.3, R.sup.8 are identical or different and represent hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, trifluoromethoxy, cyano or nitro andR.sup.9 is lower alkyl and R.sup.10 and R.sup.11 are hydrogen, lower alkyl, alkylsulfonyl or arylsulfonyl or together are an alkylene chain to form a ringand pharmaceutically acceptable salts thereof. Such alkenoic acid derivatives are useful as leucotriene disease antagonists.

摘要翻译： 其中X和Y相同或不同并表示硫，亚砜，砜，亚烷基链，-SCH 2 - 或氧或直接键的式（I）的链烯酸衍生物，W表示-CH = CH-或-CH 2 -CH 2 - ，o表示数1至5，A和B相同或不同，表示羧基，羧基亚甲基，四唑基或四唑基亚甲基，或-CO 2 R 9或-CH 2 CO 2 R 9或-CONR 10 R 11或腈n表示1 至10，m表示0至7的数，T和Z相同或不同，表示氧或直接键，R2，R3，R8相同或不同，表示氢，烷基，烷氧基，卤素，三氟甲基，三氟甲氧基，氰基 或硝基，R 9为低级烷基，R 10和R 11为氢，低级烷基，烷基磺酰基或芳基磺酰基，或一起为形成环的亚烷基链及其药学上可接受的盐。 这样的链烯酸衍生物可用作白三烯类疾病拮抗剂。

公开(公告)号：US5159097A

公开(公告)日：1992-10-27

申请号：US618184

申请日：1990-11-26

申请人： Ulrich Rosentreter ,  Harold C. Kluender ,  Trevor S. Abram ,  Peter Norman ,  Steven R. Tudhope

发明人： Ulrich Rosentreter ,  Harold C. Kluender ,  Trevor S. Abram ,  Peter Norman ,  Steven R. Tudhope

IPC分类号： A61K31/19 ,  A61K31/215 ,  A61K31/235 ,  A61K31/275 ,  A61K31/41 ,  A61P11/08 ,  A61P43/00 ,  C07C43/225 ,  C07C43/23 ,  C07C51/353 ,  C07C63/14 ,  C07C63/66 ,  C07C65/24 ,  C07C65/28 ,  C07C67/343 ,  C07C69/76 ,  C07C69/94 ,  C07C309/73 ,  C07C317/44 ,  C07C317/46 ,  C07C319/20 ,  C07C323/52 ,  C07C323/56 ,  C07C323/62 ,  C07C323/65 ,  C07D257/06 ,  C07F7/18 ,  C07F9/54

CPC分类号： C07F9/5456 ,  C07C309/73 ,  C07C323/56 ,  C07C43/225 ,  C07C43/23 ,  C07C63/14 ,  C07C65/24 ,  C07F7/1852 ,  C07F9/5407

摘要： An alkenoic acid derivative of the formula ##STR1## in which X and Y are identical or different and represent sulfur, sulfoxide, sulfone, an alkylene chain, --SCH.sub.2 --, or oxygen or a direct bond,W represents --CH.dbd.CH--or --CH.sub.2 --CH.sub.2 --,o represents a number 1 to 5,A and B are identical or different and represent carboxyl, carboxymethylene, tetrazolyl or tetrazolylmethylene, or --CO.sub.2 R.sup.9 or --CH.sub.2 CO.sub.2 R.sup.9 or --CONR.sup.10 R.sup.11 or nitrilen represents a number 1 to 10,m represents a number 0 to 7,T and Z are identical or different and represent oxygen or a direct bond andR.sup.2, R.sup.3, R.sup.8 are identical or different and represent hydrogen, alkyl, alkoxy, halogen, trifluoromethyl, trifluoromethoxy, cyano or nitro andR.sup.9 is lower alkyl and R.sup.10 and R.sup.11 are hydrogen, lower alkyl, alkylsulfonyl or arylsulfonyl or together are an alkylene chain to form a ringand pharmaceutically acceptable salts thereof. Such alkenoic acid derivatives are useful as leucotriene disease antagonists.

摘要翻译： 其中X和Y相同或不同并表示硫，亚砜，砜，亚烷基链，-SCH 2 - 或氧或直接键的式（I）的链烯酸衍生物，W表示-CH = CH-或-CH 2 -CH 2 - ，o表示数1至5，A和B相同或不同，表示羧基，羧基亚甲基，四唑基或四唑基亚甲基，或-CO 2 R 9或-CH 2 CO 2 R 9或-CONR 10 R 11或腈n表示1 至10，m表示0至7的数，T和Z相同或不同，表示氧或直接键，R2，R3，R8相同或不同，表示氢，烷基，烷氧基，卤素，三氟甲基，三氟甲氧基，氰基 或硝基，R 9为低级烷基，R 10和R 11为氢，低级烷基，烷基磺酰基或芳基磺酰基，或一起为形成环的亚烷基链及其药学上可接受的盐。 这样的链烯酸衍生物可用作白三烯类疾病拮抗剂。