摘要:
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要:
Disclosed is a method and a system of cryptographic currency user directory data and enhanced peer-verification ledger synthesis through multi-modal cryptographic key-address mapping. The method determines that a propagation packet is a transaction of a cryptographic currency and extracts both an IP address and an input key-address to determine that the input key-address is under a suspected control of a user of interest. The method also determines that a relayed key-address communicated between a user of interest and a correspondent is under the suspected control of the user of interest, and/or that and/or an exhibited key-address of a web content is under the suspected control of the user of interest. The suspected control may be added to an enhanced ledger data and/or a user directory data. The system implementing one or more of the methods includes a set of collections servers, a directory server, and a wide area network.
摘要:
The invention relates to a drug delivery device for providing local analgesia, local anesthesia or nerve blockade at a site in a human or animal in need thereof, the device comprising a fibrillar collagen matrix; and at least one drug substance selected from the group consisting of amino amide anesthetics, amino ester anesthetics and mixtures thereof, the at least one drug substance being substantially homogeneously dispersed in the collagen matrix, and the at least one drug substance being present in an amount sufficient to provide a duration of local analgesia, local anesthesia or nerve blockade which lasts for at least about one day after administration.
摘要:
A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.
摘要:
A relatively simple and inexpensive method to increase the operational lifetime of semiconductor laser diode elements and light emitting diodes (LEDs) is disclosed. The semiconductor laser diode element is placed in contact with a non-electrically conductive, chemically inert liquid. Preferably the liquid is a perfluorinated liquid. This results in a dramatically increased operational lifetime for the semiconductor laser diode element by preventing damaging heat build up to vulnerable areas of the laser diode element, such as the p-n junction. This method can work with the liquid being either static or flowing. The disclosed method can be used when the semiconductor laser diode element is used either as a laser itself or when it is used to optically pump another lasing element. The liquid can also be in contact with the lasing element, collimating lens, sub-mounts, or thermoelectric coolers in a lasing assembly. In a similar manner the operational lifetime and the range of power usage of an LED can be dramatically increased by placing the LED in contact with the non-electrically conductive, chemically inert liquid. Preferably the liquid is a perfluorinated liquid. The liquid can either be static or flowing. It is anticipated that this improvement will permit high power applications such as vehicle headlights to become powered by LEDs.
摘要:
The present invention is directed to rubber modified polymers which contains a functionalized (that is, highly grafted) rubber having a degree of grafting of at least 30 percent at the point of phase inversion and a specified amount of grafted vinyl aromatic polymer.
摘要:
This invention relates to cationically derivatized polycalactomannans obtained from cassia tora and cassia obtusifolia and to their use in personal care, household care, and institutional care compositions.
摘要:
A wader with pocket system includes a large center pocket has a hard outer cover and will hold a variety of accessories including fly dressing, fly holder, clippers, leaders, and leader wheels. The top of the hard cover opens and folds down to make a platform where a fisherman can choose what he needs and have an organized working area that will support his needed products without them falling in the water. An accessory pocket adjacent to the large center pocket used for containing accessories and equipment. A plurality of accessory holders, between 1″ and 3″ wide, each include a strip of waterproof, breathable fabric sewn to the wader at each end creating a loop suitable for holding accessories. The accessory holders can hold accessory insert sheaths that close at the bottom and are designed to take a variety of different accessory items that pertain to fishing, hunting, or other activities that require waders.
摘要:
Disclosed is a method and a system of cryptographic currency user directory data and enhanced peer-verification ledger synthesis through multi-modal cryptographic key-address mapping. The method determines that a propagation packet is a transaction of a cryptographic currency and extracts both an IP address and an input key-address to determine that the input key-address is under a suspected control of a user of interest. The method also determines that a relayed key-address communicated between a user of interest and a correspondent is under the suspected control of the user of interest, and/or that and/or an exhibited key-address of a web content is under the suspected control of the user of interest. The suspected control may be added to an enhanced ledger data and/or a user directory data. The system implementing one or more of the methods includes a set of collections servers, a directory server, and a wide area network.
摘要:
An interactive computer system and method for recruiting potential employee candidates. A user interactive Graphical User Interface (GUI) is provided on a computering device connected to a network for tracking and storing an employee candidate lifecycle with a potential employer. The GUI is preferably configured and operational to provide interactive promotional materials regarding an employment opportunity with a potential employer and establish a first video conference between the candidate and at least one representative of the potential employer.