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1.发明申请公开(公告)号：US20180344393A1
公开(公告)日：2018-12-06
申请号：US16000770
申请日：2018-06-05
Inventor： Sarah M. Gruba , James P. Rohl , Samuel J. Asirvatham , Suraj Kapa , Chance M. Witt , Deepak Padmanabhan , Christopher V. DeSimone
CPC classification number: A61B18/1492 , A61B2018/00232 , A61B2018/00238 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00488 , A61B2018/00529 , A61B2018/00577 , A61B2018/00613 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/1472 , A61N1/056
Abstract: Embodiments of the present disclosure relate to treating diseased tissue with ablation therapy. In an embodiment, an apparatus comprises a catheter having an elongate body extending between a proximal end and a distal end. The apparatus further includes a balloon structure arranged proximal to the distal end of the catheter, wherein the balloon structure has a first portion with a first permeability and a second portion with a second permeability such that the first permeability is different than the second permeability. In addition, the apparatus includes a first electrode arranged on or within the balloon structure and configured to: transmit current through the first portion, receive current transmitted through the first portion or both.
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2.发明申请公开(公告)号：US20190060632A1
公开(公告)日：2019-02-28
申请号：US16107046
申请日：2018-08-21
Inventor： Samuel J. Asirvatham , Suraj Kapa , Sarah M. Gruba , Douglas D. Pagoria , James P. Rohl , Chance M. Witt , Ammar M. Killu , Niyada Naksuk
IPC: A61N1/04 , A61N1/32 , A61B18/14 , A61B5/0472
Abstract: The present disclosure relates generally to electroporation systems and utilizing algorithms for electroporation pulse delivery including a patient's EKG/EGM monitoring. In some embodiments, an electroporation delivery system may include an electrocardiogram operatively connected to a processing device and a memory. One or more sensors may be operatively connected to the electrocardiogram for measuring electrical activity QRS complex of a patient's heart. One or more electrodes for treatment may be disposed in, at, or near the patient's heart, the one or more electrodes operatively connected to a pulse delivery mechanism. The electroporation delivery system may be configured to determine whether an electroporation pulse is deliverable to a patient based on the electrocardiogram.
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Patent Agency Ranking
公开(公告)号：US11426233B2
公开(公告)日：2022-08-30
申请号：US16000770
申请日：2018-06-05
Inventor： Sarah M. Gruba , James P. Rohl , Samuel J. Asirvatham , Suraj Kapa , Chance M. Witt , Deepak Padmanabhan , Christopher V. DeSimone
Abstract: Embodiments of the present disclosure relate to treating diseased tissue with ablation therapy. In an embodiment, an apparatus comprises a catheter having an elongate body extending between a proximal end and a distal end. The apparatus further includes a balloon structure arranged proximal to the distal end of the catheter, wherein the balloon structure has a first portion with a first permeability and a second portion with a second permeability such that the first permeability is different than the second permeability. In addition, the apparatus includes a first electrode arranged on or within the balloon structure and configured to: transmit current through the first portion, receive current transmitted through the first portion or both.
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公开(公告)号：US20180043056A1
公开(公告)日：2018-02-15
申请号：US15673274
申请日：2017-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： Danielle Frankson , Joseph T. Delaney, JR. , David R. Wulfman , Adam McGraw , Sarah M. Gruba
CPC classification number: A61L27/12 , A61F2/86 , A61L27/04 , A61L27/047 , A61L27/06 , A61L27/34 , A61L27/54 , A61L2300/102 , A61L2300/214 , A61L2300/404 , A61L2300/412 , C08L71/02
Abstract: A coating for a metal surface, the coating including poly(ethylene glycol) disposed on and covalently bonded directly to at least a portion of the metal surface, and a functional group grafted to at least a portion of the poly(ethylene glycol). The functional group is one of a bioactive functional group and an antimicrobial functional group.
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公开(公告)号：US10342899B2
公开(公告)日：2019-07-09
申请号：US15382712
申请日：2016-12-18
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, Jr. , David R. Wulfman , Sarah M. Gruba , Michael J. Kane
IPC: A61L27/34 , A61L31/10 , C09D165/04
Abstract: A coating for an implantable medical device includes a poly(monochloro-p-xylylene) coating formed on at least a portion of the implantable medical device, and a layer including at least one of poly(ethylene glycol) and a poly(ethylene glycol) derivative linked to the poly(monochloro-p-xylylene) coating by covalent bonds.
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公开(公告)号：US20220296881A1
公开(公告)日：2022-09-22
申请号：US17833269
申请日：2022-06-06
Inventor： Samuel J. Asirvatham , Suraj Kapa , Sarah M. Gruba , Douglas D. Pagoria , James P. Rohl , Chance M. Witt , Ammar M. Killu , Niyada Naksuk
Abstract: The present disclosure relates generally to electroporation systems and utilizing algorithms for electroporation pulse delivery including a patient's EKG/EGM monitoring. In some embodiments, an electroporation delivery system may include an electrocardiogram operatively connected to a processing device and a memory. One or more sensors may be operatively connected to the electrocardiogram for measuring electrical activity QRS complex of a patient's heart. One or more electrodes for treatment may be disposed in, at, or near the patient's heart, the one or more electrodes operatively connected to a pulse delivery mechanism. The electroporation delivery system may be configured to determine whether an electroporation pulse is deliverable to a patient based on the electrocardiogram.
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公开(公告)号：US20170173223A1
公开(公告)日：2017-06-22
申请号：US15382712
申请日：2016-12-18
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, JR. , David R. Wulfman , Sarah M. Gruba , Michael J. Kane
CPC classification number: A61L31/10 , A61L27/34 , A61L2420/02 , A61L2420/08 , C09D165/04 , A61L27/16 , C08L65/04 , A61L27/18 , C08L71/02
Abstract: A coating for an implantable medical device includes a poly(monochloro-p-xylylene) coating formed on at least a portion of the implantable medical device, and a layer including at least one of poly(ethylene glycol) and a poly(ethylene glycol) derivative linked to the poly(monochloro-p-xylylene) coating by covalent bonds.
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