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公开(公告)号：US10544966B2
公开(公告)日：2020-01-28
申请号：US15217902
申请日：2016-07-22
Applicant: Cepheid
Inventor： David Fromm , Tien Phan , Matthew Piccini
Abstract: Thermal control devices adapted to provide improved control and efficiency in temperature cycling are provided herein. Such thermal control device can include a thermoelectric cooler controlled in coordination with another thermal manipulation device to control an opposing face of the thermoelectric cooler and/or a microenvironment. Some such thermal control devices include a first and second thermoelectric cooler separated by a thermal capacitor. The thermal control devices can be configured in a planar configuration with a means for thermally coupling with a planar reaction vessel of a sample analyzer for use in thermal cycling in a polymerase chain reaction of the fluid sample in the reaction vessel. Methods of thermal cycling using such a thermal control devices are also provided.
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公开(公告)号：US11524301B2
公开(公告)日：2022-12-13
申请号：US16738944
申请日：2020-01-09
Applicant: Cepheid
Inventor： Douglas B Dority , Tien Phan , David Fromm , Richard J. Casler, Jr. , Dustin Dickens , Stuart Morita , Matthew Piccini
Abstract: Improved sub-assemblies and methods of control for use in a diagnostic assay system adapted to receive an assay cartridge are provided herein. Such sub-assemblies include: a brushless DC motor, a door opening/closing mechanism and cartridge loading mechanism, a syringe and valve drive mechanism assembly, a sonication horn, a thermal control device and optical detection/excitation device. Such systems can further include a communications unit configured to wirelessly communicate with a mobile device of a user so as to receive a user input relating to functionality of the system with respect to an assay cartridge received therein and relaying a diagnostic result relating to the assay cartridge to the mobile device.
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Patent Agency Ranking
公开(公告)号：US10562030B2
公开(公告)日：2020-02-18
申请号：US15217920
申请日：2016-07-22
Applicant: Cepheid
Inventor： Doug Dority , Tien Phan , David Fromm , Rick Casler , Dustin Dickens , Stuart Morita , Matthew Piccini
Abstract: Improved sub-assemblies and methods of control for use in a diagnostic assay system adapted to receive an assay cartridge are provided herein. Such sub-assemblies include: a brushless DC motor, a door opening/closing mechanism and cartridge loading mechanism, a syringe and valve drive mechanism assembly, a sonication horn, a thermal control device and optical detection/excitation device. Such systems can further include a communications unit configured to wirelessly communicate with a mobile device of a user so as to receive a user input relating to functionality of the system with respect to an assay cartridge received therein and relaying a diagnostic result relating to the assay cartridge to the mobile device.
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公开(公告)号：US20230166263A1
公开(公告)日：2023-06-01
申请号：US18054729
申请日：2022-11-11
Applicant: Cepheid
Inventor： Douglas B. Dority , Tien Phan , David Fromm , Richard J. Casler, JR. , Dustin Dickens , Stuart Morita , Matthew Piccini
CPC classification number: B01L7/52 , H02P27/06 , H02P6/182 , G01N35/1095 , G01N35/00871 , B01L3/50273 , G01N35/1016 , B01L2300/023 , B01L2300/027 , B01L2300/1822 , B01L2300/0663 , B01L2300/1894 , B01L2400/0436 , B01L2400/0496 , G01N2201/0256 , G01N2035/00019 , G01N2035/00356 , B01L2200/04 , G01N2035/00316 , G01N2201/0221 , G01N2800/00 , B01L2200/0647 , B01L2400/0439 , B01L2200/025 , B01L2200/143 , B01L2300/1827 , B01L2300/14 , G01N33/4875
Abstract: Improved sub-assemblies and methods of control for use in a diagnostic assay system adapted to receive an assay cartridge are provided herein. Such sub-assemblies include: a brushless DC motor, a door opening/closing mechanism and cartridge loading mechanism, a syringe and valve drive mechanism assembly, a sonication horn, a thermal control device and optical detection/excitation device. Such systems can further include a communications unit configured to wirelessly communicate with a mobile device of a user so as to receive a user input relating to functionality of the system with respect to an assay cartridge received therein and relaying a diagnostic result relating to the assay cartridge to the mobile device.
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公开(公告)号：US11073310B2
公开(公告)日：2021-07-27
申请号：US16712797
申请日：2019-12-12
Applicant: Cepheid
Inventor： David Fromm , Tien Phan , Matthew Piccini
Abstract: Thermal control devices adapted to provide improved control and efficiency in temperature cycling are provided herein. Such thermal control device can include a thermoelectric cooler controlled in coordination with another thermal manipulation device to control an opposing face of the thermoelectric cooler and/or a microenvironment. Some such thermal control devices include a first and second thermoelectric cooler separated by a thermal capacitor. The thermal control devices can be configured in a planar configuration with a means for thermally coupling with a planar reaction vessel of a sample analyzer for use in thermal cycling in a polymerase chain reaction of the fluid sample in the reaction vessel. Methods of thermal cycling using such a thermal control devices are also provided.
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公开(公告)号：US12196460B2
公开(公告)日：2025-01-14
申请号：US17338264
申请日：2021-06-03
Applicant: Cepheid
Inventor： David Fromm , Tien Phan , Matthew Piccini
Abstract: Thermal control devices adapted to provide improved control and efficiency in temperature cycling are provided herein. Such thermal control device can include a thermoelectric cooler controlled in coordination with another thermal manipulation device to control an opposing face of the thermoelectric cooler and/or a microenvironment. Some such thermal control devices include a first and second thermoelectric cooler separated by a thermal capacitor. The thermal control devices can be configured in a planar configuration with a means for thermally coupling with a planar reaction vessel of a sample analyzer for use in thermal cycling in a polymerase chain reaction of the fluid sample in the reaction vessel. Methods of thermal cycling using such a thermal control devices are also provided.
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公开(公告)号：US20210364196A1
公开(公告)日：2021-11-25
申请号：US17338264
申请日：2021-06-03
Applicant: Cepheid
Inventor： David Fromm , Tien Phan , Matthew Piccini
Abstract: Thermal control devices adapted to provide improved control and efficiency in temperature cycling are provided herein. Such thermal control device can include a thermoelectric cooler controlled in coordination with another thermal manipulation device to control an opposing face of the thermoelectric cooler and/or a microenvironment. Some such thermal control devices include a first and second thermoelectric cooler separated by a thermal capacitor. The thermal control devices can be configured in a planar configuration with a means for thermally coupling with a planar reaction vessel of a sample analyzer for use in thermal cycling in a polymerase chain reaction of the fluid sample in the reaction vessel. Methods of thermal cycling using such a thermal control devices are also provided.
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