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    BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME
    1.
    发明申请
    BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME 审中-公开
    检测反应物的生物学和方法

    公开(公告)号：US20110091905A1

    公开(公告)日：2011-04-21

    申请号：US12893166

    申请日：2010-09-29

    申请人： Chil Seong AH ,  Gun Yong Sung ,  Wan Joong Kim ,  Bong Kyu Kim ,  Jong Cheol Hong ,  Chul Huh ,  Seon Hee Park

    发明人： Chil Seong AH ,  Gun Yong Sung ,  Wan Joong Kim ,  Bong Kyu Kim ,  Jong Cheol Hong ,  Chul Huh ,  Seon Hee Park

    IPC分类号： G01N33/53 ,  G01N21/17 ,  C12M1/34 ,  G01N30/00

    CPC分类号： G01N33/5302 ,  G01N21/31

    摘要： Provided are a biochip and a method of detecting a reaction from the biochip. This method includes preparing a first mixture solution of polyvinylpyrrolidone (PVP) and a sample including target molecules, measuring absorbance or transmittance of the first mixture solution, preparing a second mixture solution including the PVP, the sample, and a receptor of the target molecules, measuring absorbance or transmittance of the second mixture solution, and calculating an absorbance or transmittance difference between the first mixture solution and the second mixture solution. Thus, it is possible to reduce the production cost of the biochip by inducing a reaction of an antigen and an antibody using PVP. Further, it is possible to detect an accurate quantity of the antigen by analyzing a quantity of antigen on the basis of the absorbance or transmittance difference.

    摘要翻译： 提供了一种生物芯片和从生物芯片检测反应的方法。 该方法包括制备聚乙烯吡咯烷酮（PVP）的第一混合溶液和包含靶分子的样品，测量第一混合溶液的吸光度或透射率，制备包含PVP，样品和靶分子的受体的第二混合溶液， 测量第二混合溶液的吸光度或透射率，并计算第一混合溶液和第二混合溶液之间的吸光度或透射率差异。 因此，通过使用PVP诱导抗原和抗体的反应，可以降低生物芯片的生产成本。 此外，可以通过基于吸光度或透射率差异分析抗原量来检测精确量的抗原。

    PHOTONIC BIOSENSOR, PHOTONIC BIOSENSOR ARRAY, AND METHOD OF DETECTING BIOMATERIALS USING THE SAME
    3.
    发明申请
    PHOTONIC BIOSENSOR, PHOTONIC BIOSENSOR ARRAY, AND METHOD OF DETECTING BIOMATERIALS USING THE SAME 审中-公开
    光电生物传感器，光电生物传感器阵列，以及使用该方法检测生物体的方法

    公开(公告)号：US20110129846A1

    公开(公告)日：2011-06-02

    申请号：US12860796

    申请日：2010-08-20

    申请人： Chul Huh ,  Kyung Hyun Kim ,  Bong Kyu Kim ,  Hyun Sung Ko ,  Wan Joong Kim ,  Jong Cheol Hong ,  Gun Yong Sung ,  Seon Hee Park

    发明人： Chul Huh ,  Kyung Hyun Kim ,  Bong Kyu Kim ,  Hyun Sung Ko ,  Wan Joong Kim ,  Jong Cheol Hong ,  Gun Yong Sung ,  Seon Hee Park

    IPC分类号： G01N33/53 ,  G01N33/543 ,  C12M1/34 ,  G01N30/96

    CPC分类号： G01N33/54373 ,  B01L3/5027 ,  B01L2300/0877 ,  G01N21/05 ,  G01N21/253 ,  G01N21/554 ,  G01N21/7703 ,  G01N2021/0346

    摘要： A photonic biosensor, a photonic biosensor array, and a method of detecting a bio-material using the same are provided. The photonic biosensor includes a light emitting diode configured to emit light, a photodiode (PD), an optical fiber configured to connect the light emitting diode with the PD, and a micro-fluidic channel disposed on the optical fiber. Bio-antibodies or aptamers are fixed to the surface of the optical fiber, and the micro-fluidic channel includes gold (Au) nanoparticles to which bio-antibodies or aptamers are fixed. The photonic biosensor may be configured using absorption of surface plasmons in Au nanoparticles with respect to light traveling through the surface of the optical fiber configured to connect the light emitting diode with the PD, thus simplifying the manufacture of the biosensor and reducing the manufacturing cost.

    摘要翻译： 提供了光子生物传感器，光子生物传感器阵列和使用其的生物材料的检测方法。 光子生物传感器包括被配置为发光的发光二极管，光电二极管（PD），被配置为将发光二极管与PD连接的光纤以及设置在光纤上的微流体通道。 生物抗体或适配体固定在光纤表面，微流体通道包括固定有生物抗体或适体的金（Au）纳米颗粒。 光子生物传感器可以使用Au纳米颗粒中的表面等离子体的吸收来配置，该光束传播通过配置成将发光二极管与PD连接的光纤的表面传播的光，从而简化了生物传感器的制造并降低了制造成本。

    Apparatus for detecting biomaterials and method for detecting biomaterials by using the apparatus
    6.
    发明授权
    Apparatus for detecting biomaterials and method for detecting biomaterials by using the apparatus 失效
    用于检测生物材料的装置和通过使用该装置检测生物材料的方法

    公开(公告)号：US08199325B2

    公开(公告)日：2012-06-12

    申请号：US12534464

    申请日：2009-08-03

    申请人： Wanjoong Kim ,  Chul Huh ,  Hyunsung Ko ,  Kyung Hyun Kim ,  Gun Yong Sung ,  Seon Hee Park ,  Bong Kyu Kim ,  Chil Seong Ah ,  Ansoon Kim

    发明人： Wanjoong Kim ,  Chul Huh ,  Hyunsung Ko ,  Kyung Hyun Kim ,  Gun Yong Sung ,  Seon Hee Park ,  Bong Kyu Kim ,  Chil Seong Ah ,  Ansoon Kim

    IPC分类号： G01N21/55

    CPC分类号： G01N21/554 ,  G01N21/33

    摘要： Provided are an apparatus and method for detecting biomaterials. The apparatus for detecting the biomaterials includes a light source unit, a biomaterial reacting unit, and a detection unit detecting. The light source unit provides incident light. The biomaterial reacting unit includes a substrate and metal nanoparticles spaced from the substrate. The surface plasmon resonance phenomenon is induced on surfaces of the metal nanoparticles by the incident light. First detecting molecules specifically binding to target molecules are immobilized to the surfaces of the metal nanoparticles. The detection unit detects a resonance wavelength of emission light emitted from the metal nanoparticles by the surface plasmon resonance phenomenon.

    摘要翻译： 提供了用于检测生物材料的装置和方法。 用于检测生物材料的装置包括光源单元，生物材料反应单元和检测单元检测。 光源单元提供入射光。 生物材料反应单元包括与衬底间隔开的衬底和金属纳米颗粒。 通过入射光在金属纳米颗粒的表面上诱导表面等离子体共振现象。 首先检测与靶分子特异性结合的分子被固定在金属纳米粒子的表面。 检测单元通过表面等离子体共振现象检测从金属纳米颗粒发射的发射光的共振波长。

    CARTRIDGE FOR MEASURING BIOLOGICAL SAMPLE COMPONENT AND APPARATUS FOR MEASURING BIOLOGICAL SAMPLE COMPONENT
    7.
    发明申请
    CARTRIDGE FOR MEASURING BIOLOGICAL SAMPLE COMPONENT AND APPARATUS FOR MEASURING BIOLOGICAL SAMPLE COMPONENT 审中-公开
    用于测量生物样品组分的仪器和用于测量生物样品组分的装置

    公开(公告)号：US20110293479A1

    公开(公告)日：2011-12-01

    申请号：US12950964

    申请日：2010-11-19

    申请人： Jong Cheol HONG ,  Chul Huh ,  Bong Kyu Kim ,  Chil Seong Ah ,  Yo Han Choi ,  Gun Yong Sung

    发明人： Jong Cheol HONG ,  Chul Huh ,  Bong Kyu Kim ,  Chil Seong Ah ,  Yo Han Choi ,  Gun Yong Sung

    IPC分类号： G01N21/00 ,  G01N33/48

    CPC分类号： G01N21/03 ,  G01N2021/0325 ,  G01N2021/0346

    摘要： A cartridge for measuring a biological sample component and an apparatus for measuring a biological sample component are provided. The cartridge for measuring a biological sample component includes: an upper cartridge having a first chamber storing a biological sample, a first channel connected to the first chamber and delivering air pressure to the first chamber, and a third channel transferring the biological sample; and a lower cartridge having a third chamber storing a first reagent, a fifth chamber storing a second reagent, a fifth channel connecting the third and fifth chambers and transferring the second reagent to the third chamber, an eleventh channel delivering the biological sample delivered through the third channel to the third chamber, and a thirteenth channel delivering air pressure to the fifth chamber, wherein when the upper and lower cartridges are bounded by an external force, the third channel and the eleventh channel are connected.

    摘要翻译： 提供了用于测量生物样品组分的盒和用于测量生物样品组分的装置。 用于测量生物样品组分的盒包括：具有存储生物样品的第一室的上盒，连接到第一室的第一通道并将空气压力输送到第一室，以及传送生物样品的第三通道; 以及具有第三室的下部盒存储第一试剂，存储第二试剂的第五室，连接第三和第五室的第五通道并将第二试剂转移到第三室，第十一通道，其输送通过 第三通道到第三室，以及第十三通道，将空气压力传送到第五室，其中当上部和下部盒被外力界定时，第三通道和第十一通道连接。

    Apparatus for fixing plastic sheet and method of fabricating nano pattern on plastic sheet using the same
    9.
    发明授权
    Apparatus for fixing plastic sheet and method of fabricating nano pattern on plastic sheet using the same 有权
    用于固定塑料片的装置和使用其制造在塑料片上的纳米图案的方法

    公开(公告)号：US08292608B2

    公开(公告)日：2012-10-23

    申请号：US12743117

    申请日：2008-05-21

    申请人： Kyung Hyun Kim ,  Chul Huh ,  Hyun Sung Ko ,  Jong Cheol Hong ,  Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park

    发明人： Kyung Hyun Kim ,  Chul Huh ,  Hyun Sung Ko ,  Jong Cheol Hong ,  Wan Joong Kim ,  Gun Yong Sung ,  Seon Hee Park

    IPC分类号： B29C43/32

    CPC分类号： H01L21/6838 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

    摘要： There are provided an apparatus for fixing a plastic sheet which fixes a plastic sheet to fabricate a nano pattern and a method of fabricating a nano pattern on a plastic sheet using the same. The apparatus for fixing a plastic sheet includes: a pair of planar metal guide rings interposingly fixing a plastic sheet from above and below, respectively; and a sheet fixing chuck including: a ring fixer sucking the pair of planar metal guide rings through a vacuum groove to be fixed thereto; and a sheet fixer having a plurality of vacuum pin holes formed therein, the vacuum pin holes sucking a bottom of the plastic sheet fixed by the planar metal guide rings. The apparatus allows fabrication of the nano pattern on the plastic sheet having less roughness than that of a semiconductor substrate or a glass substrate.

    摘要翻译： 提供了一种用于固定塑料片以制造纳米图案的塑料片的设备和使用其形成在塑料片上的纳米图案的方法。 用于固定塑料片的装置包括：分别从上下固定塑料片的一对平面金属导向环; 以及片状固定卡盘，其包括：环形固定器，其通过真空槽吸附所述一对平面金属导向环以固定到其上; 以及具有形成在其中的多个真空针孔的片固定器，所述真空针孔吸附由所述平面金属导向环固定的所述塑料片的底部。 该装置允许在塑料片上制造具有比半导体衬底或玻璃衬底更小的粗糙度的纳米图案。