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公开(公告)号：US20050252607A1
公开(公告)日：2005-11-17
申请号：US11168768
申请日：2005-06-28
CPC分类号： C09J9/00
摘要： A process for bonding at least two substrates with a hotmelt adhesive using microwave energy is provided. The process includes applying a microwave-activatable primer to a least one of the substrates and applying a hotmelt adhesive to a least one of the substrates. The method also includes pressing the substrates together so that the microwave-activatable primer and the hot melt adhesive are between the substrates, and exposing at least the microwave-activatable primer to microwaves to heat the hotmelt adhesive. The present invention also provides a process for spraying a hot melt adhesive onto a substrate where the hot melt adhesive includes nanoparticles having ferromagnetic, ferrimagnetic, superparamagnetic or piezoelectric properties.
摘要翻译： 提供了一种使用微波能量用热熔粘合剂粘合至少两个基底的方法。 该方法包括将微波激活的底漆施加到至少一个基底并将热熔粘合剂施加到至少一个基底。 该方法还包括将基底压在一起，使得微波激活的底漆和热熔粘合剂位于基底之间，并将至少微波激活的底漆暴露于微波以加热热熔粘合剂。 本发明还提供了一种将热熔粘合剂喷涂到基底上的方法，其中热熔粘合剂包括具有铁磁性，亚铁磁性，超顺磁性或压电性质的纳米颗粒。
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2.发明授权Ferromagnetic resonance excitation and its use for heating substrates that are filled with particles 失效铁磁共振激发及其用于加热填充有颗粒的衬底的用途公开(公告)号：US07273580B2
公开(公告)日：2007-09-25
申请号：US10343405
申请日：2001-07-24
CPC分类号： C09J5/06 , C08G2170/20 , C08K3/08 , C09J2205/302 , H05B6/80 , Y10T156/1158
摘要： Process for heating a substrate, which contains, relative to the total weight of the substrate, 0.1 to 70 wt. % of metallic, magnetic, ferrimagnetic, ferromagnetic, antiferromagnetic or superparamagnetic particles having an average particle size of between 1 and 5000 nm, wherein the substrate is exposed to electromagnetic radiation, characterized in that the electromagnetic radiation comprises microwave radiation with a frequency in the range from 1 to 300 GHz and the substrate is simultaneously exposed to a direct-current magnetic field, the field strength of which is at least twice the strength of the earth's magnetic field; use of the process for producing or detaching adhesive bonds; device for the simultaneous production of microwave radiation with a frequency within the range from 1 to 300 GHz and a direct-current magnetic field, the field strength of which is at least twice the strength of the earth's magnetic field.
摘要翻译： 用于加热基材的方法，其含有相对于基材的总重量为0.1-70wt。 具有平均粒度在1至5000nm之间的金属，磁性，铁磁性，铁磁性，反铁磁性或超顺磁性颗粒的百分比，其中所述衬底暴露于电磁辐射，其特征在于，所述电磁辐射包括频率在该范围内的微波辐射 从1到300GHz，衬底同时暴露于直流磁场，其场强至少是地球磁场强度的两倍; 使用生产或分离粘合剂粘合剂的方法; 用于同时产生频率在1至300GHz范围内的微波辐射的装置，以及其场强至少是地球磁场强度的两倍的直流磁场。
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公开(公告)号：US07407704B2
公开(公告)日：2008-08-05
申请号：US10930571
申请日：2004-08-31
申请人： Christian Kirsten
发明人： Christian Kirsten
CPC分类号： C09J5/02 , C09J5/06 , C09J9/00 , C09J11/04 , C09J2205/302 , Y10T156/1153 , Y10T428/25 , Y10T428/256 , Y10T428/258
摘要： The reversible separation of bonded joints by applying alternating electromagnetic fields is described. The bonded joint consists of at least one primer layer which contains nanoscale particles which have ferromagnetic, ferrimagnetic, superparamagnetic or piezoelectric properties. As a result of the alternating electromagnetic fields, large amounts of localised heat are produced in the primer layer of the bonded joint. This localised heat input causes, in the case of adjacent thermoplastic adhesive layers, softening of the thermoplastic binder. If thermoset adhesives are adjacent to the boundary layer of the primer, then the cross-linked structure in the binder matrix is broken up due to the high degree of localised warming. In both cases quasi-adhesive substrate separation with a low energy input is enabled as a result of the high localised warming of the boundary layer.
摘要翻译： 描述了通过施加交变电磁场的接合接头的可逆分离。 粘合接头由至少一个底漆层组成，其包含具有铁磁性，亚铁磁性，超顺磁性或压电性质的纳米级颗粒。 作为交变电磁场的结果，在接合接头的底漆层中产生大量的局部热。 在相邻的热塑性粘合剂层的情况下，该局部热输入导致热塑性粘合剂的软化。 如果热固性粘合剂与底漆的边界层相邻，则由于高度的局部变暖，粘结剂基质中的交联结构被破坏。 在这两种情况下，由于边界层的高度局部变暖，能够实现具有低能量输入的准粘性基板分离。
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公开(公告)号：US07147742B2
公开(公告)日：2006-12-12
申请号：US10343297
申请日：2001-07-25
申请人： Christian Kirsten
发明人： Christian Kirsten
IPC分类号： B32B37/06
CPC分类号： C09J5/06 , B29C35/08 , B29C65/3612 , B29C65/4815 , B29C65/4835 , B29C65/484 , B29C65/4845 , B29C65/485 , B29C65/4855 , B29C65/4875 , B29C66/742 , B29K2105/162
摘要： A process for heating particle filled adhesive compositions by using an electrical, magnetic or electromagnetic alternating field. Nanoscale particles are employed having ferromagnetic, ferrimagnetic, superparamagnetic or piezoelectric properties. These particles more efficiently convert the electrical, magnetic or electromagnetic input into heat to cure the adhesive composition. With this process not only is the rate of cure accelerated but the various properties of the adhesive are less likely to be adversely affected.
摘要翻译： 通过使用电，磁或电磁交变场来加热颗粒填充的粘合剂组合物的方法。 使用具有铁磁性，亚铁磁性，超顺磁性或压电性质的纳米级颗粒。 这些颗粒更有效地将电，磁或电磁输入转换成热量以固化粘合剂组合物。 通过这种方法，固化速度不仅加快了粘合剂的各种性能，而且不太可能受到不利影响。
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5.发明申请Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur 审中-公开用于治疗，诊断和预防异常蛋白质结构发生的疾病的活性物质公开(公告)号：US20050239808A1
公开(公告)日：2005-10-27
申请号：US10514015
申请日：2003-05-09
申请人： Thomas Schrader , Detlev Riesner , Petra Rzepecki , Luitgard Nagel-Steger , Mark Wehner , Christian Kirsten , Oliver Molt , Reza Zadmard , Katja Aschermann
发明人： Thomas Schrader , Detlev Riesner , Petra Rzepecki , Luitgard Nagel-Steger , Mark Wehner , Christian Kirsten , Oliver Molt , Reza Zadmard , Katja Aschermann
IPC分类号： A61P25/28 , C07D231/40 , C07D401/14 , A61K31/522 , A61K31/416 , A61K31/4196 , A61K31/4709 , C07D473/02 , C07D43/02
CPC分类号： C07D231/40 , C07D401/14
摘要： The invention on hand refers to diseases associated with abnormal protein structures, including Alzheimer's disease, Creutzfeldt-Jakob's disease, BSE and other prion-associated diseases. It is the task of the invention on hand to provide new active agents preventing the formation of amyloid plaques and to dissolve existing plaques, such agents being convenient for therapy, diagnosis and prophylaxis of diseases that are associated with abnormal protein structures. This task is performed in terms of the current invention by heterocyclic or aromatic agents with a rigid structure and a donor-acceptor-donor pattern (DAD), the latter being formed by donors and acceptors of hydrogen bridge linkages which comply with the β-sheet structure of the peptide or protein and thus fit as binding partners. The heterocyclic or aromatic agents are available at least as dimers. They recognise peptides and proteins with a β-sheet structure, form stable complexes with them and inhibit their aggregation to β-amyloid plaques. Furthermore, the new active agents are able to dissolve β-amyloid plaques that already exist. Another task of the current invention is to provide methods for the synthesis of said heterocyclic or aromatic compounds.
摘要翻译： 手头的发明是指与异常蛋白质结构相关的疾病，包括阿尔茨海默病，克雅氏病，疯牛病和其他朊病毒相关疾病。 本发明的任务是提供防止淀粉样蛋白斑块形成和溶解现有斑块的新的活性剂，所述药剂便于治疗，诊断和预防与异常蛋白质结构相关的疾病。 根据本发明，通过具有刚性结构和供体 - 受体 - 给体模式（DAD）的杂环或芳族化合物来执行该任务，后者由供体和符合β-折叠板的氢桥连接体的受体形成 肽或蛋白质的结构，因此适合作为结合配偶体。 杂环或芳族试剂至少可以作为二聚体获得。 它们识别具有β-折叠结构的肽和蛋白质，与它们形成稳定的复合物并抑制它们与β-淀粉样蛋白斑的聚集。 此外，新的活性剂能够溶解已经存在的β-淀粉样斑块。 本发明的另一个任务是提供合成所述杂环或芳族化合物的方法。
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公开(公告)号：US20050228096A1
公开(公告)日：2005-10-13
申请号：US10381830
申请日：2001-09-19
IPC分类号： B32B27/08 , C09J11/04 , C09J175/04 , C08K3/18
CPC分类号： C09J175/04 , B32B27/08 , C09J11/04
摘要： An adhesive composition and the use thereof to produce barrier-effect composite films. The adhesive composition contains polymer binders and fillers having a platelet-like crystallite structure with an aspect ratio of >100. The composite films produced with this adhesive exhibit barrier characteristics against the migration of oxygen, flavors and water vapor. These films are useful for packaging foods and medicaments.
摘要翻译： 粘合剂组合物及其制备屏障效应复合膜的用途。 粘合剂组合物含有聚合物粘合剂和具有> 100的长径比的片状微晶结构的填料。 用这种粘合剂生产的复合膜表现出抵抗氧气，香料和水蒸气迁移的阻挡特性。 这些薄膜可用于包装食品和药物。
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公开(公告)号：US20050039848A1
公开(公告)日：2005-02-24
申请号：US10930571
申请日：2004-08-31
申请人： Christian Kirsten
发明人： Christian Kirsten
CPC分类号： C09J5/02 , C09J5/06 , C09J9/00 , C09J11/04 , C09J2205/302 , Y10T156/1153 , Y10T428/25 , Y10T428/256 , Y10T428/258
摘要： The reversible separation of bonded joints by applying alternating electromagnetic fields is described. The bonded joint consists of at least one primer layer which contains nanoscale particles which have ferromagnetic, ferrimagnetic, superparamagnetic or piezoelectric properties. As a result of the alternating electromagnetic fields, large amounts of localised heat are produced in the primer layer of the bonded joint. This localised heat input causes, in the case of adjacent thermoplastic adhesive layers, softening of the thermoplastic binder. If thermoset adhesives are adjacent to the boundary layer of the primer, then the cross-linked structure in the binder matrix is broken up due to the high degree of localised warming. In both cases quasi-adhesive substrate separation with a low energy input is enabled as a result of the high localised warming of the boundary layer.
摘要翻译： 描述了通过施加交变电磁场的接合接头的可逆分离。 粘合接头由至少一个底漆层组成，其包含具有铁磁性，亚铁磁性，超顺磁性或压电性质的纳米级颗粒。 作为交变电磁场的结果，在接合接头的底漆层中产生大量的局部热。 在相邻的热塑性粘合剂层的情况下，该局部热输入导致热塑性粘合剂的软化。 如果热固性粘合剂与底漆的边界层相邻，则由于高度的局部变暖，粘结剂基质中的交联结构被破坏。 在这两种情况下，由于边界层的高度局部变暖，能够实现具有低能量输入的准粘性基板分离。
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