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1.Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents 审中-公开
标题翻译: 四氢萘衍生物,其制备方法及其作为抗炎剂的用途公开(公告)号:US20070129359A1
公开(公告)日:2007-06-07
申请号:US11414556
申请日:2006-05-01
申请人: Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
发明人: Christoph Huwe , Werner Skuballa , Duy Nguyen , Heike Schaecke , Wheeseong Lee
IPC分类号: A61K31/538 , A61K31/498 , A61K31/4745 , A61K31/4704 , A61K31/404 , A61K31/4035
CPC分类号: C07C233/74 , C07C217/74 , C07C275/28 , C07C311/20 , C07C2602/10
摘要: The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (I) processes for their preparation and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及式(I)的多取代四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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2.Substituted pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译: 取代的戊醇,其生产方法及其作为抗炎剂的用途公开(公告)号:US20050143415A1
公开(公告)日:2005-06-30
申请号:US10957742
申请日:2004-10-05
申请人: Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke
发明人: Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke
IPC分类号: A61K31/47 , C07D215/38 , C07D217/22
CPC分类号: C07D215/38 , C07D217/22
摘要: The invention relates to substituted pentanols, a process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及取代戊醇,其制备方法及其作为抗炎剂的用途。
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3.Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 失效
标题翻译: 四氢萘衍生物,其生产方法及其作为抗炎剂的用途公开(公告)号:US20050209324A1
公开(公告)日:2005-09-22
申请号:US10961406
申请日:2004-10-12
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A61K31/135 , A61K31/195 , A61K31/277
CPC分类号: C07D209/34 , C07D213/74 , C07D215/04 , C07D215/227 , C07D215/38 , C07D215/60 , C07D217/24 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/64 , C07D307/88 , C07D405/12 , C07D471/04
摘要: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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4.Rearranged pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译: 重排戊醇,其生产过程及其作为抗炎剂的用途公开(公告)号:US20050131226A1
公开(公告)日:2005-06-16
申请号:US10960757
申请日:2004-10-08
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A61P29/00 , C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/68 , C07D311/76 , C07D471/02 , C07D498/02
CPC分类号: C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D311/76
摘要: The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及式I化合物,其制备方法及其作为抗炎剂的用途。
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5.Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 失效
标题翻译: 四氢萘衍生物,其生产方法及其作为抗炎剂的用途公开(公告)号:US07662821B2
公开(公告)日:2010-02-16
申请号:US10962169
申请日:2004-10-12
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A61K31/497 , A61K31/44 , A61K31/415 , A61K31/275 , C07D239/72 , C07D237/26 , C07D209/04 , C07C255/49 , C07C62/38 , C07C211/44
CPC分类号: C07D277/62 , C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74
摘要: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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6.Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 失效
标题翻译: 四氢萘衍生物,其生产方法及其作为抗炎剂的用途公开(公告)号:US07659297B2
公开(公告)日:2010-02-09
申请号:US10960754
申请日:2004-10-08
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A01N43/56 , C07D231/02 , C07D231/54 , C07D487/00
CPC分类号: C07D209/34 , C07D209/46 , C07D215/38 , C07D217/24 , C07D231/56 , C07D237/30 , C07D239/74 , C07D277/62
摘要: The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as antiinflammatory agents.
摘要翻译: 本发明涉及式(I)的多取代四氢萘衍生物的制备方法及其作为抗炎剂的用途。
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7.Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 审中-公开
标题翻译: 亚烷基 - 四氢萘衍生物,其制备方法及其作为抗炎剂的用途公开(公告)号:US20060084652A1
公开(公告)日:2006-04-20
申请号:US11222250
申请日:2005-09-09
申请人: Stefan Baeurle , Markus Berger , Stefan Jaroch , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Heike Schaecke , Norbert Schmees , Werner Skuballa
发明人: Stefan Baeurle , Markus Berger , Stefan Jaroch , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Heike Schaecke , Norbert Schmees , Werner Skuballa
IPC分类号: A61K31/517 , A61K31/502 , A61K31/4704
CPC分类号: C07D247/00
摘要: The invention relates to alkylidene-tetrahydronaphthalene derivatives of general formula (I), process for their production, and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及通式(I)的亚烷基 - 四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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8.MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS 失效
标题翻译: 多取代四氢萘基衍生物及其生产工艺及其作为抗炎剂的用途公开(公告)号:US20100144742A1
公开(公告)日:2010-06-10
申请号:US12642121
申请日:2009-12-18
申请人: Hartmut REHWINKEL , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut REHWINKEL , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A61K31/517 , A61K31/472 , A61K31/47 , C07D237/30 , C07D239/72 , C07D215/00 , A61P29/00
CPC分类号: C07D217/24 , A61K31/47 , A61K31/472 , A61K31/517 , C07C215/44 , C07C255/58 , C07C2602/10 , C07D209/34 , C07D209/46 , C07D213/74 , C07D215/04 , C07D215/22 , C07D215/227 , C07D215/38 , C07D215/48 , C07D215/58 , C07D231/56 , C07D237/32 , C07D239/74 , C07D239/76 , C07D277/64 , C07D307/88 , C07D317/70 , C07D405/12 , C07D471/04
摘要: The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及式(I)的多取代四氢萘衍生物的制备方法及其作为抗炎剂的用途。
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9.Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 失效
标题翻译: 四氢萘衍生物,其生产方法及其作为抗炎剂的用途公开(公告)号:US07638515B2
公开(公告)日:2009-12-29
申请号:US10961406
申请日:2004-10-12
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: A61K31/50 , A61K31/47 , C07D237/02 , C07D239/70 , C07D411/12 , C07D453/04 , C07D272/22 , C07C211/03 , C07C62/38 , C07C255/02
CPC分类号: C07D209/34 , C07D213/74 , C07D215/04 , C07D215/227 , C07D215/38 , C07D215/60 , C07D217/24 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/64 , C07D307/88 , C07D405/12 , C07D471/04
摘要: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及四氢萘衍生物,其制备方法及其作为抗炎剂的用途。
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10.Rearranged pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译: 重排戊醇,其生产过程及其作为抗炎剂的用途公开(公告)号:US07442794B2
公开(公告)日:2008-10-28
申请号:US10960757
申请日:2004-10-08
申请人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
发明人: Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa
IPC分类号: C07D237/00 , C07D239/00 , C07D453/00 , C07D217/00 , C07D231/00 , C07D209/00 , C07D311/00 , C07D407/00 , C07D493/00
CPC分类号: C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D311/76
摘要: The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.
摘要翻译: 本发明涉及式I化合物,其制备方法及其作为抗炎剂的用途。
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