Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries
    1.
    发明授权
    Viscosity and mass sensor for the high-throughput synthesis, screening and characterization of combinatorial libraries 失效
    用于高通量合成,筛选和表征组合文库的粘度和质量传感器

    公开(公告)号:US06602714B1

    公开(公告)日:2003-08-05

    申请号:US09708688

    申请日:2000-11-09

    IPC分类号: G01N3100

    摘要: Workstation, apparatuses and methods for the high-throughput synthesis, screening and/or characterization of combinatorial libraries. The invention relates to an array, which permits various high-throughput methods for synthesis, screening and/or characterization in the same array, without requiring sample transfer from the array. In a preferred embodiment, the synthesis, screening, and/or characterization steps are carried out in a highly parallel fashion, where more than one compound is synthesized, screened, and/or characterized at the same time. The invention may be practiced at the microscale. The array may comprise thermal channels, for regulating the temperature of the wells in the array. The wells of the array may comprise a membrane, which is used in various screening and characterization methods. The invention also relates to a covered array, comprising the array and an array cover, as well as an apparatus comprising the array, which comprises the array, an array cover and a stage. The array, array cover, and the stage may be modified as required for a variety of synthesis and/or analysis techniques. The array is easily interchangeable between different analytical instruments, and in an embodiment, the invention relates to an automated workstation, where the array is transferred between different synthesis, screening, and characterization stations. The invention also relates to a variety of methods for synthesis, screening, and characterization, which are adapted for combinatorial chemistry. Any of the embodiments of the invention may be used either alone or taken in various combinations.

    摘要翻译: 组合库的高通量合成,筛选和/或表征的工作站,设备和方法。 本发明涉及阵列,其允许在相同阵列中进行合成,筛选和/或表征的各种高通量方法,而不需要从阵列转移样品。 在优选实施方案中,合成,筛选和/或表征步骤以高度平行的方式进行,其中多于一种化合物被同时合成,筛选和/或表征。 本发明可以在微尺度下实施。 阵列可以包括用于调节阵列中的阱的温度的热通道。 阵列的孔可以包括膜,其用于各种筛选和表征方法。 本发明还涉及包括阵列和阵列盖的覆盖阵列,以及包括阵列的装置,其包括阵列,阵列盖和台。 可以根据各种合成和/或分析技术的要求来修改阵列,阵列覆盖物和载物台。 该阵列在不同的分析仪器之间易于互换,并且在一个实施例中,本发明涉及自动化工作站,其中阵列在不同的合成,筛选和表征台之间传送。 本发明还涉及适用于组合化学的各种合成,筛选和表征的方法。 本发明的任何实施方案可以单独使用或以各种组合使用。

    Reaction calorimeter and differential scanning calorimeter for the high-throughput synthesis, screening and characterization of combinatorial libraries
    2.
    发明授权
    Reaction calorimeter and differential scanning calorimeter for the high-throughput synthesis, screening and characterization of combinatorial libraries 失效
    用于高通量合成,筛选和表征组合文库的反应量热计和差示扫描量热计

    公开(公告)号:US07033840B1

    公开(公告)日:2006-04-25

    申请号:US09708687

    申请日:2000-11-09

    IPC分类号: G01N25/20 G01N31/10

    摘要: Workstation, apparatuses and methods for the high-throughput synthesis, screening and/or characterization of combinatorial libraries. The invention relates to an array, which permits various high-throughput methods for synthesis, screening and/or characterization in the same array, without requiring sample transfer from the array. In a preferred embodiment, the synthesis, screening, and/or characterization steps are carried out in a highly parallel fashion, where more than one compound is synthesized, screened, and/or characterized at the same time. The invention may be practiced at the microscale. The array may comprise thermal channels, for regulating the temperature of the wells in the array. The wells of the array may comprise a membrane, which is used in various screening and characterization methods. The invention also relates to a covered array, comprising the array and an array cover, as well as an apparatus comprising the array, which comprises the array, an array cover and a stage. The array, array cover, and the stage may be modified as required for a variety of synthesis and/or analysis techniques. The array is easily interchangeable between different analytical instruments, and in an embodiment, the invention relates to an automated workstation, where the array is transferred between different synthesis, screening, and characterization stations. The invention also relates to a variety of methods for synthesis, screening, and characterization, which are adapted for combinatorial chemistry. Any of the embodiments of the invention may be used either alone or taken in various combinations.

    摘要翻译: 用于组合库的高通量合成,筛选和/或表征的工作站,设备和方法。 本发明涉及阵列,其允许在相同阵列中进行合成,筛选和/或表征的各种高通量方法,而不需要从阵列转移样品。 在优选实施方案中,合成,筛选和/或表征步骤以高度平行的方式进行,其中多于一种化合物被同时合成,筛选和/或表征。 本发明可以在微尺度下实施。 阵列可以包括用于调节阵列中的阱的温度的热通道。 阵列的孔可以包括膜,其用于各种筛选和表征方法。 本发明还涉及包括阵列和阵列盖的覆盖阵列,以及包括阵列的装置,其包括阵列,阵列盖和台。 可以根据各种合成和/或分析技术的要求来修改阵列,阵列覆盖物和载物台。 该阵列在不同的分析仪器之间易于互换,并且在一个实施例中,本发明涉及自动化工作站,其中阵列在不同的合成,筛选和表征台之间传送。 本发明还涉及适用于组合化学的各种合成,筛选和表征的方法。 本发明的任何实施方案可以单独使用或以各种组合使用。

    Compliant walled combustion devices
    3.
    发明授权
    Compliant walled combustion devices 失效
    合适的围墙燃烧装置

    公开(公告)号:US07237524B2

    公开(公告)日:2007-07-03

    申请号:US11134077

    申请日:2005-05-19

    IPC分类号: F02B75/22 F02F3/00

    CPC分类号: F02B75/36

    摘要: Combustion devices described herein comprise a compliant combustion chamber wall or segment. The compliant segment deforms during combustion in the combustion chamber. Some devices may include a compliant wall configured to stretch responsive to pressure generated by combustion of a fuel in the combustion chamber. A coupling portion translates deformation of the compliant segment or wall into mechanical output. One or more ports are configured to inlet an oxygen source and fuel into the combustion chamber and to outlet exhaust gases from the combustion chamber.

    摘要翻译: 本文所述的燃烧装置包括顺应性燃烧室壁或段。 在燃烧室内的燃烧过程中,柔性段变形。 一些装置可以包括被配置为响应于燃烧室中的燃料燃烧产生的压力而拉伸的柔性壁。 联接部分将柔性段或壁的变形转换成机械输出。 一个或多个端口被配置为将氧源和燃料引入燃烧室并排出来自燃烧室的废气。

    Compliant walled combustion devices
    4.
    发明申请
    Compliant walled combustion devices 失效
    合适的围墙燃烧装置

    公开(公告)号:US20060000214A1

    公开(公告)日:2006-01-05

    申请号:US11134077

    申请日:2005-05-19

    IPC分类号: F01K27/00

    CPC分类号: F02B75/36

    摘要: Combustion devices described herein comprise a compliant combustion chamber wall or segment. The compliant segment deforms during combustion in the combustion chamber. Some devices may include a compliant wall configured to stretch responsive to pressure generated by combustion of a fuel in the combustion chamber. A coupling portion translates deformation of the compliant segment or wall into mechanical output. One or more ports are configured to inlet an oxygen source and fuel into the combustion chamber and to outlet exhaust gases from the combustion chamber.

    摘要翻译: 本文所述的燃烧装置包括顺应性燃烧室壁或段。 在燃烧室内的燃烧过程中,柔性段变形。 一些装置可以包括被配置为响应于燃烧室中的燃料燃烧产生的压力而拉伸的柔性壁。 联接部分将柔性段或壁的变形转换成机械输出。 一个或多个端口被配置为将氧源和燃料引入燃烧室并排出来自燃烧室的废气。

    Wide range oxygen sensor
    5.
    发明授权
    Wide range oxygen sensor 失效
    宽范围氧传感器

    公开(公告)号:US5360528A

    公开(公告)日:1994-11-01

    申请号:US916555

    申请日:1992-07-20

    IPC分类号: G01N27/419

    CPC分类号: G01N27/419

    摘要: A wide range oxygen sensor is provided which operates partially in the diffusion limited current mode to provide an output which is proportional to the oxygen partial pressure in a gas mixture which is sensed, such as the exhaust gas of an automotive internal combustion engine. The wide range oxygen sensor is constructed to have a planar structure with a single solid electrolyte layer that is shared by electrochemical storage, pumping and reference cells and which is deposited using known thermal deposition techniques. As a result, the wide range oxygen sensor of the present invention is characterized as being relatively low cost and readily producible under mass production conditions. Moreover, the wide range oxygen sensor is capable of rapidly and accurately sensing the exhaust gas oxygen partial pressure while the engine is operating in either the fuel-rich or fuel-lean condition to enable the evaluation of the air-to-fuel ratio of the precombustion fuel mixture.

    摘要翻译: 提供了一种宽范围的氧传感器,其以扩散限制电流模式部分地工作,以提供与所感测的气体混合物(例如汽车内燃机的排气)中的氧气分压成比例的输出。 宽范围氧传感器被构造成具有通过电化学存储,泵送和参考电池共享的单个固体电解质层的平面结构,并且使用已知的热沉积技术进行沉积。 结果,本发明的范围广泛的氧传感器的特征在于成本相对较低,并且在大规模生产条件下容易生产。 此外,当发动机在富燃料或贫燃料条件下运行时,宽范围氧传感器能够快速且准确地感测排气氧分压,以便能够评估燃料浓度 预燃燃料混合物。

    ELECTROACTIVE POLYMER MANUFACTURING
    6.
    发明申请
    ELECTROACTIVE POLYMER MANUFACTURING 审中-公开
    电动聚合物制造

    公开(公告)号:US20120169184A1

    公开(公告)日:2012-07-05

    申请号:US13363692

    申请日:2012-02-01

    IPC分类号: H01L41/047

    摘要: Described herein are transducers and their fabrication. The transducers convert between mechanical and electrical energy. Some transducers of the present invention include a pre-strained polymer. The pre-strain improves the conversion between electrical and mechanical energy. The present invention provides methods for fabricating electromechanical devices including one or more electroactive polymers.

    摘要翻译: 这里描述的是换能器及其制造。 换能器在机械和电能之间转换。 本发明的一些换能器包括预应变聚合物。 预应变改善了电和机械能之间的转换。 本发明提供了制造包括一种或多种电活性聚合物的机电装置的方法。

    COMPLIANT WALLED COMBUSTION DEVICES
    7.
    发明申请
    COMPLIANT WALLED COMBUSTION DEVICES 失效
    合适的壁挂式燃烧装置

    公开(公告)号:US20090241894A1

    公开(公告)日:2009-10-01

    申请号:US12346616

    申请日:2008-12-30

    IPC分类号: F02B75/32

    CPC分类号: F02B75/36

    摘要: Combustion devices described herein comprise a compliant combustion chamber wall or segment. The compliant segment deforms during combustion in the combustion chamber. Some devices may include a compliant wall configured to stretch responsive to pressure generated by combustion of a fuel in the combustion chamber. A coupling portion translates deformation of the compliant segment or wall into mechanical output. One or more ports are configured to inlet an oxygen source and fuel into the combustion chamber and to outlet exhaust gases from the combustion chamber.

    摘要翻译: 本文所述的燃烧装置包括顺应性燃烧室壁或段。 在燃烧室内的燃烧过程中,柔性段变形。 一些装置可以包括被配置为响应于燃烧室中的燃料燃烧产生的压力而拉伸的柔性壁。 联接部分将柔性段或壁的变形转换成机械输出。 一个或多个端口被配置为将氧源和燃料引入燃烧室并排出来自燃烧室的废气。

    Selective gas sensor
    9.
    发明授权
    Selective gas sensor 失效
    选择性气体传感器

    公开(公告)号:US5689059A

    公开(公告)日:1997-11-18

    申请号:US696550

    申请日:1996-08-14

    IPC分类号: G01N25/28 G01N33/00 G01N7/00

    摘要: A selective gas sensor (10) for detecting a particular compound, or group of compounds, such as non-methane hydrocarbons, within a high temperature gas stream (12) includes an oxygen generation system (14) positioned over an oxygen diffusion region (15). The oxygen generation system (14) and the oxygen diffusion region (15) provide oxygen through a medial temperature control zone (20) to a sensing element (16). The temperature and flux of hydrocarbon components within the high temperature gas stream (12) are regulated by components within the high temperature control zone (20) and by an external temperature control zone (22) in thermal contact with the sensing element (16).

    摘要翻译: 用于在高温气流(12)内检测特定化合物或一组化合物(例如非甲烷烃)的选择性气体传感器(10)包括位于氧扩散区(15)上方的氧气产生系统(14) )。 氧气产生系统(14)和氧气扩散区域(15)通过内部温度控制区(20)向感测元件(16)提供氧气。 高温气流(12)内的烃组分的温度和流量由高温控制区(20)内的组分和与感测元件(16)热接触的外部温度控制区(22)调节。