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公开(公告)号：US20200010868A1
公开(公告)日：2020-01-09
申请号：US16460118
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark Huffman , Joshua Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
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公开(公告)号：US11795445B2
公开(公告)日：2023-10-24
申请号：US17316165
申请日：2021-05-10
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
CPC classification number: C12N9/90 , C12N15/52 , C12N15/74 , C12N15/815 , C12Y504/02007
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20220243183A1
公开(公告)日：2022-08-04
申请号：US17617533
申请日：2020-06-30
Applicant: Codexis, Inc.
Inventor： Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian
Abstract: The present invention provides engineered sucrose phosphorylase (SP) enzymes, polypeptides having SP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing SP enzymes are also provided. The present invention further provides compositions comprising the SP enzymes and methods of using the engineered SP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20240060064A1
公开(公告)日：2024-02-22
申请号：US18467259
申请日：2023-09-14
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
CPC classification number: C12N9/90 , C12N15/52 , C12N15/74 , C12N15/815 , C12Y504/02007
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US11274286B2
公开(公告)日：2022-03-15
申请号：US16460118
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark A. Huffman , Joshua N. Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
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Patent Agency Ranking
公开(公告)号：US20240076647A1
公开(公告)日：2024-03-07
申请号：US18503542
申请日：2023-11-07
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark A. Huffman , Joshua N. Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
IPC: C12N9/88
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
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公开(公告)号：US11845968B2
公开(公告)日：2023-12-19
申请号：US17592869
申请日：2022-02-04
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark A. Huffman , Joshua N. Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
CPC classification number: C12N9/88 , C12N15/63 , C12P21/02 , C12Y401/02004
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
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公开(公告)号：US11034948B2
公开(公告)日：2021-06-15
申请号：US16460062
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant Murphy , Nicholas M. Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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公开(公告)号：US20240026401A1
公开(公告)日：2024-01-25
申请号：US18024942
申请日：2021-09-17
Applicant: Codexis, Inc.
Inventor： Santhosh Sivaramakrishnan , Ericka Bermudez , Nandhitha Subramanian , David Entwistle , Stephanie Marie Forget
CPC classification number: C12P17/182 , C12N9/1096 , C12Y206/01018
Abstract: The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.
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公开(公告)号：US20230374486A1
公开(公告)日：2023-11-23
申请号：US18247866
申请日：2021-10-05
Applicant: Codexis, Inc.
Inventor： Jonathan Vroom , Santhosh Sivaramakrishnan , Jessica Anna Hurtak
IPC: C12N9/90
CPC classification number: C12N9/90 , C12Y504/02007
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
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