-
公开(公告)号：US12071642B2
公开(公告)日：2024-08-27
申请号：US18462237
申请日：2023-09-06
Applicant: Codexis, Inc. , Societe des Produits Nestle S.A.
Inventor： Chinping Chng , Nikki Dellas , Da Duan , Ravi David Garcia , Harvinder Chagger Maniar
CPC classification number: C12N9/2414 , A61K38/47 , A61P1/18 , C12Y302/01001
Abstract: The present invention provides engineered amylase polypeptides and compositions thereof. The engineered amylase polypeptides have been optimized to provide improved thermostability, protease stability, and stability under a range of pH conditions, including acidic (pH
-
公开(公告)号：US20220162580A1
公开(公告)日：2022-05-26
申请号：US17592869
申请日：2022-02-04
Applicant: Codexis, Inc.
Inventor： Da Duan , Oscar Alvizo , Jovana Nazor , Harvinder Chagger Maniar , James Nicholas Riggins , Jonathan Vroom , Santhosh Sivaramakrishnan , Hao Yang , Anna Fryszkowska , Mark A. Huffman , Joshua N. Kolev , Iman Farasat , Agustina Rodriguez-Granillo , Deeptak Verma
IPC: C12N9/88
Abstract: The present invention provides engineered deoxyribose-phosphate aldolase polypeptides useful under industrial process conditions for the production of pharmaceutical and fine chemical compounds.
-
公开(公告)号：US20220090038A1
公开(公告)日：2022-03-24
申请号：US17460147
申请日：2021-08-27
Applicant: Codexis, Inc. , Societe des Produits Nestle S.A.
Inventor： Chinping Chng , Nikki Dellas , Da Duan , Ravi David Garcia , Harvinder Chagger Maniar
Abstract: The present invention provides engineered amylase polypeptides and compositions thereof. The engineered amylase polypeptides have been optimized to provide improved thermostability, protease stability, and stability under a range of pH conditions, including acidic (pH
-
公开(公告)号：US20210261940A1
公开(公告)日：2021-08-26
申请号：US17316165
申请日：2021-05-10
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant S. Murphy , Nicholas Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
-
公开(公告)号：US10745681B2
公开(公告)日：2020-08-18
申请号：US15861849
申请日：2018-01-04
Applicant: Codexis, Inc.
Inventor： Oscar Alvizo , David Elgart , Robert Kevin Orr , James Nicholas Riggins , Anna Fryszkowska , Katrina W. Lexa , Xiang Yi , Da Duan , Courtney Dianne Moffett , Nikki Dellas , Vesna Mitchell
Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.
-
Patent Agency Ranking
公开(公告)号：US20200010823A1
公开(公告)日：2020-01-09
申请号：US16460062
申请日：2019-07-02
Applicant: Codexis, Inc.
Inventor： Scott J. Novick , Xiang Yi , Nikki Dellas , Oscar Alvizo , Jovana Nazor , Da Duan , Vesna Mitchell , Jonathan Vroom , Santhosh Sivaramakrishnan , Nandhitha Subramanian , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Grant Murphy , Nicholas M. Marshall , Jay Russell , Keith A. Canada
Abstract: The present invention provides engineered phosphopentomutase (PPM) enzymes, polypeptides having PPM activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PPM enzymes are also provided. The present invention further provides compositions comprising the PPM enzymes and methods of using the engineered PPM enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
-
公开(公告)号：US12084697B2
公开(公告)日：2024-09-10
申请号：US18158339
申请日：2023-01-23
Applicant: Codexis, Inc.
Inventor： Oscar Alvizo , David Elgart , Robert Kevin Orr , James Nicholas Riggins , Anna Fryszkowska , Katrina W. Lexa , Xiang Yi , Da Duan , Courtney Dianne Moffett , Nikki Dellas , Vesna Mitchell
CPC classification number: C12N9/84 , C07K14/62 , C12P21/02 , C12Y305/01011 , C07K2319/21
Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.
-
公开(公告)号：US20240026331A1
公开(公告)日：2024-01-25
申请号：US18315466
申请日：2023-05-10
Applicant: Codexis, Inc.
Inventor： Arianna I. Celis Luna , Da Duan , Paul Campion Jordan , Kathleen Susan Molnar , Adam P. Silverman , Tricia Windgassen
CPC classification number: C12N9/63 , C12Y304/21026 , A61P1/14 , C07K2319/02 , A61K38/00
Abstract: The present disclosure relates to methods of expressing recombinant neprosin polypeptide, host cells and expression vectors for expressing the recombinant neprosin polypeptide, and methods of using the expressed neprosin polypeptide for therapeutic and other purposes.
-
公开(公告)号：US11767519B2
公开(公告)日：2023-09-26
申请号：US17460147
申请日：2021-08-27
Applicant: Codexis, Inc. , Societe des Produits Nestle S.A.
Inventor： Chinping Chng , Nikki Dellas , Da Duan , Ravi David Garcia , Harvinder Chagger Maniar
CPC classification number: C12N9/2414 , A61K38/47 , A61P1/18 , C12Y302/01001
Abstract: The present invention provides engineered amylase polypeptides and compositions thereof. The engineered amylase polypeptides have been optimized to provide improved thermostability, protease stability, and stability under a range of pH conditions, including acidic (pH
-
公开(公告)号：US11591588B2
公开(公告)日：2023-02-28
申请号：US17091479
申请日：2020-11-06
Applicant: Codexis, Inc.
Inventor： Oscar Alvizo , David Elgart , Robert Kevin Orr , James Nicholas Riggins , Anna Fryszkowska , Katrina W. Lexa , Xiang Yi , Da Duan , Courtney Dianne Moffett , Nikki Dellas , Vesna Mitchell
Abstract: The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.
-
-
-
-
-
-
-
-
-
Search Results
44
records
(took 0.019 seconds)
