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    Latching micro-regulator
    1.
    发明申请
    Latching micro-regulator 有权
    闭锁微调节器

    公开(公告)号：US20030172975A1

    公开(公告)日：2003-09-18

    申请号：US10179537

    申请日：2002-06-24

    Applicant: Coventor, Inc.

    Inventor： John Richard Gilbert ,  Bernard Bunner ,  Sebastian Bohm ,  Manish Deshpande

    IPC: F17D001/00

    CPC classification number: F16K99/0001 ,  F15C5/00 ,  F16K99/0005 ,  F16K99/0007 ,  F16K99/0009 ,  F16K99/0015 ,  F16K99/0046 ,  F16K99/0048 ,  F16K2099/0069 ,  F16K2099/0071 ,  F16K2099/0074 ,  F16K2099/0076 ,  F16K2099/008 ,  F16K2099/0084 ,  G05D7/0694 ,  Y10T29/49412 ,  Y10T137/87314

    Abstract: A latching microregulator for regulating liquid flow on micro-scale levels comprises a substrate having an inlet port and an outlet port, a valve element defining a valve chamber for opening and closing the inlet port, and an actuator assembly for actuating the valve element. The valve chamber is configured to contain a volume of fluid, and the inlet port and the outlet port are in fluid communication with the valve chamber to provide a liquid flow path through the chamber. The actuator assembly comprises a cantilever beam for moving the valve element between an open position and a closed position, an actuator, such as a piezoelectric element, for moving the cantilever beam, and a latch, such as a permanent magnet, for securing the cantilever beam in the closed position. A flow regulation system comprises a plurality of fluid channels of varied flow conductance and a plurality of latching microregulators for selectively blocking or allowing flow through each of the fluid channels.

    Abstract translation: 用于调节微量级液体流动的闭锁微调节器包括具有入口端口和出口端口的基板，限定用于打开和关闭入口端口的阀室的阀元件以及用于致动阀元件的致动器组件。 阀室被构造成容纳一定体积的流体，并且入口端口和出口端口与阀室流体连通以提供通过该腔室的液体流动路径。 致动器组件包括用于在打开位置和关闭位置之间移动阀元件的悬臂梁，用于移动悬臂梁的致动器（例如压电元件）以及用于固定悬臂的闩锁（例如永磁体） 梁处于关闭位置。 流量调节系统包括多个不同流量的流体通道和多个用于选择性地阻塞或允许流过每个流体通道的闭锁微调节器。

    On chip dilution system
    2.
    发明申请
    On chip dilution system 有权
    片上稀释系统

    公开(公告)号：US20030210607A1

    公开(公告)日：2003-11-13

    申请号：US10183726

    申请日：2002-06-25

    Applicant: Coventor, Inc.

    Inventor： John Gilbert ,  Manish Deshpande

    IPC: B01F005/00

    CPC classification number: B01F3/088 ,  B01F13/0059 ,  B01F15/00019 ,  B01F15/00064 ,  B01F2003/0896 ,  B01L3/502738 ,  B01L2200/148 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0655 ,  B01L2400/082 ,  Y10T137/2499 ,  Y10T137/7736 ,  Y10T137/87676 ,  Y10T137/87684 ,  Y10T436/10 ,  Y10T436/25625

    Abstract: An on-chip chemical compound dilution system for providing dilution of a chemical compound in a microfluidic application includes at least one sample well for providing a selected chemical compound to be diluted, a dilution well for providing a diluent for diluting the chemical compound, a network of channels for carrying the chemical compound and diluent, a first syringe pump for effecting dilution, a second syringe pump, a detector and a plurality of valves for selectively controlling the flow of liquid through the channels. The dilution system may be a multiple-stage dilution system for precisely mixing a plurality of chemical compounds in a diluent. The dilution system allows for accurate calibration to compensate for variations due to manufacturing, thereby providing precise dilution ratios. The dilution system further enables flushing to allow re-use of the system with another chemical compound.

    Abstract translation: 用于在微流体应用中提供化学化合物稀释的片上化学稀释系统包括至少一个用于提供所要稀释的化学化合物的样品孔，用于提供用于稀释化合物的稀释剂的稀释液，网络 用于运送化合物和稀释剂的通道，用于稀释的第一注射泵，第二注射器泵，检测器和用于选择性地控制通过通道的液体流动的多个阀。 稀释系统可以是用于在稀释剂中精确混合多种化合物的多级稀释系统。 稀释系统允许精确的校准来补偿由于制造造成的变化，从而提供精确的稀释比。 稀释系统还可以冲洗以允许再次使用另一种化合物的系统。

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