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公开(公告)号:US20050170427A1
公开(公告)日:2005-08-04
申请号:US11101271
申请日:2005-04-06
申请人: Ralph Chappa , Sheau-Ping Hu , Dale Swan , Melvin Swanson , Patrick Guire
发明人: Ralph Chappa , Sheau-Ping Hu , Dale Swan , Melvin Swanson , Patrick Guire
IPC分类号: G01N33/53 , C07B61/00 , C07C45/63 , C07C235/84 , C07C323/42 , C07H21/00 , C12M1/00 , C12N15/09 , C12Q1/68 , C12Q1/6834 , C40B40/06 , C40B60/14 , G01N1/28 , G01N21/78 , G01N33/566 , G01N37/00 , C07H21/04 , C12M1/34
CPC分类号: B82Y30/00 , B01J2219/00317 , B01J2219/00531 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00711 , B01J2219/00716 , B01J2219/00722 , C07B2200/11 , C07C45/63 , C07C235/84 , C07C323/42 , C07H21/00 , C12Q1/6834 , C40B40/06 , C40B60/14 , C07C49/813
摘要: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
摘要翻译: 用于将目标分子(例如核酸)共价连接到基底表面上的方法和试剂组合物。 试剂组合物包括能够共价结合靶分子的基团。 任选地,组合物可以含有用于将试剂组合物附着到表面上的光反应性基团。 试剂组合物可用于提供用于制备核酸微阵列的活性载玻片。
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公开(公告)号:US20080090959A1
公开(公告)日:2008-04-17
申请号:US11975259
申请日:2007-10-18
申请人: Dale Swan , Melvin Swanson
发明人: Dale Swan , Melvin Swanson
IPC分类号: C08G63/48
CPC分类号: C40B80/00 , B01J2219/00317 , B01J2219/00531 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00711 , B01J2219/00716 , B01J2219/00722 , B82Y30/00 , C07B2200/11 , C07C45/63 , C07C235/84 , C07C323/42 , C07H21/00 , C08L63/00 , C09D4/00 , C12Q1/6834 , C40B40/06 , C40B60/14 , C07C49/813
摘要: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes epoxide groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
摘要翻译: 用于将目标分子(例如核酸)共价连接到基底表面上的方法和试剂组合物。 试剂组合物包括能够与靶分子共价结合的环氧基。 任选地,组合物可以含有用于将试剂组合物附着到表面上的光反应性基团。 试剂组合物可用于提供用于制备核酸微阵列的活性载玻片。
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公开(公告)号:US20050074478A1
公开(公告)日:2005-04-07
申请号:US10677022
申请日:2003-10-01
申请人: Ronald Ofstead , Melvin Swanson , Dale Swan
发明人: Ronald Ofstead , Melvin Swanson , Dale Swan
IPC分类号: B01J19/00 , C07H21/00 , C08F8/00 , C08F220/56 , C12Q1/68 , C40B40/06 , C40B60/14 , G01N33/543 , C12M1/34 , A61F2/00 , B32B27/00
CPC分类号: C07H21/00 , B01J2219/00387 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , C08F8/00 , C08F2800/10 , C08F2800/20 , C40B40/06 , C40B60/14 , G01N33/54353 , Y10T428/31855 , C08F220/54 , C08F220/56
摘要: The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present invention relates to surfaces coated with a polymer according to the present invention. In an embodiment, the present invention relates to methods for thermochemically and/or photochemically attaching molecules to a surface at a high density.
摘要翻译: 本发明涉及可用于例如固定生物分子例如核酸和蛋白质的方法,试剂和底物。 在一个实施方案中,本发明涉及涂覆有根据本发明的聚合物的表面。 在一个实施方案中,本发明涉及以高密度将分子热化学和/或光化学连接到表面上的方法。
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公开(公告)号:US20060009122A1
公开(公告)日:2006-01-12
申请号:US10889399
申请日:2004-07-12
申请人: Melvin Swanson
发明人: Melvin Swanson
IPC分类号: A01K51/00
CPC分类号: A01N37/02 , A01N25/18 , A01N25/10 , A01N2300/00
摘要: The invention provides controlled release compositions for treatment of parasitic mites in honeybees, the compositions composed of a covalently crosslinked polymer gel and an active agent that includes a salt of formic acid. The invention also provides methods for controlling parasitic mites in honeybees, the methods involving treating the honeybees with a controlled release composition composed a covalently crosslinked polymer gel and an active agent that includes a salt of formic acid. The invention further provides a kit for treatment of parasitic mites in honeybees, the kit including an envelope that contains a controlled release composition of the invention. Optionally, the active agent can include formic acid.
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