Method of using (H.sup.+ /K.sup.+)ATPase inhibitors as antiviral agents
    7.
    发明授权
    Method of using (H.sup.+ /K.sup.+)ATPase inhibitors as antiviral agents 失效
    使用(H + / K +)ATP酶抑制剂作为抗病毒剂的方法

    公开(公告)号:US5945425A

    公开(公告)日:1999-08-31

    申请号:US737251

    申请日:1996-10-24

    摘要: A class of compounds which are (H.sup.+ /K.sup.+)ATPase inhibitors can be used for the treatment of viral infections. Compounds of particular interest are defined by Formula III: ##STR1## wherein D is N or CH; wherein R.sup.7 is one or more radicals selected from hydrido, alkoxy, amino, cyano, nitro, hydroxyl, alkyl, halo, haloalkyl, carboxyl, alkanoyl, nitro, amino, alkylamino, aminocarbonyl, aminosulfonyl, alkylaminocarbonyl, alkylcarbonylamino, alkoxycarbonyl, alkylaminosulfonyl, alkylsulfonylamino, alkylthio, alkylsulfinyl and alkylsulfonyl; wherein R.sup.8 is selected from hydrido, alkyl and cycloalkyl; wherein R.sup.9 is one or more radicals selected from hydrido, alkoxy, amino, alkyl, halo, cyano, nitro, hydroxyl, haloalkyl, nitro, carboxyl, alkanoyl, amino, alkylamino, dialkylamino, aminocarbonyl, alkylaminocarbonyl, alkylcarbonylamino, aminosulfonyl, alkylaminosulfonyl, alkylsulfonylamino, alkoxycarbonyl, alkylthio, alkylsulfinyl and alkylsulfonyl; and wherein R.sup.10 and R.sup.11 are independently selected from hydrido, alkyl, aryl, alkylcarbonyl and arylcarbonyl wherein the aryl ring may be further substituted with one or more radicals selected from alkyl, halo, hydrazidylcarbonyl, aminocarbonyl and alkoxy; or wherein R.sup.10 and R.sup.11 together with the nitrogen atom form a heterocyclic ring.

    摘要翻译: PCT No.PCT / US95 / 05021 Sec。 371日期1996年10月24日第 102(e)日期1996年10月24日PCT提交1995年5月1日PCT公布。 出版物WO95 / 29897 1995年11月9日,一类(H + / K +)ATP酶抑制剂的化合物可用于治疗病毒感染。 特别感兴趣的化合物由式III定义:其中D是N或CH; 其中R7是一个或多个选自氢,烷氧基,氨基,氰基,硝基,羟基,烷基,卤素,卤代烷基,羧基,烷酰基,硝基,氨基,烷基氨基,氨基羰基,氨基磺酰基,烷基氨基羰基,烷基羰基氨基,烷氧基羰基,烷基氨基磺酰基, ,烷硫基,烷基亚磺酰基和烷基磺酰基; 其中R8选自氢,烷基和环烷基; 其中R9是一个或多个选自氢,烷氧基,氨基,烷基,卤素,氰基,硝基,羟基,卤代烷基,硝基,羧基,烷酰基,氨基,烷基氨基,二烷基氨基,氨基羰基,烷基氨基羰基,烷基羰基氨基,氨基磺酰基,烷基氨基磺酰基, ,烷氧基羰基,烷硫基,烷基亚磺酰基和烷基磺酰基; 并且其中R 10和R 11独立地选自氢,烷基,芳基,烷基羰基和芳基羰基,其中所述芳基环可以进一步被一个或多个选自烷基,卤素,肼基羰基,氨基羰基和烷氧基的基团取代; 或其中R 10和R 11与氮原子一起形成杂环。

    DRIVING UNIT, GATE DRIVING CIRCUIT, ARRAY SUBSTRATE, AND DISPLAY APPARATUS

    公开(公告)号:US20220246075A2

    公开(公告)日:2022-08-04

    申请号:US17481376

    申请日:2021-09-22

    IPC分类号: G09G3/20

    摘要: The present disclosure relates to a driving unit. The driving unit may include a first driving sub-circuit, a second driving sub-circuit, and a driving control circuit. The first driving sub-circuit may include a plurality of first switching elements, and at least some of the plurality of first switching elements may be configured to output a first signal to a first output terminal of the driving unit in response to a control signal from the driving control circuit. The second driving sub-circuit may include one or more second switching elements, and at least one of the one or more second switching elements may be configured to output a second signal to a second output terminal of the driving unit in response to the control signal from the driving control circuit. The driving control circuit may be configured to output the control signal at a control signal output terminal.